-
1
-
-
59649112109
-
Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation
-
Ahuja S., Hornak V., Yan E.C.Y., Syrett N., Goncalves J.A., Hirshfeld A., Ziliox M., Sakmar T.P., Sheves M., Reeves P.J., Smith S.O., Eilers M. Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation. Nat. Struct. Mol. Biol. 2009, 16:168-175.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 168-175
-
-
Ahuja, S.1
Hornak, V.2
Yan, E.C.Y.3
Syrett, N.4
Goncalves, J.A.5
Hirshfeld, A.6
Ziliox, M.7
Sakmar, T.P.8
Sheves, M.9
Reeves, P.J.10
Smith, S.O.11
Eilers, M.12
-
2
-
-
0034607683
-
Evidence for long range allosteric interactions between the extracellular and cytoplasmic parts of bacteriorhodopsin from the mutant R82A and its second site revertant R82A/G231C
-
Alexiev U., Mollaaghababa R., Khorana H.G., Heyn M.P. Evidence for long range allosteric interactions between the extracellular and cytoplasmic parts of bacteriorhodopsin from the mutant R82A and its second site revertant R82A/G231C. J. Biol. Chem. 2000, 275:13431-13440.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13431-13440
-
-
Alexiev, U.1
Mollaaghababa, R.2
Khorana, H.G.3
Heyn, M.P.4
-
3
-
-
0037414446
-
Elucidation of the nature of the conformational changes of the EF-interhelical loop in bacteriorhodopsin and of the helix VIII on the cytoplasmic surface of bovine rhodopsin: a time-resolved fluorescence depolarization study
-
Alexiev U., Rimke I., Poehlmann T. Elucidation of the nature of the conformational changes of the EF-interhelical loop in bacteriorhodopsin and of the helix VIII on the cytoplasmic surface of bovine rhodopsin: a time-resolved fluorescence depolarization study. J. Mol. Biol. 2003, 328:705-719.
-
(2003)
J. Mol. Biol.
, vol.328
, pp. 705-719
-
-
Alexiev, U.1
Rimke, I.2
Poehlmann, T.3
-
4
-
-
0029113327
-
Time-resolved surface charge change on the cytoplasmic side of bacteriorhodopsin
-
Alexiev U., Scherrer P., Marti T., Khorana H.G., Heyn M.P. Time-resolved surface charge change on the cytoplasmic side of bacteriorhodopsin. FEBS Lett. 1995, 373:81-84.
-
(1995)
FEBS Lett.
, vol.373
, pp. 81-84
-
-
Alexiev, U.1
Scherrer, P.2
Marti, T.3
Khorana, H.G.4
Heyn, M.P.5
-
5
-
-
0027317273
-
Two different forms of metarhodopsin-II: Schiff base deprotonation precedes proton uptake and signaling state
-
Arnis S., Hofmann K.P. Two different forms of metarhodopsin-II: Schiff base deprotonation precedes proton uptake and signaling state. Proc. Natl. Acad. Sci. U. S. A. 1993, 90:7849-7853.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 7849-7853
-
-
Arnis, S.1
Hofmann, K.P.2
-
6
-
-
0028061193
-
A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin
-
Arnis S., Fahmy K., Hofmann K.P., Sakmar T.P. A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin. J. Biol. Chem. 1994, 269:23879-23881.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23879-23881
-
-
Arnis, S.1
Fahmy, K.2
Hofmann, K.P.3
Sakmar, T.P.4
-
8
-
-
0034948696
-
Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors
-
Ballesteros J.A., Shi L., Javitch J.A. Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors. Mol. Pharmacol. 2001, 60:1-19.
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 1-19
-
-
Ballesteros, J.A.1
Shi, L.2
Javitch, J.A.3
-
9
-
-
33845505655
-
Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes
-
Botelho A.V., Huber T., Sakmar T.P., Brown M.F. Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes. Biophys. J. 2006, 91:4464-4477.
-
(2006)
Biophys. J.
, vol.91
, pp. 4464-4477
-
-
Botelho, A.V.1
Huber, T.2
Sakmar, T.P.3
Brown, M.F.4
-
10
-
-
0036299067
-
Conformational change of the E-F interhelical loop in the M photointermediate of bacteriorhodopsin
-
Brown L.S., Needleman R., Lanyi J.K. Conformational change of the E-F interhelical loop in the M photointermediate of bacteriorhodopsin. J. Mol. Biol. 2002, 317:471-478.
-
(2002)
J. Mol. Biol.
, vol.317
, pp. 471-478
-
-
Brown, L.S.1
Needleman, R.2
Lanyi, J.K.3
-
11
-
-
0018894160
-
Light-induced interfacial potential in photoreceptor membranes
-
Cafiso D.S., Hubbell W.L. Light-induced interfacial potential in photoreceptor membranes. Biophys. J. 1980, 30:243-263.
-
(1980)
Biophys. J.
, vol.30
, pp. 243-263
-
-
Cafiso, D.S.1
Hubbell, W.L.2
-
12
-
-
0033613232
-
Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase
-
Cai K., Klein-Seetharaman J., Hwa J., Hubbell W.L., Khorana H.G. Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase. Biochemistry 1999, 38:12893-12898.
