-
1
-
-
0026800606
-
Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution
-
Aharonowitz Y., Cohen G., Martín J.F. Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution. Annu. Rev. Microbiol. 1992, 46:461-495.
-
(1992)
Annu. Rev. Microbiol.
, vol.46
, pp. 461-495
-
-
Aharonowitz, Y.1
Cohen, G.2
Martín, J.F.3
-
2
-
-
0023187586
-
High-frecuency transformation of Penicillium chrysogenum
-
Cantoral J.M., Díez B., Barredo J.L., Álvarez E., Martín J.F. High-frecuency transformation of Penicillium chrysogenum. Bio/Technology 1987, 5:494-497.
-
(1987)
Bio/Technology
, vol.5
, pp. 494-497
-
-
Cantoral, J.M.1
Díez, B.2
Barredo, J.L.3
Álvarez, E.4
Martín, J.F.5
-
3
-
-
0031817133
-
Characterization and nitrogen-source regulation at the transcriptional level of the gdhA gene of Aspergillus awamori encoding an NADP-dependent glutamate dehydrogenase
-
Cardoza R.E., Moralejo F.J., Gutiérrez S., Casqueiro J., Fierro F., Martín J.F. Characterization and nitrogen-source regulation at the transcriptional level of the gdhA gene of Aspergillus awamori encoding an NADP-dependent glutamate dehydrogenase. Curr. Genet. 1998, 34:50-59.
-
(1998)
Curr. Genet.
, vol.34
, pp. 50-59
-
-
Cardoza, R.E.1
Moralejo, F.J.2
Gutiérrez, S.3
Casqueiro, J.4
Fierro, F.5
Martín, J.F.6
-
4
-
-
0344958832
-
Gene targeting in Penicillium chrysogenum: disruption of the lys2 gene leads to penicillin overproduction
-
Casqueiro J., Gutierrez S., Bañuelos O., Hijarrubia M.J., Martín J.F. Gene targeting in Penicillium chrysogenum: disruption of the lys2 gene leads to penicillin overproduction. J. Bacteriol. 1999, 181:1181-1188.
-
(1999)
J. Bacteriol.
, vol.181
, pp. 1181-1188
-
-
Casqueiro, J.1
Gutierrez, S.2
Bañuelos, O.3
Hijarrubia, M.J.4
Martín, J.F.5
-
5
-
-
0027525974
-
Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans
-
Coque J.J., Liras P., Martin J.F. Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans. EMBO J. 1993, 12:631-639.
-
(1993)
EMBO J.
, vol.12
, pp. 631-639
-
-
Coque, J.J.1
Liras, P.2
Martin, J.F.3
-
6
-
-
0025026399
-
The cluster of penicillin biosynthetic genes. Identification and characterization of the pcbAB gene encoding the alpha-aminoadipyl-cysteinyl-valine synthetase and linkage to the pcbC and penDE genes
-
Díez B., Gutierrez S., Barredo J.L., van Solingen P., van der Voort L.H., Martín J.F. The cluster of penicillin biosynthetic genes. Identification and characterization of the pcbAB gene encoding the alpha-aminoadipyl-cysteinyl-valine synthetase and linkage to the pcbC and penDE genes. J. Biol. Chem. 1990, 265:16358-16365.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 16358-16365
-
-
Díez, B.1
Gutierrez, S.2
Barredo, J.L.3
van Solingen, P.4
van der Voort, L.H.5
Martín, J.F.6
-
7
-
-
14744279916
-
Compartmentalization and transport in beta-lactam antibiotics biosynthesis
-
Evers M.E., Trip H., van den Berg M.A., Bovenberg R.A., Driessen A.J. Compartmentalization and transport in beta-lactam antibiotics biosynthesis. Adv. Biochem. Eng. Biotechnol. 2004, 88:111-135.
-
(2004)
Adv. Biochem. Eng. Biotechnol.
, vol.88
, pp. 111-135
-
-
Evers, M.E.1
Trip, H.2
van den Berg, M.A.3
Bovenberg, R.A.4
Driessen, A.J.5
-
8
-
-
17144453678
-
The isopenicillin N acyltransferases of Aspergillus nidulans and Penicillium chrysogenum differ in their ability to maintain the 40-kDa alphabeta heterodimer in an undissociated form
-
Fernández F.J., Cardoza R.E., Montenegro E., Velasco J., Gutiérrez S., Martín J.F. The isopenicillin N acyltransferases of Aspergillus nidulans and Penicillium chrysogenum differ in their ability to maintain the 40-kDa alphabeta heterodimer in an undissociated form. Eur. J. Biochem. 2003, 270:1958-1968.
