Object recognition memory and BDNF expression are reduced in young TgCRND8 mice

Neurobiology of Aging

Volumn 33, Issue 3, 2012, Pages 555-563

  Francis, Beverly M ^a,b   Kim, John ^a,b   Barakat, Meredith E ^a,b   Fraenkl, Stephan ^b,c   Yücel, Yeni H ^b,c   Peng, Shiyong ^d   Michalski, Bernadeta ^d   Fahnestock, Margaret ^d   McLaurin, JoAnne ^a,b   Mount, Howard T J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

Alzheimer's disease; Amyloid precursor protein (APP); Brain derived neurotrophic factor (BDNF); Entorhinal cortex; Hippocampus; Morris water maze; Object recognition memory; Optokinetic responses; Real Time RT PCR; Spatial memory; TgCRND8 mice

Indexed keywords

AMYLOID; BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; MAZE TEST; MORRIS WATER MAZE TASK; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; OBJECT RECOGNITION TASK; PRIORITY JOURNAL; SHORT TERM MEMORY; SPATIAL MEMORY; TASK PERFORMANCE; VISION;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CRICETINAE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FRONTAL LOBE; HIPPOCAMPUS; HUMANS; MEMORY DISORDERS; MESOCRICETUS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; RECOGNITION (PSYCHOLOGY); RNA, MESSENGER;

EID: 84883841879     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.04.003     Document Type: Article

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