-
(1999)
Biochemistry
, vol.38
, pp. 12893-12898
-
-
Cai, K.1
Klein-Seetharaman, J.2
Hwa, J.3
Hubbell, W.L.4
Khorana, H.G.5
-
13
-
-
21844441860
-
Monomeric G-protein-coupled receptor as a functional unit
-
Chabre M., le Maire M. Monomeric G-protein-coupled receptor as a functional unit. Biochemistry 2005, 44:9395-9403.
-
(2005)
Biochemistry
, vol.44
, pp. 9395-9403
-
-
Chabre, M.1
le Maire, M.2
-
14
-
-
43749119868
-
Molecular dynamics simulation of rhodopsin point mutants at the cytoplasmic side of helices 3 and 6
-
Cordomi A., Ramon E., Garriga P., Perez J.J. Molecular dynamics simulation of rhodopsin point mutants at the cytoplasmic side of helices 3 and 6. J. Biomol. Struct. Dynam. 2008, 25:573-587.
-
(2008)
J. Biomol. Struct. Dynam.
, vol.25
, pp. 573-587
-
-
Cordomi, A.1
Ramon, E.2
Garriga, P.3
Perez, J.J.4
-
15
-
-
33644772378
-
Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin
-
Crocker E., Eilers M., Ahuja S., Hornak V., Hirshfeld A., Sheves M., Smith S.O. Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin. J. Mol. Biol. 2006, 357:163-172.
-
(2006)
J. Mol. Biol.
, vol.357
, pp. 163-172
-
-
Crocker, E.1
Eilers, M.2
Ahuja, S.3
Hornak, V.4
Hirshfeld, A.5
Sheves, M.6
Smith, S.O.7
-
16
-
-
0014697188
-
Internal protonation in retinylidene phosphatidylethanolamine and the red-shift in rhodopsin
-
Daemen F.J., Bonting S.L. Internal protonation in retinylidene phosphatidylethanolamine and the red-shift in rhodopsin. Nature 1969, 222:879-881.
-
(1969)
Nature
, vol.222
, pp. 879-881
-
-
Daemen, F.J.1
Bonting, S.L.2
-
17
-
-
46449137096
-
Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes
-
Dell'Orco D., Schmidt H. Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes. J. Phys. Chem. B 2008, 112:4419-4426.
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 4419-4426
-
-
Dell'Orco, D.1
Schmidt, H.2
-
18
-
-
77958039571
-
Energy landscapes as a tool to integrate GPCR structure, dynamics, and function
-
Deupi X., Kobilka B.K. Energy landscapes as a tool to integrate GPCR structure, dynamics, and function. Physiology 2010, 25:293-303.
-
(2010)
Physiology
, vol.25
, pp. 293-303
-
-
Deupi, X.1
Kobilka, B.K.2
-
19
-
-
0033555936
-
Conformational changes in rhodopsin movement of helix F detected by site-specific chemical labeling and fluorescence spectroscopy
-
Dunham T.D., Farrens D.L. Conformational changes in rhodopsin movement of helix F detected by site-specific chemical labeling and fluorescence spectroscopy. J. Biol. Chem. 1999, 274:1683-1690.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1683-1690
-
-
Dunham, T.D.1
Farrens, D.L.2
-
20
-
-
77955018405
-
Characterization of membrane protein non-native states 2. The SDS-unfolded states of rhodopsin
-
Dutta A., Kim T.Y., Moeller M., Wu J., Alexiev U., Klein-Seetharaman J. Characterization of membrane protein non-native states 2. The SDS-unfolded states of rhodopsin. Biochemistry 2010, 49:6329-6340.
-
(2010)
Biochemistry
, vol.49
, pp. 6329-6340
-
-
Dutta, A.1
Kim, T.Y.2
Moeller, M.3
Wu, J.4
Alexiev, U.5
Klein-Seetharaman, J.6
-
21
-
-
77955022753
-
Characterization of membrane protein non-native states 1. Extent of unfolding and aggregation of rhodopsin in the presence of chemical denaturants
-
Dutta A., Tirupula K.C., Alexiev U., Klein-Seetharaman J. Characterization of membrane protein non-native states 1. Extent of unfolding and aggregation of rhodopsin in the presence of chemical denaturants. Biochemistry 2010, 49:6317-6328.
-
(2010)
Biochemistry
, vol.49
, pp. 6317-6328
-
-
Dutta, A.1
Tirupula, K.C.2
Alexiev, U.3
Klein-Seetharaman, J.4
-
22
-
-
0033607270
-
Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor
-
Elling C.E., Thirstrup K., Holst B., Schwartz T.W. Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:12322-12327.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12322-12327
-
-
Elling, C.E.1
Thirstrup, K.2
Holst, B.3
Schwartz, T.W.4
-
23
-
-
0034695482
-
Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits
-
Ernst O.P., Meyer C.K., Marin E.P., Henklein P., Fu W.Y., Sakmar T.P., Hofmann K.P. Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits. J. Biol. Chem. 2000, 275:1937-1943.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1937-1943
-
-
Ernst, O.P.1
Meyer, C.K.2
Marin, E.P.3
Henklein, P.4
Fu, W.Y.5
Sakmar, T.P.6
Hofmann, K.P.7
-
24
-
-
0034730097
-
Transducin dependent protonation of glutamic acid 134 in rhodopsin
-
Fahmy K., Sakmar T., Siebert F. Transducin dependent protonation of glutamic acid 134 in rhodopsin. Biochemistry 2000, 39:10607-10612.
