메뉴 건너뛰기




Volumn 4, Issue 1, 2013, Pages

The immune modifying effects of amino acids on gut-associated lymphoid tissue

Author keywords

Amino acids; Arginine; Epithelium; Glutamate; Glutamine; Gut associated lymphoid tissue; Intestine; Mucosa

Indexed keywords


EID: 84894546505     PISSN: 16749782     EISSN: 20491891     Source Type: Journal    
DOI: 10.1186/2049-1891-4-27     Document Type: Review
Times cited : (154)

References (93)
  • 1
    • 0036141210 scopus 로고    scopus 로고
    • Nutrients and their role in host resistance to infection
    • Field CJ, Johnson IR, Schley PD. Nutrients and their role in host resistance to infection. J Leukoc Biol 2002, 71:16-32.
    • (2002) J Leukoc Biol , vol.71 , pp. 16-32
    • Field, C.J.1    Johnson, I.R.2    Schley, P.D.3
  • 2
    • 0026285509 scopus 로고
    • Glutamine and glucose metabolism in thymocytes from normal and spontaneously diabetic BB rats
    • 10.1139/o91-120, 1818585
    • Wu GY, Field CJ, Marliss EB. Glutamine and glucose metabolism in thymocytes from normal and spontaneously diabetic BB rats. Biochem Cell Biol 1991, 69:801-808. 10.1139/o91-120, 1818585.
    • (1991) Biochem Cell Biol , vol.69 , pp. 801-808
    • Wu, G.Y.1    Field, C.J.2    Marliss, E.B.3
  • 3
    • 0025980192 scopus 로고
    • Elevated glutamine metabolism in splenocytes from spontaneously diabetic BB rats
    • 1149919, 1672065
    • Wu GY, Field CJ, Marliss EB. Elevated glutamine metabolism in splenocytes from spontaneously diabetic BB rats. Biochem J 1991, 274(Pt 1):49-54. 1149919, 1672065.
    • (1991) Biochem J , vol.274 , Issue.PART 1 , pp. 49-54
    • Wu, G.Y.1    Field, C.J.2    Marliss, E.B.3
  • 4
    • 0026068787 scopus 로고
    • Glutamine and glucose metabolism in rat splenocytes and mesenteric lymph node lymphocytes
    • Wu GY, Field CJ, Marliss EB. Glutamine and glucose metabolism in rat splenocytes and mesenteric lymph node lymphocytes. Am J Physiol 1991, 260:E141-E147.
    • (1991) Am J Physiol , vol.260
    • Wu, G.Y.1    Field, C.J.2    Marliss, E.B.3
  • 5
    • 0028110877 scopus 로고
    • Enhanced metabolism of glucose and glutamine in mesenteric lymph node lymphocytes from spontaneously diabetic BB rats
    • 10.1139/y94-117, 7828092
    • Field CJ, Wu G, Marliss EB. Enhanced metabolism of glucose and glutamine in mesenteric lymph node lymphocytes from spontaneously diabetic BB rats. Can J Physiol Pharmacol 1994, 72:827-832. 10.1139/y94-117, 7828092.
    • (1994) Can J Physiol Pharmacol , vol.72 , pp. 827-832
    • Field, C.J.1    Wu, G.2    Marliss, E.B.3
  • 6
    • 80053112410 scopus 로고    scopus 로고
    • New role of glutamate as an immunoregulator via glutamate receptors and transporters
    • Xue H, Field CJ. New role of glutamate as an immunoregulator via glutamate receptors and transporters. Front Biosci (Schol Ed) 2011, 3:1007-1020.
    • (2011) Front Biosci (Schol Ed) , vol.3 , pp. 1007-1020
    • Xue, H.1    Field, C.J.2
  • 7
    • 84882653868 scopus 로고    scopus 로고
    • Functional amino acids in nutrition and health
    • [Epub ahead of print]
    • Wu G. Functional amino acids in nutrition and health. Amino Acids 2013, [Epub ahead of print].
    • (2013) Amino Acids
    • Wu, G.1
  • 8
    • 0042866144 scopus 로고    scopus 로고
    • Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function
    • 10.1146/annurev.nutr.23.011702.073036, 12626687
    • Ziegler TR, Evans ME, Fernandez-Estivariz C, Jones DP. Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function. Annu Rev Nutr 2003, 23:229-261. 10.1146/annurev.nutr.23.011702.073036, 12626687.
    • (2003) Annu Rev Nutr , vol.23 , pp. 229-261
    • Ziegler, T.R.1    Evans, M.E.2    Fernandez-Estivariz, C.3    Jones, D.P.4
  • 9
    • 38649137730 scopus 로고    scopus 로고
    • 4. Gastrointestinal mucosal immunity
    • 10.1016/j.jaci.2007.10.023, 18241686
    • Wershil BK, Furuta GT. 4. Gastrointestinal mucosal immunity. J Allergy Clin Immunol 2008, 121:S380-S383. 10.1016/j.jaci.2007.10.023, 18241686.
    • (2008) J Allergy Clin Immunol , vol.121
    • Wershil, B.K.1    Furuta, G.T.2
  • 10
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • 10.1038/nri2653, 19855405
    • Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009, 9:799-809. 10.1038/nri2653, 19855405.
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 11
    • 44349132270 scopus 로고    scopus 로고
    • Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
    • 10.1038/nri2316, 18469830
    • Artis D. Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 2008, 8:411-420. 10.1038/nri2316, 18469830.
    • (2008) Nat Rev Immunol , vol.8 , pp. 411-420
    • Artis, D.1
  • 12
    • 33846798312 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine
    • 10.1111/j.1600-065X.2006.00475.x, 17291285
    • Kunisawa J, Takahashi I, Kiyono H. Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine. Immunol Rev 2007, 215:136-153. 10.1111/j.1600-065X.2006.00475.x, 17291285.
    • (2007) Immunol Rev , vol.215 , pp. 136-153
    • Kunisawa, J.1    Takahashi, I.2    Kiyono, H.3
  • 13
    • 0343607261 scopus 로고    scopus 로고
    • Mucosa-Associated Lymphoid Tissue (MALT)
    • United Kingdom: Elsevier Ltd, Academic Press Inc., Roitt I, Delves P, 2
    • McGhee J. Mucosa-Associated Lymphoid Tissue (MALT). Encyclopedia of Immunology 1998, 1774-1780. United Kingdom: Elsevier Ltd, Academic Press Inc., Roitt I, Delves P, 2.
