Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice

Psychoneuroendocrinology

Volumn 37, Issue 9, 2012, Pages 1491-1505

  Wohleb, Eric S ^a   Fenn, Ashley M ^a   Pacenta, Ann M ^a   Powell, Nicole D ^a   Sheridan, John F ^a   Godbout, Jonathan P ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Anxiety; Cytokines; LPS; Microglia; Sickness; Stress

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN CELL; CD14 GENE; CELL ACTIVATION; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE RESPONSE; EXPLORATORY BEHAVIOR; GENE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; INNATE IMMUNITY; INTERLEUKIN 1BETA GENE; LOCOMOTION; MACROPHAGE; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PSYCHOSOCIAL WITHDRAWAL; REPEATED SOCIAL DEFEAT; SOCIAL STRESS; TUMOR NECROSIS FACTOR ALPHA GENE; UPREGULATION; WEIGHT REDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CELL COUNT; DOMINANCE-SUBORDINATION; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICROGLIA; NITRIC OXIDE SYNTHASE TYPE II; SOCIAL ISOLATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84864747783     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2012.02.003     Document Type: Article

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