Evolutionary perspectives on the links between mitochondrial genotype and disease phenotype

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 4, 2014, Pages 1393-1403

  Dowling, Damian K ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Adaptation; Heteroplasmy; Male health; Mitochondrial disease; Mitochondrial genome evolution; Mitochondrion

Indexed keywords

MITOCHONDRIAL DNA;

ALLELE; CELL NUCLEUS; DISEASE ASSOCIATION; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA SEQUENCE; EXTRACHROMOSOMAL INHERITANCE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOIDY; HETEROPLASMY; HUMAN; MITOCHONDRIAL GENETICS; MITOCHONDRIAL GENOME; MITOCHONDRIAL RESPIRATION; MOLECULAR EVOLUTION; MUTATION RATE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REVIEW;

ADAPTATION; HETEROPLASMY; MALE HEALTH; MITOCHONDRIAL DISEASE; MITOCHONDRIAL GENOME EVOLUTION; MITOCHONDRION;

ANIMALS; DNA, MITOCHONDRIAL; EVOLUTION, MOLECULAR; FEMALE; GENETIC ASSOCIATION STUDIES; GENOTYPE; HUMANS; MALE; MITOCHONDRIAL DISEASES; PHENOTYPE;

EID: 84895516213     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.11.013     Document Type: Review

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