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Volumn 141, Issue 3, 2014, Pages 431-445

The ThPOK transcription factor differentially affects the development and function of self-specific CD8+ T cells and regulatory CD4+ T cells

Author keywords

Forkhead box protein 3; Regulatory T cells; Self specific CD8 T cells; ThPOK

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GRANZYME B; HERMES ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR THPOK; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 84893529356     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12205     Document Type: Article
Times cited : (5)

References (53)
  • 1
    • 2442708080 scopus 로고    scopus 로고
    • CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision
    • Singer A, Bosselut R. CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision. Adv Immunol 2004; 83:91-131.
    • (2004) Adv Immunol , vol.83 , pp. 91-131
    • Singer, A.1    Bosselut, R.2
  • 3
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • Taniuchi I, Osato M, Egawa T, Sunshine MJ, Bae SC, Komori T, Ito Y, Littman DR. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 2002; 111:621-33.
    • (2002) Cell , vol.111 , pp. 621-633
    • Taniuchi, I.1    Osato, M.2    Egawa, T.3    Sunshine, M.J.4    Bae, S.C.5    Komori, T.6    Ito, Y.7    Littman, D.R.8
  • 4
    • 14544288635 scopus 로고    scopus 로고
    • The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
    • He X, Dave VP, Zhang Y et al. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 2005; 433:826-33.
    • (2005) Nature , vol.433 , pp. 826-833
    • He, X.1    Dave, V.P.2    Zhang, Y.3
  • 8
    • 34547744867 scopus 로고    scopus 로고
    • The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells
    • Egawa T, Tillman RE, Naoe Y, Taniuchi I, Littman DR. The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells. J Exp Med 2007; 204:1945-57.
    • (2007) J Exp Med , vol.204 , pp. 1945-1957
    • Egawa, T.1    Tillman, R.E.2    Naoe, Y.3    Taniuchi, I.4    Littman, D.R.5
  • 12
    • 0024505883 scopus 로고
    • Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules
    • Teh HS, Kishi H, Scott B, Von Boehmer H. Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules. J Exp Med 1989; 169:795-806.
    • (1989) J Exp Med , vol.169 , pp. 795-806
    • Teh, H.S.1    Kishi, H.2    Scott, B.3    Von Boehmer, H.4
  • 14
    • 4644221125 scopus 로고    scopus 로고
    • Self-reactive memory-phenotype CD8 T cells exhibit both MHC-restricted and non-MHC-restricted cytotoxicity: a role for the T-cell receptor and natural killer cell receptors
    • Dhanji S, Teh SJ, Oble D, Priatel JJ, Teh HS. Self-reactive memory-phenotype CD8 T cells exhibit both MHC-restricted and non-MHC-restricted cytotoxicity: a role for the T-cell receptor and natural killer cell receptors. Blood 2004; 104:2116-23.
    • (2004) Blood , vol.104 , pp. 2116-2123
    • Dhanji, S.1    Teh, S.J.2    Oble, D.3    Priatel, J.J.4    Teh, H.S.5
  • 15
    • 0141989779 scopus 로고    scopus 로고
    • high cells express both adaptive and innate immune system receptors and demonstrate specificity for syngeneic tumor cells
    • high cells express both adaptive and innate immune system receptors and demonstrate specificity for syngeneic tumor cells. J Immunol 2003; 171:3442-50.
    • (2003) J Immunol , vol.171 , pp. 3442-3450
    • Dhanji, S.1    Teh, H.S.2
  • 17
    • 44449127238 scopus 로고    scopus 로고
    • Preferential development of CD4 and CD8 T regulatory cells in RasGRP1-deficient mice
    • Chen X, Priatel JJ, Chow MT, Teh HS. Preferential development of CD4 and CD8 T regulatory cells in RasGRP1-deficient mice. J Immunol 2008; 180:5973-82.
    • (2008) J Immunol , vol.180 , pp. 5973-5982
    • Chen, X.1    Priatel, J.J.2    Chow, M.T.3    Teh, H.S.4
  • 19
    • 33745986018 scopus 로고    scopus 로고
