메뉴 건너뛰기




Volumn 81, Issue , 2014, Pages 256-266

GSK-3/CREB pathway involved in the gx-50's effect on Alzheimer's disease

Author keywords

Alzheimer's disease; cAMP response element binding protein; Glycogen synthase kinase 3; gx 50; Microarray analysis

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3; GX 50; N [2 (3, 4 DIMETHOXYPHENYL)ETHYL] 3 PHENYL ACRYLAMIDE; NEUROPROTECTIVE AGENT; OLIGOMER; PROTEIN KINASE B; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; AMYLOID PRECURSOR PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; N-(2-(3,4-DIMETHOXYPHENYL)ETHYL)-3-PHENYL-ACRYLAMIDE; NERVE PROTEIN; NEUROLEPTIC AGENT;

EID: 84896131461     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.02.008     Document Type: Article
Times cited : (25)

References (57)
  • 1
    • 69549138878 scopus 로고    scopus 로고
    • Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease
    • T. Abbas, E. Faivre, and C. Hölscher Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease Behav. Brain Res. 205 2009 265 271
    • (2009) Behav. Brain Res. , vol.205 , pp. 265-271
    • Abbas, T.1    Faivre, E.2    Hölscher, C.3
  • 2
    • 52449089987 scopus 로고    scopus 로고
    • Thirty years of Alzheimer's disease genetics: The implications of systematic meta-analyses
    • L. Bertram, and R.E. Tanzi Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses Nat. Rev. Neurosci. 9 2008 768 778
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 768-778
    • Bertram, L.1    Tanzi, R.E.2
  • 3
    • 84857063922 scopus 로고    scopus 로고
    • Cyclic AMP response element-binding protein (CREB) phosphorylation: A mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics
    • R.S. Bitner Cyclic AMP response element-binding protein (CREB) phosphorylation: a mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics Biochem. Pharmacol. 83 2012 705 714
    • (2012) Biochem. Pharmacol. , vol.83 , pp. 705-714
    • Bitner, R.S.1
  • 4
    • 34249697099 scopus 로고    scopus 로고
    • Forecasting the global burden of Alzheimer's disease
    • DOI 10.1016/j.jalz.2007.04.381, PII S155252600700475X
    • R. Brookmeyer, E. Johnson, K. Ziegler-Graham, and H.M. Arrighi Forecasting the global burden of Alzheimer's disease Alzheimers Dement. 3 2007 186 191 (Pubitemid 46825511)
    • (2007) Alzheimer's and Dementia , vol.3 , Issue.3 , pp. 186-191
    • Brookmeyer, R.1    Johnson, E.2    Ziegler-Graham, K.3    Arrighi, H.M.4
  • 5
    • 84984932472 scopus 로고    scopus 로고
    • Exploring the new world of the genome with DNA microarrays
    • DOI 10.1038/4462
    • P.O. Brown, and D. Botstein Exploring the new world of the genome with DNA microarrays Nat. Genet. 21 1999 33 37 (Pubitemid 29031489)
    • (1999) Nature Genetics , vol.21 , Issue.1 SUPPL. , pp. 33-37
    • Brown, P.O.1    Botstein, D.2
  • 6
    • 0036255542 scopus 로고    scopus 로고
    • The mouse: Genetics meets behaviour
    • DOI 10.1038/nrg728
    • M. Bućan, and T. Abel The mouse: genetics meets behaviour Nat. Rev. Genet. 3 2002 114 123 (Pubitemid 34506595)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.2 , pp. 114-123
    • Bucan, M.1    Abel, T.2
  • 7
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • D.A.E. Cross, D.R. Alessi, P. Cohen, M. Andjelkovich, and B.A. Hemmings Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B Nature 378 1995 785 789 (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 8
    • 0033994012 scopus 로고    scopus 로고
