메뉴 건너뛰기




Volumn 59, Issue , 2013, Pages 428-437

In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells

Author keywords

Antioxidant; Antiproliferative; Apoptosis; Ellagic acid; Urolithin

Indexed keywords

CASPASE 3; ELLAGIC ACID; HYDROGEN PEROXIDE; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENOL DERIVATIVE; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; UROLITHIN A; UROLITHIN B;

EID: 84880435708     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.06.025     Document Type: Article
Times cited : (119)

References (51)
  • 1
    • 3242723420 scopus 로고    scopus 로고
    • A cell-based screen for drugs to treat Huntington's disease
    • Aiken C.T., Tobin A.J., Schweitzer E.S. A cell-based screen for drugs to treat Huntington's disease. Neurobiol. Dis. 2004, 16:546-555.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 546-555
    • Aiken, C.T.1    Tobin, A.J.2    Schweitzer, E.S.3
  • 2
    • 77951941837 scopus 로고    scopus 로고
    • Bystander effects induced by chemicals and ionizing radiation: evaluation of changes in gene expression of downstream MAPK targets
    • Asur R., Balasubramaniam M., Marples B., Thomas R.A., Tucker J.D. Bystander effects induced by chemicals and ionizing radiation: evaluation of changes in gene expression of downstream MAPK targets. Mutagenesis 2010, 25:271-279.
    • (2010) Mutagenesis , vol.25 , pp. 271-279
    • Asur, R.1    Balasubramaniam, M.2    Marples, B.3    Thomas, R.A.4    Tucker, J.D.5
  • 4
    • 70449085306 scopus 로고    scopus 로고
    • Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay
    • Bialonska D., Kasimsetty S.G., Khan S.I., Ferreira D. Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay. J. Agric. Food Chem. 2009, 57:10181-10186.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 10181-10186
    • Bialonska, D.1    Kasimsetty, S.G.2    Khan, S.I.3    Ferreira, D.4
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 33746660331 scopus 로고    scopus 로고
    • P38 MAPK in development and cancer
    • Bradham C., McClay D.R. P38 MAPK in development and cancer. Cell Cycle 2006, 5:824-828.
    • (2006) Cell Cycle , vol.5 , pp. 824-828
    • Bradham, C.1    McClay, D.R.2
  • 7
    • 0034092061 scopus 로고    scopus 로고
    • Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53
    • Cai Y.C., Yang G.Y., Nie Y., Wang L.D., Zhao X., Song Y.L., Seril D.N., Liao J., Xing E.P., Yang C.S. Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53. Carcinogenesis 2000, 21:683-689.
    • (2000) Carcinogenesis , vol.21 , pp. 683-689
    • Cai, Y.C.1    Yang, G.Y.2    Nie, Y.3    Wang, L.D.4    Zhao, X.5    Song, Y.L.6    Seril, D.N.7    Liao, J.8    Xing, E.P.9    Yang, C.S.10
  • 8
    • 30044435268 scopus 로고    scopus 로고
    • Critical role of the c-JunNH2-terminal kinase and p38 mitogen-activated protein kinase pathways on sodium butyrate-induced apoptosis in DU145 human prostate cancer cells
    • Cho S.D., Ahn N.S., Jung J.W., Yang S.R., Park J.S., Lee Y.S., Jo E.H., Hwang J.W., Lii J., Kang K.S. Critical role of the c-JunNH2-terminal kinase and p38 mitogen-activated protein kinase pathways on sodium butyrate-induced apoptosis in DU145 human prostate cancer cells. Eur. J. Cancer Prev. 2006, 15:57-63.
    • (2006) Eur. J. Cancer Prev. , vol.15 , pp. 57-63
    • Cho, S.D.1    Ahn, N.S.2    Jung, J.W.3    Yang, S.R.4    Park, J.S.5    Lee, Y.S.6    Jo, E.H.7    Hwang, J.W.8    Lii, J.9    Kang, K.S.10
  • 9
    • 79952595097 scopus 로고    scopus 로고
    • The role of JNK in the development of hepatocellular carcinoma
    • Das M., Garlick D.S., Greiner D.L., Davis R.J. The role of JNK in the development of hepatocellular carcinoma. Genes Dev. 2011, 25:634-645.