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1958-1968
-
-
Fernández, F.J.1
Cardoza, R.E.2
Montenegro, E.3
Velasco, J.4
Gutiérrez, S.5
Martín, J.F.6
-
9
-
-
0028085887
-
Molecular characterization of three loss-of-function mutations in the isopenicillin N-acyltransferase gene (penDE) of Penicillium chrysogenum
-
Fernández F.J., Gutiérrez S., Velasco J., Montenegro E., Marcos A.T., Martín J.F. Molecular characterization of three loss-of-function mutations in the isopenicillin N-acyltransferase gene (penDE) of Penicillium chrysogenum. J. Bacteriol. 1994, 176:4941-4948.
-
(1994)
J. Bacteriol.
, vol.176
, pp. 4941-4948
-
-
Fernández, F.J.1
Gutiérrez, S.2
Velasco, J.3
Montenegro, E.4
Marcos, A.T.5
Martín, J.F.6
-
10
-
-
84873990550
-
A vacuolar membrane protein affects drastically the biosynthesis of the ACV tripeptide and the beta-lactam pathway of Penicillium chrysogenum
-
Fernández-Aguado M., Teijeira F., Martín J.F., Ullán R.V. A vacuolar membrane protein affects drastically the biosynthesis of the ACV tripeptide and the beta-lactam pathway of Penicillium chrysogenum. Appl. Microbiol. Biotechnol. 2013, 97:795-808.
-
(2013)
Appl. Microbiol. Biotechnol.
, vol.97
, pp. 795-808
-
-
Fernández-Aguado, M.1
Teijeira, F.2
Martín, J.F.3
Ullán, R.V.4
-
11
-
-
84876679810
-
The transport of phenylacetic acid across the peroxisomal membrane is mediated by the PaaT protein in Penicillium chrysogenum
-
Fernández-Aguado M., Ullán R.V., Teijeira F., Rodríguez-Castro R., Martín J.F. The transport of phenylacetic acid across the peroxisomal membrane is mediated by the PaaT protein in Penicillium chrysogenum. Appl. Microbiol. Biotechnol. 2013, 97:3073-3084.
-
(2013)
Appl. Microbiol. Biotechnol.
, vol.97
, pp. 3073-3084
-
-
Fernández-Aguado, M.1
Ullán, R.V.2
Teijeira, F.3
Rodríguez-Castro, R.4
Martín, J.F.5
-
12
-
-
0028998750
-
The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences
-
Fierro F., Barredo J.L., Díez B., Gutiérrez S., Fernández F.J., Martín J.F. The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences. Proc. Natl. Acad. Sci. USA 1995, 92:6200-6204.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6200-6204
-
-
Fierro, F.1
Barredo, J.L.2
Díez, B.3
Gutiérrez, S.4
Fernández, F.J.5
Martín, J.F.6
-
13
-
-
33845318535
-
Import of peroxisomal membrane proteins: the interplay of Pex3p- and Pex19p-mediated interactions
-
Fujiki Y., Matsuzono Y., Matsuzaki T., Fransen M. Import of peroxisomal membrane proteins: the interplay of Pex3p- and Pex19p-mediated interactions. Biochim. Biophys. Acta 2006, 1763:1639-1646.
-
(2006)
Biochim. Biophys. Acta
, vol.1763
, pp. 1639-1646
-
-
Fujiki, Y.1
Matsuzono, Y.2
Matsuzaki, T.3
Fransen, M.4
-
14
-
-
82255194025
-
A single cluster of coregulated genes encodes the biosynthesis of the mycotoxins roquefortine C and meleagrin in Penicillium chrysogenum
-
García-Estrada C., Ullán R.V., Albillos S.M., Fernández-Bodega M.A., Durek P., von Dohren H., Martín J.F. A single cluster of coregulated genes encodes the biosynthesis of the mycotoxins roquefortine C and meleagrin in Penicillium chrysogenum. Chem. Biol. 2011, 18:1499-1512.
