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Volumn 5, Issue 7, 2010, Pages

Burn injury reduces neutrophil directional migration speed in microfluidic devices

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; ASSAY; BODY TEMPERATURE; BURN; CELL FUNCTION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN CELL; MALE; MICROFLUIDIC DEVICE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; PATIENT MONITORING; VALIDATION STUDY; CELL MOTION; CYTOLOGY; IMMUNOLOGY; METHODOLOGY; MICROFLUIDIC ANALYSIS; MIDDLE AGED; NEUTROPHIL; PATHOLOGY; PHYSIOLOGY;

EID: 77955630510     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011921     Document Type: Article
Times cited : (104)

References (66)
  • 1
    • 49149123244 scopus 로고    scopus 로고
    • Advances in surgical care: Management of severe burn injury
    • White CE, Renz EM (2008) Advances in surgical care: management of severe burn injury. Crit Care Med 36(7 Suppl): S318-324.
    • (2008) Crit Care Med , vol.36 , Issue.7 SUPPL. , pp. 318-324
    • White, C.E.1    Renz, E.M.2
  • 2
    • 41849131776 scopus 로고    scopus 로고
    • Closed-loop and decision-assist resuscitation of burn patients
    • Salinas J, Drew G, Gallagher J, Cancio LC, Wolf SE, et al. (2008) Closed-loop and decision-assist resuscitation of burn patients. J Trauma 64(4 Suppl): S321-332.
    • (2008) J Trauma , vol.64 , Issue.4 SUPPL.
    • Salinas, J.1    Drew, G.2    Gallagher, J.3    Cancio, L.C.4    Wolf, S.E.5
  • 3
    • 34248378252 scopus 로고    scopus 로고
    • The phenomenon of fluid creep in acute burn resuscitation
    • Saffle JI (2007) The phenomenon of fluid creep in acute burn resuscitation. J Burn Care Res 28(3): 382-395.
    • (2007) J Burn Care Res , vol.28 , Issue.3 , pp. 382-395
    • Saffle, J.I.1
  • 4
    • 33747434103 scopus 로고    scopus 로고
    • Advances in burn critical care
    • Ipaktchi K, Arbabi S (2006) Advances in burn critical care. Crit Care Med 34(9 Suppl): S239-244.
    • (2006) Crit Care Med , vol.34 , Issue.9 SUPPL. , pp. 239-244
    • Ipaktchi, K.1    Arbabi, S.2
  • 5
    • 32044459108 scopus 로고    scopus 로고
    • Meta-analysis of early excision of burns
    • Ong YS, Samuel M, Song C (2006) Meta-analysis of early excision of burns. Burns 32(2): 145-150.
    • (2006) Burns , vol.32 , Issue.2 , pp. 145-150
    • Ong, Y.S.1    Samuel, M.2    Song, C.3
  • 6
    • 0023792487 scopus 로고
    • Significant reductions in mortality for children with burn injuries through the use of prompt eschar excision
    • Tompkins RG, Remensnyder JP, Burke JF, Tompkins DM, Hilton JF, et al. (1988) Significant reductions in mortality for children with burn injuries through the use of prompt eschar excision. Ann Surg 208(5): 577-585.
    • (1988) Ann Surg , vol.208 , Issue.5 , pp. 577-585
    • Tompkins, R.G.1    Remensnyder, J.P.2    Burke, J.F.3    Tompkins, D.M.4    Hilton, J.F.5
  • 7
    • 0024549676 scopus 로고
    • A comparison of conservative versus early excision. Therapies in severely burned patients
    • Discussion 552-543
    • Herndon DN, Barrow RE, Rutan RL, Rutan TC, Desai MH, et al. (1989) A comparison of conservative versus early excision. Therapies in severely burned patients. Ann Surg 209(5): 547-552; discussion 552-543.
    • (1989) Ann Surg , vol.209 , Issue.5 , pp. 547-552
    • Herndon, D.N.1    Barrow, R.E.2    Rutan, R.L.3    Rutan, T.C.4    Desai, M.H.5
  • 8
    • 0036711656 scopus 로고    scopus 로고
    • Effects of delayed wound excision and grafting in severely burned children
    • Xiao-Wu W, Herndon DN, Spies M, Sanford AP, Wolf SE (2002) Effects of delayed wound excision and grafting in severely burned children. Arch Surg 137(9): 1049-1054.
