Reduced levels of mitochondrial complex i subunit NDUFB8 and linked complex i + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 39, Issue 2, 2014, Pages 347-355

  Francis, Beverly M ^a,b   Yang, Jimao ^a   Song, Byung Jun ^c   Gupta, Saurabh ^d   Maj, Mary ^d   Bazinet, Richard P ^c   Robinson, Brian ^d   Mount, Howard T J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Alzheimer's disease; amyloid; ATP; cardiolipin; creatine; electron transport chain; NDUFB8

Indexed keywords

CARDIOLIPIN; CREATINE; CYTOCHROME C OXIDASE; FATTY ACID; NDUFB8 ENZYME; OXOGLUTARATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME SUBUNIT; FEMALE; HIPPOCAMPUS; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ALZHEIMER'S DISEASE; AMYLOID; ATP; CARDIOLIPIN; CREATINE; ELECTRON TRANSPORT CHAIN; NDUFB8;

ADENOSINE TRIPHOSPHATE; AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CARDIOLIPINS; CEREBRAL CORTEX; CREATINE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX III; ELECTRON TRANSPORT COMPLEX IV; HIPPOCAMPUS; HUMANS; KETOGLUTARATE DEHYDROGENASE COMPLEX; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PYRUVATE DEHYDROGENASE COMPLEX;

EID: 84893981123     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-131499     Document Type: Article

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