    • Calcium-regulated protein kinase cascades and their transcription factor targets
    • F.H. Cruzalegui, and H. Bading Calcium-regulated protein kinase cascades and their transcription factor targets Cell. Mol. Life Sci. 57 2000 402 410 (Pubitemid 30223567)
    • (2000) Cellular and Molecular Life Sciences , vol.57 , Issue.3 , pp. 402-410
    • Cruzalegui, F.H.1    Bading, H.2
  • 9
    • 81955167913 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease
    • B. DaRocha-Souto, M. Coma, B.G. Pérez-Nievas, T.C. Scotton, M. Siao, and P. Sánchez-Ferrer et al. Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease Neurobiol. Dis. 45 2012 425 437
    • (2012) Neurobiol. Dis. , vol.45 , pp. 425-437
    • Darocha-Souto, B.1    Coma, M.2    Pérez-Nievas, B.G.3    Scotton, T.C.4    Siao, M.5    Sánchez-Ferrer, P.6
  • 10
    • 80053940832 scopus 로고    scopus 로고
    • Melatonin as a central molecule connecting neural development and calcium signaling
    • J. De Faria Poloni, B.C. Feltes, and D. Bonatto Melatonin as a central molecule connecting neural development and calcium signaling Funct. Integr. Genomics 11 2011 383 388
    • (2011) Funct. Integr. Genomics , vol.11 , pp. 383-388
    • De Faria Poloni, J.1    Feltes, B.C.2    Bonatto, D.3
  • 11
    • 0033850796 scopus 로고    scopus 로고
    • Wnt signaling function in Alzheimer's disease
    • G.V. De Ferrari, and N.C. Inestrosa Wnt signaling function in Alzheimer's disease Brain Res. Rev. 33 2000 1 12
    • (2000) Brain Res. Rev. , vol.33 , pp. 1-12
    • De Ferrari, G.V.1    Inestrosa, N.C.2
  • 12
    • 77951060145 scopus 로고    scopus 로고
    • Proteases and proteolysis in Alzheimer disease: A multifactorial view on the disease process
    • B. De Strooper Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process Physiol. Rev. 90 2010 465 494
    • (2010) Physiol. Rev. , vol.90 , pp. 465-494
    • De Strooper, B.1
  • 13
    • 0030059338 scopus 로고    scopus 로고
    • Signaling from synapse to nucleus: Postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity
    • DOI 10.1016/S0896-6273(00)80026-4
    • K. Deisseroth, H. Bito, and R.W. Tsien Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity Neuron 16 1996 89 101 (Pubitemid 26044732)
    • (1996) Neuron , vol.16 , Issue.1 , pp. 89-101
    • Deisseroth, K.1    Bito, H.2    Tsien, R.W.3
  • 15
    • 0027092647 scopus 로고
    • Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
    • S.G.N. Grant, T.J. O'Dell, K.A. Karl, P.L. Stein, P. Soriano, and E.R. Kandel Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice Science 258 1992 1903 1910 (Pubitemid 23026728)
    • (1992) Science , vol.258 , Issue.5090 , pp. 1903-1910
    • Grant, S.G.N.1    O'Dell, T.J.2    Karl, K.A.3    Stein, P.L.4    Soriano, P.5    Kandel, E.R.6
  • 16
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • D. Harold, R. Abraham, P. Hollingworth, R. Sims, A. Gerrish, and M.L. Hamshere et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nat. Genet. 41 2009 1088 1093
    • (2009) Nat. Genet. , vol.41 , pp. 1088-1093
    • Harold, D.1    Abraham, R.2    Hollingworth, P.3    Sims, R.4    Gerrish, A.5    Hamshere, M.L.6
  • 17
    • 0037451782 scopus 로고    scopus 로고
    • Lithium stimulates progenitor proliferation in cultured brain neurons
    • DOI 10.1016/S0306-4522(02)00577-8
