β-Lapachone-induced reactive oxygen species (ROS) generation mediates autophagic cell death in glioma U87 MG cells

Chemico-Biological Interactions

Volumn 189, Issue 1-2, 2011, Pages 37-44

  Park, Eun Jung ^a   Choi, Kyeong Sook ^b   Kwon, Taeg Kyu ^a  

^a Keimyung University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

Author keywords

Lapachone; Autophagic cell death; Autophagy; Reactive oxygen species (ROS); U87 MG

Indexed keywords

BECLIN 1; BETA LAPACHONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL ORGANELLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG RESPONSE; GENE EXPRESSION; GLIOMA CELL; PROTEIN PROCESSING; PROTEIN TRANSPORT;

ADENINE; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME INHIBITORS; FLOW CYTOMETRY; GLIOMA; HUMANS; MACROLIDES; MICROSCOPY, FLUORESCENCE; NAD(P)H DEHYDROGENASE (QUINONE); NAPHTHOQUINONES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

EID: 79251605988     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.10.013     Document Type: Article

References (28)

1. T. Yorimitsu, and D.J. Klionsky Autophagy: molecular machinery for self-eating Cell Death Differ. 12 2005 1542 1552
2. A.J. Meijer, and P. Codogno Regulation and role of autophagy in mammalian cells Int. J. Biochem. Cell Biol. 36 2004 2445 2462
3. G. Mariño, and C. López-Otín Autophagy: molecular mechanisms, physiological functions and relevance in human pathology Cell Mol. Life Sci. 61 2004 1439 1454
4. E.H. Baehrecke Autophagy: dual roles in life and death? Nat. Rev. Mol. Cell. Biol. 6 2005 505 510
5. K. Schaffner-Sabba, K.H. Schmidt-Ruppin, W. Wehrli, A.R. Schuerch, and J.W. Wasley β-Lapachone: synthesis of derivatives and activities in tumor models J. Med. Chem. 27 1984 990 994
6. D.A. Boothman, S. Greer, and A.B. Pardee Potentiation of halogenated pyrimidine radiosensitizers in human carcinoma cells by beta-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione), a novel DNA repair inhibitor Cancer Res. 47 1987 5361 5366
7. E.A. Bey, M.S. Bentle, K.E. Reinicke, Y. Dong, C.R. Yang, L. Girard, J.D. Minna, W.G. Bornmann, J. Gao, and D.A. Boothman An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone Proc. Natl. Acad. Sci. U.S.A. 104 2007 11832 11837
8. J.J. Pink, S.M. Planchon, C. Tagliarino, M.E. Varnes, D. Siegel, and D.A. Boothman NAD(P)H:quinone oxidoreductase activity is the principal determinant of betalapachone cytotoxicity J. Biol. Chem. 275 2000 5416 5424
9. A.B. Pardee, Y.Z. Li, and C. Li Cancer therapy with b-lapachone Curr. Cancer Drug Targets 2 2002 227 242
10. H.J. Woo, K.Y. Park, C.H. Rhu, W.H. Lee, B.T. Choi, G.Y. Kim, Y.M. Park, and Y.H. Choi Beta-lapachone, a quinone isolated from Tabebuia avellanedae, induces apoptosis in HepG2 hepatoma cell line through induction of Bax and activation of caspase J. Med. Food. 9 2006 161 168
11. Y.C. Lien, H.N. Kung, K.S. Lu, C.J. Jeng, and Y.P. Chau Involvement of endoplasmic reticulum stress and activation of MAP kinases in beta-lapachone-induced human prostate cancer cell apoptosis Histol. Histopathol. 23 2008 1299 1308
12. D.A. Scudiero, R.H. Shoemaker, K.D. Paull, A. Monks, S. Tierney, T.H. Nofziger, M.J. Currens, D. Seniff, and M.R. Boyd Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines Cancer Res. 48 1988 4827 4833
13. C. Korzeniewski, and D.M. Callewaert An enzyme-release assay for natural cytotoxicity J. Immunol. Methods 64 1983 313 320
14. C.P. LeBel, H. Ischiropoulos, and C.C. Bondy Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress Chem. Res. Toxicol. 5 1992 227 231
15. N. Mizushima Methods for monitoring autophagy Int. J. Biochem. Cell Biol. 36 2004 2491 2502
16. W. Martinet, G.R. De Meyer, L. Andries, A.G. Herman, and M.M. Kockx In situ detection of starvation-induced autophagy J. Histochem. Cytochem. 54 2006 85 96
17. I. Tanida, T. Ueno, and E. Kominami LC3 and autophagy Methods Mol. Biol. 445 2008 77 88
18. N. Mizushima, and T. Yoshimori How to interpret LC3 immunoblotting Autophagy 3 2007 542 545
19. S. Paglin, T. Hollister, T. Delohery, N. Hackett, M. McMahill, E. Sphicas, D. Domingo, and J. Yahalom A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles Cancer Res. 61 2001 439 444
20. P.O. Seglen, and P.B. Gordon 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes Proc. Natl. Acad. Sci. U.S.A. 79 1982 1889 1892
21. A. Petiot, E. Ogier-Denis, E.F. Blommaart, A.J. Meijer, and P. Codogno Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells J. Biol. Chem. 275 2000 992 998
22. M. Høyer-Hansen, and M. Jäättelä Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium Cell Death Differ. 14 2007 1576 1582 (Pubitemid 47278843)
23. S. Yasuhara, A. Asai, N.D. Sahani, and J.A. Martyn Mitochondria, endoplasmic reticulum, and alternative pathways of cell death in critical illness Crit. Care Med. 35 2007 S488 S495
24. Y. Chen, E. McMillan-Ward, J. Kong, S.J. Israels, and S.B. Gibson Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells Cell Death Differ. 15 2008 171 182
25. L. Yu, F. Wan, S. Dutta, S. Welsh, Z. Liu, E. Freundt, E.H. Baehrecke, and M. Lenardo Autophagic programmed cell death by selective catalase degradation Proc. Natl. Acad. Sci. U.S.A. 103 2006 4952 4957
26. R. Scherz-Shouval, E. Shvets, E. Fass, H. Shorer, L. Gil, and Z. Elazar Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 EMBO J. 26 2007 1749 1760
27. S.M. Planchon, J.J. Pink, C. Tagliarino, W.G. Bornmann, M.E. Varnes, and D.A. Boothman beta-Lapachone-induced apoptosis in human prostate cancer cells: involvement of NQO1/xip3 Exp. Cell Res. 276 2001 95 106
28. C. Tagliarino, J.J. Pink, K.E. Reinicke, S.M. Simmers, S.M. Wuerzberger-Davis, and D.A. Boothman Mu-calpain activation in beta-lapachone-mediated apoptosis Cancer Biol. Ther. 2 2003 141 152