Non-invasive in vivo characterization of microclimate pH inside in situ forming PLGA implants using multispectral fluorescence imaging

Journal of Controlled Release

Volumn 179, Issue 1, 2014, Pages 52-62

  Schädlich, Andreas ^a   Kempe, Sabine ^a   Mäder, Karsten ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

fluorescence imaging; in situ forming implants; in vivo imaging; microclimate pH; pH distribution; PLGA

Indexed keywords

BENZOPYRAN DERIVATIVE; DRUG CARRIER; DRUG IMPLANT; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SNARF DYE; SOLVENT;

ANIMAL; CHEMISTRY; DRUG IMPLANT; ELECTRON SPIN RESONANCE; FLUORESCENCE IMAGING; MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; PROCEDURES; SOLUBILITY;

ANIMALS; BENZOPYRANS; DRUG CARRIERS; DRUG IMPLANTS; ELECTRON SPIN RESONANCE SPECTROSCOPY; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MAGNETIC RESONANCE IMAGING; MICE; OPTICAL IMAGING; POLYGLYCOLIC ACID; SOLUBILITY; SOLVENTS;

EID: 84894427081     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.01.024     Document Type: Article

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