Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Kenney, M Cristina ^a   Chwa, Marilyn ^a   Atilano, Shari R ^a   Pavlis, Janelle M ^a   Falatoonzadeh, Payam ^a   Ramirez, Claudio ^a   Malik, Deepika ^a   Hsu, Tiffany ^a   Woo, Grace ^a   Soe, Kyaw ^a   Nesburn, Anthony B ^a,b   Boyer, David S ^c   Kuppermann, Baruch D ^a   Jazwinski, S Michal ^d   Miceli, Michael V ^d   Wallace, Douglas C ^e   Udar, Nitin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c RETINA VITREOUS ASSOCIATES MEDICAL GROUP   (United States)

^d TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

ARTICLE; C3 GENE; CELL FUNCTION; CELL GROWTH; CELL METABOLISM; CFH GENE; CONTROLLED STUDY; CYBRID; DOWN REGULATION; EFEMP1 GENE; ENERGY YIELD; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC ASSOCIATION; GROWTH RATE; HAPLOTYPE; HIGH RISK PATIENT; HUMAN; HUMAN CELL; MYO7A; PIGMENT EPITHELIUM; POLYMERASE CHAIN REACTION; RETINA DEGENERATION; RETINA MACULA AGE RELATED DEGENERATION; SIGNAL TRANSDUCTION; USHER SYNDROME;

ADENOSINE TRIPHOSPHATE; CELLS, CULTURED; COMPLEMENT C3; COMPLEMENT FACTOR H; DNA, MITOCHONDRIAL; EPITHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION; HAPLOTYPES; HUMANS; HYBRID CELLS; LACTIC ACID; MACULAR DEGENERATION; MITOCHONDRIA; MODELS, BIOLOGICAL; MYOSINS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION;

EID: 84872856132     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054339     Document Type: Article

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