메뉴 건너뛰기




Volumn 388, Issue 1-2, 2014, Pages 157-172

Antiproliferative and apoptotic-inducing potential of ellagic acid against 1,2-dimethyl hydrazine-induced colon tumorigenesis in Wistar rats

Author keywords

Apoptosis; Colon cancer; Dimethylhydrazine; Ellagic acid; Proliferation

Indexed keywords

1,2-DIMETHYLHYDRAZINE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLON; COLONIC NEOPLASMS; CYCLIN D1; ELLAGIC ACID; MALE; MAST CELLS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84893839960     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1907-0     Document Type: Article
Times cited : (27)

References (78)
  • 3
    • 84855515509 scopus 로고    scopus 로고
    • Chemoprevention in colorectal cancer where we stand and what we have learned from twenty year's experience
    • 22129884 10.1016/j.surge.2011.07.003
    • Boghossian S, Hawash A (2011) Chemoprevention in colorectal cancer where we stand and what we have learned from twenty year's experience. Surgeon 10:43-52
    • (2011) Surgeon , vol.10 , pp. 43-52
    • Boghossian, S.1    Hawash, A.2
  • 6
    • 24944522546 scopus 로고    scopus 로고
    • Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin)
    • DOI 10.1093/carcin/bgi089
    • Volate SR, Davenport DM, Muga SJ, Wargovich MJ (2005) Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin). Carcinogenesis 26:1450-1456 (Pubitemid 41417889)
    • (2005) Carcinogenesis , vol.26 , Issue.8 , pp. 1450-1456
    • Volate, S.R.1    Davenport, D.M.2    Muga, S.J.3    Wargovich, M.J.4
  • 7
    • 0017671634 scopus 로고
    • Investigations into the metabolism and mode of action of the colon carcinogen 1,2-dimethylhydrazine and azoxymethane
    • 10.1002/1097-0142(197711)40:5+<2436: AID-CNCR2820400908>3.0.CO;2-U
    • Fiala ES (1977) Investigations into the metabolism and mode of action of the colon carcinogen 1,2-dimethylhydrazine and azoxymethane. Cancer 40:436-2445
    • (1977) Cancer , vol.40 , pp. 436-2445
    • Fiala, E.S.1
  • 8
    • 0021287405 scopus 로고
    • 6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents
    • Pegg AE (1984) Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents. Cancer Invest 2:223-231 (Pubitemid 14079562)
    • (1984) Cancer Investigation , vol.2 , Issue.3 , pp. 223-231
    • Pegg, A.E.1
  • 9
    • 0023554422 scopus 로고
    • Effects of chronic dietary ethanol on in vivo and in vitro metabolism of methylazoxymethanol and on methylazoxymethanol-induced DNA methylation in rat colon and liver
    • Fiala ES, Sohn OS, Hamilton SR (1987) Effects of chronic dietary ethanol on in vivo and in vitro metabolism of methylazoxymethanol and on methylazoxymethanol-induced DNA methylation in rat colon and liver. Cancer Res 47:5939-5943 (Pubitemid 18018733)
    • (1987) Cancer Research , vol.47 , Issue.22 , pp. 5939-5943
    • Fiala, E.S.1    Sohn, O.S.2    Hamilton, S.R.3
  • 10
    • 0025289049 scopus 로고
    • Free radicals, antioxidant enzymes, and carcinogenesis
    • DOI 10.1016/0891-5849(90)90156-D
    • Sun Y (1990) Free radicals, antioxidant enzymes and carcinogenesis. Free Radic Biol Med 8:583-599 (Pubitemid 20204421)
    • (1990) Free Radical Biology and Medicine , vol.8 , Issue.6 , pp. 583-599
    • Sun, Y.1
  • 11
    • 0025046606 scopus 로고
    • 1,2-Dimethylhydrazine-induced alterations in lipid peroxidation in preneoplastic and neoplastic colonic tissues
    • DOI 10.1016/0005-2760(90)90240-X
    • Dudeja PK, Brasitus TA (1990) 1,2-Dimethyl hydrazine induced alterations in lipid peroxidation in preneoplastic and neoplastic colonic tissue. Biochem Biophys Acta 1046:267-270 (Pubitemid 20298412)
    • (1990) Biochimica et Biophysica Acta - Lipids and Lipid Metabolism , vol.1046 , Issue.3 , pp. 267-270
    • Dudeja, P.K.1    Brasitus, T.A.2
  • 12
    • 77954730556 scopus 로고    scopus 로고
    • Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1,2-dimethylhydrazine-induced rat colon carcinogenesis
    • 1:CAS:528:DC%2BC3cXhtVWksbnL 20406206 10.1111/j.1742-7843.2010.00565.x
    • Umesalma S, Sudhandiran G (2010) Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Basic Clin Pharmacol Toxicol 107:650-655
    • (2010) Basic Clin Pharmacol Toxicol , vol.107 , pp. 650-655
    • Umesalma, S.1    Sudhandiran, G.2
  • 13
    • 0030859476 scopus 로고    scopus 로고
    • The incidence of aberrant crypt foci and colonic carcinoma in dimethylhydrazine-treated rats varies in a site-specific manner and depends on tumor histology
    • Park HS, Goodlad RA, Wright NA (1997) The incidence of aberrant crypt foci and colonic carcinoma in dimethylhydrazine-treated rats varies in a site-specific manner and depends on tumor histology. Cancer Res 57:4507-4510 (Pubitemid 27441053)
    • (1997) Cancer Research , vol.57 , Issue.20 , pp. 4507-4510
    • Park, H.-S.1    Goodlad, R.A.2    Wright, N.A.3
  • 14
    • 77956630283 scopus 로고    scopus 로고
    • The neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral carcinogenesis
    • 1:CAS:528:DC%2BC3cXmtlyhu7o%3D 19458912 10.1007/s10637-009-9263-3
    • Harish Kumar G, Vidya Priyadarsini R, Vinothini G, Vidjaya Letchoumy P, Nagini S (2010) The neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral carcinogenesis. Invest New Drugs 28:392-401
    • (2010) Invest New Drugs , vol.28 , pp. 392-401
    • Harish Kumar, G.1    Vidya Priyadarsini, R.2    Vinothini, G.3    Vidjaya Letchoumy, P.4    Nagini, S.5
  • 16
    • 84879411035 scopus 로고    scopus 로고
    • Nanoencapsulation of polyphenols for protective effect against colon-rectal cancer
    • 1:CAS:528:DC%2BC38XhsFKnsbjI 22940401 10.1016/j.biotechadv.2012.08.005
    • Santos IS, Ponte BM, Boonme P, Silva AM, Souto EB (2013) Nanoencapsulation of polyphenols for protective effect against colon-rectal cancer. Biotechnol Adv 31:514-523
    • (2013) Biotechnol Adv , vol.31 , pp. 514-523
    • Santos, I.S.1    Ponte, B.M.2    Boonme, P.3    Silva, A.M.4    Souto, E.B.5
  • 17
    • 80051789298 scopus 로고    scopus 로고
    • Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease
    • 1:CAS:528:DC%2BC3MXhtVWqurzP 21763290 10.1016/j.bcp.2011.06.043
    • Rosillo MA, Sanchez-Hidalgo M, Cardeno A, Alarcon De La Lastra C (2011) Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease. Biochem Pharmacol 82:737-745
    • (2011) Biochem Pharmacol , vol.82 , pp. 737-745
    • Rosillo, M.A.1    Sanchez-Hidalgo, M.2    Cardeno, A.3    Alarcon De La Lastra, C.4
  • 18
    • 79957598613 scopus 로고    scopus 로고
    • Ellagitannins, ellagic acid and their derived metabolites: A review about source, metabolism, functions and health
    • 1:CAS:528:DC%2BC3MXntlGrtbo%3D 10.1016/j.foodres.2011.04.027
    • Landete JM (2011) Ellagitannins, ellagic acid and their derived metabolites: a review about source, metabolism, functions and health. Food Res Int 44:1150-1160
    • (2011) Food Res Int , vol.44 , pp. 1150-1160
    • Landete, J.M.1
  • 19
    • 19444379748 scopus 로고    scopus 로고
    • Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury
    • DOI 10.1203/01.PDR.0000157722.07810.15
    • Loren DJ, Seeram NP, Schulman RN, Holtzman DM (2005) Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury. Pediatr Res 57:858-864 (Pubitemid 40727118)
    • (2005) Pediatric Research , vol.57 , Issue.6 , pp. 858-864
    • Loren, D.J.1    Seeram, N.P.2    Schulman, R.N.3    Holtzman, D.M.4
  • 20
    • 84880435708 scopus 로고    scopus 로고
    • In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells
    • 1:CAS:528:DC%2BC3sXht12hs73M 23811531 10.1016/j.fct.2013.06.025
    • Qiu Z, Zhou B, Jin L, Yu H, Liu L, Liu Y, Qin C, Xie S, Zhu F (2013) In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells. Food Chem Toxicol 59:428-437
    • (2013) Food Chem Toxicol , vol.59 , pp. 428-437