-
(2011)
Chem. Biol.
, vol.18
, pp. 1499-1512
-
-
García-Estrada, C.1
Ullán, R.V.2
Albillos, S.M.3
Fernández-Bodega, M.A.4
Durek, P.5
von Dohren, H.6
Martín, J.F.7
-
15
-
-
43149089553
-
The unprocessed preprotein form IATC103S of the isopenicillin N acyltransferase is transported inside peroxisomes and regulates its self-processing
-
García-Estrada C., Vaca I., Fierro F., Sjollema K., Veenhuis M., Martín J.F. The unprocessed preprotein form IATC103S of the isopenicillin N acyltransferase is transported inside peroxisomes and regulates its self-processing. Fungal Genet. Biol. 2008, 45:1043-1052.
-
(2008)
Fungal Genet. Biol.
, vol.45
, pp. 1043-1052
-
-
García-Estrada, C.1
Vaca, I.2
Fierro, F.3
Sjollema, K.4
Veenhuis, M.5
Martín, J.F.6
-
16
-
-
34547605349
-
In vivo transport of the intermediates of the penicillin biosynthetic pathway in tailored strains of Penicillium chrysogenum
-
Garcia-Estrada C., Vaca I., Lamas-Maceiras M., Martin J.F. In vivo transport of the intermediates of the penicillin biosynthetic pathway in tailored strains of Penicillium chrysogenum. Appl. Microbiol. Biotechnol. 2007, 76:169-182.
-
(2007)
Appl. Microbiol. Biotechnol.
, vol.76
, pp. 169-182
-
-
Garcia-Estrada, C.1
Vaca, I.2
Lamas-Maceiras, M.3
Martin, J.F.4
-
17
-
-
0026030134
-
Expression of the penDE gene of Penicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: production of benzylpenicillin by the transformants
-
Gutierrez S., Díez B., Álvarez E., Barredo J.L., Martín J.F. Expression of the penDE gene of Penicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: production of benzylpenicillin by the transformants. Mol. Gen. Genet. 1991, 225:56-64.
-
(1991)
Mol. Gen. Genet.
, vol.225
, pp. 56-64
-
-
Gutierrez, S.1
Díez, B.2
Álvarez, E.3
Barredo, J.L.4
Martín, J.F.5
-
18
-
-
0030779773
-
Expression of the cefG gene is limiting for cephalosporin biosynthesis in Acremonium chrysogenum
-
Gutiérrez S., Velasco J., Marcos A.T., Fernández F.J., Fierro F., Barredo J.L., Díez B., Martín J.F. Expression of the cefG gene is limiting for cephalosporin biosynthesis in Acremonium chrysogenum. Appl. Microbiol. Biotechnol. 1997, 48:606-614.
-
(1997)
Appl. Microbiol. Biotechnol.
, vol.48
, pp. 606-614
-
-
Gutiérrez, S.1
Velasco, J.2
Marcos, A.T.3
Fernández, F.J.4
Fierro, F.5
Barredo, J.L.6
Díez, B.7
Martín, J.F.8
-
19
-
-
61349128396
-
Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor
-
Harris D.M., Westerlaken I., Schipper D., van der Krogt Z.A., Gombert A.K., Sutherland J., Raamsdonk L.M., van den Berg M.A., Bovenberg R.A., Pronk J.T., Daran J.M. Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor. Metab. Eng. 2009, 11:125-137.
-
(2009)
Metab. Eng.
, vol.11
, pp. 125-137
-
-
Harris, D.M.1
Westerlaken, I.2
Schipper, D.3
van der Krogt, Z.A.4
Gombert, A.K.5
Sutherland, J.6
Raamsdonk, L.M.7
van den Berg, M.A.8
Bovenberg, R.A.9
Pronk, J.T.10
Daran, J.M.11
-
20
-
-
0037373068
-
Structural model for 12-helix transporters belonging to the major facilitator superfamily
-
Hirai T., Heymann J.A., Maloney P.C., Subramaniam S. Structural model for 12-helix transporters belonging to the major facilitator superfamily. J. Bacteriol. 2003, 185:1712-1718.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 1712-1718
-
-
Hirai, T.1
Heymann, J.A.2
Maloney, P.C.3
Subramaniam, S.4
-
21
-
-
58549084975
-
The global regulator LaeA controls penicillin biosynthesis, pigmentation and sporulation, but not roquefortine C synthesis in Penicillium chrysogenum
-
Kosalková K., García-Estrada C., Ullán R.V., Godio R.P., Feltrer R., Teijeira F., Mauriz E., Martín J.F. The global regulator LaeA controls penicillin biosynthesis, pigmentation and sporulation, but not roquefortine C synthesis in Penicillium chrysogenum. Biochimie 2009, 91:214-225.
