메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Protective properties of radio-chemoresistant glioblastoma stem cell clones are associated with metabolic adaptation to reduced glucose dependence

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION, PHYSIOLOGICAL; CELL LINE, TUMOR; DACARBAZINE; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION; GLIOBLASTOMA; GLUCOSE; HUMANS; SIGNAL TRANSDUCTION; STEM CELLS; STRESS, PHYSIOLOGICAL; UP-REGULATION;

EID: 84894202266     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080397     Document Type: Article
Times cited : (48)

References (57)
  • 1
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-Year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, et al. (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10: 459-466.
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    Van Den Bent, M.J.4    Taphoorn, M.J.5
  • 3
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, et al. (2004) Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64: 7011-7021.
    • (2004) Cancer Res , vol.64 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3    Cipelletti, B.4    Gritti, A.5
  • 4
    • 11244293572 scopus 로고    scopus 로고
    • Isolation of cancer stem cells from adult glioblastoma multiforme
    • Yuan X, Curtin J, Xiong Y, Liu G, Waschsmann-Hogiu S, et al. (2004) Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23: 9392-9400.
    • (2004) Oncogene , vol.23 , pp. 9392-9400
    • Yuan, X.1    Curtin, J.2    Xiong, Y.3    Liu, G.4    Waschsmann-Hogiu, S.5
  • 6
    • 33845610993 scopus 로고    scopus 로고
    • Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
    • Piccirillo SG, Reynolds BA, Zanetti N, Lamore G, Binda E, et al. (2006) Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature 444: 761-765.
    • (2006) Nature , vol.444 , pp. 761-765
    • Piccirillo, S.G.1    Reynolds, B.A.2    Zanetti, N.3    Lamore, G.4    Binda, E.5
  • 7
    • 66049159086 scopus 로고    scopus 로고
    • Molecular properties of CD133 + glioblastoma stem cells derived from treatment-refractory recurrent brain tumors
    • Liu Q, Nguyen DH, Dong Q, Shitaku P, Chung K, Liu OY, et al (2009) Molecular properties of CD133 + glioblastoma stem cells derived from treatment-refractory recurrent brain tumors. J Neurooncol 94:1-19.
    • (2009) J Neurooncol , vol.94 , pp. 1-19
    • Liu, Q.1    Nguyen, D.H.2    Dong, Q.3    Shitaku, P.4    Chung, K.5    Liu, O.Y.6
  • 8
    • 70349949070 scopus 로고    scopus 로고
    • Modulation of invasive properties of CD133+ glioblastoma stem cells: A role for MT1-MMP in bioactive lysophospholipid signaling
    • Annabi B, Lachambre MP, Plouffe K, Sartelet H, Béliveau R (2009) Modulation of invasive properties of CD133+ glioblastoma stem cells: a role for MT1-MMP in bioactive lysophospholipid signaling. Mol Carcinog 48: 910-919.
    • (2009) Mol Carcinog , vol.48 , pp. 910-919
    • Annabi, B.1    Lachambre, M.P.2    Plouffe, K.3    Sartelet, H.4    Béliveau, R.5
  • 9
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, et al. (2006) Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5
  • 11
    • 46449115281 scopus 로고    scopus 로고
    • Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
    • Murat A, Migliavacca E, Gorlia T, Lambiv WL, Shay T, et al. (2008) Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J Clin Oncol 26: 3015-3024.
    • (2008) J Clin Oncol , vol.26 , pp. 3015-3024
    • Murat, A.1    Migliavacca, E.2    Gorlia, T.3    Lambiv, W.L.4    Shay, T.5
  • 12
    • 77955381770 scopus 로고    scopus 로고
    • BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery
    • Facchino S, Abdouh M, Chatoo W, Bernier G (2010) BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J Neurosci 30: 10096-10111.
    • (2010) J Neurosci , vol.30 , pp. 10096-10111
    • Facchino, S.1    Abdouh, M.2    Chatoo, W.3    Bernier, G.4
  • 14
    • 77956294442 scopus 로고    scopus 로고
    • Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence
    • Gilbert CA, Daou MC, Moser RP, Ross AH (2010) Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence. Cancer Res 70: 6870-6879.
    • (2010) Cancer Res , vol.70 , pp. 6870-6879
    • Gilbert, C.A.1    Daou, M.C.2    Moser, R.P.3    Ross, A.H.4
  • 16
    • 67650485853 scopus 로고    scopus 로고
    • Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma
    • Vellanki SH, Grabrucker A, Liebau S, Proepper C, Eramo A, et al. (2009) Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma. Neoplasia 11: 743-752.
