N-Ethyl-N-nitrosourea mutagenesis in the mouse provides strong genetic and in vivo evidence for the role of the Caspase Recruitment Domain (CARD) of CARD-MAGUK1 in T regulatory cell development

Immunology

Volumn 141, Issue 3, 2014, Pages 446-456

  Salisbury, Emma M ^a   Wang, Lihui ^b   Choi, Onjee ^c   Rutschmann, Sophie ^a   Ashton Rickardt, Philip G ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Regulatory T cells; Signalling signal transduction; Thymus

Indexed keywords

CASPASE RECRUITMENT DOMAIN OF CARD AMGUK1 PROTEIN; ETHYLNITROSOUREA; PROTEIN BCL 10; SCAFFOLD PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENETIC ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; INHERITANCE; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; MUTANT; NONHUMAN; PHENOTYPIC VARIATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; THYMUS; WILD TYPE;

REGULATORY T CELLS; SIGNALLING/SIGNAL TRANSDUCTION; THYMUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AUTOIMMUNITY; CARD SIGNALING ADAPTOR PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; ETHYLNITROSOUREA; GENOTYPE; HEREDITY; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUTAGENS; MUTATION; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; THYMOCYTES; THYMUS GLAND;

EID: 84893568419     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12207     Document Type: Article

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