    • R. Hashimoto, V. Senatorov, H. Kanai, P. Leeds, and D.M. Chuang Lithium stimulates progenitor proliferation in cultured brain neurons Neuroscience 117 2003 55 61 (Pubitemid 36246503)
    • (2003) Neuroscience , vol.117 , Issue.1 , pp. 55-61
    • Hashimoto, R.1    Senatorov, V.2    Kanai, H.3    Leeds, P.4    Chuang, D.-M.5
  • 19
    • 1642363745 scopus 로고    scopus 로고
    • Spatial learning deficit in transgenic mice that conditionally over-express GSK-3β in the brain but do not form tau filaments
    • DOI 10.1046/j.1471-4159.2002.01269.x
    • F. Hernández, J. Borrell, C. Guaza, J. Avila, and J.J. Lucas Spatial learning deficit in transgenic mice that conditionally over-express GSK-3β in the brain but do not form tau filaments J. Neurochem. 83 2002 1529 1533 (Pubitemid 35477491)
    • (2002) Journal of Neurochemistry , vol.83 , Issue.6 , pp. 1529-1533
    • Hernandez, F.1    Borrell, J.2    Guaza, C.3    Avila, J.4    Lucas, J.J.5
  • 21
    • 77954874401 scopus 로고    scopus 로고
    • GSK3 signalling in neural development
    • E.M. Hur, and F.Q. Zhou GSK3 signalling in neural development Nat. Rev. Neurosci. 11 2010 539 551
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 539-551
    • Hur, E.M.1    Zhou, F.Q.2
  • 24
    • 79956320988 scopus 로고    scopus 로고
    • Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mouse model
    • S. Jimenez, M. Torres, M. Vizuete, R. Sanchez-Varo, E. Sanchez-Mejias, and L. Trujillo-Estrada et al. Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mouse model J. Biol. Chem. 286 2011 18414 18425
    • (2011) J. Biol. Chem. , vol.286 , pp. 18414-18425
    • Jimenez, S.1    Torres, M.2    Vizuete, M.3    Sanchez-Varo, R.4    Sanchez-Mejias, E.5    Trujillo-Estrada, L.6
  • 25
    • 77958507752 scopus 로고    scopus 로고
    • The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: Clinical report and quantification of Aβ in different brain regions
    • L. Keller, H. Welander, H.H. Chiang, L.O. Tjernberg, I. Nennesmo, and A.K. Wallin et al. The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of Aβ in different brain regions Eur. J. Hum. Genet. 18 2010 1202 1208
    • (2010) Eur. J. Hum. Genet. , vol.18 , pp. 1202-1208
    • Keller, L.1    Welander, H.2    Chiang, H.H.3    Tjernberg, L.O.4    Nennesmo, I.5    Wallin, A.K.6
  • 27
    • 33748632656 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor mechanisms and function in adult synaptic plasticity: New insights and implications for therapy
    • S.D. Kuipers, and C.R. Bramham Brain-derived neurotrophic factor mechanisms and function in adult synaptic plasticity: new insights and implications for therapy Curr. Opin. Drug Disc. Dev. 9 2006 580 586 (Pubitemid 44378826)
    • (2006) Current Opinion in Drug Discovery and Development , vol.9 , Issue.5 , pp. 580-586
    • Kuipers, S.D.1    Bramham, C.R.2
  • 28
    • 3042514191 scopus 로고    scopus 로고
    • Coexpresion analysis of human genes across many microarray data sets
    • DOI 10.1101/gr.1910904
    • H.K. Lee, A.K. Hsu, J. Sajdak, J. Qin, and P. Pavlidis Coexpression analysis of human genes across many microarray data sets Genome Res. 14 2004 1085 1094 (Pubitemid 38811545)
    • (2004) Genome Research , vol.14 , Issue.6 , pp. 1085-1094
    • Lee, H.K.1    Hsu, A.K.2    Sajdak, J.3    Qin, J.4    Pavlidis, P.5
  • 29
    • 0032989714 scopus 로고    scopus 로고
    • Developmental expression and localization of glycogen synthase kinase-3β in rat brain
    • DOI 10.1016/S0891-0618(99)00012-5, PII S0891061899000125
