메뉴 건너뛰기




Volumn 120, Issue , 2014, Pages 175-185

Neuroprotective effects of the cannabinoid agonist HU210 on retinal degeneration

Author keywords

Apoptosis; Confocal microscopy; Electroretinography; Immunohistochemistry; Neurodegeneration; P23H; Retinitis pigmentosa

Indexed keywords

APOPTOSIS; CONFOCAL MICROSCOPY; ELECTRORETINOGRAPHY; IMMUNOHISTOCHEMISTRY; NEURODEGENERATION; P23H; RETINITIS PIGMENTOSA;

EID: 84894088824     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2014.01.019     Document Type: Article
Times cited : (54)

References (81)
  • 1
    • 14644401785 scopus 로고    scopus 로고
    • Decreased glutathione transferase levels in rd1/rd1 mouse retina: replenishment protects photoreceptors in retinal explants
    • Ahuja P., Caffe A.R., Ahuja S., Ekstrom P., van Veen T. Decreased glutathione transferase levels in rd1/rd1 mouse retina: replenishment protects photoreceptors in retinal explants. Neuroscience 2005, 131:935-943.
    • (2005) Neuroscience , vol.131 , pp. 935-943
    • Ahuja, P.1    Caffe, A.R.2    Ahuja, S.3    Ekstrom, P.4    van Veen, T.5
  • 2
    • 0026089384 scopus 로고
    • Ocular findings in patients with autosomal dominant retinitis pigmentosa and a rhodopsin gene defect (Pro-23-His)
    • Berson E.L., Rosner B., Sandberg M.A., Dryja T.P. Ocular findings in patients with autosomal dominant retinitis pigmentosa and a rhodopsin gene defect (Pro-23-His). Arch. Ophthalmol. 1991, 109:92-101.
    • (1991) Arch. Ophthalmol. , vol.109 , pp. 92-101
    • Berson, E.L.1    Rosner, B.2    Sandberg, M.A.3    Dryja, T.P.4
  • 4
    • 84856220547 scopus 로고    scopus 로고
    • Expression and localization of the cannabinoid receptor type 1 and the enzyme fatty acid amide hydrolase in the retina of vervet monkeys
    • Bouskila J., Burke M.W., Zabouri N., Casanova C., Ptito M., Bouchard J.F. Expression and localization of the cannabinoid receptor type 1 and the enzyme fatty acid amide hydrolase in the retina of vervet monkeys. Neuroscience 2012, 202:117-130.
    • (2012) Neuroscience , vol.202 , pp. 117-130
    • Bouskila, J.1    Burke, M.W.2    Zabouri, N.3    Casanova, C.4    Ptito, M.5    Bouchard, J.F.6
  • 5
    • 84878627548 scopus 로고    scopus 로고
    • Muller cells express the cannabinoid CB2 receptor in the vervet monkey retina
    • Bouskila J., Javadi P., Casanova C., Ptito M., Bouchard J.F. Muller cells express the cannabinoid CB2 receptor in the vervet monkey retina. J.Comp. Neurol. 2013, 521:2399-2415.
    • (2013) J.Comp. Neurol. , vol.521 , pp. 2399-2415
    • Bouskila, J.1    Javadi, P.2    Casanova, C.3    Ptito, M.4    Bouchard, J.F.5
  • 6
    • 0032533962 scopus 로고    scopus 로고
    • Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse
    • Cayouette M., Behn D., Sendtner M., Lachapelle P., Gravel C. Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse. J.Neurosci. 1998, 18:9282-9293.
    • (1998) J.Neurosci. , vol.18 , pp. 9282-9293
    • Cayouette, M.1    Behn, D.2    Sendtner, M.3    Lachapelle, P.4    Gravel, C.5
  • 7
    • 0033428112 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations
    • Cayouette M., Smith S.B., Becerra S.P., Gravel C. Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations. Neurobiol. Dis. 1999, 6:523-532.