    • (2002) Arch Surg , vol.137 , Issue.9 , pp. 1049-1054
    • Xiao-Wu, W.1    Herndon, D.N.2    Spies, M.3    Sanford, A.P.4    Wolf, S.E.5
  • 10
    • 70349659715 scopus 로고    scopus 로고
    • Randomized controlled trial to determine the efficacy of long-term growth hormone treatment in severely burned children
    • Branski LK, Herndon DN, Barrow RE, Kulp GA, Klein GL, et al. (2009) Randomized Controlled Trial to Determine the Efficacy of Long-Term Growth Hormone Treatment in Severely Burned Children. Ann Surg.
    • (2009) Ann Surg
    • Branski, L.K.1    Herndon, D.N.2    Barrow, R.E.3    Kulp, G.A.4    Klein, G.L.5
  • 11
    • 28444479519 scopus 로고    scopus 로고
    • The pharmacologic modulation of the hypermetabolic response to burns
    • Pereira CT, Herndon DN (2005) The pharmacologic modulation of the hypermetabolic response to burns. Adv Surg 39: 245-261.
    • (2005) Adv Surg , vol.39 , pp. 245-261
    • Pereira, C.T.1    Herndon, D.N.2
  • 12
    • 0035136916 scopus 로고    scopus 로고
    • An evaluation of risk factors for mortality after burn trauma and the identification of gender-dependent differences in outcomes
    • O'Keefe GE, Hunt JL, Purdue GF (2001) An evaluation of risk factors for mortality after burn trauma and the identification of gender-dependent differences in outcomes. J Am Coll Surg 192(2): 153-160.
    • (2001) J Am Coll Surg , vol.192 , Issue.2 , pp. 153-160
    • O'Keefe, G.E.1    Hunt, J.L.2    Purdue, G.F.3
  • 13
    • 77951626778 scopus 로고    scopus 로고
    • The leading causes of death after burn injury in a single pediatric burn center
    • Williams FN, Herndon DN, Hawkins HK, Lee JO, Cox RA, et al. (2009) The leading causes of death after burn injury in a single pediatric burn center. Crit Care 13(6): R183.
    • (2009) Crit Care , vol.13 , Issue.6 , pp. 183
    • Williams, F.N.1    Herndon, D.N.2    Hawkins, H.K.3    Lee, J.O.4    Cox, R.A.5
  • 14
    • 85058906292 scopus 로고    scopus 로고
    • Contribution of bacterial and viral infections to attributable mortality in patients with severe burns: An autopsy series
    • D'Avignon LC, Hogan BK, Murray CK, Loo FL, Hospenthal DR, et al. Contribution of bacterial and viral infections to attributable mortality in patients with severe burns: An autopsy series. Burns.
    • Burns
    • D'avignon, L.C.1    Hogan, B.K.2    Murray, C.K.3    Loo, F.L.4    Hospenthal, D.R.5
  • 15
    • 36048998446 scopus 로고    scopus 로고
    • American Burn Association consensus conference to define sepsis and infection in burns
    • Greenhalgh DG, Saffle JR, Holmes JH, 4th, Gamelli RL, Palmieri TL, et al. (2007) American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res 28(6): 776-790.
    • (2007) J Burn Care Res , vol.28 , Issue.6 , pp. 776-790
    • Greenhalgh, D.G.1    Saffle, J.R.2    Holmes, J.H.3    Gamelli, R.L.4    Palmieri, T.L.5
  • 16
    • 0016203896 scopus 로고
    • Evaluation of leukocyte chemotaxis in vitro in thermally injured patients
    • Warden GD, Mason AD, Jr., Pruitt BA, Jr. (1974) Evaluation of leukocyte chemotaxis in vitro in thermally injured patients. J Clin Invest 54(4): 1001-1004.