    • (2011) Genes Dev. , vol.25 , pp. 634-645
    • Das, M.1    Garlick, D.S.2    Greiner, D.L.3    Davis, R.J.4
  • 10
    • 0037376674 scopus 로고    scopus 로고
    • Oxidant signals and oxidative stress
    • Finkel T. Oxidant signals and oxidative stress. Curr. Opin. Cell Biol. 2003, 15:247-254.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 247-254
    • Finkel, T.1
  • 11
    • 78649663492 scopus 로고    scopus 로고
    • Growth inhibitory, antiandrogenic, and pro-apoptotic effects of punicic acid in LNCaP human prostate cancer cells
    • Gasmi J., Sanderson J.T. Growth inhibitory, antiandrogenic, and pro-apoptotic effects of punicic acid in LNCaP human prostate cancer cells. J. Agric. Food Chem. 2010.
    • (2010) J. Agric. Food Chem.
    • Gasmi, J.1    Sanderson, J.T.2
  • 12
    • 0034909129 scopus 로고    scopus 로고
    • A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol
    • Gusman J., Malonne H., Atassi G. A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol. Carcinogenesis 2001, 22:1111-1117.
    • (2001) Carcinogenesis , vol.22 , pp. 1111-1117
    • Gusman, J.1    Malonne, H.2    Atassi, G.3
  • 13
    • 33845224136 scopus 로고    scopus 로고
    • The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin
    • Hayeshi R., Mutingwende I., Mavengere W., Masiyanise V., Mukanganyama S. The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin. Food Chem. Toxicol. 2007, 45:286-295.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 286-295
    • Hayeshi, R.1    Mutingwende, I.2    Mavengere, W.3    Masiyanise, V.4    Mukanganyama, S.5
  • 14
    • 77956468717 scopus 로고    scopus 로고
    • Failure to detect Xenotropic murine leukaemia virus-related virus in Chinese patients with chronic fatigue syndrome
    • Hong P., Li J., Li Y. Failure to detect Xenotropic murine leukaemia virus-related virus in Chinese patients with chronic fatigue syndrome. Virol. J. 2010, 7:224.
    • (2010) Virol. J. , vol.7 , pp. 224
    • Hong, P.1    Li, J.2    Li, Y.3
  • 15
    • 80052257378 scopus 로고    scopus 로고
    • Implication of the env gene of the human endogenous retrovirus W family in the expression of BDNF and DRD3 and development of recent-onset schizophrenia
    • Huang W., Li S., Hu Y., Yu H., Luo F., Zhang Q., Zhu F. Implication of the env gene of the human endogenous retrovirus W family in the expression of BDNF and DRD3 and development of recent-onset schizophrenia. Schizophr. Bull. 2011, 37:988-1000.
    • (2011) Schizophr. Bull. , vol.37 , pp. 988-1000
    • Huang, W.1    Li, S.2    Hu, Y.3    Yu, H.4    Luo, F.5    Zhang, Q.6    Zhu, F.7
  • 16
    • 33644526633 scopus 로고    scopus 로고
    • Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells
    • Itoh M., Murata T., Suzuki T., Shindoh M., Nakajima K., Imai K., Yoshida K. Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells. Oncogene 2006, 25:1195-1204.
    • (2006) Oncogene , vol.25 , pp. 1195-1204
    • Itoh, M.1    Murata, T.2    Suzuki, T.3    Shindoh, M.4    Nakajima, K.5    Imai, K.6    Yoshida, K.7
  • 17
    • 85081793921 scopus 로고    scopus 로고
    • Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model
    • Jean-Gilles D., Li L., Ma H., Yuan T., Chichester C.O., Seeram N.P. Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model. J. Agric. Food Chem. 2011.