-
(2000)
Biochemistry
, vol.39
, pp. 10607-10612
-
-
Fahmy, K.1
Sakmar, T.2
Siebert, F.3
-
25
-
-
0029907599
-
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin
-
Farrens D.L., Altenbach C., Yang K., Hubbell W.L., Khorana H.G. Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science 1996, 274:768-770.
-
(1996)
Science
, vol.274
, pp. 768-770
-
-
Farrens, D.L.1
Altenbach, C.2
Yang, K.3
Hubbell, W.L.4
Khorana, H.G.5
-
26
-
-
0037426865
-
Atomic-force microscopy: rhodopsin dimers in native disc membranes
-
Fotiadis D., Liang Y., Filipek S., Saperstein D.A., Engel A., Palczewski K. Atomic-force microscopy: rhodopsin dimers in native disc membranes. Nature 2003, 421:127-128.
-
(2003)
Nature
, vol.421
, pp. 127-128
-
-
Fotiadis, D.1
Liang, Y.2
Filipek, S.3
Saperstein, D.A.4
Engel, A.5
Palczewski, K.6
-
27
-
-
0344406765
-
5,6F motif in the rhodopsin ground state and during activation
-
5,6F motif in the rhodopsin ground state and during activation. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:2290-2295.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 2290-2295
-
-
Fritze, O.1
Filipek, S.2
Kuksa, V.3
Palczewski, K.4
Hofmann, K.P.5
Ernst, O.P.6
-
28
-
-
0034673947
-
Phosphorylation modulates the affinity of light-activated rhodopsin for G protein and arrestin
-
Gibson S.K., Parkes J.H., Liebman P.A. Phosphorylation modulates the affinity of light-activated rhodopsin for G protein and arrestin. Biochemistry 2000, 39:5738-5749.
-
(2000)
Biochemistry
, vol.39
, pp. 5738-5749
-
-
Gibson, S.K.1
Parkes, J.H.2
Liebman, P.A.3
-
29
-
-
0028924619
-
Visual arrestin binding to rhodopsin diverse functional roles of positively charged residues within the phosphorylation-recognition region of arrestin
-
Gurevich V.V., Benovic J.L. Visual arrestin binding to rhodopsin diverse functional roles of positively charged residues within the phosphorylation-recognition region of arrestin. J. Biol. Chem. 1995, 270:6010-6016.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6010-6016
-
-
Gurevich, V.V.1
Benovic, J.L.2
-
30
-
-
0141919837
-
Multiple steps of phosphorylation of activated rhodopsin can account for the reproducibility of vertebrate rod single-photon responses
-
Hamer R.D., Nicholas S.C., Tranchina D., Liebman P.A., Lamb T.D. Multiple steps of phosphorylation of activated rhodopsin can account for the reproducibility of vertebrate rod single-photon responses. J. Gen. Physiol. 2003, 122:419-444.
-
(2003)
J. Gen. Physiol.
, vol.122
, pp. 419-444
-
-
Hamer, R.D.1
Nicholas, S.C.2
Tranchina, D.3
Liebman, P.A.4
Lamb, T.D.5
-
31
-
-
2642588172
-
Sequence of interactions in receptor-G protein coupling
-
Herrmann R., Heck M., Henklein P., Henklein P., Kleuss C., Hofmann K.P., Ernst O.P. Sequence of interactions in receptor-G protein coupling. J. Biol. Chem. 2004, 279:24283-24290.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24283-24290
-
-
Herrmann, R.1
Heck, M.2
Henklein, P.3
Henklein, P.4
Kleuss, C.5
Hofmann, K.P.6
Ernst, O.P.7
-
32
-
-
0033716604
-
Reaction control in bacteriorhodopsin: impact of Arg82 and Asp85 on the fast retinal isomerization, studied in the second site revertant Arg82Ala/Gly231Cys and various purple and blue forms of bacteriorhodopsin
-
Heyne K., Herbst J., Dominguez-Herradon B., Alexiev U., Diller R. Reaction control in bacteriorhodopsin: impact of Arg82 and Asp85 on the fast retinal isomerization, studied in the second site revertant Arg82Ala/Gly231Cys and various purple and blue forms of bacteriorhodopsin. J. Phys. Chem. B 2000, 104:6053-6058.
-
(2000)
J. Phys. Chem. B
, vol.104
, pp. 6053-6058
-
-
Heyne, K.1
Herbst, J.2
Dominguez-Herradon, B.3
Alexiev, U.4
Diller, R.5
-
33
-
-
0025141488
-
Transbilayer coupling mechanism for the formation of lipid asymmetry in biological membranes. Application to the photoreceptor disk membrane
-
Hubbell W.L. Transbilayer coupling mechanism for the formation of lipid asymmetry in biological membranes. Application to the photoreceptor disk membrane. Biophys. J. 1990, 57:99-108.
-
(1990)
Biophys. J.
, vol.57
, pp. 99-108
-
-
Hubbell, W.L.1
-
34
-
-
0037285444
-
Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking
-
Hubbell W.L., Altenbach C., Hubbell C.M., Khorana H.G. Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking. Adv. Protein Chem. 2003, 63:243-290.
-
(2003)
Adv. Protein Chem.
