Identification of 167 polymorphisms in 88 genes from candidate neurodegeneration pathways

Gene

Volumn 238, Issue 2, 1999, Pages 315-324

  Emahazion, Tesfai ^a,b   Jobs, Magnus ^a   Howell, W Mathias ^a   Siegfried, Marianne ^a   Wyöni, Per Ivan ^b   Prince, Jonathan A ^a   Brookes, Anthony J ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Candidate genes; Discovery; Neurodegeneration; Single nucleotide polymorphism

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DNA FRAGMENT;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DNA POLYMORPHISM; DNA SEQUENCE; GENETIC ASSOCIATION; GENETIC PROCEDURES; GENETIC VARIABILITY; HUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

EVOLUTION, MOLECULAR; HUMANS; NEURODEGENERATIVE DISEASES; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 0032847516     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00330-3     Document Type: Article

References (40)

1. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
2. Beal M.F. Mitochondrial dysfunction in neurodegenerative diseases. Biochim. Biophys. Acta. 1366:1998;211-223.
3. Blacker D., Wilcox M.A., Laird N.M., Rodes L., Horvath S.M., Go R.C., Perry R., Watson B., Bassett S.S., McInnis M.G., Albert M.S., Hyman B.T., Tanzi R.E. Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat. Genet. 19:1998;357-360.
4. Boguski M.S., Lowe T.M., Tolstoshev C.M. dbEST - database for 'expressed sequence tags'. Nat. Genet. 4:1993;332-333.
5. Brookes A.J. The essence of SNPs. Gene. 234:1999;177-186.
6. Buetow K.H., Edmonson M.N., Cassidy A.B. Reliable identification of large numbers of candidate SNPs from public EST data. Nat. Genet. 21:1999;323-325.
7. Chakravarti A. It's raining SNPs, hallelujah? Nat. Genet. 19:1998;216-217.
8. Collins F.S. Positional cloning moves from perditional to traditional. Nat. Genet. 9:1995;347-350.
9. Cooper D.N., Smith B.A., Cooke H.J., Niemann S., Schmidtke J. An estimate of unique DNA sequence heterozygosity in the human genome. Hum. Genet. 69:1985;201-205.
10. Cooper D.N., Ball E.V., Krawczak M. The human gene mutation database. Nucleic Acids Res. 26:1998;285-287.
11. Cotman C.W., Whittemore E.R., Watt J.A., Anderson A.J., Loo D.T. Possible role of apoptosis in Alzheimer's disease. Ann. NY Acad. Sci. 747:1994;36-49.
12. Emahazion T., Beskow A., Gyllensten U., Brookes A.J. Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. Cytogenet. Cell Genet. 82:1998;115-119.
13. Engkvist H., Gyllensten U. Rapid DNA purification from Agarose Gels Using 96-Well Format, Centrifuge-Driven Filtration. BioTechniques. 25:1998;346-348.
14. Finch C.E., Tanzi R.E. Genetics and aging. Science. 278:1997;407-411.
15. Gill R.W., Hodgman T.C., Littler C.B., Oxer M.D., Montgomery D.S., Taylor S., Sanseau P. A new dynamic tool to perform assembly of expressed sequence tags (ESTs). Comput. Appl. Biosci. 13:1997;453-457.
16. Goate A., Chartier-Harlin M.C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A, Irving N., James L., et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 349:1991;704-706.
17. Gu Z., Hillier L., Kwok P.Y. Single nucleotide polymorphism hunting in cyberspace. Hum. Mutat. 12:1998;221-225.
18. Howell W.M., Jobs M., Gyllensten U., Brookes A.J. Dynamic allele-specific hybridization. A new method for scoring single nucleotide polymorphisms. Nat. Biotechnol. 17:1999;87-88.
19. Kehoe P., et al. A full genome scan for late onset Alzheimer's disease. Hum. Mol. Genet. 8:1999;237-245.
20. Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., Shimizu N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature. 392:1998;605-6088.
21. Kruglyak L. The use of a genetic map of biallelic markers in linkage studies. Nat. Genet. 17:1997;21-24.
22. Kwok P.Y., Deng Q., Zakeri H., Nickerson D.A. Increasing the information content of STS-based genome maps:identifying polymorphisms in mapped STSs. Genomics. 31:1996;123-126.
23. Lander E.S. The new genomics: global views of biology. Science. 274:1996;536-539.
24. Levy-Lahad E., Wasco W., Poorkaj P., Romano D.M., Oshima J., Pettingell W.H., Yu C.E., Jondro P.D., Schmidt S.D., Wang K. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science. 269:1995;973-977.
25. Li W.H., Sadler L.A. Low nucleotide diversity in man. Genetics. 129:1991;513-523.
26. Ludolph A.C., Riepe M., Ullrich K. Excitotoxicity, energy metabolism and neurodegeneration. J. Inherit. Metab. Dis. 16:1993;716-723.
27. McGeer E.G., McGeer P.L. The importance of inflammatory mechanisms in Alzheimer disease. Exp. Gerontol. 33:1998;371-378.
28. Marshall E. 'Playing chicken' over gene markers. Science. 278:1997;2046-2048.
29. Namekata K., Imagawa M., Terashi A., Ohta S., Oyama F., Ihara Y. Association of transferrin C2 allele with late-onset Alzheimer's disease. Hum. Genet. 101:1997;126-129.
30. Nussbaum R.L., Polymeropoulos M.H. Genetics of Parkinson's disease. Hum. Mol. Genet. 6:1997;1687-1691.
31. Picoult-Newberg L., Ideker T.E., Pohl M.G., Taylor S.L., Donaldson M.A., Nickerson D.A., Boyce-Jacino M. Mining SNPs from EST databases. Genome Res. 9:1999;167-174.
32. Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W.G., Lazzarini A.M., Duvoisin R.C., DiIorio G., Golbe L.I., Nussbaum R.L. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science. 276:1997;2045-2047.
33. Risch N., Mrikangas K. The future of genetic studies of complex human diseases. Science. 273:1996;1516-1517.
34. Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T., et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 376:1995;775-778.
35. Roses A.D. Alzheimer Diseases: A model of gene mutation and susceptibility polymorphisms for complex psychiatric disease. Am. J. Med. Genet. 81:1998;49-57.
36. Sherrington R., Rogaev E.I., Liang Y., Rogaeva E.A., Levesque G., Ikeda M., Chi H., Lin C., Li G., Holman K., et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375:1995;754-760.
37. Strittmatter W.J., Roses A.D. Apolipoprotein E and Alzheimer's disease. Annu. Rev. Neurosci. 19:1996;53-77.
38. Wallace D.C., Brown M.D., Melov S., Graham B., Lott M. Mitochondrial biology, degenerative diseases and aging. Biofactors. 1998:(7):1998;187-190.
39. Wang D.G., et al. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science. 280:1998;1077-1082.
40. Wolfsberg T.G., Landsman D. A comparison of expressed sequence tags (ESTs) to human genomic sequences. Nucleic Acids Res. 25:1997;1626-1632.