    • Qiu, Z.1    Zhou, B.2    Jin, L.3    Yu, H.4    Liu, L.5    Liu, Y.6    Qin, C.7    Xie, S.8    Zhu, F.9
  • 21
    • 83455262681 scopus 로고    scopus 로고
    • The antioxidant potency of Punica granatum L. Fruit peel reduces cell proliferation and induces apoptosis on breast cancer
    • 1:CAS:528:DC%2BC3MXhsF2rtbrM 21861726 10.1089/jmf.2011.0062
    • Dikmen M, Ozturk N, Ozturk Y (2011) The antioxidant potency of Punica granatum L. Fruit peel reduces cell proliferation and induces apoptosis on breast cancer. J Med Food 14:1638-1646
    • (2011) J Med Food , vol.14 , pp. 1638-1646
    • Dikmen, M.1    Ozturk, N.2    Ozturk, Y.3
  • 22
    • 75749133579 scopus 로고    scopus 로고
    • Chemomodulation of the antioxidative enzymes and peroxidative damage in the colon of 1,2-dimethyl hydrazine-induced rats by ellagicacid
    • 10.1002/ptr.2962
    • Umesalma S, Sudhandiran G (2010) Chemomodulation of the antioxidative enzymes and peroxidative damage in the colon of 1,2-dimethyl hydrazine-induced rats by ellagicacid. Phytother Res 1:S114-S119
    • (2010) Phytother Res , vol.1
    • Umesalma, S.1    Sudhandiran, G.2
  • 23
    • 79956116511 scopus 로고    scopus 로고
    • Ellagic acid prevents rat colon carcinogenesis induced by 1,2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway
    • 1:CAS:528:DC%2BC3MXmtFantL0%3D 21463623 10.1016/j.ejphar.2011.03.036
    • Umesalma S, Sudhandiran G (2011) Ellagic acid prevents rat colon carcinogenesis induced by 1,2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway. Eur J Pharmacol 660:249-258
    • (2011) Eur J Pharmacol , vol.660 , pp. 249-258
    • Umesalma, S.1    Sudhandiran, G.2
  • 24
    • 0029069104 scopus 로고
    • Nucleolar organizer regions in adenoid cystic carcinoma of the salivary glands
    • 1:STN:280:DyaK2MzptFehuw%3D%3D 7662354
    • Yamamoto Y, Itoh T, Saka T, Takahashi H (1995) Nucleolar organizer regions in adenoid cystic carcinoma of the salivary glands. Eur Arch Otorhinolaryngol 252:176-180
    • (1995) Eur Arch Otorhinolaryngol , vol.252 , pp. 176-180
    • Yamamoto, Y.1    Itoh, T.2    Saka, T.3    Takahashi, H.4
  • 25
    • 71849104860 scopus 로고
    • Protein measurement with the folin phenol reagent
    • 1:CAS:528:DyaG38XhsVyrsw%3D%3D 14907713
    • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3    Randall, R.J.4
  • 26
    • 0001135745 scopus 로고
    • Determination of enzymes and degradation products of glycosaminoglycan metabolism in the serum of healthy and varicose subjects
    • 1:CAS:528:DyaE3sXktFWmtA%3D%3D 10.1016/0009-8981(72)90105-2
    • Niebes P (1972) Determination of enzymes and degradation products of glycosaminoglycan metabolism in the serum of healthy and varicose subjects. Clin Chim Acta 42:399-408
    • (1972) Clin Chim Acta , vol.42 , pp. 399-408
    • Niebes, P.1
  • 27
    • 0018375780 scopus 로고
    • More sensitive assay for discrimination galactosamine and glycoasmine in mixtures
    • 10.1016/0003-2697(79)90379-8
    • Wagner WD (1974) More sensitive assay for discrimination galactosamine and glycoasmine in mixtures. Anal Biochem 94:394-397
    • (1974) Anal Biochem , vol.94 , pp. 394-397
    • Wagner, W.D.1
  • 28
    • 0004717166 scopus 로고
    • Fucose and sialic acid in glycoproteins of the mucus of the digestive tract
    • 1:CAS:528:DyaF3MXivVOnsw%3D%3D 13723070
    • Dische Z (1960) Fucose and sialic acid in glycoproteins of the mucus of the digestive tract. Fed Proc 19:904-910
    • (1960) Fed Proc , vol.19 , pp. 904-910
    • Dische, Z.1
  • 29
    • 0008128130 scopus 로고
    • The thiobarbituric acid assay of sialic acids
    • 1:CAS:528:DyaG1MXhtFamtrk%3D 13672998
    • Warren L (1959) The thiobarbituric acid assay of sialic acids. J Biol Chem 234:1971-1975
    • (1959) J Biol Chem , vol.234 , pp. 1971-1975
    • Warren, L.1
  • 30
    • 77049207568 scopus 로고
