How stealthy are PEG-PLA nanoparticles? An NIR in vivo study combined with detailed size measurements

Pharmaceutical Research

Volumn 28, Issue 8, 2011, Pages 1995-2007

  Schädlich, Andreas ^a   Rose, Cornelia ^b   Kuntsche, Judith ^a   Caysa, Henrike ^a   Mueller, Thomas ^a   Göpferich, Achim ^b   Mäder, Karsten ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

AF4; fluorescence imaging; in vivo imaging; nanoparticle; PEG PLA

Indexed keywords

MACROGOL; NANOPARTICLE; POLYLACTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOACCUMULATION; BIOCOMPATIBILITY; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; FIELD FLOW FRACTIONATION; FLUORESCENCE ANALYSIS; IN VIVO STUDY; LIGHT SCATTERING; MALE; MOUSE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; DRUG CARRIERS; DRUG STABILITY; FEMALE; FRACTIONATION, FIELD FLOW; MALE; MICE; MICE, NUDE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; SPECTROSCOPY, NEAR-INFRARED; TISSUE DISTRIBUTION;

EID: 79961171253     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0426-5     Document Type: Article

References (54)

1. I Brigger C Dubernet P Couvreur 2002 Nanoparticles in cancer therapy and diagnosis Adv Drug Deliv Rev. 54 631 51 12204596 10.1016/S0169-409X(02)00044-3 1:CAS:528:DC%2BD38XmsVeqtrs%3D (Pubitemid 35247520)
2. D Peer JM Karp S Hong OC FaroKHzad R Margalit R Langer 2007 Nanocarriers as an emerging platform for cancer therapy Nature Nanotech. 2 751 60 10.1038/nnano.2007.387 1:CAS:528:DC%2BD2sXhtlyktL%2FI (Pubitemid 350223348)
3. H Maeda 2010 Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospects Bioconjugate Chem. 21 797 802 10.1021/bc100070g 1:CAS:528:DC%2BC3cXkvVKrtLw%3D
4. F Yuan M Dellian D Fukumura M Leunig DA Berk VP Torchilin, et al. 1995 Vascular-permeability in a human tumor xenograft - molecular-size dependence and cutoff size Cancer Res. 55 3752 6 7641188 1:CAS:528:DyaK2MXnvVelsLc%3D
5. SK Hobbs WL Monsky F Yuan WG Roberts L Griffith VP Torchilin, et al. 1998 Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment Proc Natl Acad Sci USA 95 4607 12 9539785 10.1073/pnas.95.8. 4607 1:CAS:528:DyaK1cXis1OgsLc%3D (Pubitemid 28207960)
6. SM Moghimi CJH Porter IS Muir L Illum SS Davis 1991 Non-phagocytic uptake of intravenously injected microspheres in rat spleen - influence of particle-size and hydrophilic coating Biochem Biophys Res Commun. 177 861 6 2049107 10.1016/0006-291X(91)91869-E 1:CAS:528:DyaK3MXksFOjt7w%3D
7. SM Moghimi AC Hunter JC Murray 2001 Long-circulating and target-specific nanoparticles: theory to practice Pharmacol Rev. 53 283 318 11356986 1:CAS:528:DC%2BD3MXkt1Gnurc%3D (Pubitemid 32476118)
8. R Nakaoka Y Tabata T Yamaoka Y Ikada 1997 Prolongation of the serum half-life period of superoxide dismutase by poly(ethylene glycol) modification J Controlled Release. 46 253 61 10.1016/S0168-3659(96)01605-7 1:CAS:528:DyaK2sXhtlyhsbk%3D (Pubitemid 27132849)
9. DC Litzinger AMJ Buiting N Vanrooijen L Huang 1994 Effect of liposome size on the circulation time and intraorgan distribution of amphipathic Poly(Ethylene Glycol)-Containing Liposomes Biochim Biophys Acta, Biomembr 1190 99 107 10.1016/0005-2736(94)90038-8 1:CAS:528:DyaK2cXit1Klurc%3D (Pubitemid 24066264)
10. DX Liu A Mori L Huang 1992 Role of liposome size and res blockade in controlling biodistribution and tumor uptake of Gm1-containing liposomes Biochim Biophys Acta. 1104 95 101 1550858 10.1016/0005-2736(92)90136-A 1:CAS:528:DyaK38XhsFyktrY%3D
