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Volumn 25, Issue SUPPL. 1, 2011, Pages

Alcoholism and inflammation: Neuroimmunology of behavioral and mood disorders

Author keywords

2,3 Indoleamine 2; 3 Dioxygenase; Alcoholism; Depressive like behavior; Kynurenine; Pro inflammatory cytokines; Sickness behavior

Indexed keywords

ALPHA INTERFERON; BCG VACCINE; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TRYPTOPHAN;

EID: 79955717804     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2010.12.013     Document Type: Review
Times cited : (115)

References (89)
  • 4
    • 65549165522 scopus 로고    scopus 로고
    • Activation of liver tryptophan pyrrolase mediates the decrease in tryptophan availability to the brain after acute alcohol consumption by normal subjects
    • Badawy A.A., Doughrty D.M., Marsh-Richard D.M., Steptoe A. Activation of liver tryptophan pyrrolase mediates the decrease in tryptophan availability to the brain after acute alcohol consumption by normal subjects. Alcohol and Alcoholism (Oxford, Oxfordshire) 2009, 44:267-271.
    • (2009) Alcohol and Alcoholism (Oxford, Oxfordshire) , vol.44 , pp. 267-271
    • Badawy, A.A.1    Doughrty, D.M.2    Marsh-Richard, D.M.3    Steptoe, A.4
  • 5
    • 0025878385 scopus 로고
    • Receptors for interleukin-1 (alpha and beta) in mouse brain: mapping and neuronal localization in hippocampus
    • Ban E., Milon G., Prudhomme N., Fillion G., Haour F. Receptors for interleukin-1 (alpha and beta) in mouse brain: mapping and neuronal localization in hippocampus. Neuroscience 1991, 43:21-30.
    • (1991) Neuroscience , vol.43 , pp. 21-30
    • Ban, E.1    Milon, G.2    Prudhomme, N.3    Fillion, G.4    Haour, F.5
  • 7
    • 0023231717 scopus 로고
    • Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1
    • Berkenbosch F., van Oers J., del Rey A., Tilders F., Besedovsky H. Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1. Science 1987, 238:524-526.
    • (1987) Science , vol.238 , pp. 524-526
    • Berkenbosch, F.1    van Oers, J.2    del Rey, A.3    Tilders, F.4    Besedovsky, H.5
  • 8
    • 0020404031 scopus 로고
    • Activation of tryptophan pyrrolase after chronic alcohol administration
    • Branchey L., Lieber C.S. Activation of tryptophan pyrrolase after chronic alcohol administration. Substance and Alcohol Actions/Misuse 1982, 3:225-229.
    • (1982) Substance and Alcohol Actions/Misuse , vol.3 , pp. 225-229
    • Branchey, L.1    Lieber, C.S.2
  • 11
    • 0033614362 scopus 로고    scopus 로고
    • Prediction of the depressive effects of interferon alfa therapy by the patient's initial affective state
    • Capuron L., Ravaud A. Prediction of the depressive effects of interferon alfa therapy by the patient's initial affective state. The New England Journal of Medicine 1999, 340:1370.
    • (1999) The New England Journal of Medicine , vol.340 , pp. 1370
    • Capuron, L.1    Ravaud, A.2
  • 12
    • 0034079672 scopus 로고    scopus 로고
    • Early depressive symptoms in cancer patients receiving interleukin 2 and/or interferon alfa-2b therapy
    • Capuron L., Ravaud A., Dantzer R. Early depressive symptoms in cancer patients receiving interleukin 2 and/or interferon alfa-2b therapy. Journal of Clinical Oncology 2000, 18:2143-2151.
    • (2000) Journal of Clinical Oncology , vol.18 , pp. 2143-2151
    • Capuron, L.1    Ravaud, A.2    Dantzer, R.3
  • 13
    • 0035985472 scopus 로고    scopus 로고
    • Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy
    • Capuron L., Ravaud A., Neveu P.J., Miller A.H., Maes M., Dantzer R. Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy. Molecular Psychiatry 2002, 7:468-473.
    • (2002) Molecular Psychiatry , vol.7 , pp. 468-473
    • Capuron, L.1    Ravaud, A.2    Neveu, P.J.3    Miller, A.H.4    Maes, M.5    Dantzer, R.6
  • 16
    • 0026582456 scopus 로고
    • In situ histochemical localization of type I interleukin-1 receptor messenger RNA in the central nervous system, pituitary, and adrenal gland of the mouse
    • Cunningham E.T., Wada E., Carter D.B., Tracey D.E., Battey J.F., De Souza E.B. In situ histochemical localization of type I interleukin-1 receptor messenger RNA in the central nervous system, pituitary, and adrenal gland of the mouse. Journal of Neuroscience 1992, 12:1101-1114.
