Telomere length as a biomarker for adiposity changes after a multidisciplinary intervention in overweight/obese adolescents: The EVASYON study

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  García Calzón, Sonia ^a   Moleres, Adriana ^a   Marcos, Ascensión ^b   Campoy, Cristina ^c   Moreno, Luis A ^d   Azcona Sanjulián, M Cristina ^e   Martínez González, Miguel A ^a,f   Martínez, Alfredo ^a,f   Zalba, Guillermo ^a   Marti, Amelia ^a,f  

^a UNIVERSITY OF NAVARRA   (Spain)

^b INSTITUTE OF FOOD SCIENCE   (Spain)

^c UNIVERSITY OF GRANADA   (Spain)

^d UNIVERSITY OF ZARAGOZA   (Spain)

^e Instituto de Investigación Sanitaria de Navarra   (Spain)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; PRIMER DNA;

ADOLESCENT; ARTICLE; BODY MASS; CHILD; DIET RESTRICTION; DISEASE MARKER; EATING HABIT; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; OUTCOME ASSESSMENT; PHYSICAL ACTIVITY; PREDICTION; REAL TIME POLYMERASE CHAIN REACTION; TELOMERE HOMEOSTASIS; TREATMENT RESPONSE; WEIGHT REDUCTION; ANTHROPOMETRY; CHEMISTRY; GENETICS; LOW CALORY DIET; OVERWEIGHT; PHYSIOLOGY; PROCEDURES; STATISTICAL MODEL; TELOMERE;

ADIPOSITY; ADOLESCENT; ANTHROPOMETRY; BIOLOGICAL MARKERS; DIET, REDUCING; DNA PRIMERS; FEMALE; HUMANS; LINEAR MODELS; MALE; OBESITY; OVERWEIGHT; REAL-TIME POLYMERASE CHAIN REACTION; TELOMERE; WEIGHT REDUCTION PROGRAMS;

EID: 84896098520     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089828     Document Type: Article

References (36)