    • (1999) Neurobiol. Dis. , vol.6 , pp. 523-532
    • Cayouette, M.1    Smith, S.B.2    Becerra, S.P.3    Gravel, C.4
  • 9
    • 0032925488 scopus 로고    scopus 로고
    • Repeated injections of a ciliary neurotrophic factor analogue leading to long-term photoreceptor survival in hereditary retinal degeneration
    • Chong N.H., Alexander R.A., Waters L., Barnett K.C., Bird A.C., Luthert P.J. Repeated injections of a ciliary neurotrophic factor analogue leading to long-term photoreceptor survival in hereditary retinal degeneration. Investig. Ophthalmol. Vis. Sci. 1999, 40:1298-1305.
    • (1999) Investig. Ophthalmol. Vis. Sci. , vol.40 , pp. 1298-1305
    • Chong, N.H.1    Alexander, R.A.2    Waters, L.3    Barnett, K.C.4    Bird, A.C.5    Luthert, P.J.6
  • 10
    • 34248171269 scopus 로고    scopus 로고
    • Neuroprotective and intraocular pressure-lowering effects of (-)Delta9-tetrahydrocannabinol in a rat model of glaucoma
    • Crandall J., Matragoon S., Khalifa Y.M., Borlongan C., Tsai N.T., Caldwell R.B., Liou G.I. Neuroprotective and intraocular pressure-lowering effects of (-)Delta9-tetrahydrocannabinol in a rat model of glaucoma. Ophthalmic Res. 2007, 39:69-75.
    • (2007) Ophthalmic Res. , vol.39 , pp. 69-75
    • Crandall, J.1    Matragoon, S.2    Khalifa, Y.M.3    Borlongan, C.4    Tsai, N.T.5    Caldwell, R.B.6    Liou, G.I.7
  • 11
    • 3242704172 scopus 로고    scopus 로고
    • Regressive and reactive changes in the connectivity patterns of rod and cone pathways of P23H transgenic rat retina
    • Cuenca N., Pinilla I., Sauve Y., Lu B., Wang S., Lund R.D. Regressive and reactive changes in the connectivity patterns of rod and cone pathways of P23H transgenic rat retina. Neuroscience 2004, 127:301-317.
    • (2004) Neuroscience , vol.127 , pp. 301-317
    • Cuenca, N.1    Pinilla, I.2    Sauve, Y.3    Lu, B.4    Wang, S.5    Lund, R.D.6
  • 12
    • 34447632664 scopus 로고    scopus 로고
    • The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells
    • Dagon Y., Avraham Y., Link G., Zolotarev O., Mechoulam R., Berry E.M. The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells. Neurobiol. Dis. 2007, 27:174-181.
    • (2007) Neurobiol. Dis. , vol.27 , pp. 174-181
    • Dagon, Y.1    Avraham, Y.2    Link, G.3    Zolotarev, O.4    Mechoulam, R.5    Berry, E.M.6
  • 13
    • 18844377530 scopus 로고    scopus 로고
    • Apoptosis: a potential therapeutic target for retinal degenerations
    • Doonan F., Cotter T.G. Apoptosis: a potential therapeutic target for retinal degenerations. Curr. Neurovasc. Res. 2004, 1:41-53.
    • (2004) Curr. Neurovasc. Res. , vol.1 , pp. 41-53
    • Doonan, F.1    Cotter, T.G.2
  • 14
    • 0033823792 scopus 로고    scopus 로고
    • Novel rhodopsin mutations Gly114Val and Gln184Pro in dominant retinitis pigmentosa
    • Dryja T.P., McEvoy J.A., McGee T.L., Berson E.L. Novel rhodopsin mutations Gly114Val and Gln184Pro in dominant retinitis pigmentosa. Investig. Ophthalmol. Vis. Sci. 2000, 41:3124-3127.
