Comparing phylogeny and the predicted pathogenicity of protein variations reveals equal purifying selection across the global human mtDNA diversity

American Journal of Human Genetics

Volumn 88, Issue 4, 2011, Pages 433-439

  Pereira, Luísa ^a,b   Soares, Pedro ^a   Radivojac, Predrag ^c   Li, Biao ^c   Samuels, David C ^d  

^a UNIVERSITY OF PORTO   (Portugal)

^b University of Porto   (Portugal)

^c INDIANA UNIVERSITY   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; MITOCHONDRIAL DNA;

ARTICLE; GENETIC VARIABILITY; HUMAN; MOLECULAR PHYLOGENY; PATHOGENICITY; PHYLOGENETIC TREE; PRIORITY JOURNAL; PROTEIN VARIANT;

AMINO ACID SUBSTITUTION; DNA, MITOCHONDRIAL; EVOLUTION, MOLECULAR; FEMALE; GENES, MITOCHONDRIAL; GENETIC VARIATION; HUMANS; MALE; MITOCHONDRIAL PROTEINS; MUTATION; PHYLOGENY; SELECTION, GENETIC;

EID: 79953706954     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2011.03.006     Document Type: Article

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