δ-(L-α-Aminoadipyl)-L-cysteinyl-D-valine synthetase, that mediates the first committed step in penicillin biosynthesis, is a cytosolic enzyme

Fungal Genetics and Biology

Volumn 37, Issue 1, 2002, Pages 49-55

  Van Der Lende, Ted R ^a   Van De Kamp, Mart ^a   Van Den Berg, Marco ^b   Sjollema, Klaas ^a   Bovenberg, Roel A L ^b   Veenhuis, Marten ^a   Konings, Wil N ^a   Driessen, Arnold J M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b DSM RESOLVE   (Netherlands)

Author keywords

Lactam antibiotics; Compartmentalization; Penicillin biosynthesis; Peptide synthetase; Secondary metabolism; Vacuole

Indexed keywords

2 AMINOADIPIC ACID; ACYLTRANSFERASE; AMINO ACID DERIVATIVE; CELL ENZYME; CYSTEINE; DELTA (ALPHA AMINOADIPYL)CYSTEINYL DEXTRO VALINE SYNTHETASE; ISOPENICILLIN N SYNTHETASE; PENICILLIN G; SYNTHETASE; TRIPEPTIDE; UNCLASSIFIED DRUG; VALINE;

ARTICLE; CATALYSIS; CELL COMPARTMENTALIZATION; CELL FRACTIONATION; CELL VACUOLE; CONTROLLED STUDY; CYTOSOL; DRUG SYNTHESIS; ENZYME LOCALIZATION; FUNGAL MORPHOLOGY; IMMUNOELECTRON MICROSCOPY; MICROBODY; MOLECULAR WEIGHT; NONHUMAN; PENICILLIUM CHRYSOGENUM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN POLYMERIZATION;

CYTOSOL; ENZYME STABILITY; MICROBODIES; MICROSCOPY, ELECTRON; PENICILLINS; PENICILLIUM CHRYSOGENUM; PEPTIDE SYNTHASES; PROTOPLASTS; SUBCELLULAR FRACTIONS; VACUOLES;

PENICILLIUM; PENICILLIUM CHRYSOGENUM;

EID: 0036392191     PISSN: 10871845     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1087-1845(02)00036-1     Document Type: Article

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