Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (gsk-3β) phosphorylation

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Maydan, Mykola ^a   McDonald, Paul C ^a   Sanghera, Jasbinder ^b   Yan, Jun ^b   Rallis, Charalampos ^c,d   Pinchin, Sheena ^c,d   Hannigan, Gregory E ^e   Foster, Leonard J ^f   Ish Horowicz, David ^c   Walsh, Michael P ^g   Dedhar, Shoukat ^a,f  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b SignalChem Inc   (Canada)

^c London Research Institute   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^g UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLYCOGEN SYNTHASE KINASE 3BETA; INTEGRIN LINKED KINASE; LYSINE; MANGANESE; MYOSIN LIGHT CHAIN; PROTEIN KINASE; RECOMBINANT ENZYME; ACTININ; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INTEGRIN-LINKED KINASE; PARVA PROTEIN, HUMAN; PEPTIDE; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN EXPRESSION; ANIMAL; CELL LINE; CHEMISTRY; ENZYME ACTIVATION; ENZYME SPECIFICITY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS;

ACTININ; ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; KINETICS; LYSINE; MANGANESE; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 77957859815     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012356     Document Type: Article

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