    • (1998) Encyclopedia of Immunology , pp. 1774-1780
    • McGhee, J.1
  • 14
    • 0029939741 scopus 로고    scopus 로고
    • Identification of gamma delta T lymphocyte subsets that populate calf ileal mucosa after birth
    • 10.1016/0165-2427(95)05535-5, 8807779
    • Wyatt CR, Brackett EJ, Perryman LE, Davis WC. Identification of gamma delta T lymphocyte subsets that populate calf ileal mucosa after birth. Vet Immunol Immunopathol 1996, 52:91-103. 10.1016/0165-2427(95)05535-5, 8807779.
    • (1996) Vet Immunol Immunopathol , vol.52 , pp. 91-103
    • Wyatt, C.R.1    Brackett, E.J.2    Perryman, L.E.3    Davis, W.C.4
  • 15
    • 0034653763 scopus 로고    scopus 로고
    • Predominant subpopulations of T lymphocytes in the mammary gland secretions during lactation and intraepithelial T lymphocytes in the intestine of dairy cows
    • 10.1016/S0165-2427(00)00158-6, 10713337
    • Asai K, Komine Y, Kozutsumi T, Yamaguchi T, Komine K, Kumagai K. Predominant subpopulations of T lymphocytes in the mammary gland secretions during lactation and intraepithelial T lymphocytes in the intestine of dairy cows. Vet Immunol Immunopathol 2000, 73:233-240. 10.1016/S0165-2427(00)00158-6, 10713337.
    • (2000) Vet Immunol Immunopathol , vol.73 , pp. 233-240
    • Asai, K.1    Komine, Y.2    Kozutsumi, T.3    Yamaguchi, T.4    Komine, K.5    Kumagai, K.6
  • 16
    • 0036284365 scopus 로고    scopus 로고
    • Getting to the guts of immune regulation
    • 10.1046/j.1365-2567.2002.01445.x, 1782714, 12047743
    • Bilsborough J, Viney JL. Getting to the guts of immune regulation. Immunology 2002, 106:139-143. 10.1046/j.1365-2567.2002.01445.x, 1782714, 12047743.
    • (2002) Immunology , vol.106 , pp. 139-143
    • Bilsborough, J.1    Viney, J.L.2
  • 17
    • 23344445169 scopus 로고    scopus 로고
    • Organizing a mucosal defense
    • 10.1111/j.0105-2896.2005.00282.x, 16048539
    • Newberry RD, Lorenz RG. Organizing a mucosal defense. Immunol Rev 2005, 206:6-21. 10.1111/j.0105-2896.2005.00282.x, 16048539.
    • (2005) Immunol Rev , vol.206 , pp. 6-21
    • Newberry, R.D.1    Lorenz, R.G.2
  • 18
    • 0035711607 scopus 로고    scopus 로고
    • Dendritic cells shuttle microbes across gut epithelial monolayers
    • 10.1078/0171-2985-00094, 11846220
    • Rescigno M, Rotta G, Valzasina B, Ricciardi-Castagnoli P. Dendritic cells shuttle microbes across gut epithelial monolayers. Immunobiology 2001, 204:572-581. 10.1078/0171-2985-00094, 11846220.
    • (2001) Immunobiology , vol.204 , pp. 572-581
    • Rescigno, M.1    Rotta, G.2    Valzasina, B.3    Ricciardi-Castagnoli, P.4
  • 19
    • 80054982785 scopus 로고    scopus 로고
    • The gut as communicator between environment and host: immunological consequences
    • Brandtzaeg P. The gut as communicator between environment and host: immunological consequences. Eur J Pharmacol 2011, 668(Suppl 1):S16-S32.
    • (2011) Eur J Pharmacol , vol.668 , Issue.SUPPL. 1
    • Brandtzaeg, P.1
  • 20
    • 58149480221 scopus 로고    scopus 로고
    • Effects of feeding fish oil on mesenteric lymph node cytokine responses in obese leptin receptor-deficient JCR:LA-cp rats
    • Ruth MR, Proctor SD, Field CJ. Effects of feeding fish oil on mesenteric lymph node cytokine responses in obese leptin receptor-deficient JCR:LA-cp rats. Int J Obes (Lond) 2009, 33:96-103.
    • (2009) Int J Obes (Lond) , vol.33 , pp. 96-103
    • Ruth, M.R.1    Proctor, S.D.2    Field, C.J.3
  • 21
    • 0029876258 scopus 로고    scopus 로고
    • Distribution of porcine CD4/CD8 double-positive T lymphocytes in mucosa-associated lymphoid tissues
    • 10.1046/j.1365-2567.1996.494570.x, 1384122, 8778039
    • Zuckermann FA, Gaskins HR. Distribution of porcine CD4/CD8 double-positive T lymphocytes in mucosa-associated lymphoid tissues. Immunology 1996, 87:493-499. 10.1046/j.1365-2567.1996.494570.x, 1384122, 8778039.
    • (1996) Immunology , vol.87 , pp. 493-499
    • Zuckermann, F.A.1    Gaskins, H.R.2
  • 22
    • 33746296511 scopus 로고    scopus 로고
    • Glutamine supplementation influences immune development in the newly weaned piglet
    • 10.1016/j.dci.2006.03.003, 16697041
    • Johnson IR, Ball RO, Baracos VE, Field CJ. Glutamine supplementation influences immune development in the newly weaned piglet. Dev Comp Immunol 2006, 30:1191-1202. 10.1016/j.dci.2006.03.003, 16697041.
    • (2006) Dev Comp Immunol , vol.30 , pp. 1191-1202
    • Johnson, I.R.1    Ball, R.O.2    Baracos, V.E.3    Field, C.J.4
  • 23
    • 70450064812 scopus 로고    scopus 로고
    • Mucosal immunity: induction, dissemination, and effector functions
    • 10.1111/j.1365-3083.2009.02319.x, 19906191
    • Brandtzaeg P. Mucosal immunity: induction, dissemination, and effector functions. Scand J Immunol 2009, 70:505-515. 10.1111/j.1365-3083.2009.02319.x, 19906191.
    • (2009) Scand J Immunol , vol.70 , pp. 505-515
    • Brandtzaeg, P.1
  • 24
    • 0026579998 scopus 로고
    • The mucosal immune system: from fundamental concepts to vaccine development
    • 10.1016/0264-410X(92)90021-B, 1539467
    • McGhee JR, Mestecky J, Dertzbaugh MT, Eldridge JH, Hirasawa M, Kiyono H. The mucosal immune system: from fundamental concepts to vaccine development. Vaccine 1992, 10:75-88. 10.1016/0264-410X(92)90021-B, 1539467.
    • (1992) Vaccine , vol.10 , pp. 75-88
    • McGhee, J.R.1    Mestecky, J.2    Dertzbaugh, M.T.3    Eldridge, J.H.4    Hirasawa, M.5    Kiyono, H.6
  • 25
    • 77952149753 scopus 로고    scopus 로고
    • Secretory IgA: arresting microbial pathogens at epithelial borders
    • 10.3109/08820131003622635, 20450284
    • Mantis NJ, Forbes SJ. Secretory IgA: arresting microbial pathogens at epithelial borders. Immunol Invest 2010, 39:383-406. 10.3109/08820131003622635, 20450284.
