Circadian dysfunction in P23H rhodopsin transgenic rats: Effects of exogenous melatonin

Journal of Pineal Research

Volumn 50, Issue 2, 2011, Pages 183-191

  Lax, Pedro ^a   Otalora, Beatriz Baño ^b   Esquiva, Gema ^a   Rol, María De Los Ángeles ^b   Madrid, Juan Antonio ^b   Cuenca, Nicolás ^a  

^a UNIVERSITY OF ALICANTE   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

Author keywords

chronodisruption; core temperature rhythm; electroretinogram; melatonin; P23H; retinitis pigmentosa

Indexed keywords

M 5250; MELATONIN; RHODOPSIN; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B WAVE; BODY TEMPERATURE; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM SLEEP DISORDER; CONTROLLED STUDY; DRUG EFFECT; ELECTRORETINOGRAPHY; HISTOPATHOLOGY; MALE; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PHOTORECEPTOR; RAT; RETINA DEGENERATION; TRANSGENIC RAT; TREATMENT RESPONSE; VISION; WILD TYPE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIOXIDANTS; BODY TEMPERATURE; CIRCADIAN RHYTHM; ELECTRORETINOGRAPHY; MALE; MELATONIN; RATS; RATS, SPRAGUE-DAWLEY; RETINAL DEGENERATION; RHODOPSIN;

EID: 79951595560     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00827.x     Document Type: Article

References (57)