-
(2009)
Biochimie
, vol.91
, pp. 214-225
-
-
Kosalková, K.1
García-Estrada, C.2
Ullán, R.V.3
Godio, R.P.4
Feltrer, R.5
Teijeira, F.6
Mauriz, E.7
Martín, J.F.8
-
22
-
-
33645581640
-
Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase
-
Lamas-Maceiras M., Vaca I., Rodríguez E., Casqueiro J., Martín J.F. Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase. Biochem. J. 2006, 395:147-155.
-
(2006)
Biochem. J.
, vol.395
, pp. 147-155
-
-
Lamas-Maceiras, M.1
Vaca, I.2
Rodríguez, E.3
Casqueiro, J.4
Martín, J.F.5
-
23
-
-
0032980845
-
Biosynthesis and molecular genetics of cephamycins. Cephamycins produced by actinomycetes
-
Liras P. Biosynthesis and molecular genetics of cephamycins. Cephamycins produced by actinomycetes. Antonie Van Leeuwenhoek 1999, 75:109-124.
-
(1999)
Antonie Van Leeuwenhoek
, vol.75
, pp. 109-124
-
-
Liras, P.1
-
24
-
-
20444502568
-
Secretion systems for secondary metabolites: how producer cells send out messages of intercellular communication
-
Martin J.F., Casqueiro J., Liras P. Secretion systems for secondary metabolites: how producer cells send out messages of intercellular communication. Curr. Opin. Microbiol. 2005, 8:282-293.
-
(2005)
Curr. Opin. Microbiol.
, vol.8
, pp. 282-293
-
-
Martin, J.F.1
Casqueiro, J.2
Liras, P.3
-
25
-
-
84873987111
-
Genes encoding penicillin and cephalosporin biosynthesis in Acremonium chrysogenum
-
Gupta, V.K., Ayyachamy, M. (Eds.), Biotechnology of Fungal Genes. Science Publishers (An Imprint of Edenbridge Ltd., British Channel Islands), Enfield, New Hampshire 03478, USA.
-
Martín, J.F., García-Estrada, C., Ullán, R.V., 2012a. Genes encoding penicillin and cephalosporin biosynthesis in Acremonium chrysogenum: two separate clusters are required. In: Gupta, V.K., Ayyachamy, M. (Eds.), Biotechnology of Fungal Genes. Science Publishers (An Imprint of Edenbridge Ltd., British Channel Islands), Enfield, New Hampshire 03478, USA., pp. 113-138.
-
(2012)
two separate clusters are required
, pp. 113-138
-
-
Martín, J.F.1
García-Estrada, C.2
Ullán, R.V.3
-
26
-
-
84876552378
-
Transport of substrates into peroxisomes: the paradigm of β-lactam biosynthetic intermediates
-
Martín J.F., García-Estrada C., Ullán R.V. Transport of substrates into peroxisomes: the paradigm of β-lactam biosynthetic intermediates. BioMol. Concept. 2013, 4:197-211.
-
(2013)
BioMol. Concept.
, vol.4
, pp. 197-211
-
-
Martín, J.F.1
García-Estrada, C.2
Ullán, R.V.3
-
27
-
-
77953172576
-
Regulation and compartmentalization of beta-lactam biosynthesis
-
Martín J.F., Ullán R.V., García-Estrada C. Regulation and compartmentalization of beta-lactam biosynthesis. Microb. Biotechnol. 2010, 3:285-299.
-
(2010)
Microb. Biotechnol.
, vol.3
, pp. 285-299
-
-
Martín, J.F.1
Ullán, R.V.2
García-Estrada, C.3
-
28
-
-
84859833488
-
Role of peroxisomes in the biosynthesis and secretion of beta-lactams and other secondary metabolites
-
Martín J.F., Ullán R.V., García-Estrada C. Role of peroxisomes in the biosynthesis and secretion of beta-lactams and other secondary metabolites. J. Ind. Microbiol. Biotechnol. 2012, 39:367-382.