    • (1992) Journal of Neuroscience , vol.12 , pp. 1101-1114
    • Cunningham, E.T.1    Wada, E.2    Carter, D.B.3    Tracey, D.E.4    Battey, J.F.5    De Souza, E.B.6
  • 18
    • 0024354977 scopus 로고
    • Stress and immunity: an integrated view of relationships between the brain and the immune system
    • Dantzer R., Kelley K.W. Stress and immunity: an integrated view of relationships between the brain and the immune system. Life Sciences 1989, 44:1995-2008.
    • (1989) Life Sciences , vol.44 , pp. 1995-2008
    • Dantzer, R.1    Kelley, K.W.2
  • 20
    • 79951960581 scopus 로고    scopus 로고
    • Inflammation-associated depression: from serotonin to kynurenine. Psychoneuroendocrinology., doi:10.1016/j.psyneuen.2010.09.012
    • Dantzer, R., O'Connor, J.C., Lawson, M.A., Kelley, K.W., 2010. Inflammation-associated depression: from serotonin to kynurenine. Psychoneuroendocrinology. doi:10.1016/j.psyneuen.2010.09.012.
    • (2010)
    • Dantzer, R.1    O'Connor, J.C.2    Lawson, M.A.3    Kelley, K.W.4
  • 21
    • 22044442141 scopus 로고    scopus 로고
    • Effects of interleukin-1 and endotoxin in the forced swim and tail suspension tests in mice
    • Dunn A.J., Swiergiel A.H. Effects of interleukin-1 and endotoxin in the forced swim and tail suspension tests in mice. Pharmacology, Biochemistry, and Behavior 2005, 81:688-693.
    • (2005) Pharmacology, Biochemistry, and Behavior , vol.81 , pp. 688-693
    • Dunn, A.J.1    Swiergiel, A.H.2
  • 24
  • 26
    • 0029833987 scopus 로고    scopus 로고
    • Dual expression of p80 type I and p68 type II interleukin-I receptors on anterior pituitary cells synthesizing growth hormone
    • French R.A., Zachary J.F., Dantzer R., Frawley L.S., Chizzonite R., Parnet P., Kelley K.W. Dual expression of p80 type I and p68 type II interleukin-I receptors on anterior pituitary cells synthesizing growth hormone. Endocrinology 1996, 137:4027-4036.
    • (1996) Endocrinology , vol.137 , pp. 4027-4036
    • French, R.A.1    Zachary, J.F.2    Dantzer, R.3    Frawley, L.S.4    Chizzonite, R.5    Parnet, P.6    Kelley, K.W.7
  • 27
    • 34248581135 scopus 로고    scopus 로고
    • Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior
    • Frenois F., Moreau M., O'Connor J.C., Lawson M., Micon C., Lestage J., Kelley K.W., Dantzer R., Castanon N. Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior. Psychoneuroendocrinology 2007, 32:516-531.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 516-531
    • Frenois, F.1    Moreau, M.2    O'Connor, J.C.3    Lawson, M.4    Micon, C.5    Lestage, J.6    Kelley, K.W.7    Dantzer, R.8    Castanon, N.9
  • 28
    • 0024994054 scopus 로고
    • Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms. Journal of Acquired Immune Deficiency Syndromes., 1999
    • Fuchs, D., Moller, A.A., Reibnegger, G., Stockle, E., Werner, E.R., Wachter, H., 1990. Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms. Journal of Acquired Immune Deficiency Syndromes (1999) 3, 873-876.
    • (1990) , Issue.3 , pp. 873-876
    • Fuchs, D.1    Moller, A.A.2    Reibnegger, G.3    Stockle, E.4    Werner, E.R.5    Wachter, H.6
  • 32
    • 45549084470 scopus 로고    scopus 로고
    • Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression
    • Goshen I., Kreisel T., Ben-Menachem-Zidon O., Licht T., Weidenfeld J., Ben-Hur T., Yirmiya R. Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression. Molecular Psychiatry 2008, 13:717-728.
