Monitoring of internal pH gradients within multi-layer tablets by optical methods and EPR imaging

International Journal of Pharmaceutics

Volumn 417, Issue 1-2, 2011, Pages 204-215

  Eisenächer, Friederike ^a   Schädlich, Andreas ^a   Mäder, Karsten ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Benchtop NMR; EPR; MRI; Multi layer tablet; pH dependent solubility; Weakly acidic drug

Indexed keywords

DYE; EXCIPIENT; KETOPROFEN; METFORMIN; POVIDONE;

ARTICLE; DRUG RELEASE; ELECTRON SPIN RESONANCE; FLUORESCENCE; HUMAN; HYDRATION; LIPOPHILICITY; MONITORING; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; PRIORITY JOURNAL; TABLET;

CHEMISTRY, PHARMACEUTICAL; COLORING AGENTS; DRUG DELIVERY SYSTEMS; ELECTRON SPIN RESONANCE SPECTROSCOPY; MAGNETIC RESONANCE IMAGING; PROTON-MOTIVE FORCE; SOLUBILITY; SPECTROMETRY, FLUORESCENCE; TABLETS;

EID: 80052274168     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.10.010     Document Type: Article

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