    • K. Leroy, and J.P. Brion Developmental expression and localization of glycogen synthase kinase-3β in rat brain J. Chem. Neuroanat. 16 1999 279 293 (Pubitemid 29296952)
    • (1999) Journal of Chemical Neuroanatomy , vol.16 , Issue.4 , pp. 279-293
    • Leroy, K.1    Brion, J.-P.2
  • 30
    • 84865003170 scopus 로고    scopus 로고
    • Reduction in delayed mortality and subtle improvement in retrograde memory performance in pilocarpine-treated mice with conditional neuronal deletion of cyclooxygenase-2 gene
    • J.R. Levin, G. Serrano, and R. Dingledine Reduction in delayed mortality and subtle improvement in retrograde memory performance in pilocarpine-treated mice with conditional neuronal deletion of cyclooxygenase-2 gene Epilepsia 53 2012 1411 1420
    • (2012) Epilepsia , vol.53 , pp. 1411-1420
    • Levin, J.R.1    Serrano, G.2    Dingledine, R.3
  • 31
    • 0037101970 scopus 로고    scopus 로고
    • Function and regulation of CREB family transcription factors in the nervous system
    • DOI 10.1016/S0896-6273(02)00828-0
    • B.E. Lonze, and D.D. Ginty Function and regulation of CREB family transcription factors in the nervous system Neuron 35 2002 605 623 (Pubitemid 35229980)
    • (2002) Neuron , vol.35 , Issue.4 , pp. 605-623
    • Lonze, B.E.1    Ginty, D.D.2
  • 32
    • 84878227058 scopus 로고    scopus 로고
    • BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases
    • B. Lu, G. Nagappan, X. Guan, P.J. Nathan, and P. Wren BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases Nat. Rev. Neurosci. 14 2013 401 416
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 401-416
    • Lu, B.1    Nagappan, G.2    Guan, X.3    Nathan, P.J.4    Wren, P.5
  • 36
    • 77949532372 scopus 로고    scopus 로고
    • Expression of genes encoding multi-transmembrane proteins in specific primate taste cell populations
    • art. no. e7682
    • B.D. Moyer, P. Hevezi, N. Gao, M. Lu, D. Kalabat, and H. Soto et al. Expression of genes encoding multi-transmembrane proteins in specific primate taste cell populations PLoS One 4 2009 art. no. e7682
    • (2009) PLoS One , vol.4
    • Moyer, B.D.1    Hevezi, P.2    Gao, N.3    Lu, M.4    Kalabat, D.5    Soto, H.6
  • 37
    • 37049036195 scopus 로고    scopus 로고
    • 23-54, and an Aβ-RAGE complex in PC-12 cells
    • DOI 10.2174/156720507783018325
    • S. Mruthinti, N. Capito, A. Sood, and J.J. Buccafusco Cytotoxicity of Aβ1-42, RAGE23-54, and an Aβ-RAGE complex in PC-12 cells Curr. Alzheimer Res. 4 2007 581 586 (Pubitemid 350248397)
    • (2007) Current Alzheimer Research , vol.4 , Issue.5 , pp. 581-586
    • Mruthinti, S.1    Capito, N.2    Sood, A.3    Buccafusco, J.J.4
  • 40
    • 68449089420 scopus 로고    scopus 로고
    • Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's Disease
    • S.G. Potkin, G. Guffanti, A. Lakatos, J.A. Turner, F. Kruggel, and J.H. Fallon et al. Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's Disease PLoS One 4 2009 e6501
    • (2009) PLoS One , vol.4 , pp. 6501
    • Potkin, S.G.1    Guffanti, G.2    Lakatos, A.3    Turner, J.A.4    Kruggel, F.5    Fallon, J.H.6
  • 41
    • 21344435992 scopus 로고    scopus 로고
    • Invariant visual representation by single neurons in the human brain
    • DOI 10.1038/nature03687
    • R.Q. Quiroga, L. Reddy, G. Kreiman, C. Koch, and I. Fried Invariant visual representation by single neurons in the human brain Nature 435 2005 1102 1107 (Pubitemid 40910517)