    • (2010) Immunol Invest , vol.39 , pp. 383-406
    • Mantis, N.J.1    Forbes, S.J.2
  • 26
    • 70449713437 scopus 로고    scopus 로고
    • Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes
    • 10.1016/j.jaci.2009.06.018, 19665769
    • Agarwal S, Mayer L. Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes. J Allergy Clin Immunol 2009, 124:658-664. 10.1016/j.jaci.2009.06.018, 19665769.
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 658-664
    • Agarwal, S.1    Mayer, L.2
  • 27
    • 36749058847 scopus 로고    scopus 로고
    • Evidence that amino-acid residues are responsible for substrate synergism of locust arginine kinase
    • 10.1016/j.ibmb.2007.09.004, 18070665
    • Wu QY, Li F, Wang XY. Evidence that amino-acid residues are responsible for substrate synergism of locust arginine kinase. Insect Biochem Mol Biol 2008, 38:59-65. 10.1016/j.ibmb.2007.09.004, 18070665.
    • (2008) Insect Biochem Mol Biol , vol.38 , pp. 59-65
    • Wu, Q.Y.1    Li, F.2    Wang, X.Y.3
  • 28
    • 0029842804 scopus 로고    scopus 로고
    • Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs
    • Wu G, Meier SA, Knabe DA. Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. J Nutr 1996, 126:2578-2584.
    • (1996) J Nutr , vol.126 , pp. 2578-2584
    • Wu, G.1    Meier, S.A.2    Knabe, D.A.3
  • 29
    • 63649111659 scopus 로고    scopus 로고
    • Amino acids: metabolism, functions, and nutrition
    • Wu G. Amino acids: metabolism, functions, and nutrition. Amino Acids 2009, 37:1-17.
    • (2009) Amino Acids , vol.37 , pp. 1-17
    • Wu, G.1
  • 30
    • 0028959420 scopus 로고
    • Glutamine and glucose metabolism in enterocytes of the neonatal pig
    • Wu G, Knabe DA, Yan W, Flynn NE. Glutamine and glucose metabolism in enterocytes of the neonatal pig. Am J Physiol 1995, 268:R334-R342.
    • (1995) Am J Physiol , vol.268
    • Wu, G.1    Knabe, D.A.2    Yan, W.3    Flynn, N.E.4
  • 31
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Glutathione metabolism and its implications for health. J Nutr 2004, 134:489-492.
    • (2004) J Nutr , vol.134 , pp. 489-492
    • Wu, G.1    Fang, Y.Z.2    Yang, S.3    Lupton, J.R.4    Turner, N.D.5
  • 32
    • 0033489873 scopus 로고    scopus 로고
    • Glutamine and the immune system
    • 10.1007/BF01366922, 10582122
    • Calder PC, Yaqoob P. Glutamine and the immune system. Amino Acids 1999, 17:227-241. 10.1007/BF01366922, 10582122.
    • (1999) Amino Acids , vol.17 , pp. 227-241
    • Calder, P.C.1    Yaqoob, P.2
  • 33
    • 31544463778 scopus 로고    scopus 로고
    • Can nutraceuticals affect the structure of intestinal mucosa? Qualitative and quantitative microanatomy in L-glutamine diet-supplemented weaning piglets
    • 10.1007/s11259-006-3236-1, 16437309
    • Domeneghini C, Di GA, Bosi G, Arrighi S. Can nutraceuticals affect the structure of intestinal mucosa? Qualitative and quantitative microanatomy in L-glutamine diet-supplemented weaning piglets. Vet Res Commun 2006, 30:331-342. 10.1007/s11259-006-3236-1, 16437309.
    • (2006) Vet Res Commun , vol.30 , pp. 331-342
    • Domeneghini, C.1    Di, G.A.2    Bosi, G.3    Arrighi, S.4
  • 34
    • 44449177607 scopus 로고    scopus 로고
    • Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation
    • Wang J, Chen L, Li P, Li X, Zhou H, Wang F, et al. Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation. J Nutr 2008, 138:1025-1032.
    • (2008) J Nutr , vol.138 , pp. 1025-1032
    • Wang, J.1    Chen, L.2    Li, P.3    Li, X.4    Zhou, H.5    Wang, F.6
  • 35
    • 0024330650 scopus 로고
    • Maintenance of small bowel mucosa with glutamine-enriched parenteral nutrition
    • 10.1177/0148607189013006579, 2515303
    • O'Dwyer ST, Smith RJ, Hwang TL, Wilmore DW. Maintenance of small bowel mucosa with glutamine-enriched parenteral nutrition. JPEN J Parenter Enteral Nutr 1989, 13:579-585. 10.1177/0148607189013006579, 2515303.
    • (1989) JPEN J Parenter Enteral Nutr , vol.13 , pp. 579-585
    • O'Dwyer, S.T.1    Smith, R.J.2    Hwang, T.L.3    Wilmore, D.W.4
  • 36
    • 0028232336 scopus 로고
    • Glutamine prevents parenteral nutrition-induced increases in intestinal permeability
    • 10.1177/0148607194018004303, 7933435
    • Li J, Langkamp-Henken B, Suzuki K, Stahlgren LH. Glutamine prevents parenteral nutrition-induced increases in intestinal permeability. JPEN J Parenter Enteral Nutr 1994, 18:303-307. 10.1177/0148607194018004303, 7933435.
    • (1994) JPEN J Parenter Enteral Nutr , vol.18 , pp. 303-307
    • Li, J.1    Langkamp-Henken, B.2    Suzuki, K.3    Stahlgren, L.H.4
  • 37
    • 77649302757 scopus 로고    scopus 로고
    • Glutamine prevents total parenteral nutrition-associated changes to intraepithelial lymphocyte phenotype and function: a potential mechanism for the preservation of epithelial barrier function
    • 10.1089/jir.2009.0046, 2830305,2830305, 20028208
    • Nose K, Yang H, Sun X, Nose S, Koga H, Feng Y, et al. Glutamine prevents total parenteral nutrition-associated changes to intraepithelial lymphocyte phenotype and function: a potential mechanism for the preservation of epithelial barrier function. J Interferon Cytokine Res 2010, 30:67-80. 10.1089/jir.2009.0046, 2830305,2830305, 20028208.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 67-80
    • Nose, K.1    Yang, H.2    Sun, X.3    Nose, S.4    Koga, H.5    Feng, Y.6
  • 38
    • 80555156803 scopus 로고    scopus 로고
    • Glutamine supplementation improves intestinal barrier function in a weaned piglet model of Escherichia coli infection
    • 10.1017/S0007114511001152, 21736826
    • Ewaschuk JB, Murdoch GK, Johnson IR, Madsen KL, Field CJ. Glutamine supplementation improves intestinal barrier function in a weaned piglet model of Escherichia coli infection. Br J Nutr 2011, 106:870-877. 10.1017/S0007114511001152, 21736826.