    • (2000) Investig. Ophthalmol. Vis. Sci. , vol.41 , pp. 3124-3127
    • Dryja, T.P.1    McEvoy, J.A.2    McGee, T.L.3    Berson, E.L.4
  • 18
    • 0141884059 scopus 로고    scopus 로고
    • Biphasic modulation of voltage-dependent currents of retinal cones by cannabinoid CB1 receptor agonist WIN 55212-2
    • Fan S.F., Yazulla S. Biphasic modulation of voltage-dependent currents of retinal cones by cannabinoid CB1 receptor agonist WIN 55212-2. Vis. Neurosci. 2003, 20:177-188.
    • (2003) Vis. Neurosci. , vol.20 , pp. 177-188
    • Fan, S.F.1    Yazulla, S.2
  • 25
    • 33846401540 scopus 로고    scopus 로고
    • Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties
    • Garcia-Arencibia M., Gonzalez S., de Lago E., Ramos J.A., Mechoulam R., Fernandez-Ruiz J. Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties. Brain Res. 2007, 1134:162-170.
    • (2007) Brain Res. , vol.1134 , pp. 162-170
    • Garcia-Arencibia, M.1    Gonzalez, S.2    de Lago, E.3    Ramos, J.A.4    Mechoulam, R.5    Fernandez-Ruiz, J.6
  • 28
    • 0034980919 scopus 로고    scopus 로고
    • Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18
    • Green E.S., Rendahl K.G., Zhou S., Ladner M., Coyne M., Srivastava R., Manning W.C., Flannery J.G. Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18. Mol. Ther. 2001, 3:507-515.
    • (2001) Mol. Ther. , vol.3 , pp. 507-515
    • Green, E.S.1    Rendahl, K.G.2    Zhou, S.3    Ladner, M.4    Coyne, M.5    Srivastava, R.6    Manning, W.C.7    Flannery, J.G.8
  • 29
    • 0032493197 scopus 로고    scopus 로고
    • Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants
    • Hampson A.J., Grimaldi M., Axelrod J., Wink D. Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:8268-8273.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 8268-8273
    • Hampson, A.J.1    Grimaldi, M.2    Axelrod, J.3    Wink, D.4
  • 32
    • 0037072934 scopus 로고    scopus 로고
    • Arhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system
    • Illing M.E., Rajan R.S., Bence N.F., Kopito R.R. Arhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system. J.Biol. Chem. 2002, 277:34150-34160.
    • (2002) J.Biol. Chem. , vol.277 , pp. 34150-34160
    • Illing, M.E.1    Rajan, R.S.2    Bence, N.F.3    Kopito, R.R.4
  • 33
    • 23144432156 scopus 로고    scopus 로고
    • Retinal remodeling during retinal degeneration
    • Jones B.W., Marc R.E. Retinal remodeling during retinal degeneration. Exp. Eye Res. 2005, 81:123-137.
    • (2005) Exp. Eye Res. , vol.81 , pp. 123-137
    • Jones, B.W.1    Marc, R.E.2
  • 34
    • 0028287273 scopus 로고
    • Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa
    • Kaushal S., Khorana H.G. Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. Biochemistry 1994, 33:6121-6128.
    • (1994) Biochemistry , vol.33 , pp. 6121-6128
    • Kaushal, S.1    Khorana, H.G.2
  • 35
    • 1842633560 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity
    • Khaspekov L.G., Brenz Verca M.S., Frumkina L.E., Hermann H., Marsicano G., Lutz B. Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity. Eur. J. Neurosci. 2004, 19:1691-1698.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1691-1698
    • Khaspekov, L.G.1    Brenz Verca, M.S.2    Frumkina, L.E.3    Hermann, H.4    Marsicano, G.5    Lutz, B.6
  • 36
    • 77649238609 scopus 로고    scopus 로고
    • Late histological and functional changes in the P23H rat retina after photoreceptor loss
    • Kolomiets B., Dubus E., Simonutti M., Rosolen S., Sahel J.A., Picaud S. Late histological and functional changes in the P23H rat retina after photoreceptor loss. Neurobiol. Dis. 2010, 38:47-58.