    • + T cell lineages in mice deficient for the Tec kinases Itk and Rlk
    • + T cell lineages in mice deficient for the Tec kinases Itk and Rlk. Immunity 2006; 25:93-104.
    • (2006) Immunity , vol.25 , pp. 93-104
    • Broussard, C.1    Fleischacker, C.2    Horai, R.3
  • 23
    • 70349448417 scopus 로고    scopus 로고
    • Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation
    • Marks BR, Nowyhed HN, Choi JY, Poholek AC, Odegard JM, Flavell RA, Craft J. Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation. Nat Immunol 2009; 10:1125-32.
    • (2009) Nat Immunol , vol.10 , pp. 1125-1132
    • Marks, B.R.1    Nowyhed, H.N.2    Choi, J.Y.3    Poholek, A.C.4    Odegard, J.M.5    Flavell, R.A.6    Craft, J.7
  • 24
    • 0034716925 scopus 로고    scopus 로고
    • Cells: key controllers of immunologic self-tolerance
    • Sakaguchi S, Regulatory T. Cells: key controllers of immunologic self-tolerance. Cell 2000; 101:455-8.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1    Regulatory, T.2
  • 25
    • 16844365788 scopus 로고    scopus 로고
    • + regulatory T cells in immunological tolerance to self and non-self
    • + regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005; 6:345-52.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 26
    • 0035806276 scopus 로고    scopus 로고
    • + immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
    • + immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med 2001; 193:1311-8.
    • (2001) J Exp Med , vol.193 , pp. 1311-1318
    • Taylor, P.A.1    Noelle, R.J.2    Blazar, B.R.3
  • 27
    • 0031939403 scopus 로고    scopus 로고
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol 1998; 160:1212-8.
    • (1998) J Immunol , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 28
    • 0035903324 scopus 로고    scopus 로고
    • + regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • + regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 2001; 194:823-32.
    • (2001) J Exp Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3
  • 29
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299:1057-61.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 32
    • 34248592104 scopus 로고    scopus 로고
    • T cell-produced transforming growth factor-β1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation
    • Li MO, Wan YY, Flavell RA. T cell-produced transforming growth factor-β1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity 2007; 26:579-91.
    • (2007) Immunity , vol.26 , pp. 579-591
    • Li, M.O.1    Wan, Y.Y.2    Flavell, R.A.3
  • 33
    • 51649112340 scopus 로고    scopus 로고
    • T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance
    • Pesu M, Watford WT, Wei L et al. T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance. Nature 2008; 455:246-50.
    • (2008) Nature , vol.455 , pp. 246-250
    • Pesu, M.1    Watford, W.T.2    Wei, L.3
  • 34
    • 65549136983 scopus 로고    scopus 로고
    • + T regulatory cell-mediated suppression
    • + T regulatory cell-mediated suppression. Immunity 2009; 30:636-45.
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 38
    • 33847153126 scopus 로고    scopus 로고
    • Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation
    • Jenkinson SR, Intlekofer AM, Sun G, Feigenbaum L, Reiner SL, Bosselut R. Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. J Exp Med 2007; 204:267-72.
    • (2007) J Exp Med , vol.204 , pp. 267-272
    • Jenkinson, S.R.1    Intlekofer, A.M.2    Sun, G.3    Feigenbaum, L.4    Reiner, S.L.5    Bosselut, R.6
  • 39
    • 0023813094 scopus 로고
    • Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells
    • Teh HS, Kisielow P, Scott B, Kishi H, Uematsu Y, Bluthmann H, von Boehmer H. Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells. Nature 1988; 335:229-33.
    • (1988) Nature , vol.335 , pp. 229-233
    • Teh, H.S.1    Kisielow, P.2    Scott, B.3    Kishi, H.4    Uematsu, Y.5    Bluthmann, H.6    von Boehmer, H.7
