-
1
-
-
0034896955
-
Nicastrin binds to membrane-tethered Notch
-
Chen F., Yu G., Arawaka S., Nishimura M., Kawarai T., Yu H., Tandon A., Supala A., Song Y.Q., Rogaeva E., Milman P., Sato C., Yu C., Janus C., Lee J., Song L., Zhang L., Fraser P.E., St George-Hyslop P.H. Nicastrin binds to membrane-tethered Notch. Nat. Cell Biol. 3:2001;751-754.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 751-754
-
-
Chen, F.1
Yu, G.2
Arawaka, S.3
Nishimura, M.4
Kawarai, T.5
Yu, H.6
Tandon, A.7
Supala, A.8
Song, Y.Q.9
Rogaeva, E.10
Milman, P.11
Sato, C.12
Yu, C.13
Janus, C.14
Lee, J.15
Song, L.16
Zhang, L.17
Fraser, P.E.18
St George-Hyslop, P.H.19
-
2
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., Roses A.D., Haines J.L., Pericak-Vance M.A. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:1993;921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
3
-
-
18344384560
-
The gene encoding Nicastrin, a major γ-Secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample
-
Dermaut B., Theuns J., Sleegers K., Hasegawa H., Van den Broeck M., Vennekens K., Corsmit E., St George-Hyslop P.H., Cruts M., van Duijn C.M., Van Broeckhoven C. The gene encoding Nicastrin, a major γ-Secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample. Am. J. Hum. Genet. 70:2002;1568-1574.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 1568-1574
-
-
Dermaut, B.1
Theuns, J.2
Sleegers, K.3
Hasegawa, H.4
Van den Broeck, M.5
Vennekens, K.6
Corsmit, E.7
St George-Hyslop, P.H.8
Cruts, M.9
Van Duijn, C.M.10
Van Broeckhoven, C.11
-
4
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease; A meta-analysis; APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer L.A., Cupples L.A., Haines J.L., Hyman B., Kukull W.A., Mayeux R., Myers R.H., Pericak-Vance M.A., Risch N., van Duijn C.M. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease; a meta-analysis; APOE and Alzheimer Disease Meta Analysis Consortium. J. Am. Med. Assoc. 278:1997;1349-1356.
-
(1997)
J. Am. Med. Assoc.
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
Myers, R.H.7
Pericak-Vance, M.A.8
Risch, N.9
Van Duijn, C.M.10
-
5
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A., Chartier-Harlin M.C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A., Irving N., James L., Mant R., Newton P., Rooke K., Roques P., Talbot C., Pericak-Vance M.A., Roses A.D., Williamson R., Rossor M., Owen M., Hardy J. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 349:1991;704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.A.16
Roses, A.D.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
6
-
-
0035856462
-
Genome-wide linkage disequilibrium mapping of late-onset Alzheimer's disease in Finland
-
Hiltunen M., Mannermaa A., Thompson D., Easton D., Pirskanen M., Helisalmi S., Koivisto A.M., Lehtovirta M., Ryynanen M., Soininen H. Genome-wide linkage disequilibrium mapping of late-onset Alzheimer's disease in Finland. Neurology. 57:2001;1663-1668.
-
(2001)
Neurology
, vol.57
, pp. 1663-1668
-
-
Hiltunen, M.1
Mannermaa, A.2
Thompson, D.3
Easton, D.4
Pirskanen, M.5
Helisalmi, S.6
Koivisto, A.M.7
Lehtovirta, M.8
Ryynanen, M.9
Soininen, H.10
-
7
-
-
0032899712
-
A full genome scan for late onset Alzheimer's disease
-
Kehoe P., Wavrant-De Vrieze F., Crook R., Wu W.S., Holmans P., Fenton I., Spurlock G., Norton N., Williams H., Williams N., Lovestone S., Perez-Tur J., Hutton M., Chartier-Harlin M.C., Shears S., Roehl K., Booth J., Van Voorst W., Ramic D., Williams J., Goate A., Hardy J., Owen M.J. A full genome scan for late onset Alzheimer's disease. Hum. Mol. Genet. 8:1999;237-245.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 237-245
-
-
Kehoe, P.1
Wavrant-De Vrieze, F.2
Crook, R.3
Wu, W.S.4
Holmans, P.5
Fenton, I.6
Spurlock, G.7
Norton, N.8
Williams, H.9
Williams, N.10
Lovestone, S.11
Perez-Tur, J.12
Hutton, M.13
Chartier-Harlin, M.C.14
Shears, S.15
Roehl, K.16
Booth, J.17
Van Voorst, W.18
Ramic, D.19
Williams, J.20
Goate, A.21
Hardy, J.22
Owen, M.J.23
more..