    • (2011) J. Agric. Food Chem.
    • Jean-Gilles, D.1    Li, L.2    Ma, H.3    Yuan, T.4    Chichester, C.O.5    Seeram, N.P.6
  • 18
    • 70449124410 scopus 로고    scopus 로고
    • Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells
    • Kasimsetty S.G., Bialonska D., Reddy M.K., Thornton C., Willett K.L., Ferreira D. Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells. J. Agric. Food Chem. 2009, 57:10636-10644.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 10636-10644
    • Kasimsetty, S.G.1    Bialonska, D.2    Reddy, M.K.3    Thornton, C.4    Willett, K.L.5    Ferreira, D.6
  • 20
    • 0032782963 scopus 로고    scopus 로고
    • Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice
    • Khanduja K.L., Gandhi R.K., Pathania V., Syal N. Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice. Food Chem. Toxicol. 1999, 37:313-318.
    • (1999) Food Chem. Toxicol. , vol.37 , pp. 313-318
    • Khanduja, K.L.1    Gandhi, R.K.2    Pathania, V.3    Syal, N.4
  • 21
    • 0034746142 scopus 로고    scopus 로고
    • The NF-kappaB pathway in human endometrium and first trimester decidua
    • King A.E., Critchley H.O., Kelly R.W. The NF-kappaB pathway in human endometrium and first trimester decidua. Mol. Hum. Reprod. 2001, 7:175-183.
    • (2001) Mol. Hum. Reprod. , vol.7 , pp. 175-183
    • King, A.E.1    Critchley, H.O.2    Kelly, R.W.3
  • 22
    • 76549130383 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity
    • Kumar B., Koul S., Petersen J., Khandrika L., Hwa J.S., Meacham R.B., Wilson S., Koul H.K. P38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity. Cancer Res. 2010, 70:832-841.
    • (2010) Cancer Res. , vol.70 , pp. 832-841
    • Kumar, B.1    Koul, S.2    Petersen, J.3    Khandrika, L.4    Hwa, J.S.5    Meacham, R.B.6    Wilson, S.7    Koul, H.K.8
  • 23
    • 33747026663 scopus 로고    scopus 로고
    • The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway
    • Larrosa M., Tomas-Barberan F.A., Espin J.C. The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway. J. Nutr. Biochem. 2006, 17:611-625.
    • (2006) J. Nutr. Biochem. , vol.17 , pp. 611-625
    • Larrosa, M.1    Tomas-Barberan, F.A.2    Espin, J.C.3
  • 26
    • 84868192650 scopus 로고    scopus 로고
    • Variant 1 of KIAA0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation
    • Liu L., Chen X., Xie S., Zhang C., Qiu Z., Zhu F. Variant 1 of KIAA0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation. Hepatology 2012, 56:1760-1769.
    • (2012) Hepatology , vol.56 , pp. 1760-1769
    • Liu, L.1    Chen, X.2    Xie, S.3    Zhang, C.4    Qiu, Z.5    Zhu, F.6
  • 28
    • 66149157824 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma in bladder cancer: a promising therapeutic target
    • Mansure J.J., Nassim R., Kassouf W. Peroxisome proliferator-activated receptor gamma in bladder cancer: a promising therapeutic target. Cancer Biol. Ther. 2009, 8:6-15.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 6-15
    • Mansure, J.J.1    Nassim, R.2    Kassouf, W.3
  • 29
    • 33751260936 scopus 로고    scopus 로고
    • Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers
    • Mertens-Talcott S.U., Jilma-Stohlawetz P., Rios J., Hingorani L., Derendorf H. Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers. J. Agric. Food Chem. 2006, 54:8956-8961.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 8956-8961
    • Mertens-Talcott, S.U.1    Jilma-Stohlawetz, P.2    Rios, J.3    Hingorani, L.4    Derendorf, H.5
  • 30
    • 33746896518 scopus 로고    scopus 로고
    • Induction of cell death in Caco-2 human colon carcinoma cells by ellagic acid rich fractions from muscadine grapes (Vitis rotundifolia)
    • Mertens-Talcott S.U., Lee J.H., Percival S.S., Talcott S.T. Induction of cell death in Caco-2 human colon carcinoma cells by ellagic acid rich fractions from muscadine grapes (Vitis rotundifolia). J. Agric. Food Chem. 2006, 54:5336-5343.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 5336-5343
    • Mertens-Talcott, S.U.1    Lee, J.H.2    Percival, S.S.3    Talcott, S.T.4
  • 31
    • 35348967842 scopus 로고    scopus 로고
    • Anticancer activity of selected phenolic compounds: QSAR studies using ridge regression and neural networks
    • Nandi S., Vracko M., Bagchi M.C. Anticancer activity of selected phenolic compounds: QSAR studies using ridge regression and neural networks. Chem. Biol. Drug Des. 2007, 70:424-436.
