Knockdown of interleukin-1 receptor type-1 on endothelial cells attenuated stress-induced neuroinflammation and prevented anxiety-like behavior

Journal of Neuroscience

Volumn 34, Issue 7, 2014, Pages 2583-2591

  Wohleb, Eric S ^a   Patterson, Jenna M ^a   Sharma, Vikram ^a   Quan, Ning ^a   Godbout, Jonathan P ^a   Sheridan, John F ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Anxiety; Blood brain barrier; Interleukin 1; Microglia; Neuroinflammation; Stress

Indexed keywords

ANXIETY; BLOOD-BRAIN BARRIER; INTERLEUKIN-1; MICROGLIA; NEUROINFLAMMATION; STRESS;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIAL CELLS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; INTERLEUKIN-1; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-1 TYPE I; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL;

EID: 84893684095     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3723-13.2014     Document Type: Article

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