11. G Storm SO Belliot T Daemen DD Lasic 1995 Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system Adv Drug Deliv Rev. 17 31 48 10.1016/0169-409X(95)00039-A 1:CAS:528:DyaK2MXps1Wltbk%3D
12. M Gaumet A Vargas R Gurny F Delie 2008 Nanoparticles for drug delivery: the need for precision in reporting particle size parameters Eur J Pharm Biopharm. 69 1 9 17826969 10.1016/j.ejpb.2007.08.001 1:CAS:528: DC%2BD1cXktlGlt7w%3D (Pubitemid 351467152)
13. SE Dunn AGA Coombes MC Garnett SS Davis MC Davies L Illum 1997 In vitro cell interaction and in vivo biodistribution of poly(lactide-co-glycolide) nanospheres surface modified by poloxamer and poloxamine copolymers J Controlled Release. 44 65 76 10.1016/S0168-3659(96)01504-0 1:CAS:528:DyaK28XmvFeiur8%3D (Pubitemid 27051335)
14. GS Kwon K Kataoka 1995 Block-copolymer micelles as long-circulating drug vehicles Adv Drug Deliv Rev. 16 295 309 10.1016/0169-409X(95)00031-2 1:CAS:528:DyaK2MXpt1amt70%3D
15. AFE Hezinger J Tessmar A Gopferich 2008 Polymer coating of quantum dots-A powerful tool toward diagnostics and sensorics Eur J Pharm Biopharm. 68 138 52 17689938 10.1016/j.ejpb.2007.05.013 1:CAS:528:DC%2BD2sXhsVSgtb3J (Pubitemid 350181411)
16. IL Medintz HT Uyeda ER Goldman H Mattoussi 2005 Quantum dot bioconjugates for imaging, labelling and sensing Nature Mater. 4 435 46 10.1038/nmat1390 1:CAS:528:DC%2BD2MXks1Cit7k%3D (Pubitemid 40774047)
17. AM Smith HW Duan AM Mohs SM Nie 2008 Bioconjugated quantum dots for in vivo molecular and cellular imaging Adv Drug Deliv Rev. 60 1226 40 18495291 10.1016/j.addr.2008.03.015 1:CAS:528:DC%2BD1cXosVOnsrw%3D
18. JV Frangioni 2003 In vivo near-infrared fluorescence imaging Curr Opin Chem Biol. 7 626 34 14580568 10.1016/j.cbpa.2003.08.007 1:CAS:528: DC%2BD3sXot12hsL0%3D (Pubitemid 37315800)
19. AM Derfus WCW Chan SN Bhatia 2004 Probing the cytotoxicity of semiconductor quantum dots Nano Lett. 4 11 8 10.1021/nl0347334 1:CAS:528:DC%2BD3sXps1SmtLo%3D (Pubitemid 38167855)
20. A Lucke J Tessmar E Schnell G Schmeer A Gopferich 2000 Biodegradable poly(D, L-lactic acid)-poly(ethylene glycol)-monomethyl ether diblock copolymers: structures and surface properties relevant to their use as biomaterials Biomaterials. 21 2361 70 11055283 10.1016/S0142-9612(00)00103-4 1:CAS:528:DC%2BD3cXmslKmt78%3D
21. H Fessi F Puisieux JP Devissaguet N Ammoury S Benita 1989 Nanocapsule formation by interfacial polymer deposition following solvent displacement Int J Pharm. 55 R1 4 10.1016/0378-5173(89)90281-0 1:CAS:528:DyaL1MXmtF2hsbs%3D (Pubitemid 19247505)
22. Rose C. Particulate systems for Fluorescence Imaging and Drug Delivery. Thesis: University of Regensburg; 2010.
23. J Kuntsche K Klaus F Steiniger 2009 Size determinations of colloidal fat emulsions: a comparative study J Biomed Nanotechnol. 5 384 95 20055084 10.1166/jbn.2009.1047 1:CAS:528:DC%2BD1MXhtlKnu7vE
24. U Westedt M Kalinowski M Wittmar T Merdan F Unger J Fuchs, et al. 2007 Poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment J Controlled Release. 119 41 51 10.1016/j.jconrel.2007.01.009 1:CAS:528:DC%2BD2sXksVejtLo%3D (Pubitemid 46561540)
25. T Mosmann 1983 Rapid colorimetric assay for cellular growth and survival-Application to proliferation and cyto-toxicity assays J Immunol Methods. 65 55 63 6606682 10.1016/0022-1759(83)90303-4 1:STN:280: DyaL2c%2FovFSmtw%3D%3D (Pubitemid 14203433)
