Regulation of glucagon secretion in normal and diabetic human islets by γ-hydroxybutyrate and glycine

Journal of Biological Chemistry

Volumn 288, Issue 6, 2013, Pages 3938-3951

  Li, Changhong ^a,d   Liu, Chengyang ^c   Nissim, Itzhak ^b,c   Chen, Jie ^a   Chen, Pan ^a   Doliba, Nicolai ^c,d   Zhang, Tingting ^a   Nissim, Iiana ^b   Daikhin, Yevgeny ^b   Stokes, David ^a   Yudkoff, Marc ^b   Bennett, Michael J ^a   Stanley, Charles A ^a,d   Insky, Franz M Matsch ^c,d   Naji, Ali ^c,d  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b Division of Infectious Diseases   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON SECRETION; GLYCINE RECEPTOR; HUMAN ISLETS; HYDROXYBUTYRATE; INSULIN SECRETION; METABOLOMICS; PANCREATIC ISLET; PARACRINE; RESPIRATORY RATE; SECOND GROUP;

AMINO ACIDS; CELLS; CYTOLOGY; INSULIN; NEUROPHYSIOLOGY;

GLUCOSE;

4 AMINOBUTYRIC ACID; 4 HYDROXYBUTYRIC ACID; ALANINE; ASPARTIC ACID; GLUCAGON; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; GLYCINE RECEPTOR; INSULIN; ISOLEUCINE; LEUCINE; MEMBRANE RECEPTOR; NEUROTRANSMITTER; REGULATOR PROTEIN; SERINE;

AMINO ACID SYNTHESIS; ARTICLE; BREATHING RATE; CELL ACTIVITY; CELL FUNCTION; CELL LEVEL; CELL STIMULATION; CELLULAR SECRETION; CONTROLLED STUDY; GLUCAGON RELEASE; GLUCONEOGENESIS; HORMONE INHIBITION; HORMONE RESPONSE; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RELEASE; MOLECULAR MECHANICS; NEUROTRANSMITTER RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN INTERACTION; REGULATORY MECHANISM;

ADULT; DIABETES MELLITUS, TYPE 2; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE; GLYCINE; HUMANS; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; RECEPTORS, GABA; RECEPTORS, GLYCINE; SODIUM OXYBATE;

EID: 84873410829     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.385682     Document Type: Article

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