Nanosized cationic hydrogels for drug delivery: Preparation, properties and interactions with cells

Advanced Drug Delivery Reviews

Volumn 54, Issue 1, 2002, Pages 135-147

  Vinogradov, Serguei V ^a   Bronich, Tatiana K ^a   Kabanov, Alexander V ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Drug delivery; Drug targeting; Formulation; Nanogel; Poly(ethylene glycol); Polyethyleneimine; Polynucleotides

Indexed keywords

BRAIN; CROSSLINKING; HYDROPHILICITY; HYDROPHOBICITY; NANOSTRUCTURED MATERIALS; POLYETHYLENE OXIDES; POSITIVE IONS;

HYDROPHILIC POLYMERS;

HYDROGELS;

AMPHOPHILE; ANION; CATION; DRUG CARRIER; INDOMETACIN; LIGAND; MACROGOL; OLIGONUCLEOTIDE; POLYETHYLENEIMINE; POLYPEPTIDE; RETINOIC ACID;

BIOAVAILABILITY; BLOOD BRAIN BARRIER; CELL TRANSPORT; DRUG DELIVERY SYSTEM; HYDROGEL; HYDROPHOBICITY; IMMOBILIZATION; INTESTINE EPITHELIUM; PRIORITY JOURNAL; REVIEW;

EID: 0037122745     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(01)00245-9     Document Type: Article

References (66)

1. Nanoparticles and nanocapsules - New dosage forms in the nanometer size range
2. Nanoparticulate systems for the delivery of antisense oligonucleotides
3. Physiopathological and physicochemical considerations in targeting of colloids and drug carriers to the bone marrow
4. Oral vaccine delivery
5. Polymer-coated long-circulating microparticulate pharmaceuticals
6. MR lymphography: Evidence of extravasation of superparamagnetic nanoparticles into the lymph
7. Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor
8. Incorporation of polylactide-polyglycolide in a cortical defect: Neoangiogenesis and blood supply in a bone chamber
9. Local intraluminal infusion of biodegradable polymeric nanoparticles. A novel approach for prolonged drug delivery after balloon angioplasty
10. Poly(ethylene glycol)-polyethylenimine NanoGel particles: Novel drug delivery systems for antisense oligonucleotides
11. Block and graft copolymers and NanoGel copolymer networks for DNA delivery into cell
12. Hybrid nanogels for sustainable positive thermosensitive drug release
13. Molecular analysis of interpolymer complexation in graft copolymer networks
14. A new dispersion technique for micro- and nanoparticle formation of drug delivery carriers based on poly(acrylic acid)
15. Structure and flow properties of latexes containing carboxylic groups
16. Functionalised microgels: Novel stabilizers for catalytically active metal colloids
17. The interaction of thermosensitive, anionic microgels with metal ion solution species
18. Hydrogels in pharmaceutical formulations
19. Lipid-coated microgels for the triggered release of doxorubicin
20. Electrically modulated/flocculation of ultra-fine microgels
21. The preparation, characteriztion and applications of colloidal microgels
22. Molecular design of reactive microgels
23. Cross-linking self-emulsifying copolymerization of an unsaturated polyester and styrene
24. Reactive microgels by emulsion polymerization of unsaturated polyester resins
25. Influence of charge density on the swelling of colloidal poly(N-isopropylacrylamide-co-acrylic acid) microgels
26. Preparation and characterization of monodisperse polystyrene latexes III. Preparation without added surface active agents
27. Preparation and characterization of polymer latices formed in the absence of surface active agents
28. Charge controlled swelling of microgel particles
29. Equilibrium and kinetic aspects of the pH-dependent swelling of poly(2-vinylpyridine-co-styrene) microgels
30. Investigation of the swelling response and drug loading of ionic microgels: The dependence on functional group compositon
31. pH and ion-triggered volume response of anionic hydrogel microspheres
32. Poly[(methyl methacrylate)-co-(methacrylic acid)] microgel particles: Swelling control using pH, cononsolvency, and osmotic deswelling
33. Nanogels and microgels: The new polymeric materials playground
34. pH-dependent swelling of nano-sized poly(methacrylic acid-g-ethylene glycol) gels
35. Synthesis and light scattering study of hydroxypropyl cellulose microgels
36. Microencapsulation using emulsification/solvent evaporation: An overview of techniques and applications
37. Swelling of ionic gels: Quantitative performance of the Donnan theory
38. Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides
39. Polyelectrolyte gels
40. Interaction of nanosized copolymer networks with oppositely charged amphiphilic molecules
41. Absorption of ionic amphiphiles by oppositely charged polyelectrolyte gels
42. Novel drug delivery systems based on the complexes of block ionomers and surfactants of opposite charge
43. A study of the interaction of avidin with 2-anilinonaphthalene-6-sulfonic acid as a probe of the biotin binding site
44. Long circulating microparticulate drug carriers
45. In vitro and in vivo availability of liposomes
46. Targeting of colloids to lymph nodes: Influence of lymphatic physiology and colloidal characteristics
47. Localization of sterically stabilized liposomes in Klebsiella pneumoniae-infected rat lung tissue: Influence of liposome characteristics
48. Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice
49. Hyperthermia enables tumor-specific nanoparticle delivery: Effect of particle size
50. Uptake by hepatocytes and biliary excretion of intravenously administered polystyrene microspheres in rats
51. Taking polycation gene delivery systems from in vitro to in vivo
52. Enhancing antisense oligonucleotide efficacy in vivo by improving both antisense design using RNAse H accessibility mapping and sustained hippocampal delivery using biodegradeable microspheres
53. Receptor-mediated gene transfer to airway epithelial cells in primary culture
54. Enhanced anti-tumor effects with microencapsulated c-myc antisense oligonucleotide
55. Radiolabeling of methylphosphonate and phosphorothioate oligonucleotides and evaluation of their transport in everted rat jejunum sacs
56. Potential applications of polymers in the delivery of drugs to the central nervous system
57. Cell culture and animal studies for intracerebral delivery of borocaptate in liposomal formulation
58. Nanoparticulate systems for brain delivery of drugs
59. Human blood-brain barrier transferrin receptor
60. Identification and distribution of insulin receptors on cultured bovine brain microvessel endothelial cells: Possible function in insulin processing in the blood-brain barrier
61. Delivery across the blood-brain barrier of antisense directed against amyloid beta: Reversal of learning and memory deficits in mice overexpressing amyloid precursor protein