    • (2011) Br J Nutr , vol.106 , pp. 870-877
    • Ewaschuk, J.B.1    Murdoch, G.K.2    Johnson, I.R.3    Madsen, K.L.4    Field, C.J.5
  • 39
    • 33644654746 scopus 로고    scopus 로고
    • Effect of glutamine and spray-dried plasma on growth performance, small intestinal morphology, and immune responses of Escherichia coli K88 + -challenged weaned pigs
    • Yi GF, Carroll JA, Allee GL, Gaines AM, Kendall DC, Usry JL, et al. Effect of glutamine and spray-dried plasma on growth performance, small intestinal morphology, and immune responses of Escherichia coli K88 + -challenged weaned pigs. J Anim Sci 2005, 83:634-643.
    • (2005) J Anim Sci , vol.83 , pp. 634-643
    • Yi, G.F.1    Carroll, J.A.2    Allee, G.L.3    Gaines, A.M.4    Kendall, D.C.5    Usry, J.L.6
  • 40
    • 67349130218 scopus 로고    scopus 로고
    • L-Glutamine or L-alanyl-L-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes
    • 10.1007/s00726-009-0243-x, 19189199
    • Haynes TE, Li P, Li X, Shimotori K, Sato H, Flynn NE, et al. L-Glutamine or L-alanyl-L-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes. Amino Acids 2009, 37:131-142. 10.1007/s00726-009-0243-x, 19189199.
    • (2009) Amino Acids , vol.37 , pp. 131-142
    • Haynes, T.E.1    Li, P.2    Li, X.3    Shimotori, K.4    Sato, H.5    Flynn, N.E.6
  • 41
    • 34548056132 scopus 로고    scopus 로고
    • Dietary glutamine affects mucosal functions in rats with mild DSS-induced colitis
    • Vicario M, Amat C, Rivero M, Moreto M, Pelegri C. Dietary glutamine affects mucosal functions in rats with mild DSS-induced colitis. J Nutr 2007, 137:1931-1937.
    • (2007) J Nutr , vol.137 , pp. 1931-1937
    • Vicario, M.1    Amat, C.2    Rivero, M.3    Moreto, M.4    Pelegri, C.5
  • 42
    • 0034843181 scopus 로고    scopus 로고
    • Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?
    • Newsholme P. Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?. J Nutr 2001, 131:2515S-2522S.
    • (2001) J Nutr , vol.131
    • Newsholme, P.1
  • 43
    • 84866325338 scopus 로고    scopus 로고
    • Effects of glutamine supplementation on the immune status in weaning piglets with intrauterine growth retardation
    • 10.1080/1745039X.2012.683325, 22962945
    • Zhong X, Li W, Huang X, Wang Y, Zhang L, Zhou Y, et al. Effects of glutamine supplementation on the immune status in weaning piglets with intrauterine growth retardation. Arch Anim Nutr 2012, 66:347-356. 10.1080/1745039X.2012.683325, 22962945.
    • (2012) Arch Anim Nutr , vol.66 , pp. 347-356
    • Zhong, X.1    Li, W.2    Huang, X.3    Wang, Y.4    Zhang, L.5    Zhou, Y.6
  • 44
    • 0026502292 scopus 로고
    • The effect of glutamine-enriched TPN on gut immune cellularity
    • 10.1016/0022-4804(92)90275-5, 1548865
    • Alverdy JA, Aoys E, Weiss-Carrington P, Burke DA. The effect of glutamine-enriched TPN on gut immune cellularity. J Surg Res 1992, 52:34-38. 10.1016/0022-4804(92)90275-5, 1548865.
    • (1992) J Surg Res , vol.52 , pp. 34-38
    • Alverdy, J.A.1    Aoys, E.2    Weiss-Carrington, P.3    Burke, D.A.4
  • 45
    • 1342329222 scopus 로고    scopus 로고
    • Glutamine supplementation enhances mucosal immunity in rats with Gut-Derived sepsis
    • 10.1016/j.nut.2003.11.015, 14990270
    • Lai YN, Yeh SL, Lin MT, Shang HF, Yeh CL, Chen WJ. Glutamine supplementation enhances mucosal immunity in rats with Gut-Derived sepsis. Nutrition 2004, 20:286-291. 10.1016/j.nut.2003.11.015, 14990270.
    • (2004) Nutrition , vol.20 , pp. 286-291
    • Lai, Y.N.1    Yeh, S.L.2    Lin, M.T.3    Shang, H.F.4    Yeh, C.L.5    Chen, W.J.6
  • 46
    • 0034941504 scopus 로고    scopus 로고
    • Oral feeding with glutamine prevents lymphocyte and glutathione depletion of Peyer's patches in endotoxemic mice
    • 10.1097/00000658-200107000-00014, 1421953, 11420488
    • Manhart N, Vierlinger K, Spittler A, Bergmeister H, Sautner T, Roth E. Oral feeding with glutamine prevents lymphocyte and glutathione depletion of Peyer's patches in endotoxemic mice. Ann Surg 2001, 234:92-97. 10.1097/00000658-200107000-00014, 1421953, 11420488.
    • (2001) Ann Surg , vol.234 , pp. 92-97
    • Manhart, N.1    Vierlinger, K.2    Spittler, A.3    Bergmeister, H.4    Sautner, T.5    Roth, E.6
  • 47
    • 84865524413 scopus 로고    scopus 로고
    • Glutamine modulates sepsis-induced changes to intestinal intraepithelial gammadeltaT lymphocyte expression in mice
    • 10.1097/SHK.0b013e3182655932, 22777117
    • Lee WY, Hu YM, Ko TL, Yeh SL, Yeh CL. Glutamine modulates sepsis-induced changes to intestinal intraepithelial gammadeltaT lymphocyte expression in mice. Shock 2012, 38:288-293. 10.1097/SHK.0b013e3182655932, 22777117.
    • (2012) Shock , vol.38 , pp. 288-293
    • Lee, W.Y.1    Hu, Y.M.2    Ko, T.L.3    Yeh, S.L.4    Yeh, C.L.5
  • 48
    • 84877631757 scopus 로고    scopus 로고
    • Glutamine modulates CD8alphaalpha TCRalphabeta intestinal intraepithelial lymphocyte expression in mice with polymicrobial sepsis
    • 10.1016/j.nut.2013.01.001, 23522839
    • Tung JN, Lee WY, Pai MH, Chen WJ, Yeh CL, Yeh SL. Glutamine modulates CD8alphaalpha TCRalphabeta intestinal intraepithelial lymphocyte expression in mice with polymicrobial sepsis. Nutrition 2013, 29:911-917. 10.1016/j.nut.2013.01.001, 23522839.