, vol.63
, pp. 243-290
-
-
Hubbell, W.L.1
Altenbach, C.2
Hubbell, C.M.3
Khorana, H.G.4
-
35
-
-
0034642188
-
Light-induced conformational changes of rhodopsin probed by fluorescent alexa594 immobilized on the cytoplasmic surface
-
Imamoto Y., Kataoka M., Tokunaga F., Palczewski K. Light-induced conformational changes of rhodopsin probed by fluorescent alexa594 immobilized on the cytoplasmic surface. Biochemistry 2000, 39:15225-15233.
-
(2000)
Biochemistry
, vol.39
, pp. 15225-15233
-
-
Imamoto, Y.1
Kataoka, M.2
Tokunaga, F.3
Palczewski, K.4
-
36
-
-
0035942229
-
Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: use of a chemically preactivated reagent
-
Itoh Y., Cai K., Khorana H.G. Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: use of a chemically preactivated reagent. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:4883-4887.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4883-4887
-
-
Itoh, Y.1
Cai, K.2
Khorana, H.G.3
-
37
-
-
23044489637
-
G-protein-coupled receptor domain overexpression in Halobacterium salinarum: long-range transmembrane interactions in heptahelical membrane proteins
-
Jaakola V.P., Rehn M., Moeller M., Alexiev U., Goldman A., Turner G.J. G-protein-coupled receptor domain overexpression in Halobacterium salinarum: long-range transmembrane interactions in heptahelical membrane proteins. Proteins 2005, 60:412-423.
-
(2005)
Proteins
, vol.60
, pp. 412-423
-
-
Jaakola, V.P.1
Rehn, M.2
Moeller, M.3
Alexiev, U.4
Goldman, A.5
Turner, G.J.6
-
38
-
-
0028017506
-
Identification of glutamic acid 113 as the Schiff base proton acceptor in the metarhodopsin II photointermediate of rhodopsin
-
Jager F., Fahmy K., Sakmar T.P., Siebert F. Identification of glutamic acid 113 as the Schiff base proton acceptor in the metarhodopsin II photointermediate of rhodopsin. Biochemistry 1994, 33:10878-10882.
-
(1994)
Biochemistry
, vol.33
, pp. 10878-10882
-
-
Jager, F.1
Fahmy, K.2
Sakmar, T.P.3
Siebert, F.4
-
39
-
-
0031043155
-
Rapid loop dynamics of Yersinia protein tyrosine phosphatases
-
Juszczak L.J., Zhang Z.Y., Wu D., Gottfried D.S., Eads D.D. Rapid loop dynamics of Yersinia protein tyrosine phosphatases. Biochemistry 1997, 36:2227-2236.
-
(1997)
Biochemistry
, vol.36
, pp. 2227-2236
-
-
Juszczak, L.J.1
Zhang, Z.Y.2
Wu, D.3
Gottfried, D.S.4
Eads, D.D.5
-
40
-
-
60849087699
-
Dissection of environmental changes at the cytoplasmic surface of light-activated bacteriorhodopsin and visual rhodopsin: sequence of spectrally silent steps
-
Kim T.Y., Moeller M., Winkler K., Kirchberg K., Alexiev U. Dissection of environmental changes at the cytoplasmic surface of light-activated bacteriorhodopsin and visual rhodopsin: sequence of spectrally silent steps. Photochem. Photobiol. 2009, 85:570-577.
-
(2009)
Photochem. Photobiol.
, vol.85
, pp. 570-577
-
-
Kim, T.Y.1
Moeller, M.2
Winkler, K.3
Kirchberg, K.4
Alexiev, U.5
-
41
-
-
66149122990
-
Monitoring the interaction of a single G-protein key binding site with rhodopsin disk membranes upon light activation
-
Kim T.Y., Uji-i H., Moeller M., Muls B., Hofkens J., Alexiev U. Monitoring the interaction of a single G-protein key binding site with rhodopsin disk membranes upon light activation. Biochemistry 2009, 48:3801-3803.
-
(2009)
Biochemistry
, vol.48
, pp. 3801-3803
-
-
Kim, T.Y.1
Uji-i, H.2
Moeller, M.3
Muls, B.4
Hofkens, J.5
Alexiev, U.6
-
42
-
-
34247191984
-
Picosecond multidimensional fluorescence spectroscopy: a tool to measure real-time protein dynamics during function
-
Kim T.Y., Winkler K., Alexiev U. Picosecond multidimensional fluorescence spectroscopy: a tool to measure real-time protein dynamics during function. Photochem. Photobiol. 2007, 83:378-384.
-
(2007)
Photochem. Photobiol.
, vol.83
, pp. 378-384
-
-
Kim, T.Y.1
Winkler, K.2
Alexiev, U.3
-
43
-
-
0017729574
-
A theory of fluorescence polarization decay in membranes
-
Kinosta K., Kawato S., Ikegami A. A theory of fluorescence polarization decay in membranes. Biophys. J. 1977, 20:289-305.
-
(1977)
Biophys. J.
, vol.20
, pp. 289-305
-
-
Kinosta, K.1
Kawato, S.2
Ikegami, A.3
-
44
-
-
76249091631
-
Functional interaction structures of the photochromic retinal protein rhodopsin
-
Kirchberg K., Kim T.Y., Haase S., Alexiev U. Functional interaction structures of the photochromic retinal protein rhodopsin. Photochem. Photobiol. Sci. 2010, 9:226-233.
-
(2010)
Photochem. Photobiol. Sci.