    • (2008) Molecular Psychiatry , vol.13 , pp. 717-728
    • Goshen, I.1    Kreisel, T.2    Ben-Menachem-Zidon, O.3    Licht, T.4    Weidenfeld, J.5    Ben-Hur, T.6    Yirmiya, R.7
  • 33
    • 68049131222 scopus 로고    scopus 로고
    • Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity
    • Harrison N.A., Brydon L., Walker C., Gray M.A., Steptoe A., Critchley H.D. Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity. Biological Psychiatry 2009, 66:407-414.
    • (2009) Biological Psychiatry , vol.66 , pp. 407-414
    • Harrison, N.A.1    Brydon, L.2    Walker, C.3    Gray, M.A.4    Steptoe, A.5    Critchley, H.D.6
  • 35
    • 0024159821 scopus 로고
    • Biological basis of the behavior of sick animals
    • Hart B.L. Biological basis of the behavior of sick animals. Neuroscience and Biobehavioral Reviews 1988, 12:123-137.
    • (1988) Neuroscience and Biobehavioral Reviews , vol.12 , pp. 123-137
    • Hart, B.L.1
  • 36
    • 41349093774 scopus 로고    scopus 로고
    • Increased MCP-1 and microglia in various regions of the human alcoholic brain
    • He J., Crews F.T. Increased MCP-1 and microglia in various regions of the human alcoholic brain. Experimental Neurology 2008, 210:349-358.
    • (2008) Experimental Neurology , vol.210 , pp. 349-358
    • He, J.1    Crews, F.T.2
  • 37
    • 58149131466 scopus 로고    scopus 로고
    • Abstinence from moderate alcohol self-administration alters progenitor cell proliferation and differentiation in multiple brain regions of male and female P rats
    • He J., Overstreet D.H., Crews F.T. Abstinence from moderate alcohol self-administration alters progenitor cell proliferation and differentiation in multiple brain regions of male and female P rats. Alcoholism, Clinical and Experimental Research 2009, 33:129-138.
    • (2009) Alcoholism, Clinical and Experimental Research , vol.33 , pp. 129-138
    • He, J.1    Overstreet, D.H.2    Crews, F.T.3
  • 39
    • 77954175102 scopus 로고    scopus 로고
    • HMGB1, a potent proinflammatory cytokine in sepsis
    • Huang W., Tang Y., Li L. HMGB1, a potent proinflammatory cytokine in sepsis. Cytokine 2010, 51:119-126.
    • (2010) Cytokine , vol.51 , pp. 119-126
    • Huang, W.1    Tang, Y.2    Li, L.3
  • 40
    • 67449091270 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonism normalizes rapid eye movement sleep in alcohol dependence
    • Irwin M.R., Olmstead R., Valladares E.M., Breen E.C., Ehlers C.L. Tumor necrosis factor antagonism normalizes rapid eye movement sleep in alcohol dependence. Biological Psychiatry 2009, 66:191-195.
    • (2009) Biological Psychiatry , vol.66 , pp. 191-195
    • Irwin, M.R.1    Olmstead, R.2    Valladares, E.M.3    Breen, E.C.4    Ehlers, C.L.5
  • 41
    • 34047190418 scopus 로고    scopus 로고
    • Depressive disorders and immunity: 20 years of progress and discovery
    • Irwin M.F., Miller A.H. Depressive disorders and immunity: 20 years of progress and discovery. Brain, Behavior, and Immunity 2007, 21:374-383.
    • (2007) Brain, Behavior, and Immunity , vol.21 , pp. 374-383
    • Irwin, M.F.1    Miller, A.H.2
  • 42
    • 1842585666 scopus 로고    scopus 로고
    • Disordered sleep, nocturnal cytokines, and immunity: interactions between alcohol dependence and African-American ethnicity
    • Irwin M.R., Rinetti G. Disordered sleep, nocturnal cytokines, and immunity: interactions between alcohol dependence and African-American ethnicity. Alcohol (Fayetteville, NY) 2004, 32:53-61.
    • (2004) Alcohol (Fayetteville, NY) , vol.32 , pp. 53-61
    • Irwin, M.R.1    Rinetti, G.2
  • 44
    • 0024064663 scopus 로고
    • Cross-talk between the immune and endocrine systems
    • Kelley K.W. Cross-talk between the immune and endocrine systems. Journal of Animal Science 1988, 66:2095-2108.