1. Reppert SM, Weaver DR,. Coordination of circadian timing in mammals. Nature 2002; 418: 935-941. (Pubitemid 34976023)
2. Czeisler CA, Kronauer RE, Allan JS, et al. Bright light induction of strong (type 0) resetting of the human circadian pacemaker. Science 1989; 244: 1328-1333. (Pubitemid 19170503)
3. Czeisler CA, Allan JS, Strogatz SH, et al. Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle. Science 1986; 233: 667-671. (Pubitemid 16011618)
4. Gooley JJ, Lu J, Chou TC, et al. Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci 2001; 4: 1165. (Pubitemid 33135616)
5. Hattar S, Liao HW, Takao M, et al. Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science 2002; 295: 1065-1070. (Pubitemid 34132235)
6. Hattar S, Lucas RJ, Mrosovsky N, et al. Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature 2003; 424: 76-81. (Pubitemid 36834844)
7. Rajaratnam SM, Arendt J,. Health in a 24-h society. Lancet 2001; 358: 999-1005. (Pubitemid 32913531)
8. Smith L, Folkard S, Poole CJ,. Increased injuries on night shift. Lancet 1994; 344: 1137-1139. (Pubitemid 24317636)
9. Costa G,. The impact of shift and night work on health. Appl Ergon 1996; 27: 9-16. (Pubitemid 26034384)
10. Turek FW, Penev P, Zhang Y, et al. Effects of age on the circadian system. Neurosci Biobehav Rev 1995; 19: 53-58.
11. Zhang Y, Kornhauser JM, Zee PC, et al. Effects of aging on light-induced phase-shifting of circadian behavioral rhythms, fos expression and CREB phosphorylation in the hamster suprachiasmatic nucleus. Neuroscience 1996; 70: 951-961. (Pubitemid 26014859)
12. Mormont MC, Levi F,. Circadian-system alterations during cancer processes: a review. Int J Cancer 1997; 70: 241-247. (Pubitemid 27107423)
13. Drouyer E, Dkhissi-Benyahya O, Chiquet C, et al. Glaucoma alters the circadian timing system. PLoS ONE 2008; 3: e3931.
14. Jean-Louis G, Zizi F, Lazzaro DR, et al. Circadian rhythm dysfunction in glaucoma: a hypothesis. J Circadian Rhythms 2008; 6: 1.
15. Skene DJ, Arendt J,. Circadian rhythm sleep disorders in the blind and their treatment with melatonin. Sleep Med 2007; 8: 651-655. (Pubitemid 47181208)
16. Lockley SW, Skene DJ, James K, et al. Melatonin administration can entrain the free-running circadian system of blind subjects. J Endocrinol 2000; 164: R1-R6. (Pubitemid 30044335)
17. Hack LM, Lockley SW, Arendt J, et al. The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects. J Biol Rhythms 2003; 18: 420-429. (Pubitemid 37204464)
18. Skene DJ, Lockley SW, Arendt J,. Melatonin in circadian sleep disorders in the blind. Biol Signals Recept 1999; 8: 90-95. (Pubitemid 29132389)
19. Dryja TP, Mcgee TL, Reichel E, et al. A point mutation of the rhodopsin gene in one form of retinitis pigmentosa. Nature 1990; 343: 364-366.
20. Dryja TP, Mcevoy JA, Mcgee TL, et al. Novel rhodopsin mutations Gly114Val and Gln184Pro in dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci 2000; 41: 3124-3127.
21. Berson EL, Rosner B, Sandberg MA, et al. Ocular findings in patients with autosomal dominant retinitis pigmentosa and a rhodopsin gene defect (Pro-23-His). Arch Ophthalmol 1991; 109: 92-101.
22. Machida S, Kondo M, Jamison JA, et al. P23H rhodopsin transgenic rat: correlation of retinal function with histopathology. Invest Ophthalmol Vis Sci 2000; 41: 3200-3209.
23. Cuenca N, Pinilla I, Sauve Y, et al. Regressive and reactive changes in the connectivity patterns of rod and cone pathways of P23H transgenic rat retina. Neuroscience 2004; 127: 301-317. (Pubitemid 38950646)
24. Pinilla I, Lund RD, Sauve Y,. Enhanced cone dysfunction in rats homozygous for the P23H rhodopsin mutation. Neurosci Lett 2005; 382: 16-21. (Pubitemid 40725858)
25. Marc RE, Jones BW, Watt CB, et al. Neural remodeling in retinal degeneration. Prog Retin Eye Res 2003; 22: 607-655. (Pubitemid 36936804)
26. Puthussery T, Taylor WR,. Functional changes in inner retinal neurons in animal models of photoreceptor degeneration. Adv Exp Med Biol 2010; 664: 525-532.
27. Jones BW, Watt CB, Frederick JM, et al. Retinal remodeling triggered by photoreceptor degenerations. J Comp Neurol 2003; 464: 1-16. (Pubitemid 36899033)
28. Kolomiets B, Dubus E, Simonutti M, et al. Late histological and functional changes in the P23H rat retina after photoreceptor loss. Neurobiol Dis 2010; 38: 47-58.
29. Congdon N, Ocolmain B, Klaver CC, et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol 2004; 122: 477-485. (Pubitemid 38456282)
30. Yamada M, Hiratsuka Y, Roberts CB, et al. Prevalence of visual impairment in the adult Japanese population by cause and severity and future projections. Ophthalmic Epidemiol 2010; 17: 50-57.