, vol.9
, pp. 226-233
-
-
Kirchberg, K.1
Kim, T.Y.2
Haase, S.3
Alexiev, U.4
-
45
-
-
0033609101
-
Signal transfer from rhodopsin to the G-protein: evidence for a. two-site sequential fit mechanism
-
Kisselev O.G., Meyer C.K., Heck M., Ernst O.P., Hofmann K.P. Signal transfer from rhodopsin to the G-protein: evidence for a. two-site sequential fit mechanism. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:4898-4903.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 4898-4903
-
-
Kisselev, O.G.1
Meyer, C.K.2
Heck, M.3
Ernst, O.P.4
Hofmann, K.P.5
-
46
-
-
3242804523
-
Sensory rhodopsin II and bacteriorhodopsin: light activated helix F movement
-
Klare J.P., Bordignon E., Engelhard M., Steinhoff H.J. Sensory rhodopsin II and bacteriorhodopsin: light activated helix F movement. Photochem. Photobiol. Sci. 2004, 3:543-547.
-
(2004)
Photochem. Photobiol. Sci.
, vol.3
, pp. 543-547
-
-
Klare, J.P.1
Bordignon, E.2
Engelhard, M.3
Steinhoff, H.J.4
-
47
-
-
0033598692
-
NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR
-
Klein-Seetharaman J., Getmanova E.V., Loewen M.C., Reeves P.J., Khorana H.G. NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:13744-13749.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 13744-13749
-
-
Klein-Seetharaman, J.1
Getmanova, E.V.2
Loewen, M.C.3
Reeves, P.J.4
Khorana, H.G.5
-
48
-
-
41949093679
-
Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors
-
Knierim B., Hofmann K.P., Gartner W., Hubbell W.L., Ernst O.P. Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors. J. Biol. Chem. 2008, 283:4967-4974.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4967-4974
-
-
Knierim, B.1
Hofmann, K.P.2
Gartner, W.3
Hubbell, W.L.4
Ernst, O.P.5
-
49
-
-
33644781659
-
Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface
-
Kota P., Reeves P.J., Rajbhandary U.L., Khorana H.G. Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:3054-3059.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 3054-3059
-
-
Kota, P.1
Reeves, P.J.2
Rajbhandary, U.L.3
Khorana, H.G.4
-
50
-
-
0037008008
-
Evidence that helix 8 of rhodopsin acts as a membrane-dependent conformational switch
-
Krishna A.G., Menon S.T., Terry T.J., Sakmar T.P. Evidence that helix 8 of rhodopsin acts as a membrane-dependent conformational switch. Biochemistry 2002, 41:8298-8309.
-
(2002)
Biochemistry
, vol.41
, pp. 8298-8309
-
-
Krishna, A.G.1
Menon, S.T.2
Terry, T.J.3
Sakmar, T.P.4
-
51
-
-
0020018797
-
Light-regulated binding of proteins to photoreceptor membranes and its use for the purification of several rod cell proteins
-
Kuhn H. Light-regulated binding of proteins to photoreceptor membranes and its use for the purification of several rod cell proteins. Methods Enzymol. 1982, 81:556-564.
-
(1982)
Methods Enzymol.
, vol.81
, pp. 556-564
-
-
Kuhn, H.1
-
52
-
-
27744493897
-
Structural observation of the primary isomerization in vision with femtosecond-stimulated Raman
-
Kukura P., McCamant D.W., Yoon S., Wandschneider D.B., Mathies R.A. Structural observation of the primary isomerization in vision with femtosecond-stimulated Raman. Science 2005, 310:1006-1009.
-
(2005)
Science
, vol.310
, pp. 1006-1009
-
-
Kukura, P.1
McCamant, D.W.2
Yoon, S.3
Wandschneider, D.B.4
Mathies, R.A.5
-
53
-
-
33646382407
-
Conformational states and dynamics of rhodopsin in micelles and bilayers
-
Kusnetzov A.K., Altenbach C., Hubbell W. Conformational states and dynamics of rhodopsin in micelles and bilayers. Biochemistry 2006, 45:5538-5550.
-
(2006)
Biochemistry
, vol.45
, pp. 5538-5550
-
-
Kusnetzov, A.K.1
Altenbach, C.2
Hubbell, W.3
-
54
-
-
33846631322
-
Linkage between the intramembrane H-bond network around aspartic acid 83 and the cytosolic environment of helix 8 in photoactivated rhodopsin
-
Lehmann N., Alexiev U., Fahmy K. Linkage between the intramembrane H-bond network around aspartic acid 83 and the cytosolic environment of helix 8 in photoactivated rhodopsin. J. Mol. Biol. 2007, 366:1129-1141.
-
(2007)
J. Mol. Biol.
, vol.366
, pp. 1129-1141
-
-
Lehmann, N.1
Alexiev, U.2
Fahmy, K.3
-
55
-
-
6344248639
-
Structure of bovine rhodopsin in a trigonal crystal form
-
Li J., Edwards P.C., Burghammer M., Villa C., Schertler G.F. Structure of bovine rhodopsin in a trigonal crystal form. J. Mol. Biol. 2004, 343:1409-1438.
-
(2004)
J. Mol. Biol.
, vol.343
, pp. 1409-1438
-
-
Li, J.1
Edwards, P.C.2
Burghammer, M.3
Villa, C.4
Schertler, G.F.5
-
56
-
-
0019201754
-
Effect of librational motion on fluorescence depolarization and nuclear magnetic resonance relaxation macromolecules and membranes
-
Lipari G., Szabo A. Effect of librational motion on fluorescence depolarization and nuclear magnetic resonance relaxation macromolecules and membranes. Biophys. J. 1980, 30:489-506.