    • (1988) Journal of Animal Science , vol.66 , pp. 2095-2108
    • Kelley, K.W.1
  • 45
    • 84929559246 scopus 로고    scopus 로고
    • Inflammation and behavior
    • Oxford University Press, Oxford, New York, G.E. Demas, R.J. Nelson (Eds.)
    • Kelley K.W., Aubert A., Dantzer R. Inflammation and behavior. Eco-Immunology and Behavior 2011, Oxford University Press, Oxford, New York. G.E. Demas, R.J. Nelson (Eds.).
    • (2011) Eco-Immunology and Behavior
    • Kelley, K.W.1    Aubert, A.2    Dantzer, R.3
  • 49
    • 0028063052 scopus 로고
    • Reduction in food and water intake induced by microinjection of interleukin-1 beta in the ventromedial hypothalamus of the rat
    • Kent S., Rodriguez F., Kelley K.W., Dantzer R. Reduction in food and water intake induced by microinjection of interleukin-1 beta in the ventromedial hypothalamus of the rat. Physiology & Behavior 1994, 56:1031-1036.
    • (1994) Physiology & Behavior , vol.56 , pp. 1031-1036
    • Kent, S.1    Rodriguez, F.2    Kelley, K.W.3    Dantzer, R.4
  • 53
    • 0014682651 scopus 로고
    • Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect
    • Lapin I.P., Oxenkrug G.F. Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect. Lancet 1969, 293:132-136.
    • (1969) Lancet , vol.293 , pp. 132-136
    • Lapin, I.P.1    Oxenkrug, G.F.2
  • 54
    • 77949571369 scopus 로고    scopus 로고
    • Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression
    • Laugeray A., Launay J.M., Callebert J., Surget A., Belzung C., Barone P.R. Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression. Behavioural Brain Research 2010, 210:84-91.
    • (2010) Behavioural Brain Research , vol.210 , pp. 84-91
    • Laugeray, A.1    Launay, J.M.2    Callebert, J.3    Surget, A.4    Belzung, C.5    Barone, P.R.6
  • 55
    • 0036429151 scopus 로고    scopus 로고
    • The enzyme indoleamine 2, 3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen
    • Lestage J., Verrier D., Palin K., Dantzer R. The enzyme indoleamine 2, 3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen. Brain, Behavior, and Immunity 2002, 16:596-601.
    • (2002) Brain, Behavior, and Immunity , vol.16 , pp. 596-601
    • Lestage, J.1    Verrier, D.2    Palin, K.3    Dantzer, R.4
  • 58
    • 0028950478 scopus 로고
    • The monocyte-T-lymphocyte hypothesis of major depression
    • Maes M., Smith R., Scharpe S. The monocyte-T-lymphocyte hypothesis of major depression. Psychoneuroendocrinology 1995, 20:111-116.
    • (1995) Psychoneuroendocrinology , vol.20 , pp. 111-116
    • Maes, M.1    Smith, R.2    Scharpe, S.3
  • 59
  • 60
    • 70450201440 scopus 로고    scopus 로고
    • The role of Toll-like receptors in perinatal brain injury.
    • Clinics in Perinatology
    • Mallard, C., Wang, X., Hagberg, H., 2009. The role of Toll-like receptors in perinatal brain injury. Clinics in Perinatology 36, 763-772 (v-vi).
    • (2009) , vol.5-6 , Issue.36 , pp. 763-772
    • Mallard, C.1    Wang, X.2    Hagberg, H.3
  • 62
    • 58549087919 scopus 로고    scopus 로고
    • Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface
    • Miller A.H. Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface. Brain, Behavior, and Immunity 2009, 23:149-158.
    • (2009) Brain, Behavior, and Immunity , vol.23 , pp. 149-158
    • Miller, A.H.1
  • 68
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler E.J., Hyman S.E. Animal models of neuropsychiatric disorders. Nature Neuroscience 2010, 13:1161-1169.
    • (2010) Nature Neuroscience , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 69
    • 77950020374 scopus 로고    scopus 로고
    • Stress and IL-1beta contribute to the development of depressive-like behavior following peripheral nerve injury
    • Norman G.J., Karelina K., Zhang N., Walton J.C., Morris J.S., Devries A.C. Stress and IL-1beta contribute to the development of depressive-like behavior following peripheral nerve injury. Molecular Psychiatry 2010, 15:404-414.
