The CXCR4 Antagonist AMD3465 Regulates Oncogenic Signaling and Invasiveness In Vitro and Prevents Breast Cancer Growth and Metastasis In Vivo

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Ling, Xiaoyang ^a   Spaeth, Erika ^a   Chen, Ye ^a   Shi, Yuexi ^a   Zhang, Weiguo ^a   Schober, Wendy ^a   Hail, Numsen ^a   Konopleva, Marina ^a   Andreeff, Michael ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CHEMOKINE RECEPTOR CXCR4; GLYCOGEN SYNTHASE KINASE 3; JANUS KINASE 2; MYC PROTEIN; N [1,4,8,11 TETRAAZACYCLOTETRADECANYL 1,4 PHENYLENEBIS(METHYLENE)] 2 (AMINOMETHYL)PYRIDINE; PROTEIN KINASE B; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BREAST CANCER; BREAST METASTASIS; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL INFILTRATION; CELL INVASION; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LIVER METASTASIS; LUNG METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPLEEN; TUMOR MICROENVIRONMENT;

EID: 84874629395     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058426     Document Type: Article

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