-
1
-
-
2642586416
-
Chromosomal aberrations and risk of cancer in humans: an epidemiological perspective
-
Bonassi S., Znaor A., Norppa H., and Hagmar L. Chromosomal aberrations and risk of cancer in humans: an epidemiological perspective. Cytogen. Genome Res. 104 (2004) 376-382
-
(2004)
Cytogen. Genome Res.
, vol.104
, pp. 376-382
-
-
Bonassi, S.1
Znaor, A.2
Norppa, H.3
Hagmar, L.4
-
2
-
-
29844458539
-
Children's exposure to environmental pollutants and biomarkers of genetic damage, II. Results of a comprehensive literature search and meta-analysis
-
Neri M., Ugolini D., Bonassi S., Fucic A., Holland N., Knudsen L.E., Sram R.J., Ceppi M., Bocchini V., and Merlo D.F. Children's exposure to environmental pollutants and biomarkers of genetic damage, II. Results of a comprehensive literature search and meta-analysis. Mutat. Res. 612 (2006) 14-39
-
(2006)
Mutat. Res.
, vol.612
, pp. 14-39
-
-
Neri, M.1
Ugolini, D.2
Bonassi, S.3
Fucic, A.4
Holland, N.5
Knudsen, L.E.6
Sram, R.J.7
Ceppi, M.8
Bocchini, V.9
Merlo, D.F.10
-
3
-
-
0037182151
-
A protocol for the in vitro micronucleus test. I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity
-
Garriott M.L., Phelps J.B., and Hoffman W.P. A protocol for the in vitro micronucleus test. I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity. Mutat. Res. 517 (2002) 123-134
-
(2002)
Mutat. Res.
, vol.517
, pp. 123-134
-
-
Garriott, M.L.1
Phelps, J.B.2
Hoffman, W.P.3
-
4
-
-
0037180357
-
A protocol for the in vitro micronucleus test. II. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 10 chemicals with different mechanisms of action and different levels of activity
-
Phelps B.J., Garriott M.L., and Hoffman W.P. A protocol for the in vitro micronucleus test. II. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 10 chemicals with different mechanisms of action and different levels of activity. Mutat. Res. 521 (2002) 103-112
-
(2002)
Mutat. Res.
, vol.521
, pp. 103-112
-
-
Phelps, B.J.1
Garriott, M.L.2
Hoffman, W.P.3
-
5
-
-
33745862394
-
SFTG international collaborative study on in vitro micronucleus test. I. General conditions and overall conclusions of the study
-
Lorge E., Thybaud V., Aardema M.J., Oliver J., Wakata A., Lorenzon G., and Marzin D. SFTG international collaborative study on in vitro micronucleus test. I. General conditions and overall conclusions of the study. Mutat. Res. 607 (2006) 13-36
-
(2006)
Mutat. Res.
, vol.607
, pp. 13-36
-
-
Lorge, E.1
Thybaud, V.2
Aardema, M.J.3
Oliver, J.4
Wakata, A.5
Lorenzon, G.6
Marzin, D.7
-
6
-
-
18344377030
-
The p53 pathway: positive and negative feedback loops
-
Harris S.L., and Levine A.J. The p53 pathway: positive and negative feedback loops. Oncogene 24 (2005) 2899-2908
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
7
-
-
0037459377
-
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
-
Leng R.P., Lin Y., Ma W., Wu H., Lemmers B., Chung S., Parant J.M., Lozano G., Hakem R., and Benchimol S. Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 21 (2003) 779-789
-
(2003)
Cell
, vol.21
, pp. 779-789
-
-
Leng, R.P.1
Lin, Y.2
Ma, W.3
Wu, H.4
Lemmers, B.5
Chung, S.6
Parant, J.M.7
Lozano, G.8
Hakem, R.9
Benchimol, S.10
-
8
-
-
0037329056
-
The p53-Mdm2 module and the ubiquitin system
-
Michael D., and Oren M. The p53-Mdm2 module and the ubiquitin system. Semin. Cancer Biol. 13 (2003) 49-58
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 49-58
-
-
Michael, D.1
Oren, M.2
-
9
-
-
2342447397
-
The ubiquitin ligase COP1 is a critical negative regulator of p53
-
Dornan D., Wertz I., Shimizu H., Arnott D., Frantz G.D., Dowd P., O'Rourke K., Koeppen H., and Dixit V.M. The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 429 (2004) 86-92
-
(2004)
Nature
, vol.429
, pp. 86-92
-
-
Dornan, D.1
Wertz, I.2
Shimizu, H.3
Arnott, D.4
Frantz, G.D.5
Dowd, P.6
O'Rourke, K.7
Koeppen, H.8
Dixit, V.M.9
-
10
-
-
0028286420
-
Nuclear accumulation of p53 in response to treatment with DNA-damaging agents
-
Hess R., Plaumann B., Lutum A., Haessler S., Heinz C., Fritsche B., and Brandner G. Nuclear accumulation of p53 in response to treatment with DNA-damaging agents. Toxicol. Lett. 72 (1994) 43-52
-
(1994)
Toxicol. Lett.