    • (2009) Neoplasia , vol.11 , pp. 743-752
    • Vellanki, S.H.1    Grabrucker, A.2    Liebau, S.3    Proepper, C.4    Eramo, A.5
  • 17
    • 70350150304 scopus 로고    scopus 로고
    • Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma
    • Nakai E, Park K, Yawata T, Chihara T, Kumazawa A, et al. (2009) Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma. Cancer Invest 27: 901-908.
    • (2009) Cancer Invest , vol.27 , pp. 901-908
    • Nakai, E.1    Park, K.2    Yawata, T.3    Chihara, T.4    Kumazawa, A.5
  • 18
    • 60849117508 scopus 로고    scopus 로고
    • PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
    • Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, et al. (2009) PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4: 226-235.
    • (2009) Cell Stem Cell , vol.4 , pp. 226-235
    • Bleau, A.M.1    Hambardzumyan, D.2    Ozawa, T.3    Fomchenko, E.I.4    Huse, J.T.5
  • 19
    • 69349095324 scopus 로고    scopus 로고
    • CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines
    • McCord AM, Jamal M, Williams ES, Camphausen K, Tofilon PJ (2009) CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines. Clin Cancer Res 15: 5145-5153.
    • (2009) Clin Cancer Res , vol.15 , pp. 5145-5153
    • McCord, A.M.1    Jamal, M.2    Williams, E.S.3    Camphausen, K.4    Tofilon, P.J.5
  • 20
    • 62549142665 scopus 로고    scopus 로고
    • Comparative analysis of DNA repair in stem and nonstem glioma cell cultures
    • Ropolo M, Daga A, Griffero F, Foresta M, Casartelli G, et al. (2009) Comparative analysis of DNA repair in stem and nonstem glioma cell cultures. Mol Cancer Res 7: 383-392.
    • (2009) Mol Cancer Res , vol.7 , pp. 383-392
    • Ropolo, M.1    Daga, A.2    Griffero, F.3    Foresta, M.4    Casartelli, G.5
  • 21
    • 14044276801 scopus 로고    scopus 로고
    • Evidence for beneficial low level radiation effects and radiation hormesis
    • Feinendegen LE (2005) Evidence for beneficial low level radiation effects and radiation hormesis. Br J Radiol 78: 3-7.
    • (2005) Br J Radiol , vol.78 , pp. 3-7
    • Feinendegen, L.E.1
  • 22
    • 0037434705 scopus 로고    scopus 로고
    • Toxicology rethinks its central belief
    • Calabrese EJ, Baldwin LA (2003) Toxicology rethinks its central belief. Nature 421: 691-692.
    • (2003) Nature , vol.421 , pp. 691-692
    • Calabrese, E.J.1    Baldwin, L.A.2
  • 23
    • 0033304082 scopus 로고    scopus 로고
    • Cellular signal adaptation with damage control at low doses versus the predominance of DNA damage at high doses
    • Feinendegen LE, Bond VP, Sondhaus CA, Altman KI (1999) Cellular signal adaptation with damage control at low doses versus the predominance of DNA damage at high doses. C R Acad Sci III 322: 245-251.
    • (1999) C R Acad Sci III , vol.322 , pp. 245-251
    • Feinendegen, L.E.1    Bond, V.P.2    Sondhaus, C.A.3    Altman, K.I.4
  • 24
  • 25
    • 46649112964 scopus 로고    scopus 로고
    • "Adaptive response" - Some underlying mechanisms and open questions
    • Dimova EG, Bryant PE, Chankova SG (2008) "Adaptive response" - Some underlying mechanisms and open questions. Genet Mol Biol 31: 396-408.
    • (2008) Genet Mol Biol , vol.31 , pp. 396-408
    • Dimova, E.G.1    Bryant, P.E.2    Chankova, S.G.3
  • 26
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span - From yeast to humans
    • Fontana L, Partridge L, Longo VD (2010) Extending healthy life span - from yeast to humans. Science 328: 321-326.
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 27
  • 28
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • Blüher M, Kahn BB, Kahn CR (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299: 572-574.
    • (2003) Science , vol.299 , pp. 572-574
    • Blüher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 29
    • 27744511769 scopus 로고    scopus 로고
    • Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
    • Kaeberlein M, Powers RW 3rd, Steffen KK, Westman EA, Hu D, et al. (2005) Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310: 1193-1196.
    • (2005) Science , vol.310 , pp. 1193-1196
    • Kaeberlein, M.1    Powers III, R.W.2    Steffen, K.K.3    Westman, E.A.4    Hu, D.5
  • 30
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life and upon the ultimate body size
    • McCay CM, Crowell MF, Maynard LA (1935) The effect of retarded growth upon the length of life and upon the ultimate body size. J. Nutr 10: 63-79.
    • (1935) J. Nutr , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 31
    • 0000847978 scopus 로고    scopus 로고
    • Gene-expression profile of the ageing brain in mice
    • Lee CK, Weindruch R, Prolla TA (2000) Gene-expression profile of the ageing brain in mice. Nat Genet 25:294-297.