26. BS Schaffer MH Grayson JM Wortham CB Kubicek AT McCleish SI Prajapati, et al. 2010 Immune competency of a hairless mouse strain for improved preclinical studies in genetically engineered mice Mol Cancer Ther. 9 2354 64 20663932 10.1158/1535-7163.MCT-10-0207 1:CAS:528:DC%2BC3cXpvVOjtrs%3D
27. F Leblond SC Davis PA Valdes BW Pogue 2010 Pre-clinical whole-body fluorescence imaging: review of instruments, methods and applications J Photoch Photobio B. 98 77 94 10.1016/j.jphotobiol.2009.11.007 1:CAS:528: DC%2BC3cXksVWgsA%3D%3D
28. Mansfield JR, Gossage KW, Hoyt CC, Levenson RM. Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging. J Biomed Opt. 2005;10.
29. T Zimmermann J Rietdorf R Pepperkok 2003 Spectral imaging and its applications in live cell microscopy FEBS Lett. 546 87 92 12829241 10.1016/S0014-5793(03)00521-0 1:CAS:528:DC%2BD3sXkvVKjs70%3D (Pubitemid 36782286)
30. FY Cheng SPH Wang CH Su TL Tsai PC Wu DB Shieh, et al. 2008 Stabilizer-free poly(lactide-co-glycolide) nanoparticles for multimodal biomedical probes Biomaterials. 29 2104 12 18276001 10.1016/j.biomaterials.2008. 01.010 1:CAS:528:DC%2BD1cXivFKntLs%3D
31. JL Putaux A Buleon R Borsali H Chanzy 1999 Ultrastructural aspects of phytoglycogen from cryo-transmission electron microscopy and quasi-elastic light scattering data Int J Biol Macromol. 26 145 50 10517521 10.1016/S0141-8130(99) 00076-8 1:CAS:528:DyaK1MXntVWlsrw%3D (Pubitemid 29428244)
32. J Lohrke A Briel K Mader 2008 Characterization of superparamagnetic iron oxide nanoparticles by asymmetrical flow-field-flow-fractionation Nanomedicine. 3 437 52 18694306 10.2217/17435889.3.4.437 1:CAS:528:DC%2BD1cXhtVWnsL7N
33. O Stauch R Schubert G Savin W Burchard 2002 Structure of artificial cytoskeleton containing liposomes in aqueous solution studied by static and dynamic light scattering Biomacromolecules. 3 565 78 12005530 10.1021/bm0200074 1:CAS:528:DC%2BD38XivVOjsrc%3D (Pubitemid 34567462)
34. MD Coffin JW Mcginity 1992 Biodegradable pseudolatexes-the chemical-stability of Poly(D, L-Lactide) and poly (Epsilon-Caprolactone) nanoparticles in aqueous-media Pharm Res. 9 200 5 1553342 10.1023/A: 1018981222092 1:CAS:528:DyaK38XhsFyktbY%3D
35. M Dunne OI Corrigan Z Ramtoola 2000 Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles Biomaterials. 21 1659 68 10905407 10.1016/S0142-9612(00)00040-5 1:CAS:528:DC%2BD3cXksF2murw%3D (Pubitemid 30347308)
36. WJ Lin YC Chen CC Lin CF Chen JW Chen 2006 Characterization of pegylated copolymeric micelles and in vivo pharmacokinetics and biodistribution studies J Biomed Mater Res Part B. 77B 188 94 10.1002/jbm.b.30418 1:CAS:528: DC%2BD28XjsFCgsrw%3D
37. MG Honig RI Hume 1986 Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures J Cell Biol. 103 171 87 2424918 10.1083/jcb.103.1.171 1:CAS:528:DyaL28XltlSitb8%3D (Pubitemid 16067002)
38. Texier I, Goutayer M, Da Silva A, Guyon L, Djaker N, Josserand V, et al. Cyanine-loaded lipid nanoparticles for improved in vivo fluorescence imaging. J Biomed Opt. 2009;14.
39. J Chen IR Corbin H Li WG Cao JD Glickson G Zheng 2007 Ligand conjugated low-density lipoprotein nanoparticles for enhanced optical cancer imaging in vivo J Am Chem Soc. 129 5798 17428054 10.1021/ja069336k 1:CAS:528: DC%2BD2sXktFegs7g%3D (Pubitemid 46748467)