-
(1980)
Biophys. J.
, vol.30
, pp. 489-506
-
-
Lipari, G.1
Szabo, A.2
-
57
-
-
25144510053
-
The role of Glu181 in the photoactivation of rhodopsin
-
Ludeke S., Beck M., Yan E.C., Sakmar T.P., Siebert F., Vogel R. The role of Glu181 in the photoactivation of rhodopsin. J. Mol. Biol. 2005, 353:345-356.
-
(2005)
J. Mol. Biol.
, vol.353
, pp. 345-356
-
-
Ludeke, S.1
Beck, M.2
Yan, E.C.3
Sakmar, T.P.4
Siebert, F.5
Vogel, R.6
-
58
-
-
0033536594
-
Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution
-
Luecke H., Schobert B., Richter H.T., Cartailler J.P., Lanyi J.K. Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution. Science 1999, 286:255-261.
-
(1999)
Science
, vol.286
, pp. 255-261
-
-
Luecke, H.1
Schobert, B.2
Richter, H.T.3
Cartailler, J.P.4
Lanyi, J.K.5
-
59
-
-
70350752268
-
Lipid protein interactions couple protonation to conformation in a conserved cytosolic domain of G protein-coupled receptors
-
Madathil S., Fahmy K. Lipid protein interactions couple protonation to conformation in a conserved cytosolic domain of G protein-coupled receptors. J. Biol. Chem. 2009, 284:28801-28809.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28801-28809
-
-
Madathil, S.1
Fahmy, K.2
-
60
-
-
56649097496
-
Two protonation switches control rhodopsin activation in membranes
-
Mahalingam M., Martinez-Mayorga K., Brown M.F., Vogel R. Two protonation switches control rhodopsin activation in membranes. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:17795-17800.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 17795-17800
-
-
Mahalingam, M.1
Martinez-Mayorga, K.2
Brown, M.F.3
Vogel, R.4
-
62
-
-
0033638108
-
Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites
-
Mendez A., Burns M.E., Roca A., Lem J., Wu L.W., Simon M.I., Baylor D.A., Chen J. Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron 2000, 28:153-164.
-
(2000)
Neuron
, vol.28
, pp. 153-164
-
-
Mendez, A.1
Burns, M.E.2
Roca, A.3
Lem, J.4
Wu, L.W.5
Simon, M.I.6
Baylor, D.A.7
Chen, J.8
-
63
-
-
0037172819
-
Light-induced changes in the structure and accessibility of the cytoplasmic loops of rhodopsin in the activated MII state
-
Mielke T., Alexiev U., Glasel M., Otto H., Heyn M.P. Light-induced changes in the structure and accessibility of the cytoplasmic loops of rhodopsin in the activated MII state. Biochemistry 2002, 41:7875-7884.
-
(2002)
Biochemistry
, vol.41
, pp. 7875-7884
-
-
Mielke, T.1
Alexiev, U.2
Glasel, M.3
Otto, H.4
Heyn, M.P.5
-
64
-
-
60849095807
-
Surface charge changes upon formation of the signaling state in visual rhodopsin
-
Moeller M., Alexiev U. Surface charge changes upon formation of the signaling state in visual rhodopsin. Photochem. Photobiol. 2009, 85:501-508.
-
(2009)
Photochem. Photobiol.
, vol.85
, pp. 501-508
-
-
Moeller, M.1
Alexiev, U.2
-
66
-
-
0033059345
-
Conformational change of helix G in the bacteriorhodopsin photocycle: investigation with heavy atom labeling and x-ray diffraction
-
Oka T., Kamikubo H., Tokunaga F., Lanyi J.K., Needleman R., Kataoka M. Conformational change of helix G in the bacteriorhodopsin photocycle: investigation with heavy atom labeling and x-ray diffraction. Biophys. J. 1999, 76:1018-1023.
-
(1999)
Biophys. J.
, vol.76
, pp. 1018-1023
-
-
Oka, T.1
Kamikubo, H.2
Tokunaga, F.3
Lanyi, J.K.4
Needleman, R.5
Kataoka, M.6
-
67
-
-
4344581120
-
The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure
-
Okada T., Sugihara M., Bondar A.N., Elstner M., Entel P., Buss V. The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure. J. Mol. Biol. 2004, 342:571-583.
-
(2004)
J. Mol. Biol.
, vol.342
, pp. 571-583
-
-
Okada, T.1
Sugihara, M.2
Bondar, A.N.3
Elstner, M.4
Entel, P.5
Buss, V.6
-
68
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K., Kumasaka T., Hori T., Behnke C.A., Motoshima H., Fox B.A., Le Trong I., Teller D.C., Okada T., Stenkamp R.E., Yamamoto M., Miyano M. Crystal structure of rhodopsin: A G protein-coupled receptor. Science 2000, 289:739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
69
-
-
47049130668
-
Crystal structure of the ligand-free G-protein-coupled receptor opsin
-
Park J.H., Scheerer P., Hofmann K.P., Choe H.W., Ernst O.P. Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature 2008, 454:183-187.
