Solvent-accessible surface area: How well can be applied to hot-spot detection?

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 3, 2014, Pages 479-490

  Martins, João M ^a   Ramos, Rui M ^a   Pimenta, António C ^a   Moreira, Irina S ^a  

^a Campus Universitário de Santiago   (Portugal)

Author keywords

Computational alanine scanning mutagenesis; Feature based algorithms; Hot spot; Solvent accessible surface area; Support vector machine

Indexed keywords

PROTEIN; SOLVENT; WATER;

ACCURACY; ARTICLE; HUMAN; HYDROGEN BOND; MACHINE LEARNING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECALL; SIMULATION; SOLVENT ACCESSIBLE SURFACE AREA; STANDARDIZATION; STATIC ELECTRICITY; SUPPORT VECTOR MACHINE; SURFACE PROPERTY;

SASA;

COMPUTATIONAL ALANINE SCANNING MUTAGENESIS; FEATURE BASED ALGORITHMS; HOT-SPOT; SOLVENT ACCESSIBLE SURFACE AREA; SUPPORT VECTOR MACHINE;

COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; MOLECULAR DYNAMICS SIMULATION; PROTEINS; SOLVENTS; SUPPORT VECTOR MACHINES; SURFACE PROPERTIES; THERMODYNAMICS;

EID: 84893763780     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24413     Document Type: Article

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