-
1
-
-
33745516977
-
Dyskeratosis congenita
-
Vulliomy T, Dokal I. Dyskeratosis congenita. Semin Hematol. 2006;43:157-166.
-
(2006)
Semin Hematol
, vol.43
, pp. 157-166
-
-
Vulliomy, T.1
Dokal, I.2
-
2
-
-
34250614359
-
Adult-onset pulmonary fibrosis caused by mutations in telomerase
-
Tsakiri KD, Cronkhite JT, Kuan PJ, et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc Natl Acad Sci U S A. 2007;104:7552-7557.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7552-7557
-
-
Tsakiri, K.D.1
Cronkhite, J.T.2
Kuan, P.J.3
-
3
-
-
34547617380
-
-
Martin GM, Bergman A, Barzilai N. Genetic determinants of human health span and life span: progress and new opportunities. PLoS Genet. 2007;3:e125.doi:10.1371/journal.pgen.0030125.
-
Martin GM, Bergman A, Barzilai N. Genetic determinants of human health span and life span: progress and new opportunities. PLoS Genet. 2007;3:e125.doi:10.1371/journal.pgen.0030125.
-
-
-
-
4
-
-
34249818182
-
Tissue-specific transcriptional regulation has diverged significantly between human and mouse
-
Odom DT, Dowell RD, Jacobsen ES, et al. Tissue-specific transcriptional regulation has diverged significantly between human and mouse. Nat Genet. 2007;39:730-732.
-
(2007)
Nat Genet
, vol.39
, pp. 730-732
-
-
Odom, D.T.1
Dowell, R.D.2
Jacobsen, E.S.3
-
5
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell. 2005;120:449-460.
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
6
-
-
27544434895
-
The insulin/IGF-1 signaling in mammals and its relevance to human longevity
-
Rincon M, Rudin E, Barzilai N. The insulin/IGF-1 signaling in mammals and its relevance to human longevity. Exp Gerentol. 2005;40:873-877.
-
(2005)
Exp Gerentol
, vol.40
, pp. 873-877
-
-
Rincon, M.1
Rudin, E.2
Barzilai, N.3
-
7
-
-
13444302623
-
Insulin-like growth factors and coronary heart disease
-
Kaplan RC, Strickler HD, Rohan TE, Muzumdar R, Brown DL. Insulin-like growth factors and coronary heart disease. Cardiol Rev. 2005;13:35-39.
-
(2005)
Cardiol Rev
, vol.13
, pp. 35-39
-
-
Kaplan, R.C.1
Strickler, H.D.2
Rohan, T.E.3
Muzumdar, R.4
Brown, D.L.5
-
8
-
-
27544492807
-
Control of aging and longevity by IGF-1 signaling
-
Yang J, Anzo M, Cohen P. Control of aging and longevity by IGF-1 signaling. Exp Gerontol. 2005;40:867-872.
-
(2005)
Exp Gerontol
, vol.40
, pp. 867-872
-
-
Yang, J.1
Anzo, M.2
Cohen, P.3
-
9
-
-
0033135266
-
Rapid telomere shortening in children
-
Zeichner SL, Palumbo P, Feng X, et al. Rapid telomere shortening in children. Blood. 1999;93:2824-2830.
-
(1999)
Blood
, vol.93
, pp. 2824-2830
-
-
Zeichner, S.L.1
Palumbo, P.2
Feng, X.3
-
10
-
-
0345643319
-
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood
-
Ruffer N, Brummendorf TH, Kolvraa S, et al. Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med. 1999;190:157-167.
-
(1999)
J Exp Med
, vol.190
, pp. 157-167
-
-
Ruffer, N.1
Brummendorf, T.H.2
Kolvraa, S.3
-
12
-
-
33644993680
-
Telomere length in small-for-gestational-age babies
-
Akkad A, Hastings R, Konje JC, Bell SC, Thurston H, Williams B. Telomere length in small-for-gestational-age babies. BJOG. 2006;113:318-323.
-
(2006)
BJOG
, vol.113
, pp. 318-323
-
-
Akkad, A.1
Hastings, R.2
Konje, J.C.3
Bell, S.C.4
Thurston, H.5
Williams, B.6
-
13
-
-
18244386227
-
rise in insulin resistance is associated with escalated telomere attrition
-
Gardner JP, Li S, Srinivasan SR, et al. rise in insulin resistance is associated with escalated telomere attrition. Circulation. 2005;111:2171-2177.
