The amyloid precursor protein intracellular domain (AICD) disrupts actin dynamics and mitochondrial bioenergetics

Journal of Neurochemistry

Volumn 113, Issue 1, 2010, Pages 275-284

  Ward, Manus W ^a   Concannon, Caoimhín G ^a   Whyte, Jacqueline ^a   Walsh, Ciara M ^a   Corley, Brian ^a   Prehn, Jochen H M ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

Alzheimer's disease; APP intracellular domain; Mitochondrial membrane potential; Superoxide; Transgelin

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE; AMYLOID PRECURSOR PROTEIN; SUPEROXIDE; TRANSGELIN;

ACTIN FILAMENT; ALZHEIMER DISEASE; ARTICLE; BIOENERGY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MORPHOLOGY; NERVE CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROCESSING; PROTEIN STABILITY;

ACTINS; ADENOSINE TRIPHOSPHATE; AMYLOID BETA-PROTEIN PRECURSOR; CELL LINE, TUMOR; DOXYCYCLINE; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; RHODAMINES; RNA, SMALL INTERFERING; STATISTICS, NONPARAMETRIC; SUPEROXIDES; TRANSFECTION;

EID: 77749258539     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06615.x     Document Type: Article

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