    • (1974) J Clin Invest , vol.54 , Issue.4 , pp. 1001-1004
    • Warden, G.D.1    Mason Jr., A.D.2    Pruitt Jr., B.A.3
  • 17
    • 0016794452 scopus 로고
    • Suppression of leukocyte chemotaxis in vitro by chemotherapeutic agents used in the management of thermal injuries
    • Warden GD, Mason AD, Jr., Pruitt BA, Jr. (1975) Suppression of leukocyte chemotaxis in vitro by chemotherapeutic agents used in the management of thermal injuries. Ann Surg 181(3): 363-369.
    • (1975) Ann Surg , vol.181 , Issue.3 , pp. 363-369
    • Warden, G.D.1    Mason Jr., A.D.2    Pruitt Jr., B.A.3
  • 18
    • 0024549840 scopus 로고
    • Polymorphonuclear leucocyte motility in patients with severe burns
    • Kim Y, Goldstein E, Lippert W, Brofeldt T, Donovan R (1989) Polymorphonuclear leucocyte motility in patients with severe burns. Burns 15(2): 93-97.
    • (1989) Burns , vol.15 , Issue.2 , pp. 93-97
    • Kim, Y.1    Goldstein, E.2    Lippert, W.3    Brofeldt, T.4    Donovan, R.5
  • 19
    • 0027318146 scopus 로고
    • Down-regulation of chemotaxis of polymorphonuclear leukocytes following thermal injury involves two distinct mechanisms
    • Bjornson AB, Somers SD (1993) Down-regulation of chemotaxis of polymorphonuclear leukocytes following thermal injury involves two distinct mechanisms. J Infect Dis 168(1): 120-127.
    • (1993) J Infect Dis , vol.168 , Issue.1 , pp. 120-127
    • Bjornson, A.B.1    Somers, S.D.2
  • 20
    • 0027193862 scopus 로고
    • Thermal injury, the inflammatory process, and wound dressing reduce human neutrophil chemotaxis to four attractants
    • Hasslen SR, Nelson RD, Ahrenholz DH, Solem LD (1993) Thermal injury, the inflammatory process, and wound dressing reduce human neutrophil chemotaxis to four attractants. J Burn Care Rehabil 14(3): 303-309.
    • (1993) J Burn Care Rehabil , vol.14 , Issue.3 , pp. 303-309
    • Hasslen, S.R.1    Nelson, R.D.2    Ahrenholz, D.H.3    Solem, L.D.4
  • 21
    • 0022613474 scopus 로고
    • Lack of correlation between decreased chemotaxis and susceptibility to infection in burned rats
    • Manktelow A, Meyer AA (1986) Lack of correlation between decreased chemotaxis and susceptibility to infection in burned rats. J Trauma 26(2): 143-148.
    • (1986) J Trauma , vol.26 , Issue.2 , pp. 143-148
    • Manktelow, A.1    Meyer, A.A.2
  • 22
    • 0021691212 scopus 로고
    • Regulation of neutrophil migratory function in burn injury by complement activation products
    • Solomkin JS, Nelson RD, Chenoweth DE, Solem LD, Simmons RL (1984) Regulation of neutrophil migratory function in burn injury by complement activation products. Ann Surg 200(6): 742-746.
    • (1984) Ann Surg , vol.200 , Issue.6 , pp. 742-746
    • Solomkin, J.S.1    Nelson, R.D.2    Chenoweth, D.E.3    Solem, L.D.4    Simmons, R.L.5
  • 23
    • 0034782770 scopus 로고    scopus 로고
    • Early trauma polymorphonuclear neutrophil responses to chemokines are associated with development of sepsis, pneumonia, and organ failure
    • Discussion 456-457
    • Adams JM, Hauser CJ, Livingston DH, Lavery RF, Fekete Z, et al. (2001) Early trauma polymorphonuclear neutrophil responses to chemokines are associated with development of sepsis, pneumonia, and organ failure. J Trauma 51(3): 452-456; discussion 456-457.
    • (2001) J Trauma , vol.51 , Issue.3 , pp. 452-456
    • Adams, J.M.1    Hauser, C.J.2    Livingston, D.H.3    Lavery, R.F.4    Fekete, Z.5
  • 24
    • 0025096671 scopus 로고
    • Altered neutrophil functions in patients with large burns
    • Discussion 142-123
    • Bjerknes R, Vindenes H, Laerum OD (1990) Altered neutrophil functions in patients with large burns. Blood Cells 16(1): 127-141; discussion 142-123.