, vol.72
, pp. 43-52
-
-
Hess, R.1
Plaumann, B.2
Lutum, A.3
Haessler, S.4
Heinz, C.5
Fritsche, B.6
Brandner, G.7
-
11
-
-
0037737758
-
Regulation of p53 responses by post-translational modifications
-
Xu Y. Regulation of p53 responses by post-translational modifications. Cell Death Differ. 10 (2003) 400-403
-
(2003)
Cell Death Differ.
, vol.10
, pp. 400-403
-
-
Xu, Y.1
-
12
-
-
0031926177
-
A new approach to identifying genotoxic carcinogens: p53 induction as an indicator of genotoxic damage
-
Yang J., and Duerksen-Hughes P. A new approach to identifying genotoxic carcinogens: p53 induction as an indicator of genotoxic damage. Carcinogenesis 19 (1998) 1117-1125
-
(1998)
Carcinogenesis
, vol.19
, pp. 1117-1125
-
-
Yang, J.1
Duerksen-Hughes, P.2
-
13
-
-
0032694761
-
p53 induction as a genotoxic test for twenty-five chemicals undergoing in vivo carcinogenicity testing
-
Duerksen-Hughes J.P., Yang J., and Ozcan O. p53 induction as a genotoxic test for twenty-five chemicals undergoing in vivo carcinogenicity testing. Environ. Health Perspect. 107 (1999) 805-812
-
(1999)
Environ. Health Perspect.
, vol.107
, pp. 805-812
-
-
Duerksen-Hughes, J.P.1
Yang, J.2
Ozcan, O.3
-
14
-
-
0037350049
-
Inorganic and dimethylated arsenic species induce cellular p53
-
Filippova M., and Duerksen-Hughes P.J. Inorganic and dimethylated arsenic species induce cellular p53. Chem. Res. Toxicol. 16 (2003) 423-431
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 423-431
-
-
Filippova, M.1
Duerksen-Hughes, P.J.2
-
15
-
-
33745821240
-
SFTG international collaborative study on in vitro micronucleus test. IV. Using CHL cells
-
Wakata A., Matsuoka K., Yamakage J., Yoshida K., Kubo K., Kobayashi N., Senjyu S., Itoh H., Miyajima S., Hamada S., Nishida H., Araki E., Yamamura A., Matsui V., Thybaud G., Lorenzon D., Marzin E., and Lorge. SFTG international collaborative study on in vitro micronucleus test. IV. Using CHL cells. Mutat. Res. 607 (2006) 88-124
-
(2006)
Mutat. Res.
, vol.607
, pp. 88-124
-
-
Wakata, A.1
Matsuoka, K.2
Yamakage, J.3
Yoshida, K.4
Kubo, K.5
Kobayashi, N.6
Senjyu, S.7
Itoh, H.8
Miyajima, S.9
Hamada, S.10
Nishida, H.11
Araki, E.12
Yamamura, A.13
Matsui, V.14
Thybaud, G.15
Lorenzon, D.16
Marzin, E.17
Lorge18
-
16
-
-
0035023346
-
In vitro effects of albendazole and its metabolites on the cell proliferation kinetics and micronuclei frequency of stimulated human lymphocytes
-
Ramirez T., Benitez-Bribiesca L., Ostrosky-Wegman P., and Herrera L.A. In vitro effects of albendazole and its metabolites on the cell proliferation kinetics and micronuclei frequency of stimulated human lymphocytes. Arch. Med. Res. 32 (2001) 119-122
-
(2001)
Arch. Med. Res.
, vol.32
, pp. 119-122
-
-
Ramirez, T.1
Benitez-Bribiesca, L.2
Ostrosky-Wegman, P.3
Herrera, L.A.4
-
17
-
-
0036858676
-
Detection and characterization of mechanisms of action of aneugenic chemicals
-
Parry E.M., Parry J.M., Corso C., Doherty A., Haddad F., Hermine T.F., Johonson G., Kayani M., Quick E., Warr T., and Williamson J. Detection and characterization of mechanisms of action of aneugenic chemicals. Mutagenesis 17 (2002) 509-521
-
(2002)
Mutagenesis
, vol.17
, pp. 509-521
-
-
Parry, E.M.1
Parry, J.M.2
Corso, C.3
Doherty, A.4
Haddad, F.5
Hermine, T.F.6
Johonson, G.7
Kayani, M.8
Quick, E.9
Warr, T.10
Williamson, J.11
-
18
-
-
0027497435
-
The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations
-
Fenech M. The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations. Mutat. Res. 285 (1993) 35-44
-
(1993)
Mutat. Res.