    • Determination of serum glycoproteins
    • 10.1002/9780470110188.ch10
    • Winzler RJ (1995) Determination of serum glycoproteins. Meth Biochem Anal 2:279-311
    • (1995) Meth Biochem Anal , vol.2 , pp. 279-311
    • Winzler, R.J.1
  • 31
    • 0042754636 scopus 로고    scopus 로고
    • Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma
    • 1:CAS:528:DC%2BD38XpsVygurs%3D 12429983
    • Ranieri G, Labriola A, Achille G, Florio G, Zito AF, Grammatica L, Paradiso A (2002) Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma. Int J Oncol 21:1317-1323
    • (2002) Int J Oncol , vol.21 , pp. 1317-1323
    • Ranieri, G.1    Labriola, A.2    Achille, G.3    Florio, G.4    Zito, A.F.5    Grammatica, L.6    Paradiso, A.7
  • 32
    • 67349202556 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling
    • 1:CAS:528:DC%2BD1MXltlegsbc%3D 19138753 10.1016/j.pupt.2008.12.010
    • Sriram N, Kalayarasan S, Sudhandiran G (2009) Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling. Pulm Pharmacol Ther 22:221-236
    • (2009) Pulm Pharmacol Ther , vol.22 , pp. 221-236
    • Sriram, N.1    Kalayarasan, S.2    Sudhandiran, G.3
  • 33
    • 50449100139 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties
    • 1:CAS:528:DyaF2cXktF2gur8%3D 14209972
    • Omura T, Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties. J Biol Chem 239:2379-2385
    • (1964) J Biol Chem , vol.239 , pp. 2379-2385
    • Omura, T.1    Sato, R.2
  • 34
    • 0016275313 scopus 로고
    • Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation
    • 1:CAS:528:DyaE2MXltlahtg%3D%3D 4436300
    • Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 35
    • 0020597272 scopus 로고
    • UDP-glucuronosyltransferase activities. Guidelines for consistent interim terminology and assay conditions
    • DOI 10.1016/0006-2952(83)90610-X
    • Bock KW, Burchell B, Dutton GJ, Hanninen O, Mulder GJ, Owens IS, Siest G, Tephly TR (1983) UDP-glucuronosyl transferase activities: guidelines for consistent interim terminology and assay condition. Biochem Pharmacol 32:953-955 (Pubitemid 13084000)
    • (1983) Biochemical Pharmacology , vol.32 , Issue.6 , pp. 953-955
    • Bock, K.W.1    Burchell, B.2    Dutton, G.J.3
  • 36
    • 50549169947 scopus 로고
    • DT diaphorase. I. Purification from the soluble fraction of rat-liver cytoplasm, and properties
    • 1:CAS:528:DyaF38XktlWgs7c%3D 13890666 10.1016/0006-3002(62)90997-6
    • Ernster L, Danielson L, Ljunggren M (1962) DT diaphorase. I. Purification from the soluble fraction of rat-liver cytoplasm, and properties. Biochim Biophys Acta 58:171-188
    • (1962) Biochim Biophys Acta , vol.58 , pp. 171-188
    • Ernster, L.1    Danielson, L.2    Ljunggren, M.3
  • 37
    • 0028029360 scopus 로고
    • Identification of Ag-NOR proteins, markers of proliferation related to ribosomal gene activity
    • DOI 10.1006/excr.1994.1283
    • Roussel P, Hernandez-Verden D (1994) Identification of Ag-NOR proteins, makers of proliferation related to ribosomal gene activity. Exp Cell Res 214:465-472 (Pubitemid 24310804)
    • (1994) Experimental Cell Research , vol.214 , Issue.2 , pp. 465-472
    • Roussel, P.1    Hernandez-Verdun, D.2
  • 38
    • 0027203219 scopus 로고
    • Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: Suppressing effects on tumor development and biomarkers expression of colon tumorigenesis
    • Tanaka T, Kojima T, Suzui M, Mori H (1993) Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis. Cancer Res 53:3908-3913 (Pubitemid 23267687)
    • (1993) Cancer Research , vol.53 , Issue.17 , pp. 3908-3913
    • Tanaka, T.1    Kojima, T.2    Suzui, M.3    Mori, H.4
  • 39
    • 84879976165 scopus 로고    scopus 로고
    • Antiproliferative efficacy of hesperetin (citrus flavonoid) in 1,2-dimethylhydrazine-induced colon cancer
    • 1:CAS:528:DC%2BC3sXhtVKrs7zI 22899565 10.1002/ptr.4826