-
(2008)
Nature
, vol.454
, pp. 183-187
-
-
Park, J.H.1
Scheerer, P.2
Hofmann, K.P.3
Choe, H.W.4
Ernst, O.P.5
-
70
-
-
10844255797
-
Oligomerization of G protein-coupled receptors: past, present, and future
-
Park P.S., Filipek S., Wells J.W., Palczewski K. Oligomerization of G protein-coupled receptors: past, present, and future. Biochemistry 2004, 43:15643-15656.
-
(2004)
Biochemistry
, vol.43
, pp. 15643-15656
-
-
Park, P.S.1
Filipek, S.2
Wells, J.W.3
Palczewski, K.4
-
71
-
-
21144431897
-
Diversifying the repertoire of G protein-coupled receptors through oligomerization
-
Park P.S., Palczewski K. Diversifying the repertoire of G protein-coupled receptors through oligomerization. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:8793-8794.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 8793-8794
-
-
Park, P.S.1
Palczewski, K.2
-
72
-
-
2642583282
-
Acid-base equilibria in rhodopsin: dependence of the protonation state of Glu134 on its environment
-
Periole X., Ceruso M.A., Mehler E.L. Acid-base equilibria in rhodopsin: dependence of the protonation state of Glu134 on its environment. Biochemsitry 2004, 43:6858-6864.
-
(2004)
Biochemsitry
, vol.43
, pp. 6858-6864
-
-
Periole, X.1
Ceruso, M.A.2
Mehler, E.L.3
-
73
-
-
34548146523
-
G protein-coupled receptors self-assemble in dynamics simulations of model bilayers
-
Periole X., Huber T., Marrink S.J., Sakmar T.P. G protein-coupled receptors self-assemble in dynamics simulations of model bilayers. J. Am. Chem. Soc. 2007, 129:10126-10132.
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 10126-10132
-
-
Periole, X.1
Huber, T.2
Marrink, S.J.3
Sakmar, T.P.4
-
74
-
-
77956723634
-
Phototransduction in vertebrate rods and cones: molecular mechanisms of amplification, recovery and light adaptation
-
Elsevier Science BV
-
Pugh E.N.J., Lamb T.D. Phototransduction in vertebrate rods and cones: molecular mechanisms of amplification, recovery and light adaptation. Handbook of Biological Physics 2000, vol. 3:183-255. Elsevier Science BV.
-
(2000)
Handbook of Biological Physics
, vol.3
, pp. 183-255
-
-
Pugh, E.N.J.1
Lamb, T.D.2
-
75
-
-
2442548750
-
Identification of core amino acids stabilizing rhodopsin
-
Rader A.J., Anderson G., Isin B., Khorana H.G., Bahar I., Klein-Seetharaman J. Identification of core amino acids stabilizing rhodopsin. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:7246-7251.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 7246-7251
-
-
Rader, A.J.1
Anderson, G.2
Isin, B.3
Khorana, H.G.4
Bahar, I.5
Klein-Seetharaman, J.6
-
76
-
-
0035016932
-
Time-resolved detection of transient movement of helices F and G in doubly spin-labeled bacteriorhodopsin
-
Radzwill N., Gerwert K., Steinhoff H.J. Time-resolved detection of transient movement of helices F and G in doubly spin-labeled bacteriorhodopsin. Biophys. J. 2001, 80:2856-2866.
-
(2001)
Biophys. J.
, vol.80
, pp. 2856-2866
-
-
Radzwill, N.1
Gerwert, K.2
Steinhoff, H.J.3
-
77
-
-
0036532207
-
Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same
-
Sakmar T.P. Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same. Curr. Opin. Cell Biol. 2002, 14:189-195.
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 189-195
-
-
Sakmar, T.P.1
-
78
-
-
0343177634
-
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin
-
Sakmar T.P., Franke R.R., Khorana H.G. Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin. Proc. Natl. Acad. Sci. U. S. A. 1989, 86:8309-8313.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 8309-8313
-
-
Sakmar, T.P.1
Franke, R.R.2
Khorana, H.G.3
-
79
-
-
33750836895
-
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin
-
Salom D., Lodowski D.T., Stenkamp R.E., Le Trong I., Golczak M., Jastrzebska B., Harris T., Ballesteros J.A., Palczewski K. Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:16123-16128.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 16123-16128
-
-
Salom, D.1
Lodowski, D.T.2
Stenkamp, R.E.3
Le Trong, I.4
Golczak, M.5
Jastrzebska, B.6
Harris, T.7
Ballesteros, J.A.8
Palczewski, K.9
-
81
-
-
0342646933
-
Structural alterations for proton translocation in the M state of wild-type bacteriorhodopsin
-
Sass H.J., Bueldt G., Gessenich R., Hehn D., Neff D., Schlesinger R., Berendzen J., Ormos P. Structural alterations for proton translocation in the M state of wild-type bacteriorhodopsin. Nature 2000, 406:649-653.
-
(2000)
Nature
, vol.406
, pp. 649-653
-
-
Sass, H.J.1
Bueldt, G.2
Gessenich, R.3
Hehn, D.4
Neff, D.5
Schlesinger, R.6
Berendzen, J.7
Ormos, P.8
-
82
-
-
52949102889
-
Crystal structure of opsin in its G-protein-interacting conformation
-
Scheerer P., Park J.H., Hildebrand P.W., Kim Y.J., Krauss N., Choe H.W., Hofmann K.P., Ernst O.P. Crystal structure of opsin in its G-protein-interacting conformation. Nature 2008, 455:497-502.
