Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly

Hepatology

Volumn 48, Issue 6, 2008, Pages 1932-1941

  Gkretsi, Vasiliki ^a   Apte, Udayan ^a   Mars, Wendy M ^a   Bowen, William C ^a   Luo, Jian Hua ^a   Yang, Yu ^a   Yu, Yan P ^a   Orr, Ann ^a   St Arnaud, René ^b   Dedhar, Shoukat ^c   Kaestner, Klaus H ^d   Wu, Chuanyue ^a   Michalopoulos, George K ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALPHA FETOPROTEIN; BETA CATENIN; CRE RECOMBINASE; INTEGRIN; INTEGRIN LINKED KINASE; MATRIX PROTEIN; INTEGRASE; INTEGRIN-LINKED KINASE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BREEDING; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION; HEPATOMEGALY; HISTOPATHOLOGY; IN VIVO STUDY; LIVER CELL; LIVER DISEASE; LIVER METABOLISM; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STABILITY; UPREGULATION; WILD TYPE; AGING; ANIMAL; DISEASE MODEL; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AGING; ANIMALS; BETA CATENIN; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; HEPATOCYTES; HEPATOMEGALY; INTEGRASES; LIVER; MICE; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 58149401291     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22537     Document Type: Article

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