    • (2010) Molecular Psychiatry , vol.15 , pp. 404-414
    • Norman, G.J.1    Karelina, K.2    Zhang, N.3    Walton, J.C.4    Morris, J.S.5    Devries, A.C.6
  • 70
    • 65249156122 scopus 로고    scopus 로고
    • Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2, 3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin
    • O'Connor J.C., Andre C., Wang Y., Lawson M.A., Szegedi S.S., Lestage J., Castanon N., Kelley K.W., Dantzer R. Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2, 3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin. Journal of Neuroscience 2009, 29:4200-4209.
    • (2009) Journal of Neuroscience , vol.29 , pp. 4200-4209
    • O'Connor, J.C.1    Andre, C.2    Wang, Y.3    Lawson, M.A.4    Szegedi, S.S.5    Lestage, J.6    Castanon, N.7    Kelley, K.W.8    Dantzer, R.9
  • 75
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: inflammation and the pathogenesis of depression
    • Raison C.L., Capuron L., Miller A.H. Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends in Immunology 2006, 27:24-31.
    • (2006) Trends in Immunology , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 76
    • 79955731840 scopus 로고    scopus 로고
    • CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Molecular Psychiatry.
    • Raison, C.L., Dantzer, R., Kelley, K.W., Lawson, M.A., Woolwine, B.J., Vogt, G., Spivey, J.R., Saito, K., Miller, A.H., 2009. CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Molecular Psychiatry.
    • (2009)
    • Raison, C.L.1    Dantzer, R.2    Kelley, K.W.3    Lawson, M.A.4    Woolwine, B.J.5    Vogt, G.6    Spivey, J.R.7    Saito, K.8    Miller, A.H.9
  • 77
    • 0023276493 scopus 로고
    • Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor
    • Sapolsky R., Rivier C., Yamamoto G., Plotsky P., Vale W. Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor. Science (New York, NY) 1987, 238:522-524.
    • (1987) Science (New York, NY) , vol.238 , pp. 522-524
    • Sapolsky, R.1    Rivier, C.2    Yamamoto, G.3    Plotsky, P.4    Vale, W.5
  • 79
    • 0025910497 scopus 로고
    • The macrophage theory of depression
    • Smith R.S. The macrophage theory of depression. Medical Hypotheses 1991, 35:298-306.
    • (1991) Medical Hypotheses , vol.35 , pp. 298-306
    • Smith, R.S.1
  • 80
    • 67649985942 scopus 로고    scopus 로고
    • Alcoholism: a systems approach from molecular physiology to addictive behavior
    • Spanagel R. Alcoholism: a systems approach from molecular physiology to addictive behavior. Physiological Reviews 2009, 89:649-705.
    • (2009) Physiological Reviews , vol.89 , pp. 649-705
    • Spanagel, R.1
  • 83
    • 8744309183 scopus 로고    scopus 로고
    • Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes
    • Valles S.L., Blanco A.M., Pascual M., Guerri C. Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes. Brain Pathology (Zurich, Switzerland) 2004, 14:365-371.
    • (2004) Brain Pathology (Zurich, Switzerland) , vol.14 , pp. 365-371
    • Valles, S.L.1    Blanco, A.M.2    Pascual, M.3    Guerri, C.4
  • 84
    • 0033656015 scopus 로고    scopus 로고
    • The pain of being sick: implications of immune-to-brain communication for understanding pain
    • Watkins L.R., Maier S.F. The pain of being sick: implications of immune-to-brain communication for understanding pain. Annual Review of Psychology 2000, 51:29-57.
    • (2000) Annual Review of Psychology , vol.51 , pp. 29-57
    • Watkins, L.R.1    Maier, S.F.2
  • 87
    • 0029962322 scopus 로고    scopus 로고
    • Endotoxin produces a depressive-like episode in rats
    • Yirmiya R. Endotoxin produces a depressive-like episode in rats. Brain Research 1996, 711:163-174.
    • (1996) Brain Research , vol.711 , pp. 163-174
    • Yirmiya, R.1
  • 88
    • 78651412528 scopus 로고    scopus 로고
    • Immune modulation of learning, memory, neural 816 plasticity and neurogenesis
    • Yirmiya R., Goshen I. Immune modulation of learning, memory, neural 816 plasticity and neurogenesis. Brain, Behavior, and Immunity 2011, 25:181-213.
    • (2011) Brain, Behavior, and Immunity , vol.25 , pp. 181-213
    • Yirmiya, R.1    Goshen, I.2


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