, vol.285
, pp. 35-44
-
-
Fenech, M.1
-
19
-
-
0037427878
-
HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures
-
Fenech M., Chang W.P., Kirsch-Volders M., Holland N., Bonassi S., and Zeiger E. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat. Res. 534 (2003) 65-75
-
(2003)
Mutat. Res.
, vol.534
, pp. 65-75
-
-
Fenech, M.1
Chang, W.P.2
Kirsch-Volders, M.3
Holland, N.4
Bonassi, S.5
Zeiger, E.6
-
20
-
-
0031589701
-
Induction of p53 protein expression by sodium arsenite
-
Salazar A.M., Ostrosky-Wegman P., Menendez D., Miranda E., Garcia-Carranca A., and Rojas E. Induction of p53 protein expression by sodium arsenite. Mutat. Res. 381 (1997) 259-265
-
(1997)
Mutat. Res.
, vol.381
, pp. 259-265
-
-
Salazar, A.M.1
Ostrosky-Wegman, P.2
Menendez, D.3
Miranda, E.4
Garcia-Carranca, A.5
Rojas, E.6
-
21
-
-
33745860070
-
SFTG international collaborative study on in vitro micronucleus test. III. Using CHO cells
-
Aardema M.J., Snyder R.D., Spicer C., Divi K., Morita T., Mauthe R.J., Gibson D.P., Soelter S., Curry P.T., Thybaud V., Lorenzon G., Marzin D., and Lorge E. SFTG international collaborative study on in vitro micronucleus test. III. Using CHO cells. Mutat. Res. 607 (2006) 61-87
-
(2006)
Mutat. Res.
, vol.607
, pp. 61-87
-
-
Aardema, M.J.1
Snyder, R.D.2
Spicer, C.3
Divi, K.4
Morita, T.5
Mauthe, R.J.6
Gibson, D.P.7
Soelter, S.8
Curry, P.T.9
Thybaud, V.10
Lorenzon, G.11
Marzin, D.12
Lorge, E.13
-
22
-
-
33745841361
-
SFTG international collaborative study on in vitro micronucleus test. V. Using L5178Y cells
-
Oliver J., Meunier J.R., Awogi T., Elhajouji A., Ouldelhkim M.C., Bichet N., Thybaud V., Lorenzon G., Marzin D., and Lorge E. SFTG international collaborative study on in vitro micronucleus test. V. Using L5178Y cells. Mutat. Res. 607 (2006) 125-152
-
(2006)
Mutat. Res.
, vol.607
, pp. 125-152
-
-
Oliver, J.1
Meunier, J.R.2
Awogi, T.3
Elhajouji, A.4
Ouldelhkim, M.C.5
Bichet, N.6
Thybaud, V.7
Lorenzon, G.8
Marzin, D.9
Lorge, E.10
-
23
-
-
33847325174
-
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: report of an ECVAM workshop
-
Kirkland D., Pfuhler S., Tweats D., Aardema M., Corvi R., Darroudi F., Elhajouji A., Glatt H., Hastwell P., Hayashi M., Kasper P., Kirchner S., Lynch A., Marzin D., Maurici D., Meunier J.R., Müller L., Nohynek G., Parry J., Parry E., Thybaud V., Tice R., van Benthem J., Vanparys P., and White P. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: report of an ECVAM workshop. Mutat. Res. 628 (2007) 31-55
-
(2007)
Mutat. Res.
, vol.628
, pp. 31-55
-
-
Kirkland, D.1
Pfuhler, S.2
Tweats, D.3
Aardema, M.4
Corvi, R.5
Darroudi, F.6
Elhajouji, A.7
Glatt, H.8
Hastwell, P.9
Hayashi, M.10
Kasper, P.11
Kirchner, S.12
Lynch, A.13
Marzin, D.14
Maurici, D.15
Meunier, J.R.16
Müller, L.17
Nohynek, G.18
Parry, J.19
Parry, E.20
Thybaud, V.21
Tice, R.22
van Benthem, J.23
Vanparys, P.24
White, P.25
more..