    • (2005) Nature , vol.435 , Issue.7045 , pp. 1102-1107
    • Quiroga, R.Q.1    Reddy, L.2    Kreiman, G.3    Koch, C.4    Fried, I.5
  • 42
    • 80052638741 scopus 로고    scopus 로고
    • Beneficial effects of a neurotrophic peptidergic mixture persist for a prolonged period following treatment interruption in a transgenic model of Alzheimer's disease
    • E. Rockenstein, K. Ubhi, E. Pham, S. Michael, E. Doppler, and P. Novak et al. Beneficial effects of a neurotrophic peptidergic mixture persist for a prolonged period following treatment interruption in a transgenic model of Alzheimer's disease J. Neurosci. Res. 89 2011 1812 1821
    • (2011) J. Neurosci. Res. , vol.89 , pp. 1812-1821
    • Rockenstein, E.1    Ubhi, K.2    Pham, E.3    Michael, S.4    Doppler, E.5    Novak, P.6
  • 43
    • 0032945651 scopus 로고    scopus 로고
    • Maternal corticotropin-releasing hormone and habituation in the human fetus
    • DOI 10.1002/(SICI)1098-2302(199904)34:3<163::AID-DEV1>3.0.CO;2-9
    • C.A. Sandman, P.D. Wadhwa, A. Chicz-DeMet, M. Porto, and T.J. Garite Maternal corticotropin-releasing hormone and habituation in the human fetus Dev. Psychobiol. 34 1999 163 173 (Pubitemid 29165944)
    • (1999) Developmental Psychobiology , vol.34 , Issue.3 , pp. 163-173
    • Sandman, C.A.1    Wadhwa, P.D.2    Chicz-DeMet, A.3    Porto, M.4    Garite, T.J.5
  • 44
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • M. Schena, D. Shalon, R.W. Davis, and P.O. Brown Quantitative monitoring of gene expression patterns with a complementary DNA microarray Science 270 1995 467 470
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 45
    • 77953061132 scopus 로고    scopus 로고
    • Dorsal hippocampal CREB is both necessary and sufficient for spatial memory
    • M.J. Sekeres, R.L. Neve, P.W. Frankland, and S.A. Josselyn Dorsal hippocampal CREB is both necessary and sufficient for spatial memory Learn. Mem. 17 2005 280 283
    • (2005) Learn. Mem. , vol.17 , pp. 280-283
    • Sekeres, M.J.1    Neve, R.L.2    Frankland, P.W.3    Josselyn, S.A.4
  • 46
    • 77249116152 scopus 로고    scopus 로고
    • Gene expression profiling in the developing rat brain exposed to ketamine
    • Q. Shi, L. Guo, T.A. Patterson, S. Dial, Q. Li, and N. Sadovova et al. Gene expression profiling in the developing rat brain exposed to ketamine Neuroscience 166 2010 852 863
    • (2010) Neuroscience , vol.166 , pp. 852-863
    • Shi, Q.1    Guo, L.2    Patterson, T.A.3    Dial, S.4    Li, Q.5    Sadovova, N.6
  • 47
    • 84858770007 scopus 로고    scopus 로고
    • Old drug, new hope for Alzheimer's disease
    • W.J. Strittmatter Old drug, new hope for Alzheimer's disease Science 335 2012 1447 1448
    • (2012) Science , vol.335 , pp. 1447-1448
    • Strittmatter, W.J.1
  • 48
    • 84874333716 scopus 로고    scopus 로고
    • A novel drug candidate for Alzheimer's disease treatment: Gx-50 derived from Zanthoxylum Bungeanum
    • M. Tang, Z.X. Wang, Y. Zhou, W. Xu, S. Li, and L. Wang et al. A novel drug candidate for Alzheimer's disease treatment: gx-50 derived from Zanthoxylum Bungeanum J. Alzheimers Dis. 34 2013 203 213
    • (2013) J. Alzheimers Dis. , vol.34 , pp. 203-213
    • Tang, M.1    Wang, Z.X.2    Zhou, Y.3    Xu, W.4    Li, S.5    Wang, L.6
  • 49
    • 0036460741 scopus 로고    scopus 로고
    • Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: Implications for stress-related cortical pathology?