-
(2012)
J. Ind. Microbiol. Biotechnol.
, vol.39
, pp. 367-382
-
-
Martín, J.F.1
Ullán, R.V.2
García-Estrada, C.3
-
29
-
-
0026057879
-
Localization of the pathway of the penicillin biosynthesis in Penicillium chrysogenum
-
Müller W.H., van der Krift T.P., Krouwer A.J., Wosten H.A., van der Voort L.H., Smaal E.B., Verkleij A.J. Localization of the pathway of the penicillin biosynthesis in Penicillium chrysogenum. EMBO J. 1991, 10:489-495.
-
(1991)
EMBO J.
, vol.10
, pp. 489-495
-
-
Müller, W.H.1
van der Krift, T.P.2
Krouwer, A.J.3
Wosten, H.A.4
van der Voort, L.H.5
Smaal, E.B.6
Verkleij, A.J.7
-
30
-
-
84873718227
-
Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation
-
Ozcengiz G., Demain A.L. Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation. Biotechnol. Adv. 2013, 31:287-311.
-
(2013)
Biotechnol. Adv.
, vol.31
, pp. 287-311
-
-
Ozcengiz, G.1
Demain, A.L.2
-
32
-
-
0242291983
-
Multidrug efflux pumps and resistance: regulation and evolution
-
Paulsen I.T. Multidrug efflux pumps and resistance: regulation and evolution. Curr. Opin. Microbiol. 2003, 6:446-451.
-
(2003)
Curr. Opin. Microbiol.
, vol.6
, pp. 446-451
-
-
Paulsen, I.T.1
-
34
-
-
0027408932
-
Topology, structure and evolution of two families of proteins involved in antibiotic and antiseptic resistance in eukaryotes and prokaryotes-an analysis
-
Paulsen I.T., Skurray R.A. Topology, structure and evolution of two families of proteins involved in antibiotic and antiseptic resistance in eukaryotes and prokaryotes-an analysis. Gene 1993, 124:1-11.
-
(1993)
Gene
, vol.124
, pp. 1-11
-
-
Paulsen, I.T.1
Skurray, R.A.2
-
35
-
-
0026779753
-
An upstream activating sequence from the Aspergillus nidulans gpdA gene
-
Punt P.J., Kramer C., Kuyvenhoven A., Pouwels P.H., van den Hondel C.A. An upstream activating sequence from the Aspergillus nidulans gpdA gene. Gene 1992, 120:67-73.
-
(1992)
Gene
, vol.120
, pp. 67-73
-
-
Punt, P.J.1
Kramer, C.2
Kuyvenhoven, A.3
Pouwels, P.H.4
van den Hondel, C.A.5
-
36
-
-
84861193393
-
The major facilitator superfamily (MFS) revisited
-
Reddy V.S., Shlykov M.A., Castillo R., Sun E.I., Saier M.H. The major facilitator superfamily (MFS) revisited. FEBS J. 2012, 279:2022-2035.
-
(2012)
FEBS J.
, vol.279
, pp. 2022-2035
-
-
Reddy, V.S.1
Shlykov, M.A.2
Castillo, R.3
Sun, E.I.4
Saier, M.H.5
-
37
-
-
3042724871
-
Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals
-
Rottensteiner H., Kramer A., Lorenzen S., Stein K., Landgraf C., Volkmer-Engert R., Erdmann R. Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals. Mol. Biol. Cell 2004, 15:3406-3417.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3406-3417
-
-
Rottensteiner, H.1
Kramer, A.2
Lorenzen, S.3
Stein, K.4
Landgraf, C.5
Volkmer-Engert, R.6
Erdmann, R.7
-
38
-
-
0026102071
-
Distinct cis-acting signals enhance 3' endpoint formation of cyc1 mRNA in the yeast Saccharomyces cerevisiae
-
Russo P., Li W.Z., Hampsey D.M., Zaret K.S., Sherman F. Distinct cis-acting signals enhance 3' endpoint formation of cyc1 mRNA in the yeast Saccharomyces cerevisiae. EMBO J. 1991, 10:563-571.
-
(1991)
EMBO J.