-
24
-
-
0034066102
-
Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils
-
Umegaki K., and Fenech M. Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis 15 (2000) 261-269
-
(2000)
Mutagenesis
, vol.15
, pp. 261-269
-
-
Umegaki, K.1
Fenech, M.2
-
25
-
-
53249153454
-
Flow-cytometric analysis of in vitro micronucleus formation: comparative studies with WIL2-NS human lymphoblastoid and L5178Y mouse lymphoma cell lines
-
Laingam S., Froscio S.M., and Humpage A.R. Flow-cytometric analysis of in vitro micronucleus formation: comparative studies with WIL2-NS human lymphoblastoid and L5178Y mouse lymphoma cell lines. Mutat. Res. 656 (2008) 19-26
-
(2008)
Mutat. Res.
, vol.656
, pp. 19-26
-
-
Laingam, S.1
Froscio, S.M.2
Humpage, A.R.3
-
26
-
-
0029911560
-
Automated scoring of micronuclei in binucleated human lymphocytes
-
Bocker W., Streffer C., Muller W.U., and Yu C. Automated scoring of micronuclei in binucleated human lymphocytes. Int. J. Radiat. Biol. 70 (1996) 529-537
-
(1996)
Int. J. Radiat. Biol.
, vol.70
, pp. 529-537
-
-
Bocker, W.1
Streffer, C.2
Muller, W.U.3
Yu, C.4
-
27
-
-
0030880339
-
Semi-automated micronucleus scoring in cytokinesis-blocked lymphocytes after irradiation
-
Thierens H., Vral A., De Scheerder F., De Ridder L., and Tates A. Semi-automated micronucleus scoring in cytokinesis-blocked lymphocytes after irradiation. Int. J. Radiat. Biol. 72 (1997) 319-324
-
(1997)
Int. J. Radiat. Biol.
, vol.72
, pp. 319-324
-
-
Thierens, H.1
Vral, A.2
De Scheerder, F.3
De Ridder, L.4
Tates, A.5
-
28
-
-
6444219993
-
An automated scoring procedure for the micronucleus test by image analysis
-
Varga D., Johannes T., Jainta S., Schuster S., Schwarz-Boeger U., Kiechle M., Patino Garcia B., and Vogel W. An automated scoring procedure for the micronucleus test by image analysis. Mutagenesis 19 (2004) 391-397
-
(2004)
Mutagenesis
, vol.19
, pp. 391-397
-
-
Varga, D.1
Johannes, T.2
Jainta, S.3
Schuster, S.4
Schwarz-Boeger, U.5
Kiechle, M.6
Patino Garcia, B.7
Vogel, W.8
-
30
-
-
33746309471
-
High-specificity and high-sensitivity genotoxicity assessment in a human cell line: validation of the GreenScreen HC GADD45a-GFP genotoxicity assay
-
Hastwell P.W., Chai L.L., Roberts K.J., Webster T.W., Harvey J.S., Rees R.W., and Walmsley R.M. High-specificity and high-sensitivity genotoxicity assessment in a human cell line: validation of the GreenScreen HC GADD45a-GFP genotoxicity assay. Mutat. Res. 607 (2006) 160-175
-
(2006)
Mutat. Res.
, vol.607
, pp. 160-175
-
-
Hastwell, P.W.1
Chai, L.L.2
Roberts, K.J.3
Webster, T.W.4
Harvey, J.S.5
Rees, R.W.6
Walmsley, R.M.7
-
31
-
-
49649106099
-
Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: an enabling study for independent validation as an alternative method
-
Billinton N., Hastwell P.W., Beerens D., Birrell L., Ellis P., Maskell S., Webster T.W., Windebank S., Woestenborghs F., Lynch A.M., Scott A.D., Tweats D.J., van Gompel J., Rees R.W., and Walmsley R.M. Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: an enabling study for independent validation as an alternative method. Mutat. Res. 653 (2008) 23-33
-
(2008)
Mutat. Res.
, vol.653
, pp. 23-33
-
-
Billinton, N.1
Hastwell, P.W.2
Beerens, D.3
Birrell, L.4
Ellis, P.5
Maskell, S.6
Webster, T.W.7
Windebank, S.8
Woestenborghs, F.9
Lynch, A.M.10
Scott, A.D.11
Tweats, D.J.12
van Gompel, J.13
Rees, R.W.14
Walmsley, R.M.15
-
32
-
-
0027470981
-
Induction of micronuclei in rat bone marrow and peripheral blood following acute and subchronic administration of azathioprine
-
Henderson L., Fedyk J., Windebank S., and Smith M. Induction of micronuclei in rat bone marrow and peripheral blood following acute and subchronic administration of azathioprine. Mutat. Res. 291 (1993) 79-85
-
(1993)
Mutat. Res.
, vol.291
, pp. 79-85
-
-
Henderson, L.1
Fedyk, J.2
Windebank, S.3
Smith, M.4
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