Sulindac compounds facilitate the cytotoxicity of β-lapachone by up-regulation of NAD(P)H quinone oxidoreductase in human lung cancer cells

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Kung, Hsiu Ni ^a   Weng, Tsai Yun ^b   Liu, Yu Lin ^b   Lu, Kuo Shyan ^a   Chau, Yat Pang ^b,c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c MACKAY MEDICAL COLLEGE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LAPACHONE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); STRESS ACTIVATED PROTEIN KINASE; SULINDAC; SULINDAC SULFIDE; SULINDAC SULFONE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG CANCER; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ADENOCARCINOMA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SYNERGISM; HUMANS; LUNG NEOPLASMS; NAD(P)H DEHYDROGENASE (QUINONE); NAPHTHOQUINONES; SULINDAC; UP-REGULATION;

EID: 84895515192     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088122     Document Type: Article

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