-
(2008)
Nature
, vol.455
, pp. 497-502
-
-
Scheerer, P.1
Park, J.H.2
Hildebrand, P.W.3
Kim, Y.J.4
Krauss, N.5
Choe, H.W.6
Hofmann, K.P.7
Ernst, O.P.8
-
83
-
-
28444473536
-
Simulation of fluorescence anisotropy experiments: probing protein dynamics
-
Schroder G.F., Alexiev U., Grubmuller H. Simulation of fluorescence anisotropy experiments: probing protein dynamics. Biophys. J. 2005, 89:3757-3770.
-
(2005)
Biophys. J.
, vol.89
, pp. 3757-3770
-
-
Schroder, G.F.1
Alexiev, U.2
Grubmuller, H.3
-
84
-
-
0034632864
-
Molecular mechanism of vectorial proton translocation by bacteriorhodopsin
-
Subramaniam S., Henderson R. Molecular mechanism of vectorial proton translocation by bacteriorhodopsin. Nature 2000, 406:653-657.
-
(2000)
Nature
, vol.406
, pp. 653-657
-
-
Subramaniam, S.1
Henderson, R.2
-
85
-
-
77952906089
-
Structure and activation of the visual pigment rhodopsin
-
Smith S.O. Structure and activation of the visual pigment rhodopsin. Ann. Rev. Biophys. 2010, 39:309-328.
-
(2010)
Ann. Rev. Biophys.
, vol.39
, pp. 309-328
-
-
Smith, S.O.1
-
86
-
-
0001545374
-
Theory of fluorescence depolarization in macromolecules and membranes
-
Szabo A. Theory of fluorescence depolarization in macromolecules and membranes. J. Chem. Phys. 1984, 81:150-167.
-
(1984)
J. Chem. Phys.
, vol.81
, pp. 150-167
-
-
Szabo, A.1
-
87
-
-
0037024360
-
Identification of G protein-coupled receptor genes from the human genome sequence
-
Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S. Identification of G protein-coupled receptor genes from the human genome sequence. FEBS Lett. 2002, 520:97-101.
-
(2002)
FEBS Lett.
, vol.520
, pp. 97-101
-
-
Takeda, S.1
Kadowaki, S.2
Haga, T.3
Takaesu, H.4
Mitaku, S.5
-
88
-
-
0025139932
-
Distribution of charge on photoreceptor disc membranes and implications for charged lipid asymmetry
-
Tsui F.C., Sundberg S.A., Hubbell W.L. Distribution of charge on photoreceptor disc membranes and implications for charged lipid asymmetry. Biophys. J. 1990, 57:85-97.
-
(1990)
Biophys. J.
, vol.57
, pp. 85-97
-
-
Tsui, F.C.1
Sundberg, S.A.2
Hubbell, W.L.3
-
89
-
-
45649083187
-
Functional role of the "ionic lock" --an interhelical hydrogen-bond network in family A heptahelical receptors
-
Vogel R., Mahalingam M., Ludeke S., Huber T., Siebert F., Sakmar T.P. Functional role of the "ionic lock" --an interhelical hydrogen-bond network in family A heptahelical receptors. J. Mol. Biol. 2008, 380:648-655.
-
(2008)
J. Mol. Biol.
, vol.380
, pp. 648-655
-
-
Vogel, R.1
Mahalingam, M.2
Ludeke, S.3
Huber, T.4
Siebert, F.5
Sakmar, T.P.6
-
90
-
-
34247228082
-
Coupling of protonation switches during rhodopsin activation
-
Vogel R., Sakmar T.P., Sheves M., Siebert F. Coupling of protonation switches during rhodopsin activation. Photochem. Photobiol. 2007, 83:286-292.
-
(2007)
Photochem. Photobiol.
, vol.83
, pp. 286-292
-
-
Vogel, R.1
Sakmar, T.P.2
Sheves, M.3
Siebert, F.4
-
91
-
-
0034658269
-
Structure of the bacteriorhodopsin mutant F219L N intermediate revealed by electron crystallography
-
Vonck J. Structure of the bacteriorhodopsin mutant F219L N intermediate revealed by electron crystallography. EMBO J. 2000, 19:2152-2160.
-
(2000)
EMBO J.
, vol.19
, pp. 2152-2160
-
-
Vonck, J.1
-
92
-
-
36849105774
-
Effect of internal rotation on angular correlation functions
-
Wallach D. Effect of internal rotation on angular correlation functions. J. Chem. Phys. 1967, 47:5258-5268.
-
(1967)
J. Chem. Phys.
, vol.47
, pp. 5258-5268
-
-
Wallach, D.1
-
93
-
-
77951877209
-
Tracking G-protein coupled receptor activation using genetically encoded infrared probes
-
Ye S., Zaiteva E., Caltabiano G., Schertler G.F.X., Sakmar T.P., Deupi X., Vogel R. Tracking G-protein coupled receptor activation using genetically encoded infrared probes. Nature 2010, 464:1386-1390.
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(2010)
Nature
, vol.464
, pp. 1386-1390
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Ye, S.1
Zaiteva, E.2
Caltabiano, G.3
Schertler, G.F.X.4
Sakmar, T.P.5
Deupi, X.6
Vogel, R.7
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