    • (1990) Blood Cells , vol.16 , Issue.1 , pp. 127-141
    • Bjerknes, R.1    Vindenes, H.2    Laerum, O.D.3
  • 25
    • 0025248064 scopus 로고
    • Effect of local and systemic burn microenvironment on neutrophil activation as assessed by complement receptor expression and morphology
    • Deitch EA, Lu Q, Xu DZ, Specian RD (1990) Effect of local and systemic burn microenvironment on neutrophil activation as assessed by complement receptor expression and morphology. J Trauma 30(3): 259-268.
    • (1990) J Trauma , vol.30 , Issue.3 , pp. 259-268
    • Deitch, E.A.1    Lu, Q.2    Xu, D.Z.3    Specian, R.D.4
  • 26
    • 0022585552 scopus 로고
    • Neutrophil activation in thermal injury as assessed by increased expression of complement receptors
    • Moore FD, Jr., Davis C, Rodrick M, Mannick JA, Fearon DT (1986) Neutrophil activation in thermal injury as assessed by increased expression of complement receptors. N Engl J Med 314(15): 948-953.
    • (1986) N Engl J Med , vol.314 , Issue.15 , pp. 948-953
    • Moore Jr., F.D.1    Davis, C.2    Rodrick, M.3    Mannick, J.A.4    Fearon, D.T.5
  • 28
    • 0027931232 scopus 로고
    • Interference with the function of leukocyte adhesion molecules by monoclonal antibodies: A new approach to burn injury
    • Mileski WJ, Rothlien R, Lipsky P (1994) Interference with the function of leukocyte adhesion molecules by monoclonal antibodies: a new approach to burn injury. Eur J Pediatr Surg 4(4): 225-230.
    • (1994) Eur J Pediatr Surg , vol.4 , Issue.4 , pp. 225-230
    • Mileski, W.J.1    Rothlien, R.2    Lipsky, P.3
  • 29
    • 0027521567 scopus 로고
    • Inhibition of leukocyte adherence in a rabbit model of major thermal injury
    • Mileski W, Gates B, Sigman A, Sikes P, Atiles L, et al. (1993) Inhibition of leukocyte adherence in a rabbit model of major thermal injury. J Burn Care Rehabil 14(6): 610-616.
    • (1993) J Burn Care Rehabil , vol.14 , Issue.6 , pp. 610-616
    • Mileski, W.1    Gates, B.2    Sigman, A.3    Sikes, P.4    Atiles, L.5
  • 30
    • 0025062399 scopus 로고
    • Flow cytometric analysis of neutrophil subsets in thermally injured patients developing infection
    • Babcock GF, Alexander JW, Warden GD (1990) Flow cytometric analysis of neutrophil subsets in thermally injured patients developing infection. Clin Immunol Immunopathol 54(1): 117-125.
    • (1990) Clin Immunol Immunopathol , vol.54 , Issue.1 , pp. 117-125
    • Babcock, G.F.1    Alexander, J.W.2    Warden, G.D.3
  • 31
    • 0025677178 scopus 로고
    • Neutrophil disorders in burn injury: Complement, cytokines, and organ injury
    • Solomkin JS (1990) Neutrophil disorders in burn injury: complement, cytokines, and organ injury. J Trauma 30(12 Suppl): S80-85.
    • (1990) J Trauma , vol.30 , Issue.12 SUPPL. , pp. 80-85
    • Solomkin, J.S.1
  • 32
    • 0027162431 scopus 로고
    • Inhibition of leukocyte adherence and susceptibility to infection
    • Mileski WJ, Sikes P, Atiles L, Lightfoot E, Lipsky P, et al. (1993) Inhibition of leukocyte adherence and susceptibility to infection. J Surg Res 54(4): 349-354.
    • (1993) J Surg Res , vol.54 , Issue.4 , pp. 349-354
    • Mileski, W.J.1    Sikes, P.2    Atiles, L.3    Lightfoot, E.4    Lipsky, P.5
  • 33
    • 0017711309 scopus 로고
    • Neutrophil leucocyte functions and wound bacteria in burn patients
    • Ransjo U, Forsgren A, Arturson G (1977) Neutrophil leucocyte functions and wound bacteria in burn patients. Burns 3(3): 171-178.