, vol.10
, pp. 563-571
-
-
Russo, P.1
Li, W.Z.2
Hampsey, D.M.3
Zaret, K.S.4
Sherman, F.5
-
39
-
-
0033222857
-
The major facilitator superfamily
-
Saier M.H., Beatty J.T., Goffeau A., Harley K.T., Heijne W.H., Huang S.C., Jack D.L., Jahn P.S., Lew K., Liu J., Pao S.S., Paulsen I.T., Tseng T.T., Virk P.S. The major facilitator superfamily. J. Mol. Microbiol. Biotechnol. 1999, 1:257-279.
-
(1999)
J. Mol. Microbiol. Biotechnol.
, vol.1
, pp. 257-279
-
-
Saier, M.H.1
Beatty, J.T.2
Goffeau, A.3
Harley, K.T.4
Heijne, W.H.5
Huang, S.C.6
Jack, D.L.7
Jahn, P.S.8
Lew, K.9
Liu, J.10
Pao, S.S.11
Paulsen, I.T.12
Tseng, T.T.13
Virk, P.S.14
-
40
-
-
84877826485
-
Improving penicillin biosynthesis in Penicillium chrysogenum by glyoxalase overproduction
-
Scheckhuber C.Q., Veenhuis M., van der Klei I.J. Improving penicillin biosynthesis in Penicillium chrysogenum by glyoxalase overproduction. Metab. Eng. 2013, 18:36-43.
-
(2013)
Metab. Eng.
, vol.18
, pp. 36-43
-
-
Scheckhuber, C.Q.1
Veenhuis, M.2
van der Klei, I.J.3
-
41
-
-
80052030355
-
CefR modulates transporters of beta-lactam intermediates preventing the loss of penicillins to the broth and increases cephalosporin production in Acremonium chrysogenum
-
Teijeira F., Ullán R.V., Fernández-Aguado M., Martín J.F. CefR modulates transporters of beta-lactam intermediates preventing the loss of penicillins to the broth and increases cephalosporin production in Acremonium chrysogenum. Metab. Eng. 2011, 13:532-543.
-
(2011)
Metab. Eng.
, vol.13
, pp. 532-543
-
-
Teijeira, F.1
Ullán, R.V.2
Fernández-Aguado, M.3
Martín, J.F.4
-
42
-
-
59849116926
-
The transporter CefM involved in translocation of biosynthetic intermediates is essential for cephalosporin production
-
Teijeira F., Ullán R.V., Guerra S.M., García-Estrada C., Vaca I., Martín J.F. The transporter CefM involved in translocation of biosynthetic intermediates is essential for cephalosporin production. Biochem. J. 2009, 418:113-124.
-
(2009)
Biochem. J.
, vol.418
, pp. 113-124
-
-
Teijeira, F.1
Ullán, R.V.2
Guerra, S.M.3
García-Estrada, C.4
Vaca, I.5
Martín, J.F.6
-
43
-
-
33947267597
-
Deacetylcephalosporin C production in Penicillium chrysogenum by expression of the isopenicillin N epimerization, ring expansion, and acetylation genes
-
Ullán R.V., Campoy S., Casqueiro J., Fernández F.J., Martín J.F. Deacetylcephalosporin C production in Penicillium chrysogenum by expression of the isopenicillin N epimerization, ring expansion, and acetylation genes. Chem. Biol. 2007, 14:329-339.
-
(2007)
Chem. Biol.
, vol.14
, pp. 329-339
-
-
Ullán, R.V.1
Campoy, S.2
Casqueiro, J.3
Fernández, F.J.4
Martín, J.F.5
-
44
-
-
0037195848
-
A novel epimerization system in fungal secondary metabolism involved in the conversion of isopenicillin N into penicillin N in Acremonium chrysogenum
-
Ullán R.V., Casqueiro J., Bañuelos O., Fernández F.J., Gutierrez S., Martín J.F. A novel epimerization system in fungal secondary metabolism involved in the conversion of isopenicillin N into penicillin N in Acremonium chrysogenum. J. Biol. Chem. 2002, 277:46216-46225.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 46216-46225
-
-
Ullán, R.V.1
Casqueiro, J.2
Bañuelos, O.3
Fernández, F.J.4
Gutierrez, S.5
Martín, J.F.6
-
45
-
-
13244249752
-
Expression of cefD2 and the conversion of isopenicillin N into penicillin N by the two-component epimerase system are rate-limiting steps in cephalosporin biosynthesis
-
Ullán R.V., Casqueiro J., Naranjo L., Vaca I., Martín J.F. Expression of cefD2 and the conversion of isopenicillin N into penicillin N by the two-component epimerase system are rate-limiting steps in cephalosporin biosynthesis. Mol. Genet. Genomics 2004, 272:562-570.