-
(2005)
Circulation
, vol.111
, pp. 2171-2177
-
-
Gardner, J.P.1
Li, S.2
Srinivasan, S.R.3
-
15
-
-
23844517498
-
Obesity, cigarette smoking, and telomere length in women
-
Valdes A, Andrew T, Gardner JP, et al. Obesity, cigarette smoking, and telomere length in women. Lancet. 2005;366:662-664.
-
(2005)
Lancet
, vol.366
, pp. 662-664
-
-
Valdes, A.1
Andrew, T.2
Gardner, J.P.3
-
16
-
-
34548649135
-
Shared environmental factors associated with telomere length maintenance in elderly male twins
-
Huda N, Tanaka H, Herbert BS, Reed T, Gilley D. Shared environmental factors associated with telomere length maintenance in elderly male twins. Aging Cell. 2007;6:709-713.
-
(2007)
Aging Cell
, vol.6
, pp. 709-713
-
-
Huda, N.1
Tanaka, H.2
Herbert, B.S.3
Reed, T.4
Gilley, D.5
-
17
-
-
34547546721
-
Telomere length is paternally inherited and is associated with paternal lifespan
-
Njajou OT, Cawthon RM, Damcott CM, et al. Telomere length is paternally inherited and is associated with paternal lifespan. Proc Natl Acad Sci U S A. 2007;104:12135-12139.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12135-12139
-
-
Njajou, O.T.1
Cawthon, R.M.2
Damcott, C.M.3
-
19
-
-
33845864725
-
Leukocyte telomere length and cardiovascular disease in the Cardiovascular Health Study
-
Fitzpatrick AL, Kronmal RA, Gardner JP, et al. Leukocyte telomere length and cardiovascular disease in the Cardiovascular Health Study. Am J Epidemiol. 2007;165:14-21.
-
(2007)
Am J Epidemiol
, vol.165
, pp. 14-21
-
-
Fitzpatrick, A.L.1
Kronmal, R.A.2
Gardner, J.P.3
-
20
-
-
33746316181
-
Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study
-
Demissie S, Levy D, Benjamin EJ, et al. Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study. Aging Cell. 2006;5:325-330.
-
(2006)
Aging Cell
, vol.5
, pp. 325-330
-
-
Demissie, S.1
Levy, D.2
Benjamin, E.J.3
-
21
-
-
33745600820
-
Asymmetric and symmetric stem-cell divisions in development and cancer
-
Morrison SJ, Kimble J. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature. 2006;441:1068-1074.
-
(2006)
Nature
, vol.441
, pp. 1068-1074
-
-
Morrison, S.J.1
Kimble, J.2
-
22
-
-
8844251482
-
Regulation of hematopoietic cell growth
-
Attar EC, Scadden DT. Regulation of hematopoietic cell growth. Leukemia. 2004;18:1760-1768.
-
(2004)
Leukemia
, vol.18
, pp. 1760-1768
-
-
Attar, E.C.1
Scadden, D.T.2
-
23
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med. 2006;12:446-451.
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
-
24
-
-
0036139411
-
Modeling telomere shortening and the role of oxidative stress
-
Proctor CJ, Kirkwood TBL. Modeling telomere shortening and the role of oxidative stress. Mech Ageing Dev. 2002;123:351-363.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 351-363
-
-
Proctor, C.J.1
Kirkwood, T.B.L.2
-
25
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell. 2005;120:483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
26
-
-
4544322522
-
Inflammatory exposure and historical changes in human life-spans
-
Finch C, Crimmins EM. Inflammatory exposure and historical changes in human life-spans. Science. 2004;305:1736-1739.
-
(2004)
Science
, vol.305
, pp. 1736-1739
-
-
Finch, C.1
Crimmins, E.M.2
-
27
-
-
33749534161
-
Telomeres and telomerase: The path from maize, Tetrahymena and yeast to human cancer and aging
-
Blackburn EH, Greider CW, Szostak JW. Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med. 2006;12:1133-1138.