40. DP Kuffler 1990 Long-term survival and sprouting in culture by motoneurons isolated from the spinal-cord of adult frogs J Comp Neurol. 302 729 38 1707066 10.1002/cne.903020405 1:STN:280:DyaK3M7osFKlsw%3D%3D
41. R Weissleder 2001 A clearer vision for in vivo imaging Nat Biotechnol. 19 316 7 11283581 10.1038/86684 1:CAS:528:DC%2BD3MXis1SmsLg%3D
42. Hardin J. Confocal and multi-photon imaging of living embryos. In Pawley JB, Masters BR, editors. Handbook of biological confocal microscopy. J Biomed Opt. 2008;760.
43. K Jores A Haberland S Wartewig K Mader W Mehnert 2005 Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and raman spectroscopy Pharm Res. 22 1887 97 16132349 10.1007/s11095-005-7148-5 1:CAS:528:DC%2BD2MXhtFChs7bI (Pubitemid 41504342)
44. S Petersen A Fahr H Bunjes 2010 Flow cytometry as a new approach to investigate drug transfer between lipid particles Mol Pharmaceutics. 7 350 63 10.1021/mp900130s 1:CAS:528:DC%2BC3cXhs1agtbY%3D
45. N.n. Public Chemical Database. Public Chemical Database. 2010.
46. P Greenspan EP Mayer SD Fowler 1985 Nile red-A selective fluorescent stain for intracellular lipid droplets J Cell Biol. 100 965 73 3972906 10.1083/jcb.100.3.965 1:CAS:528:DyaL2MXhsVGmtb4%3D (Pubitemid 15135357)
47. F Rashid RW Horobin MA Williams 1991 Predicting the behaviour and selectivity of fluorescent probes for lysosomes and related structures by means of structure-activity models Histochem J. 23 450 9 1743993 10.1007/BF01041375 1:CAS:528:DyaK38Xhs12gsb0%3D
48. F Rashid RW Horobin 1990 Interaction of molecular probes with living cells and tissues.2. A structure-activity analysis of mitochondrial staining by cationic probes, and a discussion of the synergistic nature of image-based and biochemical approaches Histochem Cell Biol. 94 303 8 1:CAS:528: DyaK3cXkvFCisbo%3D (Pubitemid 20212010)
49. AI Ivanov VB Gavrilov DA Furmanchuk O Aleinikova SV Konev GV Kaler 2002 Fluorescent probing of the ligand-binding ability of blood plasma in the acute-phase response Clin Exp Med. 2 147 55 12447613 10.1007/s102380200021 1:CAS:528:DC%2BD38XovFSitro%3D (Pubitemid 35439568)
50. S Gordon RD Tee AJN Taylor 1993 Analysis of rat urine proteins and allergens by sodium Dodecyl-Sulfate Polyacrylamide-Gel electrophoresis and immunoblotting J Allergy Clin Immun. 92 298 305 8349940 10.1016/0091-6749(93) 90173-D 1:STN:280:DyaK3szlt12rtA%3D%3D (Pubitemid 23254118)
51. HJ Lim MJ Parr D Masin NL McIntosh TD Madden GY Zhang, et al. 2000 Kupffer cells do not play a role in governing the efficacy of liposomal mitoxantrone used to treat a tumor model designed to assess drug delivery to liver Clin Cancer Res. 6 4449 60 11106266 1:CAS:528:DC%2BD3cXovVSnsr8%3D
52. D Bazile C Prudhomme MT Bassoullet M Marlard G Spenlehauer M Veillard 1995 Stealth Me.Peg-Pla nanoparticles avoid uptake by the mononuclear phagocytes system J Pharm Sci. 84 493 8 7629743 10.1002/jps.2600840420 1:CAS:528:DyaK2MXkvVCmtr0%3D
53. T Verrecchia G Spenlehauer DV Bazile A Murrybrelier Y Archimbaud M Veillard 1995 Non-stealth (Poly(Lactic Acid Albumin)) and stealth (Poly(Lactic Acid-Polyethylene Glycol)) nanoparticles as injectable drug carriers J Controlled Release. 36 49 61 10.1016/0168-3659(95)00053-B 1:CAS:528: DyaK2MXotVartLs%3D
54. R Gref G Miralles E Dellacherie 1999 Polyoxyethylene-coated nanospheres: effect of coating on zeta potential and phagocytosis Polym Int. 48 251 6 10.1002/(SICI)1097-0126(199904)48:4<251::AID-PI104>3.0.CO;2-4 1:CAS:528:DyaK1MXjtVSmtbY%3D