-
(2004)
Mol. Genet. Genomics
, vol.272
, pp. 562-570
-
-
Ullán, R.V.1
Casqueiro, J.2
Naranjo, L.3
Vaca, I.4
Martín, J.F.5
-
46
-
-
50549086676
-
RNA-silencing in Penicillium chrysogenum and Acremonium chrysogenum: validation studies using beta-lactam genes expression
-
Ullán R.V., Godio R.P., Teijeira F., Vaca I., García-Estrada C., Feltrer R., Kosalková K., Martín J.F. RNA-silencing in Penicillium chrysogenum and Acremonium chrysogenum: validation studies using beta-lactam genes expression. J. Microbiol. Methods 2008, 75:209-218.
-
(2008)
J. Microbiol. Methods
, vol.75
, pp. 209-218
-
-
Ullán, R.V.1
Godio, R.P.2
Teijeira, F.3
Vaca, I.4
García-Estrada, C.5
Feltrer, R.6
Kosalková, K.7
Martín, J.F.8
-
47
-
-
0036323756
-
The cefT gene of Acremonium chrysogenum C10 encodes a putative multidrug efflux pump protein that significantly increases cephalosporin C production
-
Ullán R.V., Liu G., Casqueiro J., Gutierrez S., Bañuelos O., Martín J.F. The cefT gene of Acremonium chrysogenum C10 encodes a putative multidrug efflux pump protein that significantly increases cephalosporin C production. Mol. Genet. Genomics 2002, 267:673-683.
-
(2002)
Mol. Genet. Genomics
, vol.267
, pp. 673-683
-
-
Ullán, R.V.1
Liu, G.2
Casqueiro, J.3
Gutierrez, S.4
Bañuelos, O.5
Martín, J.F.6
-
48
-
-
78649608529
-
Characterization of a novel peroxisome membrane protein essential for conversion of isopenicillin N into cephalosporin C
-
Ullán R.V., Teijeira F., Guerra S.M., Vaca I., Martín J.F. Characterization of a novel peroxisome membrane protein essential for conversion of isopenicillin N into cephalosporin C. Biochem. J. 2010, 432:227-236.
-
(2010)
Biochem. J.
, vol.432
, pp. 227-236
-
-
Ullán, R.V.1
Teijeira, F.2
Guerra, S.M.3
Vaca, I.4
Martín, J.F.5
-
49
-
-
50849126781
-
Expression of the Acremonium chrysogenum cefT gene in Penicillum chrysogenum indicates that it encodes an hydrophilic beta-lactam transporter
-
Ullán R.V., Teijeira F., Martin J.F. Expression of the Acremonium chrysogenum cefT gene in Penicillum chrysogenum indicates that it encodes an hydrophilic beta-lactam transporter. Curr. Genet. 2008, 54:153-161.
-
(2008)
Curr. Genet.
, vol.54
, pp. 153-161
-
-
Ullán, R.V.1
Teijeira, F.2
Martin, J.F.3
-
50
-
-
0033020288
-
Compartmentalization and transport in beta-lactam antibiotic biosynthesis by filamentous fungi
-
van de Kamp M., Driessen A.J., Konings W.N. Compartmentalization and transport in beta-lactam antibiotic biosynthesis by filamentous fungi. Antonie Van Leeuwenhoek 1999, 75:41-78.
-
(1999)
Antonie Van Leeuwenhoek
, vol.75
, pp. 41-78
-
-
van de Kamp, M.1
Driessen, A.J.2
Konings, W.N.3
-
51
-
-
0036392191
-
Delta-(l-alpha-Aminoadipyl)-l-cysteinyl-d-valine synthetase, that mediates the first committed step in penicillin biosynthesis, is a cytosolic enzyme
-
van der Lende T.R., van de Kamp M., Berg M., Sjollema K., Bovenberg R.A., Veenhuis M., Konings W.N., Driessen A.J. Delta-(l-alpha-Aminoadipyl)-l-cysteinyl-d-valine synthetase, that mediates the first committed step in penicillin biosynthesis, is a cytosolic enzyme. Fungal Genet. Biol. 2002, 37:49-55.