    • (2010) Neurobiol. Dis. , vol.38 , pp. 47-58
    • Kolomiets, B.1    Dubus, E.2    Simonutti, M.3    Rosolen, S.4    Sahel, J.A.5    Picaud, S.6
  • 38
    • 33749648816 scopus 로고    scopus 로고
    • Cannabinoid receptor-mediated inhibition of calcium signaling in rat retinal ganglion cells
    • Lalonde M.R., Jollimore C.A., Stevens K., Barnes S., Kelly M.E. Cannabinoid receptor-mediated inhibition of calcium signaling in rat retinal ganglion cells. Mol. Vis. 2006, 12:1160-1166.
    • (2006) Mol. Vis. , vol.12 , pp. 1160-1166
    • Lalonde, M.R.1    Jollimore, C.A.2    Stevens, K.3    Barnes, S.4    Kelly, M.E.5
  • 39
    • 79951595560 scopus 로고    scopus 로고
    • Circadian dysfunction in P23H rhodopsin transgenic rats: effects of exogenous melatonin
    • Lax P., Otalora B.B., Esquiva G., Rol Mde L., Madrid J.A., Cuenca N. Circadian dysfunction in P23H rhodopsin transgenic rats: effects of exogenous melatonin. J.Pineal Res. 2011, 50:183-191.
    • (2011) J.Pineal Res. , vol.50 , pp. 183-191
    • Lax, P.1    Otalora, B.B.2    Esquiva, G.3    Rol Mde, L.4    Madrid, J.A.5    Cuenca, N.6
  • 40
    • 0041621495 scopus 로고    scopus 로고
    • Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210
    • Leker R.R., Gai N., Mechoulam R., Ovadia H. Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210. Stroke 2003, 34:2000-2006.
    • (2003) Stroke , vol.34 , pp. 2000-2006
    • Leker, R.R.1    Gai, N.2    Mechoulam, R.3    Ovadia, H.4
  • 44
    • 79952229520 scopus 로고    scopus 로고
    • Distribution of CB2 cannabinoid receptor in adult rat retina
    • Lopez E.M., Tagliaferro P., Onaivi E.S., Lopez-Costa J.J. Distribution of CB2 cannabinoid receptor in adult rat retina. Synapse 2011, 65:388-392.
    • (2011) Synapse , vol.65 , pp. 388-392
    • Lopez, E.M.1    Tagliaferro, P.2    Onaivi, E.S.3    Lopez-Costa, J.J.4
  • 46
    • 0742304250 scopus 로고    scopus 로고
    • Retinal remodeling in inherited photoreceptor degenerations
    • Marc R.E., Jones B.W. Retinal remodeling in inherited photoreceptor degenerations. Mol. Neurobiol. 2003, 28:139-147.
    • (2003) Mol. Neurobiol. , vol.28 , pp. 139-147
    • Marc, R.E.1    Jones, B.W.2
  • 48
    • 0036488182 scopus 로고    scopus 로고
    • Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1
    • Marsicano G., Moosmann B., Hermann H., Lutz B., Behl C. Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J.Neurochem. 2002, 80:448-456.
    • (2002) J.Neurochem. , vol.80 , pp. 448-456
    • Marsicano, G.1    Moosmann, B.2    Hermann, H.3    Lutz, B.4    Behl, C.5
  • 50
    • 0035664438 scopus 로고    scopus 로고
    • Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa
    • McGee Sanftner L.H., Abel H., Hauswirth W.W., Flannery J.G. Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa. Mol. Ther. 2001, 4:622-629.
    • (2001) Mol. Ther. , vol.4 , pp. 622-629
    • McGee Sanftner, L.H.1    Abel, H.2    Hauswirth, W.W.3    Flannery, J.G.4
  • 52
    • 84856162549 scopus 로고    scopus 로고
    • Cannabinoids modulate spontaneous synaptic activity in retinal ganglion cells
    • Middleton T.P., Protti D.A. Cannabinoids modulate spontaneous synaptic activity in retinal ganglion cells. Vis. Neurosci. 2011, 28:393-402.