    • (2007) Chem. Biol. Drug Des. , vol.70 , pp. 424-436
    • Nandi, S.1    Vracko, M.2    Bagchi, M.C.3
  • 32
    • 0032923360 scopus 로고    scopus 로고
    • P53/p21(WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells
    • Narayanan B.A., Geoffroy O., Willingham M.C., Re G.G., Nixon D.W. P53/p21(WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells. Cancer Lett. 1999, 136:215-221.
    • (1999) Cancer Lett. , vol.136 , pp. 215-221
    • Narayanan, B.A.1    Geoffroy, O.2    Willingham, M.C.3    Re, G.G.4    Nixon, D.W.5
  • 33
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95:351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 34
    • 0029012444 scopus 로고
    • Apoptosis and hepatobiliary disease
    • Patel T., Gores G.J. Apoptosis and hepatobiliary disease. Hepatology 1995, 21:1725-1741.
    • (1995) Hepatology , vol.21 , pp. 1725-1741
    • Patel, T.1    Gores, G.J.2
  • 36
    • 0032818585 scopus 로고    scopus 로고
    • Ras mutation, irrespective of cell type and p53 status, determines a cell's destiny to undergo apoptosis by okadaic acid, an inhibitor of protein phosphatase 1 and 2A
    • Rajesh D., Schell K., Verma A.K. Ras mutation, irrespective of cell type and p53 status, determines a cell's destiny to undergo apoptosis by okadaic acid, an inhibitor of protein phosphatase 1 and 2A. Mol. Pharmacol. 1999, 56:515-525.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 515-525
    • Rajesh, D.1    Schell, K.2    Verma, A.K.3
  • 38
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
    • Roux P.P., Blenis J. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 2004, 68:320-344.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 40
    • 33748580708 scopus 로고    scopus 로고
    • PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2
    • Schwab M., Reynders V., Ulrich S., Zahn N., Stein J., Schroder O. PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2. Apoptosis 2006, 11:1801-1811.
    • (2006) Apoptosis , vol.11 , pp. 1801-1811
    • Schwab, M.1    Reynders, V.2    Ulrich, S.3    Zahn, N.4    Stein, J.5    Schroder, O.6
  • 42
    • 68249114506 scopus 로고    scopus 로고
    • Interaction between phenolics and gut microbiota: role in human health
    • Selma M.V., Espin J.C., Tomas-Barberan F.A. Interaction between phenolics and gut microbiota: role in human health. J. Agric. Food Chem. 2009, 57:6485-6501.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 6485-6501
    • Selma, M.V.1    Espin, J.C.2    Tomas-Barberan, F.A.3
  • 43
    • 70349767241 scopus 로고    scopus 로고
    • Depleting MEKK1 expression inhibits the ability of invasion and migration of human pancreatic cancer cells
    • Su F., Li H., Yan C., Jia B., Zhang Y., Chen X. Depleting MEKK1 expression inhibits the ability of invasion and migration of human pancreatic cancer cells. J. Cancer Res. Clin. Oncol. 2009, 135:1655-1663.