-
(2002)
Fungal Genet. Biol.
, vol.37
, pp. 49-55
-
-
van der Lende, T.R.1
van de Kamp, M.2
Berg, M.3
Sjollema, K.4
Bovenberg, R.A.5
Veenhuis, M.6
Konings, W.N.7
Driessen, A.J.8
-
52
-
-
84862174574
-
Metabolic engineering of beta-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis
-
Veiga T., Gombert A.K., Landes N., Verhoeven M.D., Kiel J.A., Krikken A.M., Nijland J.G., Touw H., Luttik M.A., van der Toorn J.C., Driessen A.J., Bovenberg R.A., van den Berg M.A., van der Klei I.J., Pronk J.T., Daran J.M. Metabolic engineering of beta-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis. Metab. Eng. 2012, 14:437-448.
-
(2012)
Metab. Eng.
, vol.14
, pp. 437-448
-
-
Veiga, T.1
Gombert, A.K.2
Landes, N.3
Verhoeven, M.D.4
Kiel, J.A.5
Krikken, A.M.6
Nijland, J.G.7
Touw, H.8
Luttik, M.A.9
van der Toorn, J.C.10
Driessen, A.J.11
Bovenberg, R.A.12
van den Berg, M.A.13
van der Klei, I.J.14
Pronk, J.T.15
Daran, J.M.16
-
53
-
-
34447095636
-
Molecular cloning and functional identification of a novel phenylacetyl-CoA ligase gene from Penicillium chrysogenum
-
Wang F.Q., Liu J., Dai M., Ren Z.H., Su C.Y., He J.G. Molecular cloning and functional identification of a novel phenylacetyl-CoA ligase gene from Penicillium chrysogenum. Biochem. Biophys. Res. Commun. 2007, 360:453-458.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.360
, pp. 453-458
-
-
Wang, F.Q.1
Liu, J.2
Dai, M.3
Ren, Z.H.4
Su, C.Y.5
He, J.G.6
-
54
-
-
84867913650
-
The ABC transporter ABC40 encodes a phenylacetic acid export system in Penicillium chrysogenum
-
Weber S.S., Kovalchuk A., Bovenberg R.A., Driessen A.J. The ABC transporter ABC40 encodes a phenylacetic acid export system in Penicillium chrysogenum. Fungal Genet. Biol. 2012, 49:915-921.
-
(2012)
Fungal Genet. Biol.
, vol.49
, pp. 915-921
-
-
Weber, S.S.1
Kovalchuk, A.2
Bovenberg, R.A.3
Driessen, A.J.4
-
55
-
-
84874258738
-
Structural advances for the major facilitator superfamily (MFS) transporters
-
Yan N. Structural advances for the major facilitator superfamily (MFS) transporters. Trends Biochem. Sci. 2013, 38:151-159.
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 151-159
-
-
Yan, N.1
-
56
-
-
84870255860
-
Amplification of an MFS transporter encoding gene penT significantly stimulates penicillin production and enhances the sensitivity of Penicillium chrysogenum to phenylacetic acid
-
Yang J., Xu X., Liu G. Amplification of an MFS transporter encoding gene penT significantly stimulates penicillin production and enhances the sensitivity of Penicillium chrysogenum to phenylacetic acid. J. Genet. Genomics 2012, 39:593-602.
-
(2012)
J. Genet. Genomics
, vol.39
, pp. 593-602
-
-
Yang, J.1
Xu, X.2
Liu, G.3
-
57
-
-
79960058417
-
Cloning and characterization of a novel CoA-ligase gene from Penicillium chrysogenum
-
Yu Z.L., Liu J., Wang F.Q., Dai M., Zhao B.H., He J.G., Zhang H. Cloning and characterization of a novel CoA-ligase gene from Penicillium chrysogenum. Folia Microbiol. (Praha) 2011, 56:246-252.
-
(2011)
Folia Microbiol. (Praha)
, vol.56
, pp. 246-252
-
-
Yu, Z.L.1
Liu, J.2
Wang, F.Q.3
Dai, M.4
Zhao, B.H.5
He, J.G.6
Zhang, H.7
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