Accumulation of amyloid-like Aβ1-42 in AEL (autophagy-endosomal-lysosomal) vesicles: Potential implications for plaque biogenesis

ASN Neuro

Volumn 6, Issue 2, 2014, Pages 95-109

  Ling, Daijun ^a   Magallanes, Martha ^a   Salvaterra, Paul M ^a,b  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b Irell and Manella Graduate School of Biological Sciences   (United States)

Author keywords

AEL (autophagy endosomal lysosomal) vesicle; Alzheimer's disease; Amyloid

Indexed keywords

AMYLOID BETA PROTEIN ANTIBODY; AMYLOID BETA PROTEIN [1-40]; AMYLOID BETA PROTEIN [1-42]; AUTOPHAGY PROTEIN 5; CATHEPSIN D; CONGO RED; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; MIFEPRISTONE; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BIOGENESIS; BRAIN TISSUE; CELL FUNCTION; CELL FUSION; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DROSOPHILA; EMBRYO; ENDOSOME; ENZYME ACTIVITY; EXTRACELLULAR SPACE; FLUORESCENCE MICROSCOPY; HUMAN; IMMUNOHISTOCHEMISTRY; LYSOSOME; METABOLIC INHIBITION; MOLECULAR PROBE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; TURNOVER TIME; WESTERN BLOTTING; AGING; AMYLOID PLAQUE; AMYLOIDOSIS; ANIMAL; BRAIN; CELL CULTURE; CYTOPLASM VESICLE; DROSOPHILA MELANOGASTER; ENDOCYTOSIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NERVE CELL; NERVE DEGENERATION; PATHOLOGY; TRANSGENIC ANIMAL; ULTRASTRUCTURE;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOIDOSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AUTOPHAGY; BRAIN; CELL MEMBRANE; CELLS, CULTURED; CYTOPLASMIC VESICLES; DROSOPHILA MELANOGASTER; ENDOCYTOSIS; ENDOSOMES; EXTRACELLULAR SPACE; HUMANS; LYSOSOMES; NERVE DEGENERATION; NEURONS; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID;

EID: 84896301845     PISSN: 17590914     EISSN: None     Source Type: Journal    
DOI: 10.1042/AN20130044     Document Type: Article

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