    • (2009) J. Cancer Res. Clin. Oncol. , vol.135 , pp. 1655-1663
    • Su, F.1    Li, H.2    Yan, C.3    Jia, B.4    Zhang, Y.5    Chen, X.6
  • 44
    • 35349022491 scopus 로고    scopus 로고
    • Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress
    • Teng C.H., Huang W.N., Meng T.C. Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress. J. Biol. Chem. 2007, 282:28395-28407.
    • (2007) J. Biol. Chem. , vol.282 , pp. 28395-28407
    • Teng, C.H.1    Huang, W.N.2    Meng, T.C.3
  • 45
    • 33746704971 scopus 로고    scopus 로고
    • Antiproliferative effects of mistletoe (Viscum album L.) extract in urinary bladder carcinoma cell lines
    • Urech K., Buessing A., Thalmann G., Schaefermeyer H., Heusser P. Antiproliferative effects of mistletoe (Viscum album L.) extract in urinary bladder carcinoma cell lines. Anticancer Res. 2006, 26:3049-3055.
    • (2006) Anticancer Res. , vol.26 , pp. 3049-3055
    • Urech, K.1    Buessing, A.2    Thalmann, G.3    Schaefermeyer, H.4    Heusser, P.5
  • 47
    • 0033660679 scopus 로고    scopus 로고
    • Downregulation of p53 by sustained JNK activation during apoptosis
    • Wang J., Friedman E. Downregulation of p53 by sustained JNK activation during apoptosis. Mol. Carcinog. 2000, 29:179-188.
    • (2000) Mol. Carcinog. , vol.29 , pp. 179-188
    • Wang, J.1    Friedman, E.2
  • 48
    • 84864052420 scopus 로고    scopus 로고
    • Icariside II potentiates paclitaxel-induced apoptosis in human melanoma A375 cells by inhibiting TLR4 signaling pathway
    • Wu J., Guan M., Wong P.F., Yu H., Dong J., Xu J. Icariside II potentiates paclitaxel-induced apoptosis in human melanoma A375 cells by inhibiting TLR4 signaling pathway. Food Chem. Toxicol. 2012, 50:3019-3024.
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 3019-3024
    • Wu, J.1    Guan, M.2    Wong, P.F.3    Yu, H.4    Dong, J.5    Xu, J.6
  • 49
    • 37349073187 scopus 로고    scopus 로고
    • Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24)
    • Yeh C.C., Kuo H.M., Li T.M., Lin J.P., Yu F.S., Lu H.F., Chung J.G., Yang J.S. Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24). In Vivo 2007, 21:1011-1019.
    • (2007) In Vivo , vol.21 , pp. 1011-1019
    • Yeh, C.C.1    Kuo, H.M.2    Li, T.M.3    Lin, J.P.4    Yu, F.S.5    Lu, H.F.6    Chung, J.G.7    Yang, J.S.8
  • 50
    • 33751398154 scopus 로고    scopus 로고
    • Protective effect of the Chinese prescription Kangen-karyu against high glucose-induced oxidative stress in LLC-PK1 cells
    • Yokozawa T., Kim Y.A., Kim H.Y., Okamoto T., Sei Y. Protective effect of the Chinese prescription Kangen-karyu against high glucose-induced oxidative stress in LLC-PK1 cells. J. Ethnopharmacol. 2007, 109:113-120.
    • (2007) J. Ethnopharmacol. , vol.109 , pp. 113-120
    • Yokozawa, T.1    Kim, Y.A.2    Kim, H.Y.3    Okamoto, T.4    Sei, Y.5
  • 51
    • 0032483967 scopus 로고    scopus 로고
    • Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption
    • Yujiri T., Sather S., Fanger G.R., Johnson G.L. Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption. Science 1998, 282:1911-1914.
    • (1998) Science , vol.282 , pp. 1911-1914
    • Yujiri, T.1    Sather, S.2    Fanger, G.R.3    Johnson, G.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.