31. Otalora BB, Madrid JA, Alvarez N, et al. Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice. J Pineal Res 2008; 44: 307-315. (Pubitemid 351392944)
32. Vivanco P, Ortiz V, Rol MA, et al. Looking for the keys to diurnality downstream from the circadian clock: role of melatonin in a dual-phasing rodent, Octodon degus. J Pineal Res 2007; 42: 280-290. (Pubitemid 46365066)
33. Ortiz-Tudela E, Martinez-Nicolas A, Campos M, et al. A new integrated variable based on thermometry, actimetry and body position (TAP) to evaluate circadian system status in humans. PLoS Comput Biol 2010; 6.
34. Gordo MA, Recio J, Sanchez-Barcelo EJ,. Decreased sleep quality in patients suffering from retinitis pigmentosa. J Sleep Res 2001; 10: 159-164. (Pubitemid 32525686)
35. Ionescu D, Driver HS, Heon E, et al. Sleep and daytime sleepiness in retinitis pigmentosa patients. J Sleep Res 2001; 10: 329-335. (Pubitemid 34014780)
36. Mrosovsky N, Thompson S,. Negative and positive masking responses to light in retinal degenerate slow (rds/rds) mice during aging. Vision Res 2008; 48: 1270-1273.
37. Banas I, Buntner B, Niebroj T, et al. [Levels of melatonin in serum of patients with retinitis pigmentosa]. Klin Oczna 1995; 97: 321-323. (Pubitemid 26109593)
38. Turner PL, Mainster MA,. Circadian photoreception: ageing and the eyes important role in systemic health. Br J Ophthalmol 2008; 92: 1439-1444.
39. Belforte NA, Moreno MC, De Zavalia N, et al. Melatonin: a novel neuroprotectant for the treatment of glaucoma. J Pineal Res 2010; 48: 353-364.
40. Tan DX, Chen LD, Poeggeler B, et al. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr J 1993; 1: 57-60.
41. Liang FQ, Green L, Wang C, et al. Melatonin protects human retinal pigment epithelial (RPE) cells against oxidative stress. Exp Eye Res 2004; 78: 1069-1075. (Pubitemid 38510344)
42. Paradies G, Petrosillo G, Paradies V, et al. Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res 2010; 48: 297-310.
43. Jou MJ, Peng TI, Hsu LF, et al. Visualization of melatonins multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes. J Pineal Res 2010; 48: 20-38.
44. Lundmark PO, Pandi-Perumal SR, Srinivasan V, et al. Role of melatonin in the eye and ocular dysfunctions. Vis Neurosci 2006; 23: 853-862. (Pubitemid 46456691)
45. Siu AW, Maldonado M, Sanchez-Hidalgo M, et al. Protective effects of melatonin in experimental free radical-related ocular diseases. J Pineal Res 2006; 40: 101-109.
46. Siu AW, Reiter RJ, To CH,. The efficacy of vitamin E and melatonin as antioxidants against lipid peroxidation in rat retinal homogenates. J Pineal Res 1998; 24: 239-244. (Pubitemid 28206445)
47. Lundmark PO, Pandi-Perumal SR, Srinivasan V, et al. Melatonin in the eye: implications for glaucoma. Exp Eye Res 2007; 84: 1021-1030. (Pubitemid 46783812)
48. Rosenstein RE, Pandi-Perumal SR, Srinivasan V, et al. Melatonin as a therapeutic tool in ophthalmology: implications for glaucoma and uveitis. J Pineal Res 2010; 49: 1-13.
49. Sande PH, Fernandez DC, Aldana Marcos HJ, et al. Therapeutic effect of melatonin in experimental uveitis. Am J Pathol 2008; 173: 1702-1713.
50. Yi C, Pan X, Yan H, et al. Effects of melatonin in age-related macular degeneration. Ann N Y Acad Sci 2005; 1057: 384-392. (Pubitemid 43211648)
51. Abe M, Reiter RJ, Orhii PB, et al. Inhibitory effect of melatonin on cataract formation in newborn rats: evidence for an antioxidative role for melatonin. J Pineal Res 1994; 17: 94-100.
52. Li ZR, Reiter RJ, Fujimori O, et al. Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: preventive actions of melatonin. J Pineal Res 1997; 22: 117-123. (Pubitemid 127731747)
53. Yagci R, Aydin B, Erdurmus M, et al. Use of melatonin to prevent selenite-induced cataract formation in rat eyes. Curr Eye Res 2006; 31: 845-850. (Pubitemid 44581307)
54. Liang FQ, Aleman TS, Zaixinyang, et al. Melatonin delays photoreceptor degeneration in the rds/rds mouse. Neuroreport 2001; 12: 1011-1014. (Pubitemid 32281465)
55. Doonan F, Donovan M, Cotter TG,. Activation of multiple pathways during photoreceptor apoptosis in the rd mouse. Invest Ophthalmol Vis Sci 2005; 46: 3530-3538. (Pubitemid 44264653)
56. Wiechmann AF, Chignell CF, Roberts JE,. Influence of dietary melatonin on photoreceptor survival in the rat retina: an ocular toxicity study. Exp Eye Res 2008; 86: 241-250.
57. Yuan J,. Effects of drinking pattern on the peak/trough blood concentrations in drinking water studies. Food Chem Toxicol 1995; 33: 565-571.