Quinone reductase inhibitors block SAPK/JNK and NFκB pathways and potentiate apoptosis

Journal of Biological Chemistry

Volumn 274, Issue 44, 1999, Pages 31150-31154

  Cross, Janet V ^c   Deak, Joseph C ^c   Rich, Elizabeth A ^a   Qian, Yongyi ^c   Lewis, Margaret ^c   Parrott, Louis A ^c   Mochida, Keiko ^a   Gustafson, Daniel ^b   Pol, Scott Vande ^c   Templeton, Dennis J ^c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

DICOUMAROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); STRESS ACTIVATED PROTEIN KINASE; THIOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONCENTRATION (PARAMETERS); ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; STRESS;

APOPTOSIS; CELLS, CULTURED; DICUMAROL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME ACTIVATION; HUMANS; HYDROQUINONES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY; LEUKOCYTES, MONONUCLEAR; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NAD(P)H DEHYDROGENASE (QUINONE); NF-KAPPA B; OSMOTIC PRESSURE; OXIDATION-REDUCTION; PHYTOHEMAGGLUTININS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033615539     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.44.31150     Document Type: Article

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