    • DOI 10.1046/j.1460-9568.2002.02000.x
    • A. Trentani, S.D. Kuipers, G.J. Ter Horst, and J.A. Den Boer Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: implications for stress-related cortical pathology? Eur. J. Neurosci. 15 2002 1681 1691 (Pubitemid 35471924)
    • (2002) European Journal of Neuroscience , vol.15 , Issue.10 , pp. 1681-1691
    • Trentani, A.1    Kuipers, S.D.2    Ter Horst, G.J.3    Den Boer, J.A.4
  • 50
    • 80053347072 scopus 로고    scopus 로고
    • Expression profiling reveals differential gene induction underlying specific and non-specific memory for pheromones in mice
    • S.C. Upadhya, T.K. Smith, P.A. Brennan, J.C. Mychaleckyj, and A.N. Hegde Expression profiling reveals differential gene induction underlying specific and non-specific memory for pheromones in mice Neurochem. Int. 59 2011 787 803
    • (2011) Neurochem. Int. , vol.59 , pp. 787-803
    • Upadhya, S.C.1    Smith, T.K.2    Brennan, P.A.3    Mychaleckyj, J.C.4    Hegde, A.N.5
  • 51
    • 34250815052 scopus 로고    scopus 로고
    • Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis
    • DOI 10.1523/JNEUROSCI.5564-06.2007
    • L. Verret, J.L. Jankowsky, G.M. Xu, D.R. Borchelt, and C. Rampon Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis J. Neurosci. 27 2007 6771 6780 (Pubitemid 46983445)
    • (2007) Journal of Neuroscience , vol.27 , Issue.25 , pp. 6771-6780
    • Verret, L.1    Jankowsky, J.L.2    Xu, G.M.3    Borchelt, D.R.4    Rampon, C.5
  • 52
    • 37149014221 scopus 로고    scopus 로고
    • Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity
    • DOI 10.1039/b712728f
    • M.R. Wilson, J.J. Yerbury, and S. Poon Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity Mol. Biosyst. 4 2007 42 52 (Pubitemid 350261753)
    • (2007) Molecular BioSystems , vol.4 , Issue.1 , pp. 42-52
    • Wilson, M.R.1    Yerbury, J.J.2    Poon, S.3
  • 54
    • 42549094317 scopus 로고    scopus 로고
    • Gene expression atlas of the mouse central nervous system: Impact and interactions of age, energy intake and gender
    • X. Xu, M. Zhan, W. Duan, V. Prabhu, R. Brenneman, and W. Wood et al. Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender Genome Biol. 8 2007 R234
    • (2007) Genome Biol. , vol.8 , pp. 234
    • Xu, X.1    Zhan, M.2    Duan, W.3    Prabhu, V.4    Brenneman, R.5    Wood, W.6
  • 56
    • 1642464725 scopus 로고    scopus 로고
    • Genistein ameliorates β-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis
    • DOI 10.1016/j.freeradbiomed.2003.10.018
    • H. Zeng, Q. Chen, and B. Zhao Genistein ameliorates β-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis Free Radic. Biol. Med. 36 2004 180 188 (Pubitemid 38117236)
    • (2004) Free Radical Biology and Medicine , vol.36 , Issue.2 , pp. 180-188
    • Zeng, H.1    Chen, Q.2    Zhao, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.