1. Blackburn EH (1991) Structure and function of telomeres. Nature 350: 569-573.
2. Shalev I, Entringer S, Wadhwa PD, Wolkowitz OM, Puterman E, et al. (2013) Stress and telomere biology: A lifespan perspective. Psychoneuroendocrinology 10.1016/j.psyneuen.2013.03.010.
3. Aviv A (2008) The epidemiology of human telomeres: faults and promises. J Gerontol A Biol Sci Med Sci 63: 979-983.
4. de Onis M, Blossner M, Borghi E (2010) Global prevalence and trends of overweight and obesity among preschool children. Am J Clin Nutr 92: 1257-1264.
5. Crocker MK, Yanovski JA (2011) Pediatric obesity: etiology and treatment. Pediatr Clin North Am 58: 1217-1240, xi.
6. Rankin JW, Andreae MC, Oliver Chen CY, O'Keefe SF (2008) Effect of raisin consumption on oxidative stress and inflammation in obesity. Diabetes Obes Metab 10: 1086-1096.
7. Suzuki K, Ito Y, Ochiai J, Kusuhara Y, Hashimoto S, et al. (2003) Relationship between obesity and serum markers of oxidative stress and inflammation in Japanese. Asian Pac J Cancer Prev 4: 259-266.
8. Lee M, Martin H, Firpo MA, Demerath EW (2011) Inverse association between adiposity and telomere length: The Fels Longitudinal Study. Am J Hum Biol 23: 100-106.
9. Njajou OT, Cawthon RM, Blackburn EH, Harris TB, Li R, et al. (2012) Shorter telomeres are associated with obesity and weight gain in the elderly. Int J Obes (Lond) 36: 1176-1179.
10. Cui Y, Gao YT, Cai Q, Qu S, Cai H, et al. (2013) Associations of leukocyte telomere length with body anthropometric indices and weight change in chinese women. Obesity (Silver Spring) 10.1002/oby.20321.
11. Garcia-Calzon S, Gea A, Razquin C, Corella D, Lamuela-Raventos RM, et al. (2013) Longitudinal association of telomere length and obesity indices in an intervention study with a Mediterranean diet: the PREDIMED-NAVARRA trial. Int J Obes (Lond) 10.1038/ijo.2013.68.
12. Bekaert S, De Meyer T, Rietzschel ER, De Buyzere ML, De Bacquer D, et al. (2007) Telomere length and cardiovascular risk factors in a middle-aged population free of overt cardiovascular disease. Aging Cell 6: 639-647. (Pubitemid 47400046)
13. Diaz VA, Mainous AG, Player MS, Everett CJ (2010) Telomere length and adiposity in a racially diverse sample. Int J Obes (Lond) 34: 261-265.
14. Zannolli R, Mohn A, Buoni S, Pietrobelli A, Messina M, et al. (2008) Telomere length and obesity. Acta Paediatr 97: 952-954. (Pubitemid 351792805)
15. Al-Attas OS, Al-Daghri N, Bamakhramah A, Shaun Sabico S, McTernan P, et al. (2010) Telomere length in relation to insulin resistance, inflammation and obesity among Arab youth. Acta Paediatr 99: 896-899.
16. Buxton JL, Walters RG, Visvikis-Siest S, Meyre D, Froguel P, et al. (2011) Childhood obesity is associated with shorter leukocyte telomere length. J Clin Endocrinol Metab 96: 1500-1505.
17. Zhu H, Wang X, Gutin B, Davis CL, Keeton D, et al. (2011) Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity. J Pediatr 158: 215-220.
18. O'Callaghan NJ, Clifton PM, Noakes M, Fenech M (2009) Weight loss in obese men is associated with increased telomere length and decreased abasic sites in rectal mucosa. Rejuvenation Res 12: 169-176.
19. Gardner JP, Li S, Srinivasan SR, Chen W, Kimura M, et al. (2005) Rise in insulin resistance is associated with escalated telomere attrition. Circulation 111: 2171-2177. (Pubitemid 40632431)
20. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 320: 1240-1243. (Pubitemid 30240471)
21. National Research Council, Food and Nutrition Board (2005) Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids: National Academy Press. Washington DC.
22. Martinez-Gomez D, Gomez-Martinez S, Puertollano MA, Nova E, Warnberg J, et al. (2009) Design and evaluation of a treatment programme for Spanish adolescents with overweight and obesity. The EVASYON Study. BMC Public Health 9: 414.
23. Marques M, Moleres A, Rendo-Urteaga T, Gomez-Martinez S, Zapatera B, et al. (2012) Design of the nutritional therapy for overweight and obese Spanish adolescents conducted by registered dieticians: the EVASYON study. Nutr Hosp 27: 165-176.
24. Moreno LA, Mesana MI, Gonzalez-Gross M, Gil CM, Ortega FB, et al. (2007) Body fat distribution reference standards in Spanish adolescents: the AVENA Study. Int J Obes (Lond) 31: 1798-1805. (Pubitemid 350174625)
25. Slaughter MH, Lohman TG, Boileau RA, Horswill CA, Stillman RJ, et al. (1988) Skinfold equations for estimation of body fatness in children and youth. Hum Biol 60: 709-723.
26. Cawthon RM (2002) Telomere measurement by quantitative PCR. Nucleic Acids Res 30: e47.
27. Kiecolt-Glaser JK, Epel ES, Belury MA, Andridge R, Lin J, et al. (2013) Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial. Brain Behav Immun 28: 16-24.
28. Marin C, Delgado-Lista J, Ramirez R, Carracedo J, Caballero J, et al. (2012) Mediterranean diet reduces senescence-associated stress in endothelial cells. Age (Dordr) 34: 1309-1316.
29. Epel E (2012) How "reversible" is telomeric aging? Cancer Prev Res (Phila) 5: 1163-1168.
30. Nordfjall K, Svenson U, Norrback KF, Adolfsson R, Lenner P, et al. (2009) The individual blood cell telomere attrition rate is telomere length dependent. PLoS Genet 5: e1000375.
31. Aviv A, Chen W, Gardner JP, Kimura M, Brimacombe M, et al. (2009) Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. Am J Epidemiol 169: 323-329.
32. Hovatta I, de Mello VD, Kananen L, Lindstrom J, Eriksson JG, et al. (2012) Leukocyte telomere length in the Finnish Diabetes Prevention Study. PLoS One 7: e34948.
33. Ouellette MM, Liao M, Herbert BS, Johnson M, Holt SE, et al. (2000) Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase. J Biol Chem 275: 10072-10076. (Pubitemid 30202057)
34. Samper E, Flores JM, Blasco MA (2001) Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Rep 2: 800-807. (Pubitemid 32982748)
35. Teixeira MT, Arneric M, Sperisen P, Lingner J (2004) Telomere length homeostasis is achieved via a switch between telomerase- extendible and - nonextendible states. Cell 117: 323-335. (Pubitemid 38534539)
36. Steenstrup T, Hjelmborg JV, Kark JD, Christensen K, Aviv A (2013) The telomere lengthening conundrum-artifact or biology? Nucleic Acids Res 41: e131.