-
8
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of the department of health and human services task force on Alzheimer's disease
-
McKhann G., Drachman G., Folstein M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of the department of health and human services task force on Alzheimer's disease. Neurology. 34:1984;939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, G.2
Folstein, M.3
-
10
-
-
0034640140
-
Absence of linkage between familial amyotrophic lateral sclerosis and copper chaperone for the superoxide dismutase gene locus in two Italian pedigrees
-
Orlacchio A., Kawarai T., Massaro A.M., St George-Hyslop P.H., Sorbi S. Absence of linkage between familial amyotrophic lateral sclerosis and copper chaperone for the superoxide dismutase gene locus in two Italian pedigrees. Neurosci. Lett. 285:2000;83-86.
-
(2000)
Neurosci. Lett.
, vol.285
, pp. 83-86
-
-
Orlacchio, A.1
Kawarai, T.2
Massaro, A.M.3
St George-Hyslop, P.H.4
Sorbi, S.5
-
11
-
-
0037204855
-
6 receptor gene in Alzheimer's disease
-
6 receptor gene in Alzheimer's disease. Neurosci. Lett. 325:2002;13-16.
-
(2002)
Neurosci. Lett.
, vol.325
, pp. 13-16
-
-
Orlacchio, A.1
Kawarai, T.2
Paciotti, E.3
Stefani, A.4
Orlacchio, A.5
Sorbi, S.6
St George-Hyslop, P.H.7
Bernardi, G.8
-
12
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T., Mar L., Sorbi S., Nacmias B., Piacentini S., Amaducci L., Chumakov I., Cohen D., Lannfelt L., Fraser P.E., Rommens J.M., St George-Hyslop P.H. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 376:1995;775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
Mar, L.11
Sorbi, S.12
Nacmias, B.13
Piacentini, S.14
Amaducci, L.15
Chumakov, I.16
Cohen, D.17
Lannfelt, L.18
Fraser, P.E.19
Rommens, J.M.20
St George-Hyslop, P.H.21
more..
-
13
-
-
0032547369
-
Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity
-
Rogaeva E., Premkumar S., Song Y., Sorbi S., Brindle N., Paterson A., Duara R., Levesque G., Yu G., Nishimura M., Ikeda M., O'Toole C., Kawarai T., Jorge R., Vilarino D., Bruni A.C., Farrer L.A., St George-Hyslop P.H. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity. J. Am. Med. Assoc. 280:1998;614-618.
-
(1998)
J. Am. Med. Assoc.
, vol.280
, pp. 614-618
-
-
Rogaeva, E.1
Premkumar, S.2
Song, Y.3
Sorbi, S.4
Brindle, N.5
Paterson, A.6
Duara, R.7
Levesque, G.8
Yu, G.9
Nishimura, M.10
Ikeda, M.11
O'Toole, C.12
Kawarai, T.13
Jorge, R.14
Vilarino, D.15
Bruni, A.C.16
Farrer, L.A.17
St George-Hyslop, P.H.18
-
14
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R., Rogaev E.I., Liang Y., Rogaeva E.A., Levesque G., Ikeda M., Chi H., Lin C., Li G., Holman K., Tsuda T., Mar L., Foncin J.F., Bruni A.C., Montesi M.P., Sorbi S., Rainero I., Pinessi L., Nee L., Chumakov I., Pollen D., Brookes A., Sanseau P., Polinsky R.J., Wasco W., DaSilva H.A.R., Haines J.L., Pericak-Vance M.A., Tanzi R.E., Roses A.D., Fraser P.E., Rommens J.M., St George-Hyslop P.H. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375:1995;754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
DaSilva, H.A.R.26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Rommens, J.M.32
St George-Hyslop, P.H.33
more..