    • Aranganathan S, Nalini N (2013) Antiproliferative efficacy of hesperetin (citrus flavonoid) in 1,2-dimethylhydrazine-induced colon cancer. Phytother Res 27:999-1005
    • (2013) Phytother Res , vol.27 , pp. 999-1005
    • Aranganathan, S.1    Nalini, N.2
  • 40
    • 77957369598 scopus 로고    scopus 로고
    • Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro
    • 1:CAS:528:DC%2BC3cXht1GrtLjL 20811693
    • Dai Z, Nair V, Khan M, Ciolino HP (2010) Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro. Oncol Rep 24:1087-1091
    • (2010) Oncol Rep , vol.24 , pp. 1087-1091
    • Dai, Z.1    Nair, V.2    Khan, M.3    Ciolino, H.P.4
  • 41
    • 69749097044 scopus 로고    scopus 로고
    • Cyclosporine A inhibits colorectal cancer proliferation probably by regulating expression levels of c-Myc, p21 (WAF1/CIP1) and proliferating cell nuclear antigen
    • 1:CAS:528:DC%2BD1MXhtFyqs7fE 19481339 10.1016/j.canlet.2009.05.001
    • Masuo T, Okamura S, Zhang Y, Mori M (2009) Cyclosporine A inhibits colorectal cancer proliferation probably by regulating expression levels of c-Myc, p21 (WAF1/CIP1) and proliferating cell nuclear antigen. Cancer Lett 285:66-72
    • (2009) Cancer Lett , vol.285 , pp. 66-72
    • Masuo, T.1    Okamura, S.2    Zhang, Y.3    Mori, M.4
  • 42
    • 0028909205 scopus 로고
    • Expression of proliferating cell nuclear antigen in hyperplastic polyps, adenomas and inflammatory cloacogenic polyps of the large intestine
    • 1:STN:280:DyaK2M3itFKksw%3D%3D 7706518 10.1136/jcp.48.1.46
    • Carr NJ, Monihan JM, Nzeako UC, Murakata LA, Sobin LH (1995) Expression of proliferating cell nuclear antigen in hyperplastic polyps, adenomas and inflammatory cloacogenic polyps of the large intestine. J Clin Pathol 48:46-52
    • (1995) J Clin Pathol , vol.48 , pp. 46-52
    • Carr, N.J.1    Monihan, J.M.2    Nzeako, U.C.3    Murakata, L.A.4    Sobin, L.H.5
  • 43
    • 0031045565 scopus 로고    scopus 로고
    • PCNA: Structure, functions and interactions
    • Kelman Z (1997) PCNA: structure, functions and interactions. Oncogene 14:629-640 (Pubitemid 27095854)
    • (1997) Oncogene , vol.14 , Issue.6 , pp. 629-640
    • Kelman, Z.1
  • 44
    • 0026689162 scopus 로고
    • Proliferating cell nuclear antigen expression in normal, preneoplastic, and neoplastic colonic epithelium of the rat
    • 1:CAS:528:DyaK38Xks1Olt78%3D 1351857
    • Yamada K, Yoshitake K, Sato M, Ahnen DJ (1992) Proliferating cell nuclear antigen expression in normal, preneoplastic, and neoplastic colonic epithelium of the rat. Gastroenterology 103:160-167
    • (1992) Gastroenterology , vol.103 , pp. 160-167
    • Yamada, K.1    Yoshitake, K.2    Sato, M.3    Ahnen, D.J.4
  • 46
    • 40449111366 scopus 로고    scopus 로고
    • Ellagic acid suppresses oxidised low-density lipoprotein-induced aortic smooth muscle cell proliferation: Studies on the activation of extracellular signal-regulated kinase 1/2 and proliferating cell nuclear antigen expression
    • DOI 10.1017/S0007114507831734, PII S0007114507831734
    • Chang WC, Yu YM, Chiang SY, Tseng CY (2008) Ellagic acid suppresses oxidized low-density lipoprotein-induced aortic smooth muscle cell proliferation: studies on the activation of extracellular signal-regulated kinase 1/2 and proliferating cell nuclear antigen expression. Br J Nutr 99:709-714 (Pubitemid 351351623)
    • (2008) British Journal of Nutrition , vol.99 , Issue.4 , pp. 709-714
    • Chang, W.-C.1    Yu, Y.-M.2    Chiang, S.-Y.3    Tseng, C.-Y.4
  • 47
    • 0029813776 scopus 로고    scopus 로고
    • Cell surface carbohydrates as prognostic markers in human carcinomas
    • DOI 10.1002/(SICI)1096-9896(199608)179:4<358::AID-PATH564>3.0.CO;2- T
    • Dabelsteen E (1996) Cell surface carbohydrates as prognostic markers in human carcinomas. J Pathol 179:358-369 (Pubitemid 26276103)
    • (1996) Journal of Pathology , vol.179 , Issue.4 , pp. 358-369