-
(2006)
Nat Med
, vol.12
, pp. 1133-1138
-
-
Blackburn, E.H.1
Greider, C.W.2
Szostak, J.W.3
-
28
-
-
33947576976
-
MERIT-HF Study Group. Telomere length of circulating leukocytes is decreased in patients with chronic heart failure
-
van der Harst P, van der Steege G, de Boer RA, et al. MERIT-HF Study Group. Telomere length of circulating leukocytes is decreased in patients with chronic heart failure. J Am Coll Cardiol. 2007;49:1459-1464.
-
(2007)
J Am Coll Cardiol
, vol.49
, pp. 1459-1464
-
-
van der Harst, P.1
van der Steege, G.2
de Boer, R.A.3
-
29
-
-
0038640076
-
White cell telomere length and risk of premature myocardial infarction
-
Brouilette S, Singh RK, Thompson JR, Goodall AH, Samani NJ. White cell telomere length and risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol. 2003;23:842-846.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 842-846
-
-
Brouilette, S.1
Singh, R.K.2
Thompson, J.R.3
Goodall, A.H.4
Samani, N.J.5
-
30
-
-
0037308404
-
Association between telomere length in blood and mortality in people aged 60 years or older
-
Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet. 2003;361:393-395.
-
(2003)
Lancet
, vol.361
, pp. 393-395
-
-
Cawthon, R.M.1
Smith, K.R.2
O'Brien, E.3
Sivatchenko, A.4
Kerber, R.A.5
-
31
-
-
10744225878
-
Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects
-
Benetos A, Gardner JP, Zureik M, et al. Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects. Hypertension. 2004;43:182-185.
-
(2004)
Hypertension
, vol.43
, pp. 182-185
-
-
Benetos, A.1
Gardner, J.P.2
Zureik, M.3
-
32
-
-
33846049673
-
West of Scotland Coronary Prevention Study Group. Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: A nested case-control study
-
Brouilette SW, Moore JS, McMahon AD, et al. West of Scotland Coronary Prevention Study Group. Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet. 2007;369:107-114.
-
(2007)
Lancet
, vol.369
, pp. 107-114
-
-
Brouilette, S.W.1
Moore, J.S.2
McMahon, A.D.3
-
33
-
-
33746828140
-
Telomere length predicts poststroke mortality, dementia, and cognitive decline
-
Martin-Ruiz C, Dickinson HO, Keys B, Rowan E, Kenny RA, von Zglinicki T. Telomere length predicts poststroke mortality, dementia, and cognitive decline. Ann Neurol. 2006;60:174-180.
-
(2006)
Ann Neurol
, vol.60
, pp. 174-180
-
-
Martin-Ruiz, C.1
Dickinson, H.O.2
Keys, B.3
Rowan, E.4
Kenny, R.A.5
von Zglinicki, T.6
-
34
-
-
0037213048
-
Telomere shortening in T cells correlates with Alzheimer's disease status
-
Panossian LA, Porter VR, Valenzuela HF, et al. Telomere shortening in T cells correlates with Alzheimer's disease status. Neurobiol Aging. 2003;24:77-84.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 77-84
-
-
Panossian, L.A.1
Porter, V.R.2
Valenzuela, H.F.3
-
35
-
-
33746812586
-
Shorter telomeres are associated with mortality in those with APOE epsilon 4 and dementia
-
Honig LS, Schupf N, Lee JH, Tang MX, Mayeux R. Shorter telomeres are associated with mortality in those with APOE epsilon 4 and dementia. Ann Neurol. 2006;60:181-187.
-
(2006)
Ann Neurol
, vol.60
, pp. 181-187
-
-
Honig, L.S.1
Schupf, N.2
Lee, J.H.3
Tang, M.X.4
Mayeux, R.5
-
36
-
-
34548625163
-
on behalf of the Asklepios investigators. Telomere length and cardiovascular risk factors in middle-aged population free of overt cardiovascular disease
-
Bekaert S, De Meyer T, Rietzschel ER, et al., on behalf of the Asklepios investigators. Telomere length and cardiovascular risk factors in middle-aged population free of overt cardiovascular disease. Aging Cell. 2007;6:639-47.
