Release of neuronal HMGB1 by ethanol through decreased HDAC activity activates brain neuroimmune signaling

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Zou, Jian Y ^a   Crews, Fulton T ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; GLYCYRRHIZIC ACID; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE INHIBITOR; INTERLEUKIN 1BETA; MESSENGER RNA; NEUTRALIZING ANTIBODY; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ACETYLATION; ALCOHOLISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; ENTORHINAL CORTEX; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE EXPRESSION; HIPPOCAMPUS; MICROGLIA; MOUSE; NERVE CELL; NEUROIMMUNOLOGY; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION;

ACETYLATION; ANIMALS; BENZAMIDES; BLOTTING, WESTERN; BRAIN; CELL NUCLEUS; CYTOKINES; CYTOSOL; ENTORHINAL CORTEX; ETHANOL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HMGB1 PROTEIN; HUMANS; HYDROXAMIC ACIDS; INFLAMMATION MEDIATORS; MICE; MICROGLIA; MODELS, BIOLOGICAL; NALTREXONE; NEURONS; PYRIDINES; RATS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84895894114     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087915     Document Type: Article

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