    • (2011) Vis. Neurosci. , vol.28 , pp. 393-402
    • Middleton, T.P.1    Protti, D.A.2
  • 53
    • 79957911368 scopus 로고    scopus 로고
    • Current concepts in the treatment of retinitis pigmentosa
    • Musarella M.A., Macdonald I.M. Current concepts in the treatment of retinitis pigmentosa. J.Ophthalmol. 2011, 2011:753547.
    • (2011) J.Ophthalmol. , vol.2011 , pp. 753547
    • Musarella, M.A.1    Macdonald, I.M.2
  • 54
    • 0027329873 scopus 로고
    • 2+ influx through the N-methyl-D-aspartate receptor ion channel by the non-psychoactive cannabinoid HU-211
    • 2+ influx through the N-methyl-D-aspartate receptor ion channel by the non-psychoactive cannabinoid HU-211. Brain Res. 1993, 622:79-85.
    • (1993) Brain Res. , vol.622 , pp. 79-85
    • Nadler, V.1    Mechoulam, R.2    Sokolovsky, M.3
  • 56
    • 0037704444 scopus 로고    scopus 로고
    • Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage
    • Okoye G., Zimmer J., Sung J., Gehlbach P., Deering T., Nambu H., Hackett S., Melia M., Esumi N., Zack D.J., Campochiaro P.A. Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage. J.Neurosci. 2003, 23:4164-4172.
    • (2003) J.Neurosci. , vol.23 , pp. 4164-4172
    • Okoye, G.1    Zimmer, J.2    Sung, J.3    Gehlbach, P.4    Deering, T.5    Nambu, H.6    Hackett, S.7    Melia, M.8    Esumi, N.9    Zack, D.J.10    Campochiaro, P.A.11
  • 57
    • 33746796735 scopus 로고    scopus 로고
    • Inhibition of potassium- and ischemia-evoked [3H] D-aspartate release from isolated bovine retina by cannabinoids
    • Opere C.A., Zheng W.D., Zhao M., Lee J.S., Kulkarni K.H., Ohia S.E. Inhibition of potassium- and ischemia-evoked [3H] D-aspartate release from isolated bovine retina by cannabinoids. Curr. Eye Res. 2006, 31:645-653.
    • (2006) Curr. Eye Res. , vol.31 , pp. 645-653
    • Opere, C.A.1    Zheng, W.D.2    Zhao, M.3    Lee, J.S.4    Kulkarni, K.H.5    Ohia, S.E.6
  • 58
    • 0034953340 scopus 로고    scopus 로고
    • Hu 210: a potent tool for investigations of the cannabinoid system
    • Ottani A., Giuliani D. Hu 210: a potent tool for investigations of the cannabinoid system. CNS Drug. Rev. 2001, 7:131-145.
    • (2001) CNS Drug. Rev. , vol.7 , pp. 131-145
    • Ottani, A.1    Giuliani, D.2
  • 59
    • 57649213243 scopus 로고    scopus 로고
    • Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death
    • Pellegrini-Giampietro D.E., Mannaioni G., Bagetta G. Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death. FEBS J. 2009, 276:2-12.
    • (2009) FEBS J. , vol.276 , pp. 2-12
    • Pellegrini-Giampietro, D.E.1    Mannaioni, G.2    Bagetta, G.3
  • 60
    • 0032802188 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid receptor ligands
    • Pertwee R.G. Pharmacology of cannabinoid receptor ligands. Curr. Med. Chem. 1999, 6:635-664.
    • (1999) Curr. Med. Chem. , vol.6 , pp. 635-664
    • Pertwee, R.G.1
  • 61
    • 84868128338 scopus 로고    scopus 로고
    • Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities
    • Pertwee R.G. Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities. Philos. Trans. R. Soc. Lond B Biol. Sci. 2012, 367:3353-3363.
    • (2012) Philos. Trans. R. Soc. Lond B Biol. Sci. , vol.367 , pp. 3353-3363
    • Pertwee, R.G.1
  • 62
    • 84875653203 scopus 로고    scopus 로고
    • Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat
    • Pinar-Sueiro S., Zorrilla Hurtado J.A., Veiga-Crespo P., Sharma S.C., Vecino E. Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat. Exp. Eye Res. 2013, 110:55-58.
