Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells

Lung Cancer

Volumn 68, Issue 3, 2010, Pages 355-365

  Hung, Jen Yu ^a,b,c   Hsu, Ya Ling ^a   Ni, Wen Chiu ^a   Tsai, Ying Ming ^c   Yang, Chih Jen ^b,c   Kuo, Po Lin ^a,c   Huang, Ming Shyan ^a,b,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Dehydrocostuslactone; Endoplasmic reticulum stress; Non small cell lung cancer; ROS

Indexed keywords

CASPASE 4; DEHYDROCOSTUS LACTONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOTRANSFERASE; PKR LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN IRE1; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; CALCIUM; CASP4 PROTEIN, HUMAN; DDIT3 PROTEIN, HUMAN; DNA BINDING PROTEIN; ERN2 PROTEIN, HUMAN; INITIATOR CASPASE; LACTONE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PERK KINASE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; REGULATORY FACTOR X TRANSCRIPTION FACTORS; RIBONUCLEASE; SESQUITERPENE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA SPLICING; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CANCER TRANSPLANTATION; CARCINOMA, NON-SMALL-CELL LUNG; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENETICS; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; APOPTOSIS; CALCIUM; CARCINOMA, NON-SMALL-CELL LUNG; CASPASES, INITIATOR; CELL LINE, TUMOR; DNA-BINDING PROTEINS; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; HUMANS; LACTONES; LUNG NEOPLASMS; MEMBRANE PROTEINS; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEOPLASM TRANSPLANTATION; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; SESQUITERPENES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TUMOR BURDEN;

EID: 77952543940     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2009.07.017     Document Type: Article

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