    • Dabelsteen, E.1
  • 50
    • 69049117556 scopus 로고    scopus 로고
    • Mast cells in tumor growth: Angiogenesis, tissue remodelling and immune-modulation
    • 1:CAS:528:DC%2BD1MXhtVenurvO 2731828 19233249
    • Maltby S, Khazaie K, McNagny KM (2009) Mast cells in tumor growth: angiogenesis, tissue remodelling and immune-modulation. Biochim Biophys Acta 1796:19-26
    • (2009) Biochim Biophys Acta , vol.1796 , pp. 19-26
    • Maltby, S.1    Khazaie, K.2    McNagny, K.M.3
  • 51
    • 0028930216 scopus 로고
    • Mast cells in colorectal neoplasias and premalignant disorders
    • 1:STN:280:DyaK2M7ovVKltg%3D%3D 7882795 10.1007/BF02055605
    • Lachter J, Stein M, Lichtig C, Eidelman S, Munichor M (1995) Mast cells in colorectal neoplasias and premalignant disorders. Dis Colon Rectum 38:290-293
    • (1995) Dis Colon Rectum , vol.38 , pp. 290-293
    • Lachter, J.1    Stein, M.2    Lichtig, C.3    Eidelman, S.4    Munichor, M.5
  • 52
    • 84874112383 scopus 로고    scopus 로고
    • Mast cells and inflammation-associated colorectal carcinogenesis
    • 1:CAS:528:DC%2BC3sXisVaisrc%3D 22993030 10.1007/s00281-012-0343-7
    • Tanaka T, Ishikawa H (2013) Mast cells and inflammation-associated colorectal carcinogenesis. Semin Immunopathol 35:245-254
    • (2013) Semin Immunopathol , vol.35 , pp. 245-254
    • Tanaka, T.1    Ishikawa, H.2
  • 53
    • 66149120295 scopus 로고    scopus 로고
    • The controversial role of mast cells in tumor growth
    • 1:CAS:528:DC%2BD1MXhtVSnsbbE 19491054 10.1016/S1937-6448(09)75004-X
    • Ribatti D, Crivellato E (2009) The controversial role of mast cells in tumor growth. Int Rev Cell Mol Biol 275:89-131
    • (2009) Int Rev Cell Mol Biol , vol.275 , pp. 89-131
    • Ribatti, D.1    Crivellato, E.2
  • 55
    • 84864083373 scopus 로고    scopus 로고
    • P38α MAPK mediates 17β-estradiol inhibition of MMP-2 and -9 expression and cell migration in human lovo colon cancer cells
    • 1:CAS:528:DC%2BC38XhtVKltLbI 22377968 10.1002/jcp.24072
    • Hsu HH, Liu CJ, Shen CY, Chen YJ, Chen LM, Kuo WH, Lin YM, Chen RJ, Tsai CH, Tsai FJ, Huang CY (2012) p38α MAPK mediates 17β-estradiol inhibition of MMP-2 and -9 expression and cell migration in human lovo colon cancer cells. J Cell Physiol 227:3648-3660
    • (2012) J Cell Physiol , vol.227 , pp. 3648-3660
    • Hsu, H.H.1    Liu, C.J.2    Shen, C.Y.3    Chen, Y.J.4    Chen, L.M.5    Kuo, W.H.6    Lin, Y.M.7    Chen, R.J.8    Tsai, C.H.9    Tsai, F.J.10    Huang, C.Y.11
  • 56
    • 0032868752 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition prevents colon cancer peritoneal carcinomatosis development and prolongs survival in rats
    • DOI 10.1093/carcin/20.8.1445
    • Aparicio T, Kermorgant S, Dessirier V, Lewin MJ, Lehy T (1999) Matrix metalloproteinase inhibition prevents colon cancer peritoneal carcinomatosis development and prolongs survival in rats. Carcinogenesis 20:1445-1451 (Pubitemid 29385428)
    • (1999) Carcinogenesis , vol.20 , Issue.8 , pp. 1445-1451
    • Aparicio, T.1    Kermorgant, S.2    Dessirier, V.3    Lewin, M.J.M.4    Lehy, T.5
  • 57
    • 43249105587 scopus 로고    scopus 로고
    • Modulatory potential of ellagic acid, a natural plant polyphenol on altered lipid profile and lipid peroxidation status during alcohol-induced toxicity: A pathohistological study
    • DOI 10.1002/jbt.20226
    • Devipriya N, Sudheer AR, Vishwanathan P, Menon VP (2008) Modulatory potential of ellagic acid, a natural plant polyphenol on altered lipid profile and lipid peroxidation status during alcohol-induced toxicity: a pathohistological study. J Biochem Mol Toxicol 22:101-112 (Pubitemid 351657193)
    • (2008) Journal of Biochemical and Molecular Toxicology , vol.22 , Issue.2 , pp. 101-112
    • Devipriya, N.1    Sudheer, A.R.2    Vishwanathan, P.3    Menon, V.P.4
  • 60