-
(2007)
Aging Cell
, vol.6
, pp. 639-647
-
-
Bekaert, S.1
De Meyer, T.2
Rietzschel, E.R.3
-
37
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature. 1990;345:458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
38
-
-
2342419515
-
Telomere measurement by quantitative PCR
-
Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res. 2002;30:e47.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Cawthon, R.M.1
-
39
-
-
0031879115
-
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
-
Rufer N, Dragowska W, Thornbury G, Roosnek E, Lansdorp PM. Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat Biotechnol. 1998;16:743-747.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 743-747
-
-
Rufer, N.1
Dragowska, W.2
Thornbury, G.3
Roosnek, E.4
Lansdorp, P.M.5
-
40
-
-
34548852722
-
Flow cytometry and FISH to measure the average length of telomeres (flow FISH)
-
Baerlocher GM, Vulto I, de Jong G, Lansdorp PM. Flow cytometry and FISH to measure the average length of telomeres (flow FISH). Nat Protoc. 2006;1:2365-2376.
-
(2006)
Nat Protoc
, vol.1
, pp. 2365-2376
-
-
Baerlocher, G.M.1
Vulto, I.2
de Jong, G.3
Lansdorp, P.M.4
-
41
-
-
34248370975
-
High-throughput telomere length quantification by FISH and its application to human population studies
-
Canela A, Vera E, Klatt P, Blasco MA. High-throughput telomere length quantification by FISH and its application to human population studies. Proc Natl Acad Sci U S A. 2007;104:5300-5305.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5300-5305
-
-
Canela, A.1
Vera, E.2
Klatt, P.3
Blasco, M.A.4
-
42
-
-
0025086570
-
Structure and polymorphism of human telomere-associated DNA
-
Brown WR, Mackinnon PJ, Villasante A, Spurr N, Buckle VJ, Dobson MJ. Structure and polymorphism of human telomere-associated DNA. Cell. 1990;63:119-132.
-
(1990)
Cell
, vol.63
, pp. 119-132
-
-
Brown, W.R.1
Mackinnon, P.J.2
Villasante, A.3
Spurr, N.4
Buckle, V.J.5
Dobson, M.J.6
-
43
-
-
33646794390
-
No association between telomere length and survival among the elderly and oldest old
-
Bischoff C, Petersen HC, Graakjaer J, et al. No association between telomere length and survival among the elderly and oldest old. Epidemiology. 2006;17:190-194.
-
(2006)
Epidemiology
, vol.17
, pp. 190-194
-
-
Bischoff, C.1
Petersen, H.C.2
Graakjaer, J.3
-
44
-
-
33644822655
-
Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: A population-based study
-
Martin-Ruiz CM, Gussekloo J, van Heemst D, von Zglinicki T, Westendorp RG. Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study. Aging Cell. 2005;4:287-290.
-
(2005)
Aging Cell
, vol.4
, pp. 287-290
-
-
Martin-Ruiz, C.M.1
Gussekloo, J.2
van Heemst, D.3
von Zglinicki, T.4
Westendorp, R.G.5
-
45
-
-
33748177309
-
The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people
-
Harris SE, Deary IJ, MacIntyre A, et al. The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people. Neurosci Lett. 2006;406:260-264.
-
(2006)
Neurosci Lett
, vol.406
, pp. 260-264
-
-
Harris, S.E.1
Deary, I.J.2
MacIntyre, A.3
-
46
-
-
41349113994
-
Short leukocyte telomeres forecast mortality: A study in elderly Danish twins
-
Kimura M, Hjelmborg JV, Gardner JP, et al. Short leukocyte telomeres forecast mortality: a study in elderly Danish twins. Am J Epidemiol. 2008;167:799-806.
-
(2008)
Am J Epidemiol
, vol.167
, pp. 799-806
-
-
Kimura, M.1
Hjelmborg, J.V.2
Gardner, J.P.3
-
47
-
-
36248965748
-
Telomere length predicts survival independent of genetic influences
-
Bakaysa SL, Mucci LA, Slagboom PE, et al. Telomere length predicts survival independent of genetic influences. Aging Cell. 2007;6:769-774.
-
(2007)
Aging Cell
, vol.6
, pp. 769-774
-
-
Bakaysa, S.L.1
Mucci, L.A.2
Slagboom, P.E.3
-
48
-
-
0031903483
-
Synchrony in telomere length of the human fetus
-
Youngren K, Jeanclos E, Aviv H, et al. Synchrony in telomere length of the human fetus. Hum Genet. 1998;102:640-643.
-
(1998)
Hum Genet
, vol.102
, pp. 640-643
-
-
Youngren, K.1
Jeanclos, E.2
Aviv, H.3
|