    • (2013) Nutrition , vol.29 , pp. 911-917
    • Tung, J.N.1    Lee, W.Y.2    Pai, M.H.3    Chen, W.J.4    Yeh, C.L.5    Yeh, S.L.6
  • 49
    • 59449102327 scopus 로고    scopus 로고
    • Dietary glutamine and oral antibiotics each improve indexes of gut barrier function in rat short bowel syndrome
    • 2643904,2643904, 19095767
    • Tian J, Hao L, Chandra P, Jones DP, Willams IR, Gewirtz AT, et al. Dietary glutamine and oral antibiotics each improve indexes of gut barrier function in rat short bowel syndrome. Am J Physiol Gastrointest Liver Physiol 2009, 296:G348-G355. 2643904,2643904, 19095767.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Tian, J.1    Hao, L.2    Chandra, P.3    Jones, D.P.4    Willams, I.R.5    Gewirtz, A.T.6
  • 50
    • 0031007679 scopus 로고    scopus 로고
    • Effect of glutamine-enriched total parenteral nutrition on small intestinal gut-associated lymphoid tissue and upper respiratory tract immunity
    • 10.1016/S0039-6060(97)90109-4, 9142153
    • Li J, Kudsk KA, Janu P, Renegar KB. Effect of glutamine-enriched total parenteral nutrition on small intestinal gut-associated lymphoid tissue and upper respiratory tract immunity. Surgery 1997, 121:542-549. 10.1016/S0039-6060(97)90109-4, 9142153.
    • (1997) Surgery , vol.121 , pp. 542-549
    • Li, J.1    Kudsk, K.A.2    Janu, P.3    Renegar, K.B.4
  • 51
    • 0033659162 scopus 로고    scopus 로고
    • Glutamine-enriched total parenteral nutrition maintains intestinal interleukin-4 and mucosal immunoglobulin A levels
    • 10.1177/0148607100024005270, 11011781
    • Kudsk KA, Wu Y, Fukatsu K, Zarzaur BL, Johnson CD, Wang R, et al. Glutamine-enriched total parenteral nutrition maintains intestinal interleukin-4 and mucosal immunoglobulin A levels. JPEN J Parenter Enteral Nutr 2000, 24:270-274. 10.1177/0148607100024005270, 11011781.
    • (2000) JPEN J Parenter Enteral Nutr , vol.24 , pp. 270-274
    • Kudsk, K.A.1    Wu, Y.2    Fukatsu, K.3    Zarzaur, B.L.4    Johnson, C.D.5    Wang, R.6
  • 52
    • 70349578566 scopus 로고    scopus 로고
    • Metabolism and functions of L-glutamate in the epithelial cells of the small and large intestines
    • 10.3945/ajcn.2009.27462S, 19571215
    • Blachier F, Boutry C, Bos C, Tome D. Metabolism and functions of L-glutamate in the epithelial cells of the small and large intestines. Am J Clin Nutr 2009, 90:814S-821S. 10.3945/ajcn.2009.27462S, 19571215.
    • (2009) Am J Clin Nutr , vol.90
    • Blachier, F.1    Boutry, C.2    Bos, C.3    Tome, D.4
  • 53
    • 0030832183 scopus 로고    scopus 로고
    • Enteral glutamate is the preferential source for mucosal glutathione synthesis in fed piglets
    • Reeds PJ, Burrin DG, Stoll B, Jahoor F, Wykes L, Henry J, et al. Enteral glutamate is the preferential source for mucosal glutathione synthesis in fed piglets. Am J Physiol 1997, 273:E408-E415.
    • (1997) Am J Physiol , vol.273
    • Reeds, P.J.1    Burrin, D.G.2    Stoll, B.3    Jahoor, F.4    Wykes, L.5    Henry, J.6
  • 54
    • 33845370329 scopus 로고    scopus 로고
    • Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs
    • Berger UV, Hediger MA. Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs. Anat Embryol (Berl) 2006, 211:595-606.
    • (2006) Anat Embryol (Berl) , vol.211 , pp. 595-606
    • Berger, U.V.1    Hediger, M.A.2
  • 55
    • 0033920138 scopus 로고    scopus 로고
    • Dispensable and indispensable amino acids for humans
    • Reeds PJ. Dispensable and indispensable amino acids for humans. J Nutr 2000, 130:1835S-1840S.
    • (2000) J Nutr , vol.130
    • Reeds, P.J.1
  • 56
    • 79955934646 scopus 로고    scopus 로고
    • Glutamate reduces experimental intestinal hyperpermeability and facilitates glutamine support of gut integrity
    • 10.3748/wjg.v17.i12.1569, 3070128, 21472123
    • Vermeulen MA, De Jong J, Vaessen MJ, van Leeuwen PA, Houdijk AP. Glutamate reduces experimental intestinal hyperpermeability and facilitates glutamine support of gut integrity. World J Gastroenterol 2011, 17:1569-1573. 10.3748/wjg.v17.i12.1569, 3070128, 21472123.
    • (2011) World J Gastroenterol , vol.17 , pp. 1569-1573
    • Vermeulen, M.A.1    De Jong, J.2    Vaessen, M.J.3    van Leeuwen, P.A.4    Houdijk, A.P.5
  • 57
    • 84882568427 scopus 로고    scopus 로고
    • Effects of oral supplementation with glutamate or combination of glutamate and N-carbamylglutamate on intestinal mucosa morphology and epithelium cell proliferation in weanling piglets
    • Wu X, Zhang Y, Liu Z, Li TJ, Yin YL. Effects of oral supplementation with glutamate or combination of glutamate and N-carbamylglutamate on intestinal mucosa morphology and epithelium cell proliferation in weanling piglets. J Anim Sci 2012, 90(Suppl 4):337-339.
    • (2012) J Anim Sci , vol.90 , Issue.SUPPL. 4 , pp. 337-339
    • Wu, X.1    Zhang, Y.2    Liu, Z.3    Li, T.J.4    Yin, Y.L.5
  • 58
    • 33748073766 scopus 로고    scopus 로고
    • Effects of glutamic acid and taurine on total parenteral nutrition
    • 10.1016/j.jpedsurg.2006.05.021, 16952593
    • Tsuchioka T, Fujiwara T, Sunagawa M. Effects of glutamic acid and taurine on total parenteral nutrition. J Pediatr Surg 2006, 41:1566-1572. 10.1016/j.jpedsurg.2006.05.021, 16952593.