    • 0642278463 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 and cyclin e in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis
    • 1:STN:280:DC%2BD3srjs1Sisw%3D%3D 14614307
    • Hur K, Kim JR, Yoon BI, Lee JK, Choi JH, Oh GT, Kim DY (2000) Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis. J Vet Sci 1:121-126
    • (2000) J Vet Sci , vol.1 , pp. 121-126
    • Hur, K.1    Kim, J.R.2    Yoon, B.I.3    Lee, J.K.4    Choi, J.H.5    Oh, G.T.6    Kim, D.Y.7
  • 61
    • 7244227675 scopus 로고    scopus 로고
    • Apoptosis and colorectal cancer
    • DOI 10.1136/gut.2004.052704
    • Watson AJ (2004) Apoptosis and colorectal cancer. Gut 53:1701-1709 (Pubitemid 39434118)
    • (2004) Gut , vol.53 , Issue.11 , pp. 1701-1709
    • Watson, A.J.M.1
  • 62
    • 70349459599 scopus 로고    scopus 로고
    • P53 and metabolism
    • 1:CAS:528:DC%2BD1MXhtFentb%2FM 19759539 10.1038/nrc2715
    • Vousden KH, Ryan KM (2009) p53 and metabolism. Nat Rev Cancer 9:691-700
    • (2009) Nat Rev Cancer , vol.9 , pp. 691-700
    • Vousden, K.H.1    Ryan, K.M.2
  • 64
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • DOI 10.1038/nature05529, PII NATURE05529
    • Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, Cordon-Cardo C, Lowe SW (2007) Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445:656-660 (Pubitemid 46232886)
    • (2007) Nature , vol.445 , Issue.7128 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3    Dickins, R.A.4    Hernando, E.5    Krizhanovsky, V.6    Cordon-Cardo, C.7    Lowe, S.W.8
  • 66
    • 33747823839 scopus 로고    scopus 로고
    • L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes
    • Banks D, Wu M, Higa LA, Gavrilova N, Quan J, Ye T, Kobayashi R, Sun H, Zhang H (2006) L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes. Cell Cycle 5:1719-1729 (Pubitemid 44285260)
    • (2006) Cell Cycle , vol.5 , Issue.15 , pp. 1719-1729
    • Banks, D.1    Wu, M.2    Higa, L.A.3    Gavrilova, N.4    Quan, J.5    Ye, T.6    Kobayashi, R.7    Sun, H.8    Zhang, H.9
  • 67
    • 0018070396 scopus 로고
    • Ultrastructure of 1,2-dimethylhydrazine-induced adenocarcinomas in rat colon
    • Barkla DH, Tutton PJ (1978) Ultrastructure of 1,2-dimethylhydrazine- induced adenocarcinomas in rat colon. J Natl Cancer Inst 61:1291-1299 (Pubitemid 9062518)
    • (1978) Journal of the National Cancer Institute , vol.61 , Issue.5 , pp. 1291-1299
    • Barkla, D.H.1    Tutton, P.J.M.2
  • 68
    • 58349093405 scopus 로고    scopus 로고
    • Pituitary toxicity but lack of rat colon carcinogenicity of a DC-magnetic field in a medium-term bioassay
    • 18439092
    • Salim EI, Omar KM, Abou-Hattab HA, Abou-Zaid FA (2008) Pituitary toxicity but lack of rat colon carcinogenicity of a DC-magnetic field in a medium-term bioassay. Asian Pac J Cancer Prev 9:131-140
    • (2008) Asian Pac J Cancer Prev , vol.9 , pp. 131-140
    • Salim, E.I.1    Omar, K.M.2    Abou-Hattab, H.A.3    Abou-Zaid, F.A.4
  • 69
    • 33144459032 scopus 로고    scopus 로고
    • Cytochrome P450 and xenobiotic receptor humanized mice
    • DOI 10.1146/annurev.pharmtox.45.120403.100007
    • Gonzalez FJ, Yu AM (2006) Cytochrome P450 and xenobiotic receptor humanized mice. Annu Rev Pharmacol Toxicol 46:41-64 (Pubitemid 43271183)
    • (2006) Annual Review of Pharmacology and Toxicology , vol.46 , pp. 41-64
    • Gonzalez, F.J.1    Yu, A.-M.2
  • 71
    • 79952453319 scopus 로고    scopus 로고
    • Effect of gallic acid on xenobiotic metabolizing enzymes in 1,2-dimethyl hydrazine induced colon carcinogenesis in Wistar rats: A chemopreventive approach
    • 10.1016/j.fct.2010.12.012
    • GiftsonSenapathy J, Jayanthi S, Viswanathan P, Umadevi P, Nalini N (2011) Effect of gallic acid on xenobiotic metabolizing enzymes in 1,2-dimethyl hydrazine induced colon carcinogenesis in Wistar rats: a chemopreventive approach. Food Chem Toxicol l49:887-892
