Evolution of three human GPCRs for higher expression and stability

Journal of Molecular Biology

Volumn 408, Issue 4, 2011, Pages 599-615

  Dodevski, Igor ^a   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

directed evolution; expression in E. coli; GPCR; protein engineering; stability

Indexed keywords

ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; COMPLEMENTARY DNA; DETERGENT; G PROTEIN COUPLED RECEPTOR; MEMBRANE PROTEIN; NEUROTENSIN RECEPTOR; TACHYKININ RECEPTOR;

ARTICLE; BIOASSAY; ESCHERICHIA COLI; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SOLUBILITY; THERMOSTABILITY; WILD TYPE;

ESCHERICHIA COLI;

EID: 79955021788     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.02.051     Document Type: Article

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