    • (2006) J Pediatr Surg , vol.41 , pp. 1566-1572
    • Tsuchioka, T.1    Fujiwara, T.2    Sunagawa, M.3
  • 59
    • 0037223543 scopus 로고    scopus 로고
    • Cyclosporine-A treatment inhibits the expression of metabotropic glutamate receptors in rat thymus
    • 10.1078/0065-1281-00688, 12666991
    • Rezzani R, Corsetti G, Rodella L, Angoscini P, Lonati C, Bianchi R. Cyclosporine-A treatment inhibits the expression of metabotropic glutamate receptors in rat thymus. Acta Histochem 2003, 105:81-87. 10.1078/0065-1281-00688, 12666991.
    • (2003) Acta Histochem , vol.105 , pp. 81-87
    • Rezzani, R.1    Corsetti, G.2    Rodella, L.3    Angoscini, P.4    Lonati, C.5    Bianchi, R.6
  • 60
    • 79953301329 scopus 로고    scopus 로고
    • Glutamate signaling through the kainate receptor enhances human immunoglobulin production
    • 10.1016/j.jneuroim.2010.11.014, 3074000, 21215464
    • Sturgill JL, Mathews J, Scherle P, Conrad DH. Glutamate signaling through the kainate receptor enhances human immunoglobulin production. J Neuroimmunol 2011, 233:80-89. 10.1016/j.jneuroim.2010.11.014, 3074000, 21215464.
    • (2011) J Neuroimmunol , vol.233 , pp. 80-89
    • Sturgill, J.L.1    Mathews, J.2    Scherle, P.3    Conrad, D.H.4
  • 62
    • 84871914342 scopus 로고    scopus 로고
    • Nitrogen in dietary glutamate is utilized exclusively for the synthesis of amino acids in the rat intestine
    • 10.1152/ajpendo.00331.2012, 23115079
    • Nakamura H, Kawamata Y, Kuwahara T, Torii K, Sakai R. Nitrogen in dietary glutamate is utilized exclusively for the synthesis of amino acids in the rat intestine. Am J Physiol Endocrinol Metab 2013, 304:E100-E108. 10.1152/ajpendo.00331.2012, 23115079.
    • (2013) Am J Physiol Endocrinol Metab , vol.304
    • Nakamura, H.1    Kawamata, Y.2    Kuwahara, T.3    Torii, K.4    Sakai, R.5
  • 63
    • 34249827735 scopus 로고    scopus 로고
    • Amino acids and immune function
    • 10.1017/S000711450769936X, 17403271
    • Li P, Yin YL, Li D, Kim SW, Wu G. Amino acids and immune function. Br J Nutr 2007, 98:237-252. 10.1017/S000711450769936X, 17403271.
    • (2007) Br J Nutr , vol.98 , pp. 237-252
    • Li, P.1    Yin, Y.L.2    Li, D.3    Kim, S.W.4    Wu, G.5
  • 65
    • 77956903989 scopus 로고    scopus 로고
    • Dietary supplementation with L-arginine or N-carbamylglutamate enhances intestinal growth and heat shock protein-70 expression in weanling pigs fed a corn- and soybean meal-based diet
    • 10.1007/s00726-010-0538-y, 20213438
    • Wu X, Ruan Z, Gao Y, Yin Y, Zhou X, Wang L, et al. Dietary supplementation with L-arginine or N-carbamylglutamate enhances intestinal growth and heat shock protein-70 expression in weanling pigs fed a corn- and soybean meal-based diet. Amino Acids 2010, 39:831-839. 10.1007/s00726-010-0538-y, 20213438.
    • (2010) Amino Acids , vol.39 , pp. 831-839
    • Wu, X.1    Ruan, Z.2    Gao, Y.3    Yin, Y.4    Zhou, X.5    Wang, L.6
  • 66
    • 67650766426 scopus 로고    scopus 로고
    • Dietary L-arginine supplementation enhances the immune status in early-weaned piglets
    • 10.1007/s00726-008-0155-1, 18712273
    • Tan B, Li XG, Kong X, Huang R, Ruan Z, Yao K, et al. Dietary L-arginine supplementation enhances the immune status in early-weaned piglets. Amino Acids 2009, 37:323-331. 10.1007/s00726-008-0155-1, 18712273.
    • (2009) Amino Acids , vol.37 , pp. 323-331
    • Tan, B.1    Li, X.G.2    Kong, X.3    Huang, R.4    Ruan, Z.5    Yao, K.6
  • 67
    • 33947149127 scopus 로고    scopus 로고
    • Dietary L-arginine supplementation enhances the reproductive performance of gilts
    • Mateo RD, Wu G, Bazer FW, Park JC, Shinzato I, Kim SW. Dietary L-arginine supplementation enhances the reproductive performance of gilts. J Nutr 2007, 137:652-656.
    • (2007) J Nutr , vol.137 , pp. 652-656
    • Mateo, R.D.1    Wu, G.2    Bazer, F.W.3    Park, J.C.4    Shinzato, I.5    Kim, S.W.6
  • 68
    • 1542286855 scopus 로고    scopus 로고
    • Dietary arginine supplementation enhances the growth of milk-fed young pigs
    • Kim SW, Wu G. Dietary arginine supplementation enhances the growth of milk-fed young pigs. J Nutr 2004, 134:625-630.
    • (2004) J Nutr , vol.134 , pp. 625-630
    • Kim, S.W.1    Wu, G.2
  • 69
    • 79953145324 scopus 로고    scopus 로고
    • Dietary L-arginine supplementation enhances intestinal development and expression of vascular endothelial growth factor in weanling piglets
    • 10.1017/S000711451000365X, 21219670
    • Yao K, Guan S, Li T, Huang R, Wu G, Ruan Z, et al. Dietary L-arginine supplementation enhances intestinal development and expression of vascular endothelial growth factor in weanling piglets. Br J Nutr 2011, 105:703-709. 10.1017/S000711451000365X, 21219670.
    • (2011) Br J Nutr , vol.105 , pp. 703-709
    • Yao, K.1    Guan, S.2    Li, T.3    Huang, R.4    Wu, G.5    Ruan, Z.6
  • 70
    • 46249126792 scopus 로고    scopus 로고
    • Dietary arginine supplementation affects microvascular development in the small intestine of early-weaned pigs
    • Zhan Z, Ou D, Piao X, Kim SW, Liu Y, Wang J. Dietary arginine supplementation affects microvascular development in the small intestine of early-weaned pigs. J Nutr 2008, 138:1304-1309.