    • (2000) Nat Genet , vol.25 , pp. 294-297
    • Lee, C.K.1    Weindruch, R.2    Prolla, T.A.3
  • 32
    • 77952548782 scopus 로고    scopus 로고
    • How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
    • Review
    • Ristow M, Zarse K (2010) How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). Exp Gerontol 45: 410-418. Review.
    • (2010) Exp Gerontol , vol.45 , pp. 410-418
    • Ristow, M.1    Zarse, K.2
  • 33
    • 35948982621 scopus 로고    scopus 로고
    • The role of autophagy in aging: Its essential part in the anti-aging mechanism of caloric restriction
    • Bergamini E, Cavallini G, Donati A, Gori Z (2007) The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction. Ann N Y Acad Sci 1114: 69-78.
    • (2007) Ann N Y Acad Sci , vol.1114 , pp. 69-78
    • Bergamini, E.1    Cavallini, G.2    Donati, A.3    Gori, Z.4
  • 34
    • 28844469898 scopus 로고    scopus 로고
    • Increase in activity during calorie restriction requires Sirt1
    • Chen D, Steele AD, Lindquist S, Guarente L (2005) Increase in activity during calorie restriction requires Sirt1. Science 310: 1641.
    • (2005) Science , vol.310 , pp. 1641
    • Chen, D.1    Steele, A.D.2    Lindquist, S.3    Guarente, L.4
  • 35
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
    • Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, et al. (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434: 113-118.
    • (2005) Nature , vol.434 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5
  • 36
    • 0037353433 scopus 로고    scopus 로고
    • Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline
    • Amst
    • Cabelof DC, Yanamadala S, Raffoul JJ, Guo Z, Soofi A, et al. (2003) Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline. DNA Repair (Amst) 2: 295-307.
    • (2003) DNA Repair , vol.2 , pp. 295-307
    • Cabelof, D.C.1    Yanamadala, S.2    Raffoul, J.J.3    Guo, Z.4    Soofi, A.5
  • 37
    • 80054850434 scopus 로고    scopus 로고
    • Calorie restriction (CR) reduces age-dependent decline of non-homologous end joining (NHEJ) activity in rat tissues
    • Lee JE, Heo JI, Park SH, Kim JH, Kho YJ, et al. (2011) Calorie restriction (CR) reduces age-dependent decline of non-homologous end joining (NHEJ) activity in rat tissues. Exp Gerontol 46: 891-896.
    • (2011) Exp Gerontol , vol.46 , pp. 891-896
    • Lee, J.E.1    Heo, J.I.2    Park, S.H.3    Kim, J.H.4    Kho, Y.J.5
  • 38
    • 4043079846 scopus 로고    scopus 로고
    • Aging intervention, prevention, and therapy through hormesis
    • Rattan SI (2004) Aging intervention, prevention, and therapy through hormesis. J Gerontol A Biol Sci Med Sci 59: 705-709.
    • (2004) J Gerontol a Biol Sci Med Sci , vol.59 , pp. 705-709
    • Rattan, S.I.1
  • 39
    • 0031984854 scopus 로고    scopus 로고
    • Hormesis and the antiaging action of dietary restriction
    • Masoro EJ (1998) Hormesis and the antiaging action of dietary restriction. Exp. Gerontol 31: 61-66.
    • (1998) Exp. Gerontol , vol.31 , pp. 61-66
    • Masoro, E.J.1
  • 41
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, et al. (2009) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 19: 17:98-110.
    • (2009) Cancer Cell , vol.19 , Issue.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5
  • 42
    • 84055182507 scopus 로고    scopus 로고
    • Autocrine endothelin-3/ endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells
    • Liu Y, Ye F, Yamada K, Tso JL, Zhang Y, et al. (2011). Autocrine endothelin-3/ endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells. Mol Cancer Res. 9:1668-85.
    • (2011) Mol Cancer Res , vol.9 , pp. 1668-1685
    • Liu, Y.1    Ye, F.2    Yamada, K.3    Tso, J.L.4    Zhang, Y.5
  • 43
    • 67349276169 scopus 로고    scopus 로고
    • AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
    • Cantó C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, et al. (2009) AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458: 1056-1060.
    • (2009) Nature , vol.458 , pp. 1056-1060
    • Cantó, C.1    Gerhart-Hines, Z.2    Feige, J.N.3    Lagouge, M.4    Noriega, L.5
  • 44
    • 3142740860 scopus 로고    scopus 로고
    • Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
    • Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, et al. (2004) Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305: 390-392.