    • (1977) Burns , vol.3 , Issue.3 , pp. 171-178
    • Ransjo, U.1    Forsgren, A.2    Arturson, G.3
  • 34
    • 33846932778 scopus 로고    scopus 로고
    • A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects
    • Cheng X, Irimia D, Dixon M, Sekine K, Demirci U, et al. (2007) A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects. Lab Chip 7(2): 170-178.
    • (2007) Lab Chip , vol.7 , Issue.2 , pp. 170-178
    • Cheng, X.1    Irimia, D.2    Dixon, M.3    Sekine, K.4    Demirci, U.5
  • 35
    • 43449103648 scopus 로고    scopus 로고
    • Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients
    • Russom A, Sethu P, Irimia D, Mindrinos MN, Calvano SE, et al. (2008) Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem 54(5): 891-900.
    • (2008) Clin Chem , vol.54 , Issue.5 , pp. 891-900
    • Russom, A.1    Sethu, P.2    Irimia, D.3    Mindrinos, M.N.4    Calvano, S.E.5
  • 36
    • 37549002543 scopus 로고    scopus 로고
    • Isolation of rare circulating tumour cells in cancer patients by microchip technology
    • Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, et al. (2007) Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450(7173): 1235-1239.
    • (2007) Nature , vol.450 , Issue.7173 , pp. 1235-1239
    • Nagrath, S.1    Sequist, L.V.2    Maheswaran, S.3    Bell, D.W.4    Irimia, D.5
  • 37
    • 0036022527 scopus 로고    scopus 로고
    • Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device
    • Li Jeon N, Baskaran H, Dertinger SK, Whitesides GM, Van de Water L, et al. (2002) Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat Biotechnol 20(8): 826-830.
    • (2002) Nat Biotechnol , vol.20 , Issue.8 , pp. 826-830
    • Li, J.N.1    Baskaran, H.2    Dertinger, S.K.3    Whitesides, G.M.4    Van De, W.L.5
  • 38
    • 18244384464 scopus 로고    scopus 로고
    • Neutrophil migration in opposing chemoattractant gradients using microfluidic chemotaxis devices
    • Lin F, Nguyen CM, Wang SJ, Saadi W, Gross SP, et al. (2005) Neutrophil migration in opposing chemoattractant gradients using microfluidic chemotaxis devices. Ann Biomed Eng 33(4): 475-482.
    • (2005) Ann Biomed Eng , vol.33 , Issue.4 , pp. 475-482
    • Lin, F.1    Nguyen, C.M.2    Wang, S.J.3    Saadi, W.4    Gross, S.P.5
  • 39
    • 33645383666 scopus 로고    scopus 로고
    • Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients
    • Irimia D, Liu SY, Tharp WG, Samadani A, Toner M, et al. (2006) Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip 6(2): 191-198.
    • (2006) Lab Chip , vol.6 , Issue.2 , pp. 191-198
    • Irimia, D.1    Liu, S.Y.2    Tharp, W.G.3    Samadani, A.4    Toner, M.5
  • 40
    • 33745486504 scopus 로고    scopus 로고
    • Measurement of cell migration in response to an evolving radial chemokine gradient triggered by a microvalve
    • Frevert CW, Boggy G, Keenan TM, Folch A (2006) Measurement of cell migration in response to an evolving radial chemokine gradient triggered by a microvalve. Lab Chip 6(7): 849-856.
    • (2006) Lab Chip , vol.6 , Issue.7 , pp. 849-856
    • Frevert, C.W.1    Boggy, G.2    Keenan, T.M.3    Folch, A.4
  • 41
    • 52649140667 scopus 로고    scopus 로고
    • A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment
    • Abhyankar VV, Toepke MW, Cortesio CL, Lokuta MA, Huttenlocher A, et al. (2008) A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment. Lab Chip 8(9): 1507-1515.
    • (2008) Lab Chip , vol.8 , Issue.9 , pp. 1507-1515
    • Abhyankar, V.V.1    Toepke, M.W.2    Cortesio, C.L.3    Lokuta, M.A.4    Huttenlocher, A.5
  • 42
    • 33646090415 scopus 로고    scopus 로고
    • Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo
    • Tharp WG, Yadav R, Irimia D, Upadhyaya A, Samadani A, et al. (2006) Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo. J Leukoc Biol 79(3): 539-554.