-
15
-
-
8944241774
-
Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant
-
Sherrington R., Froelich S., Sorbi S., Campion D., Chi H., Rogaeva E.A., Levesque G., Rogaev E.I., Lin C., Liang Y., Ikeda M., Mar L., Brice A., Agid Y., Percy M.E., Clerget-Darpoux F., Piacentini S., Marcon G., Nacmias B., Amaducci L., Frebourg T., Lannfelt L., Rommens J.M., St George-Hyslop P.H. Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant. Hum. Mol. Genet. 5:1996;985-988.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 985-988
-
-
Sherrington, R.1
Froelich, S.2
Sorbi, S.3
Campion, D.4
Chi, H.5
Rogaeva, E.A.6
Levesque, G.7
Rogaev, E.I.8
Lin, C.9
Liang, Y.10
Ikeda, M.11
Mar, L.12
Brice, A.13
Agid, Y.14
Percy, M.E.15
Clerget-Darpoux, F.16
Piacentini, S.17
Marcon, G.18
Nacmias, B.19
Amaducci, L.20
Frebourg, T.21
Lannfelt, L.22
Rommens, J.M.23
St George-Hyslop, P.H.24
more..
-
16
-
-
0035115610
-
Variable phenotype of Alzheimer's disease with spastic paraparesis
-
Smith M.J., Kwok J.B., McLean C.A., Kril J.J., Broe G.A., Nicholson G.A., Cappai R., Hallupp M., Cotton R.G., Masters C.L., Schofield P.R., Brooks W.S. Variable phenotype of Alzheimer's disease with spastic paraparesis. Ann. Neurol. 49:2001;125-129.
-
(2001)
Ann. Neurol.
, vol.49
, pp. 125-129
-
-
Smith, M.J.1
Kwok, J.B.2
McLean, C.A.3
Kril, J.J.4
Broe, G.A.5
Nicholson, G.A.6
Cappai, R.7
Hallupp, M.8
Cotton, R.G.9
Masters, C.L.10
Schofield, P.R.11
Brooks, W.S.12
-
17
-
-
0028137052
-
ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease
-
Sorbi S., Nacmias B., Forleo P., Latorraca S., Gobbini I., Bracco L., Piacentini S., Amaducci L. ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease. Neurosci. Lett. 177:1994;100-102.
-
(1994)
Neurosci. Lett.
, vol.177
, pp. 100-102
-
-
Sorbi, S.1
Nacmias, B.2
Forleo, P.3
Latorraca, S.4
Gobbini, I.5
Bracco, L.6
Piacentini, S.7
Amaducci, L.8
-
18
-
-
0028288703
-
Alzheimer's disease and possible gene interaction
-
St George-Hyslop P.H., McLachlan D.C., Tsuda T., Rogaev E., Karlinsky H., Lippa C.F., Pollen D., Tuda T. Alzheimer's disease and possible gene interaction. Science. 263:1994;537.
-
(1994)
Science
, vol.263
, pp. 537
-
-
St George-Hyslop, P.H.1
McLachlan, D.C.2
Tsuda, T.3
Rogaev, E.4
Karlinsky, H.5
Lippa, C.F.6
Pollen, D.7
Tuda, T.8
-
20
-
-
0034618715
-
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and β-APP processing
-
Yu G., Nishimura M., Arawaka S., Levitan D., Zhang L., Tandon A., Song Y.Q., Rogaeva E., Chen F., Kawarai T., Supala A., Levesque L., Yu H., Yang D.S., Holmes E., Milman P., Liang y., Zhang D.M., Xu D.H., Sato C., Rogaev E., Smith M., Janus C., Zhang Y., Aebersold R., Farrer L.S., Sorbi S., Bruni A., Fraser P., St George-Hyslop P.H. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and β-APP processing. Nature. 407:2000;48-54.
-
(2000)
Nature
, vol.407
, pp. 48-54
-
-
Yu, G.1
Nishimura, M.2
Arawaka, S.3
Levitan, D.4
Zhang, L.5
Tandon, A.6
Song, Y.Q.7
Rogaeva, E.8
Chen, F.9
Kawarai, T.10
Supala, A.11
Levesque, L.12
Yu, H.13
Yang, D.S.14
Holmes, E.15
Milman, P.16
Liang, y.17
Zhang, D.M.18
Xu, D.H.19
Sato, C.20
Rogaev, E.21
Smith, M.22
Janus, C.23
Zhang, Y.24
Aebersold, R.25
Farrer, L.S.26
Sorbi, S.27
Bruni, A.28
Fraser, P.29
St George-Hyslop, P.H.30
more..
|