  • 40
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol 2007; 8:191-7.
    • (2007) Nat Immunol , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 41
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • Winer J, Jung CK, Shackel I, Williams PM. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999; 270:41-9.
    • (1999) Anal Biochem , vol.270 , pp. 41-49
    • Winer, J.1    Jung, C.K.2    Shackel, I.3    Williams, P.M.4
  • 42
    • 0242410712 scopus 로고    scopus 로고
    • + T cell function by the transcription factor Eomesodermin
    • + T cell function by the transcription factor Eomesodermin. Science 2003; 302:1041-3.
    • (2003) Science , vol.302 , pp. 1041-1043
    • Pearce, E.L.1    Mullen, A.C.2    Martins, G.A.3
  • 43
    • 33745298220 scopus 로고    scopus 로고
    • Self-antigen maintains the innate antibacterial function of self-specific CD8 T cells in vivo
    • Dhanji S, Chow MT, Teh HS. Self-antigen maintains the innate antibacterial function of self-specific CD8 T cells in vivo. J Immunol 2006; 177:138-46.
    • (2006) J Immunol , vol.177 , pp. 138-146
    • Dhanji, S.1    Chow, M.T.2    Teh, H.S.3
  • 45
    • 0033527615 scopus 로고    scopus 로고
    • Regulation of lineage commitment distinct from positive selection
    • Keefe R, Dave V, Allman D, Wiest D, Kappes DJ. Regulation of lineage commitment distinct from positive selection. Science 1999; 286:1149-53.
    • (1999) Science , vol.286 , pp. 1149-1153
    • Keefe, R.1    Dave, V.2    Allman, D.3    Wiest, D.4    Kappes, D.J.5
  • 47
    • 15444374646 scopus 로고    scopus 로고
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 2005; 201:723-35.
    • (2005) J Exp Med , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 48
    • 0026708669 scopus 로고
    • Post-transcriptional regulation of the human transforming growth factor-β1 gene
    • Kim SJ, Park K, Koeller D et al. Post-transcriptional regulation of the human transforming growth factor-β1 gene. J Biol Chem 1992; 267:13702-7.
    • (1992) J Biol Chem , vol.267 , pp. 13702-13707
    • Kim, S.J.1    Park, K.2    Koeller, D.3
  • 49
    • 0027220013 scopus 로고
    • An element of the transforming growth factor-β1 5'-untranslated region represses translation and specifically binds a cytosolic factor
    • Romeo DS, Park K, Roberts AB, Sporn MB, Kim SJ. An element of the transforming growth factor-β1 5'-untranslated region represses translation and specifically binds a cytosolic factor. Mol Endocrinol 1993; 7:759-66.
    • (1993) Mol Endocrinol , vol.7 , pp. 759-766
    • Romeo, D.S.1    Park, K.2    Roberts, A.B.3    Sporn, M.B.4    Kim, S.J.5
  • 50
    • 0032413881 scopus 로고    scopus 로고
    • Translational control elements in the major human transforming growth factor-β1 mRNA
    • Allison RS, Mumy ML, Wakefield LM. Translational control elements in the major human transforming growth factor-β1 mRNA. Growth Factors 1998; 16:89-100.
    • (1998) Growth Factors , vol.16 , pp. 89-100
    • Allison, R.S.1    Mumy, M.L.2    Wakefield, L.M.3
  • 52
    • 0028266931 scopus 로고
    • mRNA translation: influence of the 5' and 3' untranslated regions
    • Sonenberg N. mRNA translation: influence of the 5' and 3' untranslated regions. Curr Opin Genet Dev 1994; 4:310-5.
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 310-315
    • Sonenberg, N.1
  • 53
    • 0027322840 scopus 로고
    • A GC-rich domain with bifunctional effects on mRNA and protein levels: implications for control of transforming growth factor β1 expression
    • Scotto L, Assoian RK. A GC-rich domain with bifunctional effects on mRNA and protein levels: implications for control of transforming growth factor β1 expression. Mol Cell Biol 1993; 13:3588-97.
    • (1993) Mol Cell Biol , vol.13 , pp. 3588-3597
    • Scotto, L.1    Assoian, R.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.