Cyclosporine A inhibits colorectal cancer proliferation probably by regulating expression levels of c-Myc, p21WAF1/CIP1 and proliferating cell nuclear antigen

Cancer Letters

Volumn 285, Issue 1, 2009, Pages 66-72

  Masuo, Takashige ^a   Okamura, Shinichi ^a,b   Zhang, Yajing ^a   Mori, Masatomo ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

c Myc; Calcineurin; NFAT; p21WAF1 CIP1; PCNA

Indexed keywords

CALCINEURIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLINE; CYCLOSPORIN A; MESSENGER RNA; MYC PROTEIN; TRANSCRIPTION FACTOR NFAT;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER STAGING; CANCER TISSUE; CELL FRACTIONATION; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN HT29; CELL VIABILITY; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CALCINEURIN; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLOOXYGENASE 2; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; MALE; MIDDLE AGED; NFATC TRANSCRIPTION FACTORS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 69749097044     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.05.001     Document Type: Article

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