    • (2004) Science , vol.305 , pp. 390-392
    • Cohen, H.Y.1    Miller, C.2    Bitterman, K.J.3    Wall, N.R.4    Hekking, B.5
  • 45
    • 53149137486 scopus 로고    scopus 로고
    • Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
    • Wang RH, Sengupta K, Li C, Kim HS, Cao L, et al. (2008) Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14: 312-323.
    • (2008) Cancer Cell , vol.14 , pp. 312-323
    • Wang, R.H.1    Sengupta, K.2    Li, C.3    Kim, H.S.4    Cao, L.5
  • 46
    • 84878151308 scopus 로고    scopus 로고
    • Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3
    • Mao P, Joshi K, Li J, Kim SH, Li P, et al. (2013) Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3. Proc Natl Acad Sci U S A. 110:8644-8649.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 8644-8649
    • Mao, P.1    Joshi, K.2    Li, J.3    Kim, S.H.4    Li, P.5
  • 47
  • 48
    • 84865700769 scopus 로고    scopus 로고
    • Stress resistance in the naked mole-rat: The bare essentials - A mini-review
    • Lewis KN, Mele J, Hornsby PJ, Buffenstein R (2012) Stress resistance in the naked mole-rat: the bare essentials - a mini-review. Gerontology 58:453.
    • (2012) Gerontology , vol.58 , pp. 453
    • Lewis, K.N.1    Mele, J.2    Hornsby, P.J.3    Buffenstein, R.4
  • 49
    • 73149086166 scopus 로고    scopus 로고
    • Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse
    • Swindell WR (2009) Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse. BMC Genomics 10: 585.
    • (2009) BMC Genomics , vol.10 , pp. 585
    • Swindell, W.R.1
  • 50
    • 67650095390 scopus 로고    scopus 로고
    • The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells
    • Lomonaco SL, Finniss S, Xiang C, Decarvalho A, Umansky F, et al. (2009) The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells. Int J Cancer 125: 717-722.
    • (2009) Int J Cancer , vol.125 , pp. 717-722
    • Lomonaco, S.L.1    Finniss, S.2    Xiang, C.3    Decarvalho, A.4    Umansky, F.5
  • 51
    • 84864200812 scopus 로고    scopus 로고
    • The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells
    • Komurov K, Tseng JT, Muller M, Seviour EG, Moss TJ, et al. (2012) The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells. Mol Syst Biol 8: 596.
    • (2012) Mol Syst Biol , vol.8 , pp. 596
    • Komurov, K.1    Tseng, J.T.2    Muller, M.3    Seviour, E.G.4    Moss, T.J.5
  • 52
    • 84866274799 scopus 로고    scopus 로고
    • Fasting enhances the response of glioma to chemo- And radiotherapy
    • Safdie F, Brandhorst S, Wei M, Wang W, Lee C, et al. (2012) Fasting enhances the response of glioma to chemo- and radiotherapy. PLoS One 7:e44603.
    • (2012) PLoS One , vol.7
    • Safdie, F.1    Brandhorst, S.2    Wei, M.3    Wang, W.4    Lee, C.5
  • 53
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z, Bao S, Wu Q, Wang H, Eyler C et al. (2009) Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15:501-513.
    • (2009) Cancer Cell , vol.15 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3    Wang, H.4    Eyler, C.5
  • 55
    • 78650747994 scopus 로고    scopus 로고
    • SIRT1 contributes to telomere maintenance and augments global homologous recombination
    • Palacios JA, Herranz D, De Bonis ML, Velasco S, Serrano M (2010) SIRT1 contributes to telomere maintenance and augments global homologous recombination. J Cell Biol 191: 1299-1313.
    • (2010) J Cell Biol , vol.191 , pp. 1299-1313
    • Palacios, J.A.1    Herranz, D.2    De Bonis, M.L.3    Velasco, S.4    Serrano, M.5
  • 56
    • 53749087325 scopus 로고    scopus 로고
    • Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
    • Chen ZH, Kim HP, Sciurba FC, Lee SJ, Feghali-Bostwick C, et al. (2008) Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One 3: e3316.
    • (2008) PLoS One , vol.3
    • Chen, Z.H.1    Kim, H.P.2    Sciurba, F.C.3    Lee, S.J.4    Feghali-Bostwick, C.5
  • 57
    • 78951491794 scopus 로고    scopus 로고
    • Induction of Sirt1 by mechanical stretch of skeletal muscle through the early response factor EGR1 triggers an antioxidative response
    • Pardo PS, Mohamed JS, Lopez MA, Boriek AM (2011) Induction of Sirt1 by mechanical stretch of skeletal muscle through the early response factor EGR1 triggers an antioxidative response. J Biol Chem 286: 2559-2566.
    • (2011) J Biol Chem , vol.286 , pp. 2559-2566
    • Pardo, P.S.1    Mohamed, J.S.2    Lopez, M.A.3    Boriek, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.