Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer

British Journal of Cancer

Volumn 110, Issue 5, 2014, Pages 1288-1297

  Yang, Q ^a   Zhang, F ^a   Ding, Y ^b   Huang, J ^a   Chen, S ^a   Wu, Q ^a   Wang, Z ^c,d   Chen, C ^a  

^a BENGBU MEDICAL COLLEGE   (China)

^b Branch of Tumour of the Center Hospital of Bengbu   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

^d THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Akt; Breast cancer; CXCR4; ERK1 2; Metastasis

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; FOCAL ADHESION KINASE; GST NT21MP; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLERIXAFOR; POLYPEPTIDE; PROTEIN BCL 2; PROTEIN KINASE B; STEROID RECEPTOR COACTIVATOR; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL ADHESION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR INVASION; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHEMOKINE CXCL2; DOWN-REGULATION; FEMALE; HUMANS; MCF-7 CELLS; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; PEPTIDES; RECEPTORS, CXCR4; RECOMBINANT PROTEINS;

EID: 84895820294     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.1     Document Type: Article

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