    • (2008) J Nutr , vol.138 , pp. 1304-1309
    • Zhan, Z.1    Ou, D.2    Piao, X.3    Kim, S.W.4    Liu, Y.5    Wang, J.6
  • 71
    • 8844248001 scopus 로고    scopus 로고
    • Oral arginine reduces gut mucosal injury caused by lipopolysaccharide endotoxemia in rat
    • 10.1016/j.jss.2004.07.004, 15555626
    • Sukhotnik I, Mogilner J, Krausz MM, Lurie M, Hirsh M, Coran AG, et al. Oral arginine reduces gut mucosal injury caused by lipopolysaccharide endotoxemia in rat. J Surg Res 2004, 122:256-262. 10.1016/j.jss.2004.07.004, 15555626.
    • (2004) J Surg Res , vol.122 , pp. 256-262
    • Sukhotnik, I.1    Mogilner, J.2    Krausz, M.M.3    Lurie, M.4    Hirsh, M.5    Coran, A.G.6
  • 72
    • 84877750156 scopus 로고    scopus 로고
    • Effect of L-arginine on intestinal mucosal immune barrier function in weaned pigs after Escherichia coli LPS challenge
    • 10.1177/1753425912456223, 22904165
    • Zhu H, Liu Y, Xie X, Huang J, Hou Y. Effect of L-arginine on intestinal mucosal immune barrier function in weaned pigs after Escherichia coli LPS challenge. Innate Immun 2013, 19:242-252. 10.1177/1753425912456223, 22904165.
    • (2013) Innate Immun , vol.19 , pp. 242-252
    • Zhu, H.1    Liu, Y.2    Xie, X.3    Huang, J.4    Hou, Y.5
  • 73
    • 30644473517 scopus 로고    scopus 로고
    • Alterations of intestinal immune function and regulatory effects of L-arginine in experimental severe acute pancreatitis rats
    • Qiao SF, Lu TJ, Sun JB, Li F. Alterations of intestinal immune function and regulatory effects of L-arginine in experimental severe acute pancreatitis rats. World J Gastroenterol 2005, 11:6216-6218.
    • (2005) World J Gastroenterol , vol.11 , pp. 6216-6218
    • Qiao, S.F.1    Lu, T.J.2    Sun, J.B.3    Li, F.4
  • 74
    • 0032004595 scopus 로고    scopus 로고
    • Supplemental dietary arginine accelerates intestinal mucosal regeneration and enhances bacterial clearance following radiation enteritis in rats
    • 10.1006/jsre.1997.5231, 9587353
    • Gurbuz AT, Kunzelman J, Ratzer EE. Supplemental dietary arginine accelerates intestinal mucosal regeneration and enhances bacterial clearance following radiation enteritis in rats. J Surg Res 1998, 74:149-154. 10.1006/jsre.1997.5231, 9587353.
    • (1998) J Surg Res , vol.74 , pp. 149-154
    • Gurbuz, A.T.1    Kunzelman, J.2    Ratzer, E.E.3
  • 75
    • 0034076289 scopus 로고    scopus 로고
    • The prophylactic and therapeutic effects of glutamine- and arginine-enriched diets on radiation-induced enteritis in rats
    • 10.1006/jsre.1999.5808, 10729239
    • Ersin S, Tuncyurek P, Esassolak M, Alkanat M, Buke C, Yilmaz M, et al. The prophylactic and therapeutic effects of glutamine- and arginine-enriched diets on radiation-induced enteritis in rats. J Surg Res 2000, 89:121-125. 10.1006/jsre.1999.5808, 10729239.
    • (2000) J Surg Res , vol.89 , pp. 121-125
    • Ersin, S.1    Tuncyurek, P.2    Esassolak, M.3    Alkanat, M.4    Buke, C.5    Yilmaz, M.6
  • 76
    • 0033927611 scopus 로고    scopus 로고
    • Glutamine and arginine: immunonutrients for improved health
    • 10.1097/00005768-200007001-00002, 10910294
    • Field CJ, Johnson I, Pratt VC. Glutamine and arginine: immunonutrients for improved health. Med Sci Sports Exerc 2000, 32:S377-S388. 10.1097/00005768-200007001-00002, 10910294.
    • (2000) Med Sci Sports Exerc , vol.32
    • Field, C.J.1    Johnson, I.2    Pratt, V.C.3
  • 78
    • 75949116439 scopus 로고    scopus 로고
    • Effects of early enteral nutrition supplemented with arginine on intestinal mucosal immunity in severely burned mice
    • 10.1016/j.clnu.2009.07.005, 19783080
    • Fan J, Meng Q, Guo G, Xie Y, Li X, Xiu Y, et al. Effects of early enteral nutrition supplemented with arginine on intestinal mucosal immunity in severely burned mice. Clin Nutr 2010, 29:124-130. 10.1016/j.clnu.2009.07.005, 19783080.
    • (2010) Clin Nutr , vol.29 , pp. 124-130
    • Fan, J.1    Meng, Q.2    Guo, G.3    Xie, Y.4    Li, X.5    Xiu, Y.6
  • 79
    • 33744783686 scopus 로고    scopus 로고
    • L-Arginine stimulates intestinal intraepithelial lymphocyte functions and immune response in chickens orally immunized with live intermediate plus strain of infectious bursal disease vaccine
    • 10.1016/j.vaccine.2006.03.086, 16723175
    • Tayade C, Koti M, Mishra SC. L-Arginine stimulates intestinal intraepithelial lymphocyte functions and immune response in chickens orally immunized with live intermediate plus strain of infectious bursal disease vaccine. Vaccine 2006, 24:5473-5480. 10.1016/j.vaccine.2006.03.086, 16723175.
    • (2006) Vaccine , vol.24 , pp. 5473-5480
    • Tayade, C.1    Koti, M.2    Mishra, S.C.3
  • 80
    • 4243091740 scopus 로고    scopus 로고
    • Effects of arginine supplementation on mucosal immunity in rats with septic peritonitis
    • 10.1016/j.clnu.2003.10.005, 15297092
    • Shang HF, Wang YY, Lai YN, Chiu WC, Yeh SL. Effects of arginine supplementation on mucosal immunity in rats with septic peritonitis. Clin Nutr 2004, 23:561-569. 10.1016/j.clnu.2003.10.005, 15297092.
    • (2004) Clin Nutr , vol.23 , pp. 561-569
    • Shang, H.F.1    Wang, Y.Y.2    Lai, Y.N.3    Chiu, W.C.4    Yeh, S.L.5
  • 81
    • 3042548852 scopus 로고    scopus 로고
    • L-arginine-enriched parenteral nutrition affects lymphocyte phenotypes of gut-associated lymphoid tissue
    • 10.1177/0148607104028004246, 15291406
    • Fukatsu K, Ueno C, Maeshima Y, Hara E, Nagayoshi H, Omata J, et al. L-arginine-enriched parenteral nutrition affects lymphocyte phenotypes of gut-associated lymphoid tissue. JPEN J Parenter Enteral Nutr 2004, 28:246-250. 10.1177/0148607104028004246, 15291406.