    • (2013) Exp. Eye Res. , vol.110 , pp. 55-58
    • Pinar-Sueiro, S.1    Zorrilla Hurtado, J.A.2    Veiga-Crespo, P.3    Sharma, S.C.4    Vecino, E.5
  • 63
    • 34547880446 scopus 로고    scopus 로고
    • Preservation of outer retina and its synaptic connectivity following subretinal injections of human RPE cells in the Royal College of Surgeons rat
    • Pinilla I., Cuenca N., Sauve Y., Wang S., Lund R.D. Preservation of outer retina and its synaptic connectivity following subretinal injections of human RPE cells in the Royal College of Surgeons rat. Exp. Eye Res. 2007, 85:381-392.
    • (2007) Exp. Eye Res. , vol.85 , pp. 381-392
    • Pinilla, I.1    Cuenca, N.2    Sauve, Y.3    Wang, S.4    Lund, R.D.5
  • 64
    • 19444380510 scopus 로고    scopus 로고
    • Enhanced cone dysfunction in rats homozygous for the P23H rhodopsin mutation
    • Pinilla I., Lund R.D., Sauve Y. Enhanced cone dysfunction in rats homozygous for the P23H rhodopsin mutation. Neurosci. Lett. 2005, 382:16-21.
    • (2005) Neurosci. Lett. , vol.382 , pp. 16-21
    • Pinilla, I.1    Lund, R.D.2    Sauve, Y.3
  • 65
    • 77956228507 scopus 로고    scopus 로고
    • Endocannabinoid signaling in neurotoxicity and neuroprotection
    • Pope C., Mechoulam R., Parsons L. Endocannabinoid signaling in neurotoxicity and neuroprotection. Neurotoxicology 2010, 31:562-571.
    • (2010) Neurotoxicology , vol.31 , pp. 562-571
    • Pope, C.1    Mechoulam, R.2    Parsons, L.3
  • 66
    • 14244264502 scopus 로고    scopus 로고
    • Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation
    • Ramirez B.G., Blazquez C., Gomez del Pulgar T., Guzman M., de Ceballos M.L. Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation. J.Neurosci. 2005, 25:1904-1913.
    • (2005) J.Neurosci. , vol.25 , pp. 1904-1913
    • Ramirez, B.G.1    Blazquez, C.2    Gomez del Pulgar, T.3    Guzman, M.4    de Ceballos, M.L.5
  • 68
    • 0036351963 scopus 로고    scopus 로고
    • Cell death in retinitis pigmentosa: gap junctions and the 'bystander' effect
    • Ripps H. Cell death in retinitis pigmentosa: gap junctions and the 'bystander' effect. Exp. Eye Res. 2002, 74:327-336.
    • (2002) Exp. Eye Res. , vol.74 , pp. 327-336
    • Ripps, H.1
  • 69
    • 80051904574 scopus 로고    scopus 로고
    • Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults
    • Rubio M., Villain H., Docagne F., Roussel B.D., Ramos J.A., Vivien D., Fernandez-Ruiz J., Ali C. Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. PLoS One 2011, 6:e23690.
    • (2011) PLoS One , vol.6
    • Rubio, M.1    Villain, H.2    Docagne, F.3    Roussel, B.D.4    Ramos, J.A.5    Vivien, D.6    Fernandez-Ruiz, J.7    Ali, C.8
  • 70
    • 0027250138 scopus 로고
    • Anonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat
    • Shohami E., Novikov M., Mechoulam R. Anonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat. J.Neurotrauma 1993, 10:109-119.
    • (1993) J.Neurotrauma , vol.10 , pp. 109-119
    • Shohami, E.1    Novikov, M.2    Mechoulam, R.3
  • 71
    • 77955343579 scopus 로고    scopus 로고
    • TgAAG76, an adeno-associated virus delivered gene therapy for the potential treatment of vision loss caused by RPE65 gene abnormalities
    • Stieger K. tgAAG76, an adeno-associated virus delivered gene therapy for the potential treatment of vision loss caused by RPE65 gene abnormalities. Curr. Opin. Mol. Ther. 2010, 12:471-477.