    • (2011) Food Chem Toxicol , vol.49 , pp. 887-892
    • Giftsonsenapathy, J.1    Jayanthi, S.2    Viswanathan, P.3    Umadevi, P.4    Nalini, N.5
  • 72
    • 0026571144 scopus 로고
    • The effect of ellagic acid on xenobiotic metabolism by cytochrome P-450IIE1 and nitrosodimethylamine mutagenicity
    • 1:CAS:528:DyaK38Xht1ejtL4%3D 1730135 10.1016/0304-3835(92)90170-Z
    • Wilson T, Lewis MJ, Cha KL, Gold B (1992) The effect of ellagic acid on xenobiotic metabolism by cytochrome P-450IIE1 and nitrosodimethylamine mutagenicity. Cancer Lett 61:129-134
    • (1992) Cancer Lett , vol.61 , pp. 129-134
    • Wilson, T.1    Lewis, M.J.2    Cha, K.L.3    Gold, B.4
  • 73
    • 0033986958 scopus 로고    scopus 로고
    • 1 biotransformation
    • DOI 10.1006/phrs.1999.0544
    • Premalatha B, Sachdanandam P (2000) Modulating role of Semecarpus anacardium L. nut milk extract on Aflatoxin B1 biotransformation. Pharmacol Res 41:19-24 (Pubitemid 30008932)
    • (2000) Pharmacological Research , vol.41 , Issue.1 , pp. 19-24
    • Premalatha, B.1    Sachdanandam, P.2
  • 74
    • 0035038561 scopus 로고    scopus 로고
    • Characterization of rat and human UDP-glucuronosyltransferases responsible for the in Vitro glucuronidation of diclofenac
    • DOI 10.1093/toxsci/61.1.49
    • King C, Tang W, Ngui J, Tephly T, Braun M (2001) Characterization of rat and human UDP-glucuronosyl transferases responsible for the in vitro glucuronidation of diclofenac. Toxicol Sci 61:49-53 (Pubitemid 32409686)
    • (2001) Toxicological Sciences , vol.61 , Issue.1 , pp. 49-53
    • King, C.1    Tang, W.2    Ngui, J.3    Tephly, T.4    Braun, M.5
  • 75
    • 79958696362 scopus 로고    scopus 로고
    • Effect of red wine polyphenol dietary supplementation on two phase II enzymes in liver of hyperhomocysteinemic mice
    • 1:CAS:528:DC%2BC3MXnsVyqsLY%3D 21550378 10.1016/j.fct.2011.04.024
    • Noll C, Dairou J, Ripoll C, Paul JL, Dupret JM, Delabar JM, Rodrigues-Lima F, Janel N (2011) Effect of red wine polyphenol dietary supplementation on two phase II enzymes in liver of hyperhomocysteinemic mice. Food Chem Toxicol 49:1764-1769
    • (2011) Food Chem Toxicol , vol.49 , pp. 1764-1769
    • Noll, C.1    Dairou, J.2    Ripoll, C.3    Paul, J.L.4    Dupret, J.M.5    Delabar, J.M.6    Rodrigues-Lima, F.7    Janel, N.8
  • 76
    • 0031308138 scopus 로고    scopus 로고
    • Induction of DT-diaphorase in cancer chemoprevention and chemotherapy
    • Begleiter A, Leith MK, Curphey TJ, Doherty GP (1997) Induction of DT-diaphorase in cancer chemoprevention and chemotherapy. Oncol Res 9:371-382 (Pubitemid 127825991)
    • (1997) Oncology Research , vol.9 , Issue.6-7 , pp. 371-382
    • Begleiter, A.1    Leith, M.K.2    Curphey, T.J.3    Doherty, G.P.4
  • 77
    • 3242742185 scopus 로고    scopus 로고
    • DT-diaphorase: A target for new anticancer drugs
    • DOI 10.1016/j.ctrv.2004.01.002, PII S030573720400026X
    • Danson S, Ward TH, Butler J, Ranson M (2004) DT-diaphorase: a target for new anticancer drugs. Cancer Treat Rev 30:437-449 (Pubitemid 38968124)
    • (2004) Cancer Treatment Reviews , vol.30 , Issue.5 , pp. 437-449
    • Danson, S.1    Ward, T.H.2    Butler, J.3    Ranson, M.4
  • 78
    • 44849139348 scopus 로고    scopus 로고
    • Pretreatment with black tea polyphenols modulates xenobiotic-metabolizing enzymes in an experimental oral carcinogenesis model
    • Vidjaya Letchoumy P, Chandra Mohan KV, Stegeman JJ, Gelboin HV, Hara Y, Nagini S (2008) Pretreatment with black tea polyphenols modulates xenobiotic-metabolizing enzymes in an experimental oral carcinogenesis model. Oncol Res 17:75-85 (Pubitemid 351796814)
    • (2008) Oncology Research , vol.17 , Issue.2 , pp. 75-85
    • Vidjaya Letchoumy, P.1    Chandra Mohan, K.V.P.2    Stegeman, J.J.3    Gelboin, H.V.4    Hara, Y.5    Nagini, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.