    • (2004) JPEN J Parenter Enteral Nutr , vol.28 , pp. 246-250
    • Fukatsu, K.1    Ueno, C.2    Maeshima, Y.3    Hara, E.4    Nagayoshi, H.5    Omata, J.6
  • 82
    • 33646773620 scopus 로고    scopus 로고
    • The effects of sulfur amino acid intake on immune function in humans
    • Grimble RF. The effects of sulfur amino acid intake on immune function in humans. J Nutr 2006, 136:1660S-1665S.
    • (2006) J Nutr , vol.136
    • Grimble, R.F.1
  • 83
    • 22144482049 scopus 로고    scopus 로고
    • Nutritional and functional importance of intestinal sulfur amino acid metabolism
    • Shoveller AK, Stoll B, Ball RO, Burrin DG. Nutritional and functional importance of intestinal sulfur amino acid metabolism. J Nutr 2005, 135:1609-1612.
    • (2005) J Nutr , vol.135 , pp. 1609-1612
    • Shoveller, A.K.1    Stoll, B.2    Ball, R.O.3    Burrin, D.G.4
  • 84
    • 0036124199 scopus 로고    scopus 로고
    • Homocysteine increases monocyte and T-cell adhesion to human aortic endothelial cells
    • 10.1016/S0021-9150(01)00670-0, 11888519
    • Koga T, Claycombe K, Meydani M. Homocysteine increases monocyte and T-cell adhesion to human aortic endothelial cells. Atherosclerosis 2002, 161:365-374. 10.1016/S0021-9150(01)00670-0, 11888519.
    • (2002) Atherosclerosis , vol.161 , pp. 365-374
    • Koga, T.1    Claycombe, K.2    Meydani, M.3
  • 85
    • 66849115545 scopus 로고    scopus 로고
    • Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs
    • 10.1152/ajpendo.91021.2008, 2692405, 19293331
    • Bauchart-Thevret C, Stoll B, Chacko S, Burrin DG. Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs. Am J Physiol Endocrinol Metab 2009, 296:E1239-E1250. 10.1152/ajpendo.91021.2008, 2692405, 19293331.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Bauchart-Thevret, C.1    Stoll, B.2    Chacko, S.3    Burrin, D.G.4
  • 86
    • 69949105948 scopus 로고    scopus 로고
    • L-cysteine supplementation attenuates local inflammation and restores gut homeostasis in a porcine model of colitis
    • 10.1016/j.bbagen.2009.05.018, 19520150
    • Kim CJ, Kovacs-Nolan J, Yang C, Archbold T, Fan MZ, Mine Y. L-cysteine supplementation attenuates local inflammation and restores gut homeostasis in a porcine model of colitis. Biochim Biophys Acta 2009, 1790:1161-1169. 10.1016/j.bbagen.2009.05.018, 19520150.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 1161-1169
    • Kim, C.J.1    Kovacs-Nolan, J.2    Yang, C.3    Archbold, T.4    Fan, M.Z.5    Mine, Y.6
  • 87
    • 0031967119 scopus 로고    scopus 로고
    • Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets
    • Stoll B, Henry J, Reeds PJ, Yu H, Jahoor F, Burrin DG. Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets. J Nutr 1998, 128:606-614.
    • (1998) J Nutr , vol.128 , pp. 606-614
    • Stoll, B.1    Henry, J.2    Reeds, P.J.3    Yu, H.4    Jahoor, F.5    Burrin, D.G.6
  • 89
    • 14944374472 scopus 로고    scopus 로고
    • Dietary threonine restriction specifically reduces intestinal mucin synthesis in rats
    • Faure M, Moennoz D, Montigon F, Mettraux C, Breuille D, Ballevre O. Dietary threonine restriction specifically reduces intestinal mucin synthesis in rats. J Nutr 2005, 135:486-491.
    • (2005) J Nutr , vol.135 , pp. 486-491
    • Faure, M.1    Moennoz, D.2    Montigon, F.3    Mettraux, C.4    Breuille, D.5    Ballevre, O.6
  • 90
    • 46249096043 scopus 로고    scopus 로고
    • Luminal threonine concentration acutely affects intestinal mucosal protein and mucin synthesis in piglets
    • Nichols NL, Bertolo RF. Luminal threonine concentration acutely affects intestinal mucosal protein and mucin synthesis in piglets. J Nutr 2008, 138:1298-1303.
    • (2008) J Nutr , vol.138 , pp. 1298-1303
    • Nichols, N.L.1    Bertolo, R.F.2
  • 91
    • 77951491881 scopus 로고    scopus 로고
    • Optimal dietary true ileal digestible threonine for supporting the mucosal barrier in small intestine of weanling pigs
    • 10.3945/jn.109.118497, 20335627
    • Wang W, Zeng X, Mao X, Wu G, Qiao S. Optimal dietary true ileal digestible threonine for supporting the mucosal barrier in small intestine of weanling pigs. J Nutr 2010, 140:981-986. 10.3945/jn.109.118497, 20335627.
    • (2010) J Nutr , vol.140 , pp. 981-986
    • Wang, W.1    Zeng, X.2    Mao, X.3    Wu, G.4    Qiao, S.5
  • 92
    • 77956651345 scopus 로고    scopus 로고
    • A moderate threonine deficiency affects gene expression profile, paracellular permeability and glucose absorption capacity in the ileum of piglets
    • 10.1016/j.jnutbio.2009.07.004, 19954951
    • Hamard A, Mazurais D, Boudry G, Le Huerou-Luron I, Seve B, Le FN. A moderate threonine deficiency affects gene expression profile, paracellular permeability and glucose absorption capacity in the ileum of piglets. J Nutr Biochem 2010, 21:914-921. 10.1016/j.jnutbio.2009.07.004, 19954951.
    • (2010) J Nutr Biochem , vol.21 , pp. 914-921
    • Hamard, A.1    Mazurais, D.2    Boudry, G.3    Le Huerou-Luron, I.4    Seve, B.5    Le, F.N.6
  • 93
    • 80053135315 scopus 로고    scopus 로고
    • Effect of supplemental L-threonine on mucin 2 gene expression and intestine mucosal immune and digestive enzymes activities of laying hens in environments with high temperature and humidity
    • 10.3382/ps.2011-01574, 21934007
    • Azzam MM, Zou XT, Dong XY, Xie P. Effect of supplemental L-threonine on mucin 2 gene expression and intestine mucosal immune and digestive enzymes activities of laying hens in environments with high temperature and humidity. Poult Sci 2011, 90:2251-2256. 10.3382/ps.2011-01574, 21934007.
    • (2011) Poult Sci , vol.90 , pp. 2251-2256
    • Azzam, M.M.1    Zou, X.T.2    Dong, X.Y.3    Xie, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.