    • (2010) Curr. Opin. Mol. Ther. , vol.12 , pp. 471-477
    • Stieger, K.1
  • 73
    • 0033405204 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system
    • Straiker A., Stella N., Piomelli D., Mackie K., Karten H.J., Maguire G. Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:14565-14570.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 14565-14570
    • Straiker, A.1    Stella, N.2    Piomelli, D.3    Mackie, K.4    Karten, H.J.5    Maguire, G.6
  • 74
    • 0038217007 scopus 로고    scopus 로고
    • Cannabinoid receptor activation differentially modulates ion channels in photoreceptors of the tiger salamander
    • Straiker A., Sullivan J.M. Cannabinoid receptor activation differentially modulates ion channels in photoreceptors of the tiger salamander. J.Neurophysiol. 2003, 89:2647-2654.
    • (2003) J.Neurophysiol. , vol.89 , pp. 2647-2654
    • Straiker, A.1    Sullivan, J.M.2
  • 76
    • 24644450190 scopus 로고    scopus 로고
    • Cannabinoid receptors and their role in neuroprotection
    • van der Stelt M., Di Marzo V. Cannabinoid receptors and their role in neuroprotection. Neuromolecular Med. 2005, 7:37-50.
    • (2005) Neuromolecular Med. , vol.7 , pp. 37-50
    • van der Stelt, M.1    Di Marzo, V.2
  • 77
    • 78149471067 scopus 로고    scopus 로고
    • The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats
    • Walsh S., Gorman A.M., Finn D.P., Dowd E. The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats. Brain Res. 2010, 1363:40-48.
    • (2010) Brain Res. , vol.1363 , pp. 40-48
    • Walsh, S.1    Gorman, A.M.2    Finn, D.P.3    Dowd, E.4
  • 78
    • 53449096390 scopus 로고    scopus 로고
    • Endocannabinoids in the retina: from marijuana to neuroprotection
    • Yazulla S. Endocannabinoids in the retina: from marijuana to neuroprotection. Prog. Retin Eye Res. 2008, 27:501-526.
    • (2008) Prog. Retin Eye Res. , vol.27 , pp. 501-526
    • Yazulla, S.1
  • 79
    • 0033530858 scopus 로고    scopus 로고
    • Immunocytochemical localization of cannabinoid CB1 receptor and fatty acid amide hydrolase in rat retina
    • Yazulla S., Studholme K.M., McIntosh H.H., Deutsch D.G. Immunocytochemical localization of cannabinoid CB1 receptor and fatty acid amide hydrolase in rat retina. J.Comp. Neurol. 1999, 415:80-90.
    • (1999) J.Comp. Neurol. , vol.415 , pp. 80-90
    • Yazulla, S.1    Studholme, K.M.2    McIntosh, H.H.3    Deutsch, D.G.4
  • 80
    • 0033935228 scopus 로고    scopus 로고
    • Cannabinoid receptors on goldfish retinal bipolar cells: electron-microscope immunocytochemistry and whole-cell recordings
    • Yazulla S., Studholme K.M., McIntosh H.H., Fan S.F. Cannabinoid receptors on goldfish retinal bipolar cells: electron-microscope immunocytochemistry and whole-cell recordings. Vis. Neurosci. 2000, 17:391-401.
    • (2000) Vis. Neurosci. , vol.17 , pp. 391-401
    • Yazulla, S.1    Studholme, K.M.2    McIntosh, H.H.3    Fan, S.F.4
  • 81
    • 84873082457 scopus 로고    scopus 로고
    • The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects
    • Zogopoulos P., Vasileiou I., Patsouris E., Theocharis S. The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects. J.Appl. Toxicol. 2013, 33:246-264.
    • (2013) J.Appl. Toxicol. , vol.33 , pp. 246-264
    • Zogopoulos, P.1    Vasileiou, I.2    Patsouris, E.3    Theocharis, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.