Role of the CXCR4/CXCL12 signaling axis in breast cancer metastasis to the brain

Clinical and Experimental Metastasis

Volumn 27, Issue 2, 2010, Pages 97-105

  Hinton, Cimona V ^a,b   Avraham, Shalom ^a,b   Avraham, Hava Karsenty ^a,b  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

AKT; AMD3100; Breast cancer; CNS; CXCL12; CXCR4; Endothelial cells; HER2; Metastasis; PI 3K; VEGF

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; EPIDERMAL GROWTH FACTOR RECEPTOR 2; NEUROTROPHIN; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1; TRASTUZUMAB; VASCULOTROPIN; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ANTINEOPLASTIC ACTIVITY; BRAIN METASTASIS; BREAST CANCER; CANCER GROWTH; CANCER RISK; CARCINOGENESIS; CELL MIGRATION; HUMAN; INTRACRANIAL TUMOR; LUNG METASTASIS; NONHUMAN; PROGNOSIS; PROTEIN FUNCTION; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; BRAIN TUMOR; BREAST TUMOR; FEMALE; METABOLISM; METASTASIS; PATHOLOGY; PHYSIOLOGY;

BRAIN NEOPLASMS; BREAST NEOPLASMS; CHEMOKINE CXCL12; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION;

EID: 77949890714     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-008-9210-2     Document Type: Review

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