Stability of poly(d,l-lactide-co-glycolide) and leuprolide acetate in in-situ forming drug delivery systems

Journal of Controlled Release

Volumn 115, Issue 2, 2006, Pages 158-167

  Dong, W Y ^a   Korber M ^a   Lopez Esguerra V ^a   Bodmeier, R ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Biodegradable drug delivery systems; Implants; In situ forming microparticles; Leuprolide acetate; Poly(d,l lactide co glycolide); Polymer stability

Indexed keywords

BIODEGRADABLE DRUG DELIVERY SYSTEMS; IN-SITU FORMING MICROPARTICLES; LEUPROLIDE ACETATE; POLY(D,L-LACTIDE-CO-GLYCOLIDE); POLYMER STABILITY;

ACETIC ACID; BIODEGRADATION; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; IMPLANTS (SURGICAL); ORGANIC SOLVENTS;

ORGANIC POLYMERS;

1 METHYL 2 PYRROLIDINONE; 2 PYRROLIDINONE; ACETIC ACID; ACETIC ACID ETHYL ESTER; CITRIC ACID TRIETHYL ESTER; DIMETHYL SULFOXIDE; DIOXANE; LEUPRORELIN; LIDOCAINE; MACROGOL 400; ORGANIC SOLVENT; POLYGLACTIN; RESOMER; SODIUM CHLORIDE; TRIACETIN;

AQUEOUS SOLUTION; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; DRUG DELIVERY SYSTEM; DRUG STABILITY; EMULSION; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STORAGE TEMPERATURE;

CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFERENTIAL THERMAL ANALYSIS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; DRUG STORAGE; FREEZE DRYING; HUMIDITY; LACTIC ACID; LEUPROLIDE; NANOPARTICLES; OILS; POLYGLYCOLIC ACID; POLYMERS; SOLVENTS; TEMPERATURE; WATER;

EID: 33749555615     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.07.013     Document Type: Article

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