    • (2006) J Leukoc Biol , vol.79 , Issue.3 , pp. 539-554
    • Tharp, W.G.1    Yadav, R.2    Irimia, D.3    Upadhyaya, A.4    Samadani, A.5
  • 43
    • 56549124915 scopus 로고    scopus 로고
    • Neutrophil migration assay from a drop of blood
    • Agrawal N, Toner M, Irimia D (2008) Neutrophil migration assay from a drop of blood. Lab Chip 8(12): 2054-2061.
    • (2008) Lab Chip , vol.8 , Issue.12 , pp. 2054-2061
    • Agrawal, N.1    Toner, M.2    Irimia, D.3
  • 44
    • 58849111789 scopus 로고    scopus 로고
    • Rapid appearance of resolvin precursors in inflammatory exudates: Novel mechanisms in resolution
    • Kasuga K, Yang R, Porter TF, Agrawal N, Petasis NA, et al. (2008) Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J Immunol 181(12): 8677-8687.
    • (2008) J Immunol , vol.181 , Issue.12 , pp. 8677-8687
    • Kasuga, K.1    Yang, R.2    Porter, T.F.3    Agrawal, N.4    Petasis, N.A.5
  • 45
    • 0343841187 scopus 로고
    • The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes
    • Boyden S (1962) The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. J Exp Med 115: 453-466.
    • (1962) J Exp Med , vol.115 , pp. 453-466
    • Boyden, S.1
  • 46
    • 0017660115 scopus 로고
    • Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors
    • Zigmond SH (1977) Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors. J Cell Biol 75(2 Pt 1): 606-616.
    • (1977) J Cell Biol , vol.75 , Issue.2 PART 1 , pp. 606-616
    • Zigmond, S.H.1
  • 47
    • 0025788971 scopus 로고
    • A new direct-viewing chemotaxis chamber
    • Zicha D, Dunn GA, Brown AF (1991) A new direct-viewing chemotaxis chamber. J Cell Sci 99 (Pt 4): 769-775.
    • (1991) J Cell Sci , vol.99 , Issue.PART 4 , pp. 769-775
    • Zicha, D.1    Dunn, G.A.2    Brown, A.F.3
  • 48
    • 33644659211 scopus 로고    scopus 로고
    • Characterization of a membrane-based gradient generator for use in cell-signaling studies
    • Abhyankar VV, Lokuta MA, Huttenlocher A, Beebe DJ (2006) Characterization of a membrane-based gradient generator for use in cell-signaling studies. Lab Chip 6(3): 389-393.
    • (2006) Lab Chip , vol.6 , Issue.3 , pp. 389-393
    • Abhyankar, V.V.1    Lokuta, M.A.2    Huttenlocher, A.3    Beebe, D.J.4
  • 49
    • 0019731437 scopus 로고
    • Chemotactic reorientation of granulocytes stimulated with micropipettes containing fMet-Leu-Phe
    • Gerisch G, Keller HU (1981) Chemotactic reorientation of granulocytes stimulated with micropipettes containing fMet-Leu-Phe. J Cell Sci 52: 1-10.
    • (1981) J Cell Sci , vol.52 , pp. 1-10
    • Gerisch, G.1    Keller, H.U.2
  • 50
    • 2642585585 scopus 로고    scopus 로고
    • Effective neutrophil chemotaxis is strongly influenced by mean IL-8 concentration
    • Lin F, Nguyen CM, Wang SJ, Saadi W, Gross SP, et al. (2004) Effective neutrophil chemotaxis is strongly influenced by mean IL-8 concentration. Biochem Biophys Res Commun 319(2): 576-581.
    • (2004) Biochem Biophys Res Commun , vol.319 , Issue.2 , pp. 576-581
    • Lin, F.1    Nguyen, C.M.2    Wang, S.J.3    Saadi, W.4    Gross, S.P.5
  • 51
    • 20844440162 scopus 로고    scopus 로고
    • Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator
    • Walker GM, Sai J, Richmond A, Stremler M, Chung CY, et al. (2005) Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator. Lab Chip 5(6): 611-618.
