The transporter CefM involved in translocation of biosynthetic intermediates is essential for cephalosporin production

Biochemical Journal

Volumn 418, Issue 1, 2009, Pages 113-124

  Teijeira, Fernando ^a   Ullán, Ricardo V ^b   Guerra, Susana M ^a   García Estrada, Carlos ^b   Vaca, Inmaculada ^b   Martín, Juan F ^a,b  

^a UNIVERSITY OF LEÓN   (Spain)

^b Institute of Biotechnology INBIOTEC Parque Científico de León   (Spain)

Author keywords

Acremonium chrysogenum; CefM transporter; Cephalosporin C biosynthesis; Compartmentalization; Isopenicillin N; Translocation of penicillin N from microbodies

Indexed keywords

ACREMONIUM CHRYSOGENUM; CEFM TRANSPORTER; CEPHALOSPORIN C BIOSYNTHESIS; COMPARTMENTALIZATION; ISOPENICILLIN N; TRANSLOCATION OF PENICILLIN N FROM MICROBODIES;

ACTIVATION ANALYSIS; BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; BIOSYNTHESIS; CYTOLOGY; GENE ENCODING;

SEWAGE TREATMENT PLANTS;

ADICILLIN; CARRIER PROTEIN; CEPHALOSPORIN C; CEPHALOSPORIN DERIVATIVE; DEACETOXYCEPHALOSPORIN C; DEACETYLCEPHALOSPORIN C; FUNGAL PROTEIN; GREEN FLUORESCENT PROTEIN; ISOPENICILLIN N COENZYME A EPIMERASE; ISOPENICILLIN N COENZYME A SYNTHASE; ISOPENICILLIN N SYNTHETASE; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

ARTICLE; CEPHALOSPORIUM ACREMONIUM; CONTROLLED STUDY; CYTOSOL; DRUG SYNTHESIS; FUNGUS CULTURE; FUNGUS HYPHAE; FUNGUS SPORE; GENE CLUSTER; GENE DISRUPTION; GENE INACTIVATION; GENE MUTATION; GENETIC COMPLEMENTATION; MICROBODY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PEROXISOME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; ACREMONIUM; AMINO ACID SEQUENCE; BIOSYNTHESIS; CHEMISTRY; GENETICS; INTRACELLULAR MEMBRANE; METABOLISM; MOLECULAR GENETICS; MUTATION; REPORTER GENE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ACREMONIUM CHRYSOGENUM;

ACREMONIUM; AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CEPHALOSPORINS; FUNGAL PROTEINS; GENES, REPORTER; INTRACELLULAR MEMBRANES; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 59849116926     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20081180     Document Type: Article

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