Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation

Experimental Eye Research

Volumn 121, Issue , 2014, Pages 130-142

  Teo, Zhi Ling ^a,d   McQueen Miscamble, Lachlan ^a   Turner, Kirsty ^a   Martinez, Gemma ^a   Madakashira, Bhavani ^b   Dedhar, Shoukat ^c   Robinson, Michael L ^b   De Iongh, Robb U ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MIAMI UNIVERSITY   (United States)

^c BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^d PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

Apoptosis; Cell cycle; EMT; Integrin linked kinase; Lens development; MAPK signalling; PI3K signalling; Signalling

Indexed keywords

ALPHA ACTININ 2; ARHGAP5 PROTEIN; BETA CRYSTALLIN; BROXURIDINE; CAV1 PROTEIN; COLLAGEN TYPE 4; CRK LIKE PROTEIN; CRK PROTEIN; CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE INHIBITOR 1C; DOCK1 PROTEIN; DST PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2 ALPHA; HISTONE H3; INTEGRIN; INTEGRIN LINKED KINASE; ITGA2 PROTEIN; ITGA5 PROTEIN; ITGA9 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; P21 ACTIVATED KINASE 1; P21 ACTIVATED KINASE 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B BETA; PROTEIN TYROSINE PHOSPHATASE SHP 2; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG; UVOMORULIN;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL CYCLE PROGRESSION; CELL DEATH; CELL DEGENERATION; CELL DIFFERENTIATION; CELL LOSS; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FOCAL ADHESION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; LENS CAPSULE RUPTURE; LENS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL CYCLE; EMT; INTEGRIN LINKED KINASE; LENS DEVELOPMENT; MAPK SIGNALLING; PI3K SIGNALLING; SIGNALLING;

ANIMALS; BLOTTING, WESTERN; CADHERINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN D1; CYCLIN D2; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; LENS, CRYSTALLINE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84895961650     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2014.01.013     Document Type: Article

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