    • (2005) Lab Chip , vol.5 , Issue.6 , pp. 611-618
    • Walker, G.M.1    Sai, J.2    Richmond, A.3    Stremler, M.4    Chung, C.Y.5
  • 52
    • 0027944293 scopus 로고
    • The fundamental motor of the human neutrophil is not random: Evidence for local non-Markov movement in neutrophils
    • Hartman RS, Lau K, Chou W, Coates TD (1994) The fundamental motor of the human neutrophil is not random: evidence for local non-Markov movement in neutrophils. Biophys J 67(6): 2535-2545.
    • (1994) Biophys J , vol.67 , Issue.6 , pp. 2535-2545
    • Hartman, R.S.1    Lau, K.2    Chou, W.3    Coates, T.D.4
  • 53
    • 36348989555 scopus 로고    scopus 로고
    • Polar stimulation and constrained cell migration in microfluidic channels
    • Irimia D, Charras G, Agrawal N, Mitchison T, Toner M (2007) Polar stimulation and constrained cell migration in microfluidic channels. Lab Chip 7(12): 1783-1790.
    • (2007) Lab Chip , vol.7 , Issue.12 , pp. 1783-1790
    • Irimia, D.1    Charras, G.2    Agrawal, N.3    Mitchison, T.4    Toner, M.5
  • 54
    • 0030881883 scopus 로고    scopus 로고
    • Random locomotion and chemotaxis of human blood polymorphonuclear leukocytes (PMN) in the presence of EDTA: PMN in close quarters require neither leukocyte integrins nor external divalent cations
    • Malawista SE, de Boisfleury Chevance A (1997) Random locomotion and chemotaxis of human blood polymorphonuclear leukocytes (PMN) in the presence of EDTA: PMN in close quarters require neither leukocyte integrins nor external divalent cations. Proc Natl Acad Sci U S A 94(21): 11577-11582.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.21 , pp. 11577-11582
    • Malawista, S.E.1    de, B.C.A.2
  • 55
    • 0028146952 scopus 로고
    • Cytoskeletal actin: The influence of major burns on neutrophil structure and function
    • de Chalain TM, Bracher M, Linley W, Gerneke D, Hickman R (1994) Cytoskeletal actin: the influence of major burns on neutrophil structure and function. Burns 20(5): 416-421.
    • (1994) Burns , vol.20 , Issue.5 , pp. 416-421
    • de, C.T.M.1    Bracher, M.2    Linley, W.3    Gerneke, D.4    Hickman, R.5
  • 56
    • 33751236488 scopus 로고    scopus 로고
    • New developments in fluid resuscitation
    • Alam HB, Rhee P (2007) New developments in fluid resuscitation. Surg Clin North Am 87(1): 55-72, vi.
    • (2007) Surg Clin North Am , vol.87 , Issue.1 , pp. 55-72
    • Alam, H.B.1    Rhee, P.2
  • 57
    • 0038002722 scopus 로고    scopus 로고
    • Allogeneic blood transfusion increases the risk of postoperative bacterial infection: A metaanalysis
    • Hill GE, Frawley WH, Griffith KE, Forestner JE, Minei JP (2003) Allogeneic blood transfusion increases the risk of postoperative bacterial infection: a metaanalysis. J Trauma 54(5): 908-914.
    • (2003) J Trauma , vol.54 , Issue.5 , pp. 908-914
    • Hill, G.E.1    Frawley, W.H.2    Griffith, K.E.3    Forestner, J.E.4    Minei, J.P.5
  • 58
    • 34447542644 scopus 로고    scopus 로고
    • Evaluation of white blood cell count, neutrophil percentage, and elevated temperature as predictors of bloodstream infection in burn patients
    • Murray CK, Hoffmaster RM, Schmit DR, Hospenthal DR, Ward JA, et al. (2007) Evaluation of white blood cell count, neutrophil percentage, and elevated temperature as predictors of bloodstream infection in burn patients. Arch Surg 142(7): 639-642.
