Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response

Cell Death and Differentiation

Volumn 9, Issue 12, 2002, Pages 1352-1359

  Gatti, L ^a   Supino, R ^a   Perego, P ^a   Pavesi, R ^a   Caserini, C ^a   Carenini, N ^a   Righetti, S C ^a   Zuco, V ^a   Zunino, F ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Apoptosis; Cell cycle arrest; p53 phosphorylation; Platinum complex

Indexed keywords

BBR 3464; CISPLATIN; PLATINUM DERIVATIVE; PROTEIN BAX; PROTEIN P21; PROTEIN P53; SERINE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOSTASIS; DNA DAMAGE; DNA REPAIR; DOWN REGULATION; DRUG DNA BINDING; GENETIC TRANSFECTION; GENOTOXICITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL DIVISION; CISPLATIN; CYTOTOXINS; DNA DAMAGE; HUMANS; NEOPLASMS; PHOSPHORYLATION; PLATINUM COMPOUNDS; SERINE; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036952664     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401109     Document Type: Article

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