    • (2007) Arch Surg , vol.142 , Issue.7 , pp. 639-642
    • Murray, C.K.1    Hoffmaster, R.M.2    Schmit, D.R.3    Hospenthal, D.R.4    Ward, J.A.5
  • 59
    • 0035166624 scopus 로고    scopus 로고
    • Neutrophil disorders and their management
    • Lakshman R, Finn A (2001) Neutrophil disorders and their management. J Clin Pathol 54(1): 7-19.
    • (2001) J Clin Pathol , vol.54 , Issue.1 , pp. 7-19
    • Lakshman, R.1    Finn, A.2
  • 60
    • 0016712881 scopus 로고
    • Chemotaxis under agarose: A new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leukocytes and monocytes
    • Nelson RD, Quie PG, Simmons RL (1975) Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leukocytes and monocytes. J Immunol 115(6): 1650-1656.
    • (1975) J Immunol , vol.115 , Issue.6 , pp. 1650-1656
    • Nelson, R.D.1    Quie, P.G.2    Simmons, R.L.3
  • 61
    • 47749127419 scopus 로고    scopus 로고
    • Microfluidic switching system for analyzing chemotaxis responses of wortmannin-inhibited HL-60 cells
    • Liu Y, Sai J, Richmond A, Wikswo JP (2008) Microfluidic switching system for analyzing chemotaxis responses of wortmannin-inhibited HL-60 cells. Biomed Microdevices 10(4): 499-507.
    • (2008) Biomed Microdevices , vol.10 , Issue.4 , pp. 499-507
    • Liu, Y.1    Sai, J.2    Richmond, A.3    Wikswo, J.P.4
  • 62
    • 34249810035 scopus 로고    scopus 로고
    • A hydrogel-based microfluidic device for the studies of directed cell migration
    • Cheng SY, Heilman S, Wasserman M, Archer S, Shuler ML, et al. (2007) A hydrogel-based microfluidic device for the studies of directed cell migration. Lab Chip 7(6): 763-769.
    • (2007) Lab Chip , vol.7 , Issue.6 , pp. 763-769
    • Cheng, S.Y.1    Heilman, S.2    Wasserman, M.3    Archer, S.4    Shuler, M.L.5
  • 63
    • 67649305243 scopus 로고    scopus 로고
    • Selective and tunable gradient device for cell culture and chemotaxis study
    • Kim D, Lokuta MA, Huttenlocher A, Beebe DJ (2009) Selective and tunable gradient device for cell culture and chemotaxis study. Lab Chip 9(12): 1797-1800.
    • (2009) Lab Chip , vol.9 , Issue.12 , pp. 1797-1800
    • Kim, D.1    Lokuta, M.A.2    Huttenlocher, A.3    Beebe, D.J.4
  • 64
    • 33744911101 scopus 로고    scopus 로고
    • A microfluidic multi-injector for gradient generation
    • Chung BG, Lin F, Jeon NL (2006) A microfluidic multi-injector for gradient generation. Lab Chip 6(6): 764-768.
    • (2006) Lab Chip , vol.6 , Issue.6 , pp. 764-768
    • Chung, B.G.1    Lin, F.2    Jeon, N.L.3
  • 65
    • 34548354876 scopus 로고    scopus 로고
    • Generation of stable concentration gradients in 2D and 3D environments using a microfluidic ladder chamber
    • Saadi W, Rhee SW, Lin F, Vahidi B, Chung BG, et al. (2007) Generation of stable concentration gradients in 2D and 3D environments using a microfluidic ladder chamber. Biomed Microdevices 9(5): 627-635.
    • (2007) Biomed Microdevices , vol.9 , Issue.5 , pp. 627-635
    • Saadi, W.1    Rhee, S.W.2    Lin, F.3    Vahidi, B.4    Chung, B.G.5
  • 66
    • 77951912747 scopus 로고    scopus 로고
    • A new method for studying gradient-induced neutrophil desensitization based on an open microfluidic chamber
    • Keenan TM, Frevert CW, Wu A, Wong V, Folch A (2010) A new method for studying gradient-induced neutrophil desensitization based on an open microfluidic chamber. Lab Chip 10(1): 116-122.
    • (2010) Lab Chip , vol.10 , Issue.1 , pp. 116-122
    • Keenan, T.M.1    Frevert, C.W.2    Wu, A.3    Wong, V.4    Folch, A.5


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